Instructions for use of the drug Benalgin and reviews

Prohibited during pregnancy

Prohibited during breastfeeding

Has restrictions for children

Has restrictions for older people

Has limitations for liver problems

Has limitations for kidney problems

During illness, a person inevitably faces two symptoms - fever and pain. They are caused by the reactivity of the body and its response to inflammation. By increasing the temperature, the synthesis of interleukins is enhanced, as well as the production of leukocytes is stimulated. Despite this, an increase in body temperature reduces a person’s performance, makes him lethargic and apathetic, and lowers his mood.

A critical increase in temperature above 39 degrees leads to blood thickening and can lead to death.

There are many known ways to combat fever - a cold compress, hot tea, but in this way it will only be possible to alleviate the condition slightly, but not completely cure it. For a complex effect, it is necessary to take medications, one of which is Benalgin. This is a combination remedy that effectively relieves cold symptoms. According to the instructions for use, Benalgin can be used for adults and adolescent children.

Benalgin

The tablets contain active ingredients: metamizole sodium, caffeine and thiamine hydrochloride.

Additional ingredients: gelatin, wheat starch, cellulose, silicon dioxide, talc, magnesium stearate.

Release form

Benalgin is produced in the form of tablets, 10 pieces in blisters, 2 blisters in a cardboard pack.

pharmachologic effect

This combined drug exhibits analgesic, antipyretic and anti-inflammatory effects.

Pharmacodynamics and pharmacokinetics

The substances that make up this drug determine its effect. Thus, metamizole sodium is characterized by an analgesic, antipyretic and anti-inflammatory effect related to the inhibition of prostaglandin synthesis in the nervous system, as well as enhancing the production of beta-endorphins.

Thiamine hydrochloride or vitamin B1 is a metabolic participant, helping to improve neuroreflex regulation.

Caffeine has an anti-migraine and psychostimulating effect, due to which the blood vessels of the brain are toned and the vasomotor center is excited. In addition, there was an improvement in performance, a decrease in fatigue and drowsiness.

Indications for use

Benalgin tablets are prescribed for moderate or mild pain:

• headache, toothache, migraine pain;
• neuralgia, myalgia;
• colds accompanied by fever;
• joint pain, radicular syndrome, dysmenorrhea.

It is also possible to use the drug in combination with atropine-like or antispasmodic drugs to treat patients with mild pain in the kidneys, biliary colic and intestinal spasms.

Contraindications

Taking the drug is not recommended for:

• high sensitivity to its components;
• under 12 years of age;
• severe liver or kidney dysfunction;
• bronchospasms;
• lactation, pregnancy;
• genetic absence of glucose-6-phosphate dehydrogenase;
• diseases of the blood system;
• insomnia;
• severe forms of hypertension, atherosclerosis, intraocular pressure.

Side effects

Treatment with Benalgin can lead to the development of allergic reactions: skin rash, itching, Quincke's edema, anaphylactic shock, bronchospasm.

Problems with sleep and increased heart rate are also possible.

Benalgin, instructions for use (Method and dosage)

The tablets are taken orally after eating, one tablet 2-3 times a day, preferably in the first half. The maximum permissible single dosage is 2 tablets, daily up to 6 tablets. You can take the medicine for no more than 1-2 days.

For children aged 12-16 years, 0.5-1 tablets are prescribed 2-3 times a day, no more than 4 tablets per day.

These tablets can be taken for up to 5 days as a pain reliever and for up to 3 days as an antipyretic drug. Increasing the dosage and duration of therapy is possible only on the recommendation of a doctor.

Overdose

Long-term use of tablets can lead to disturbances in the functioning of the blood system in the form of thrombocytopenia, leukopenia and agranulocytosis.

It is also possible that symptoms may appear: nausea, vomiting, epigastric pain, mental and motor agitation, tachycardia, heart rhythm disturbances, decreased diuresis, epileptiform convulsions.

In this case, urgent medical attention is needed and treatment is carried out: gastric lavage, administration of adsorbents and other symptomatic therapy.

Interaction

With the simultaneous use of Benalgin and various non-narcotic analgesics, NSAIDs, mutual enhancement of the toxic effect is possible.

Some tricyclic antidepressants, Allopurinol and oral contraceptives can disrupt the metabolism of metamizole sodium in the liver, increasing the toxicity of this substance.

Barbiturates, Phenylbutazone and other inducers of microsomal liver enzymes can weaken the effect of Benalgin.

Combination with Cyclosporine reduces the level of its content in the blood.

Various tranquilizers and sedatives can enhance the analgesic effect of this drug.

special instructions

Overdose symptoms may occur if you consume caffeine-containing products such as tea or coffee in excess.

Caution and medical supervision are required when treating patients with liver or kidney dysfunction.

There have been cases of changes in the results of doping control tests in athletes.

Patients suffering from various forms of hay fever and atopic bronchial asthma may experience hypersensitivity reactions.

While taking Benalgin, you should avoid driving and other potentially dangerous activities that require high concentration and quick reactions.

Storage conditions

Tablets should be stored in a cool, dry place, out of reach of children, at room temperature.

Alcohol

Simultaneous use of the drug with any alcohol-containing drinks may cause the development of undesirable effects.

Benalgin price, where to buy

The price of Benalgin tablets is 50-70 rubles. You can buy tablets at any Russian pharmacy.

INFORM YOUR DOCTOR IF YOU EXPERIENCE ANY ADVERSE REACTIONS OR SENSATIONS, INCLUDING THOSE NOT MENTIONED IN THIS INSTRUCTION! AND ALSO ABOUT CHANGES IN LABORATORY INDICATORS DUE TO DRUG TAKEN!

Source: https://super-pharma.ru/drugs/1693-benalgin.html

Contraindications

Taking the drug is not recommended for:

• high sensitivity to its components;
• under 12 years of age;
• severe liver or kidney dysfunction;
• bronchospasms;
• lactation, pregnancy;
• genetic absence of glucose-6-phosphate dehydrogenase;
• diseases of the blood ;
• insomnia;
• severe forms of hypertension, atherosclerosis, intraocular pressure.

Benalgin: instructions and indications, price, analogues, reviews

To relieve acute pain, reduce inflammation and relax smooth muscles, symptomatic therapy can be used.

A popular drug that has a combination effect is Benalgin .

Its action is due to the unique combination of components included in the composition.

It contains analgesic, vasoconstrictor substances, vitamins, and components that have a stimulating activity on the central nervous system.

But doctors do not recommend taking Benalgin uncontrollably. It is important to adhere to the recommendations specified in the instructions for use. Particular attention is paid if treatment requires combining the use of Benalgin and other medications.

Instructions for use

Benalgin is an analgesic, antipyretic, and drug that affects the central nervous system.

Release form, composition

The drug Benalgin is produced in tablet .

Each of them includes:

• 500 mg metamizole sodium;
• 50 mg caffeine;
• 38.75 mg thiamine (vitamin B1).

Tablets are packaged in 10 pcs. in cellular packages.

Directions for use, dosage

Benalgin tablets should be taken after meals and washed down with plenty of water. In standard cases, adults are prescribed 1 tablet three times a day , but it is advisable to take them all in the first half of the day. If necessary, the dose can be increased, the maximum permissible daily amount is 6 tablets.

Children aged 12-16 years can be given ½–1 tablet three times a day. The maximum allowed amount is 4 tablets .

The course of therapy with Benalgin should not exceed 3 days.

Interaction with other drugs

Combination with non-steroidal anti-inflammatory drugs and non-narcotic analgesics can lead to a mutual increase in toxic effects on the body.

Oral contraceptives , tricyclic antidepressants, Allopurinol can lead to increased toxicity of metamizole due to disruption of its metabolism in the liver.

Phenylbutazone , drugs from the barbiturate group weaken the effect of metamizole.

Tranquilizers and sedatives can enhance the analgesic effect of Benalgin.

The drug reduces the concentration of cyclosporine. And as part of the blood, it can be dangerous for patients who have transplants.

Side effects

Complications may occur during treatment with Benalgin.

Side effects of the tablets include:

Disturbances in the functioning of the hematopoietic organs usually appear with long-term use of Benalgin. The occurrence of side effects should be reported to the doctor who prescribed the pills.

During pregnancy and lactation

Benalgin is contraindicated in women who are pregnant or breastfeeding..

Effect on concentration

Patients are advised to refrain from driving vehicles or dangerous machinery. You should avoid all types of activities that require a high concentration of attention and require a high speed of psychomotor reactions.

Use in childhood

Benalgin is not allowed to be given to children under 12 years of age. At the age of 12-16 years, you can give ½-1 tablet.

If kidney function is impaired

For patients with impaired renal function, Benalgin is prescribed with caution. The patient must be under medical supervision during the treatment period.

In case of liver dysfunction

For people whose liver does not perform all its functions, Benalgin tablets are prescribed only if it is possible to organize constant medical monitoring of the patient’s condition.

Storage conditions and periods

The tablets must be used within 3 years from the date of issue. They should be stored at a temperature of 15-25 °C.

Price

Benalgin is a prescription drug. But it is now difficult to find it for free sale in Russia and Ukraine. The drug is not available in pharmacies .

Analogs

The pharmaceutical equivalent of Benalgin is the drug Sedalgin Plus . These tablets have identical composition. You can buy a pack of 10 tablets of Sedalgin Plus for 95 rubles. The same components are included in the composition of Benamil-M tablets.

Substitutes for Benalgin also include the following drugs::

• Andipal-V;
• Andipal-Extra;
• Andipal-Forte;
• Analgin-Quinine;
• Kofalgin;
• Revalgin;
• 5 giraffe;
• Pentalgin;
• Analgin;
• Antifen IC.

But it is better to select a replacement in consultation with the treating doctor.

: “Painkillers for back pain”

Reviews

Judging by the reviews, Benalgin tablets are effective . With their help, you can quickly get rid of headaches, joint pain, and relieve spasms of smooth muscles. The product is a modern analogue of Analgin.

Among the main advantages, many patients who have taken Benalgin note its low cost. But it can only be used as a means of symptomatic therapy. You cannot drink Benalgin on an ongoing basis. Although patients who, due to the nature of the pain, were prescribed long-term therapy with painkillers, note that Benalgin is not addictive.

If you have had experience using Benalgin tablets, help other site visitors decide whether they are worth buying, leave your review about the drug.

Conclusion

To reduce the severity of acute pain and reduce temperature, you can use Benalgin . This is a combination drug that, in addition to pain relief, has antispasmodic, antipyretic, and anti-inflammatory effects.

• The main components of Benalgin tablets are metamizole sodium, caffeine, thiamine.
• The drug is prescribed to patients with fever, headache, toothache, and joint pain. With its help, the condition of periodic pain in women and neuralgia is alleviated.
• You should take 1 tablet no more than 3 times a day. Due to the caffeine content, it is not recommended to drink this product at night. If necessary, you are allowed to take up to 6 tablets per day.
• If side effects occur (dizziness, excitability, disturbances in the digestive system), you should consult your doctor and decide whether to continue using Benalgin for treatment.
• Before taking it, you should read the list of contraindications. Tablets are not prescribed to people with insomnia, high blood pressure, or atherosclerosis. It is forbidden to give them to children under 12 years of age, pregnant women, and nursing mothers.
• Judging by patient reviews, Benalgin tablets are effective. But it is not recommended to drink them for a long time.

Source: https://SpinaTitana.com/preparaty/drugie-preparaty/benalgin-instruktsiya.html

Benalgin: instructions for use, reviews and analogues

During illness, a person inevitably faces two symptoms - fever and pain. They are caused by the reactivity of the body and its response to inflammation.

By increasing the temperature, the synthesis of interleukins is enhanced, as well as the production of leukocytes is stimulated.

Despite this, an increase in body temperature reduces a person’s performance, makes him lethargic and apathetic, and lowers his mood.

A critical increase in temperature above 39 degrees leads to blood thickening and can lead to death.

There are many known ways to combat fever - a cold compress, hot tea, but in this way it will only be possible to alleviate the condition slightly, but not completely cure it.

For a complex effect, it is necessary to take medications, one of which is Benalgin. This is a combination remedy that effectively relieves cold symptoms.

According to the instructions for use, Benalgin can be used for adults and adolescent children.

General information about the drug

The drug is produced by the Bulgarian pharmaceutical company Balkanpharma-Dupnitza, AD. It has analgesic and antipyretic properties, and also has an anti-inflammatory effect. INN – Metamizole sodium+Caffeine+Thiamine. Possessing a wide range of therapeutic effects, the drug is used in almost all medical fields.

Release forms and prices for the drug, average in Russia

To date, there is no information on the price of Benalgin in the pharmacy chain in the Russian Federation. In Ukraine, the drug is sold in the price category from 30 to 50 UAH. Below are the average prices for drug analogues that are available in the Russian Federation.

Drug Release form Price (RUB) Country of origin

Instructions for use of the drug Toff Plus and reviews about it

Composition and pharmacological properties

Benalgin consists of three components at once, each of which causes a therapeutic effect, complementing and enhancing the effect of each other:

1. Metamizole sodium. Refers to non-steroidal anti-inflammatory drugs. The mechanism of its action is associated with inhibition of the formation of cyclooxygenase, disruption of the metabolism of arachidonic acid, which in turn leads to a decrease in the production of prostaglandins. In this way, the antipyretic and analgesic effect is realized. Analgesia occurs by reducing the activity of neurons in the dorsal sensory roots of the spinal cord.
2. Caffeine. Stimulates the central nervous system by interacting with purine receptors in the brain by stimulating them. Caffeine increases the concentration of cAMP in cells, which leads to increased glycogenolysis in the central nervous system.

   In Benalgin, caffeine potentiates the action of metamizole sodium and facilitates the penetration of its active components through the biological barriers of the body, and also has a pronounced vasoconstrictor effect.

3. Thiamine hydrochloride. It reduces inflammatory reactions in CNS cells. Thiamine also inhibits the action of cholinesterase, which facilitates the conduction of nerve impulses and, at high dosages, produces a pronounced analgesic effect.

The complex effect of the drug provides not only symptomatic relief, but also helps accelerate regeneration processes in the nervous system and restores normal blood supply.

The drug immediately affects 3 links in the occurrence of pain and fever. First of all, there is an effect on the source of inflammation and the level of prostaglandins E2 decreases, then the speed of transmission of the electrical impulse along the sensitive dorsal roots of the spinal cord changes, which leads to a decrease in pain.

The narrowing of the lumen of blood vessels prevents the development of edema, and the effect of thiamine is accompanied by pronounced analgesia. Unfortunately, the manufacturer did not provide data regarding the pharmacokinetics of the drug.

Indications and contraindications

Benalgin has the properties of non-steroidal anti-inflammatory drugs and also affects peripheral blood flow, so it can be used in neurology, traumatology, rheumatology and gynecology. The medication is also used after surgical interventions. Indications for taking Benalgin are:

• migraine, both classic and without aura;
• headache, tension;
• postoperative pain;
• radiculopathy;
• neuralgia;
• plexites;
• polyneuritis;
• dysmenorrhea;
• fever of any etiology;
• inflammatory and degenerative diseases of the musculoskeletal system.

Due to the large number of components, the drug has a wide list of contraindications:

• hypersensitivity to the components of the drug;
• bronchial asthma;
• anemia;
• leukopenia;
• thrombocytopenia;
• hepatic porphyria;
• uncontrolled arterial hypertension;
• decompensated renal/liver failure;
• sleep disturbance and excessive excitability;
• peptic ulcer of the stomach and duodenum;
• chronic bleeding.

The drug is contraindicated in children under 12 years of age, as well as throughout pregnancy and breastfeeding.

Instructions for use and special instructions

To use the product safely, it is important to read the detailed instructions for use and the rules of safe therapy.

Dosage

The initial dosage for Benalgin is 1 tablet 2-3 times a day for febrile syndrome. For chronic pain, it is recommended to take the drug 2 tablets 2-3 times a day. The daily dosage for adults is no more than 6 tablets.

Children from 12 to 16 years old are recommended to take half the adult dosage with the same frequency of administration, while the daily dose should not exceed 4 tablets. It is recommended to take Benalgin in the first half of the day.

When treating with Benalgin, a number of points must be taken into account:

1. Throughout the entire treatment period, the patient is advised to avoid products that contain caffeine - tea, coffee, as this can lead to an overdose.
2. Benalgin should not be used simultaneously with other NSAIDs, narcotic and non-narcotic analgesics, and MAO inhibitors.
3. Since the tablets contain starch, it is not recommended for people with gluten allergies. People who are prone to immediate allergic reactions should also take medications with caution.
4. Metamizole sodium can change the color of urine, but this is not accompanied by clinical pathology.
5. Benalgin should not be taken by athletes during competitions, as doping control may give a false positive result.

Possible side effects and overdose

The most common side effect from taking Benalgin is the development of allergic reactions of various types:

• anaphylactic shock;
• itching;
• Quincke's edema;
• bronchial asthma;
• hives;

With long-term use, there is a violation of the blood coagulation system, disturbance of sleep and the activity of heart rhythm drivers.

An overdose of Benalgin is accompanied by vomiting, nausea, mental agitation, pain in the epigastric region, tachycardia and even the development of convulsive syndrome.

At the first symptoms of an overdose, it is necessary to take the patient to the intensive care unit, rinse the stomach, prescribe sorbents, and ensure constant monitoring of the activity of the heart and respiratory system.

There is no specific antidote for Benalgin.

Similar means

Most often, instead of Benalgin, the following drugs are prescribed:

1. Aquacitramon is also a complex medicine that contains aspirin, caffeine and paracetamol. Unlike Benalgin, the drug has a stronger effect on liver cells, so it can increase the content of transaminases in the blood, which will affect the results of liver function tests. The presence of acetylsalicylic acid increases the risk of developing peptic ulcers and thrombocytopenia. The risk of developing aspirin-induced asthma also increases.
2. Coficil-Plus is a drug with a composition similar to Aquacitramon, but with a lower price. Coficil is a generic drug, and its pharmacological action is practically no different from the original formulas.

   The medication is contraindicated in children for the treatment of fever due to the development of Reye's syndrome, an encephalopathy with rapidly progressing liver failure. Therefore, you should not use Coficil-Plus if you have a fever caused by a viral pathology.

3. Solpadeine Fast - consists of two active ingredients - paracetamol and aspirin. Thanks to this, it is possible to avoid pathological effects on the mucous membrane of the gastrointestinal tract, as well as on the blood coagulation system. Solpadeine is also most effective in the treatment of fever and pain.

   The high price of Solpadeine is also justified by the dosage form. Soluble tablets are absorbed more quickly into the gastrointestinal tract and begin to have a therapeutic effect from the first minutes after administration.

   The drug should not be taken simultaneously with alcohol, as this enhances its hepatotoxic effect on liver cells.

   Solpadeine meets modern safety standards, therefore it is widely used among patients on prolonged therapy.

Sometimes taking multicomponent drugs is contraindicated due to a hyperreaction to its individual components. Therefore, to reduce body temperature, as well as eliminate inflammation of various etiologies, non-steroidal anti-inflammatory drugs are used as monotherapy.

Such drugs have a lower cost, but also less therapeutic activity. However, if there are risks when taking medications of this group, it is easier for the doctor and patient to monitor possible adverse reactions and make timely adjustments.

Reviews from doctors and patients

Patients and medical specialists note the high effectiveness of the drug in the fight against pain and fever:

Vladislava, 18 years old: “I purchased Benalgin by accident, simply as a means to relieve headaches. The pain went away within 10 minutes, which surprised me very much. After reading more about the indications for use, I decided to use it during menstruation to relieve pain. The effect was amazing.

It’s a pity, now they have stopped supplying it to the pharmacy, I hope the situation will change soon.” Maria, 30 years old: “I get headaches quite often. Sometimes I can just wait it out, but often I resort to taking medications.

In such situations, Benalgin became my “lifesaver” and quickly improved my condition. Now I use Aquacitramon, because of all Benalgin’s analogues, it’s the only one that suits me in terms of price/quality ratio.”

Vladlen, 37 years old, general practitioner, family doctor: “Benalgin has long been my favorite medicine. It was convenient to use for both adults and children over 12 years old. Very effectively and smoothly reduces body temperature, while eliminating headaches.

For inflammatory diseases of the musculoskeletal system, Benalgin also showed its best side. By properly collecting the patient’s life and illness history, any complications can be avoided.”

Benalgin has many advantages as an analgesic and pyrolytic, however, due to the fact that the drug may not be available in the pharmacy chain in the Russian Federation, the patient needs to check with the doctor or pharmacists about the availability of other similar drugs that will meet the necessary quality and safety parameters, as well as payment options patient.

Source: https://Pilyule.com/obzor/obezbolivayushhie/benalgin/

General information about the drug

The drug is produced by the Bulgarian pharmaceutical company Balkanpharma-Dupnitza, AD. It has analgesic and antipyretic properties, and also has an anti-inflammatory effect. INN – Metamizole sodium+Caffeine+Thiamine. Possessing a wide range of therapeutic effects, the drug is used in almost all medical fields.

Release forms and prices for the drug, average in Russia

To date, there is no information on the price of Benalgin in the pharmacy chain in the Russian Federation. In Ukraine, the drug is sold in the price category from 30 to 50 UAH. Below are the average prices for drug analogues that are available in the Russian Federation.

Benalgin tablets - instructions for use, analogues, composition, indications

Combined pain reliever.

Indications and dosage:

Symptomatic treatment of pain syndrome with:

• Migraines, tension headaches
• Inflammatory and degenerative diseases of the musculoskeletal system
• Postoperative conditions
• Diseases of the peripheral nervous system (radiculitis, plexitis, neuritis, neuralgia, polyneuritis, polyneuropathy)
• Dysmenorrhea

A single dose is equal to 1-2 tablets, the frequency of doses per day is from 2 to 3 times.

Overdose:

• Anxiety
• Nausea
• Oliguria
• Hypothermia
• Vomit
• Gastralgia
• Tachycardia
• Dyspnea
• Arrhythmia
• Impaired consciousness
• Liver failure
• Hemorrhagic syndrome

Treatment: symptomatic remedies, gastric lavage, saline laxative, forced diuresis, intake of enterosorbent (activated carbon), in case of severe poisoning - hemodialysis.

Side effects:

• Leukopenia
• Vomit
• Agranulocytosis
• Allergic reactions
• Tachycardia
• Sleep disturbance
• Arrhythmias
• Excitation
• Increased blood pressure
• Nausea

Contraindications:

• Hypersensitivity to drugs included in Benalgin
• Blood diseases
• Glaucoma
• Kidney failure
• Severe liver dysfunction
• Arterial hypertension
• Increased excitability
• Organic heart pathology
• Severe atherosclerosis
• Children's age up to 12 years
• Pregnancy and breastfeeding

Interaction with other drugs and alcohol:

The combination of Benalgin with other drugs requires special attention, because metamizole, which is part of the drug, is an enzyme inducer.

When used simultaneously with other antipyretic, analgesic and anti-inflammatory drugs, the risk of allergic reactions and side effects increases.

The combined use of Benalgin and drugs that suppress bone marrow function, there is a possibility of damage to white blood cells.

Neuroleptics and tranquilizers potentiate the analgesic effect of Benalgin.

Concomitant use with chlorpromazine may lead to hypothermia.

Some antidepressants, oral contraceptives, and allopurinol slow down the degradation of metamizole and thus may increase the toxicity of Benalgin.

The drug reduces the concentration of cyclosporine A in the blood, so it may be unsafe in the presence of transplants.

Concomitant use with sympathomimetics can lead to central nervous system stimulation.