Grammidin with anesthetic spray for local use dosage 112 doses

Sore throat. Which Grammidin to choose?

Winter is a time of cold weather, and with it an epidemic of colds. During ARVI, the throat is the first to take the blow of infection, because it is in the throat that protective lymphoid structures - tonsils - are concentrated. They try to trap viruses and bacteria that enter the air and prevent them from passing further into the respiratory tract. An emerging sore throat is an SOS signal – the body needs help. Let's figure out what medications for sore throat are best to use during this period?

Causes of a sore throat

Most often, a sore throat is the result of:

• acute inflammation of the tonsils, which is also called tonsillitis or acute tonsillitis;
• exacerbation of chronic tonsillitis;
• inflammation of the pharyngeal mucosa (pharyngitis).

The most common causative agents of colds are viruses and bacteria (staphylococci, streptococci, pneumococci, anaerobic bacteria). The likelihood of infection by pathogenic microorganisms increases in conditions of reduced immunity, to which concomitant chronic pathologies, hypothermia, and an unbalanced diet low in vitamins predispose. It is especially difficult for residents of large cities, since with a large number of people it is difficult to avoid contact with an infected person.

That is why, during periods of cold weather and epidemics of colds, it is necessary to be prepared for quick response measures and keep the best medicine for a sore throat on hand.

Grammidin for the treatment of throat

So, it is clear that the throat hurts during the cold season due to infectious inflammation. The severity of the pain syndrome may vary. In some cases, it is a moderate pain that appears only when swallowing, and in others it is intense, painful, and does not stop for a minute.

Taking into account the different degrees of pain syndrome, medications (drugs) for throat disease should be chosen differentially.

Grammidin for throat is available in four different versions:

• Grammidin Neo. This product contains the antibiotic gramicidin C and the antiseptic cetylpyridinium chloride in an optimal dose for adults. Grammidin Neo is available in a package with a green scarf.
• Grammidin Neo with anesthetic (packaging with a red scarf). Additionally contains the local anesthetic oxybuprocaine.
• Grammidin for children (packaging with a yellow scarf). This is an antibiotic with an antiseptic in a dosage ideal for children.
• Grammidin spray - contains an antibiotic in combination with an antiseptic in a dosage form that allows you to treat “hard-to-reach places” of the throat.

Which Grammidin to choose if you have a sore throat?

For moderately severe sore throat and sore throat, adult patients should pay attention to Grammidin Neo (green scarf).

Children aged 4 to 12 years are recommended to take Grammidin in a children's dosage (yellow scarf), especially if the child prefers the taste of raspberries.

Grammidin with an anesthetic (in a package with a red scarf) will help cope with intense sore throat, which causes severe discomfort. For this purpose, it is also suitable for children starting from 4 years of age.

Spray Grammidin has the same properties as Grammidin Neo, it is suitable for those who prefer sprays to tablets and love the effect of “irrigating” the throat.

Grammidin Neo

Packaged with green scarf

• Lozenges

The unique composition of the drug includes two active components: an antibiotic - gramicidin C, effective against common pathogens of infectious diseases of the pharynx (streptococci, staphylococci, pneumococci and anaerobic bacteria) and an antiseptic - cetylpyridinium chloride, which suppresses the growth and reproduction of pathogens of infectious diseases of the oral cavity.

The drug has an antimicrobial effect, reduces inflammation, and makes swallowing easier.

Grammidin neo lozenges are used 1 tablet 3-4 times a day for adults and children over 12 years old and 1 tablet 1-2 times a day for children 4-12 years old.

• Grammidin spray

Packaged with green scarf

Like Grammidin Neo, it contains gramicidin C and cetylpyridinium chloride.

The spray is used topically by spraying onto the mucous membrane of the mouth and throat. Used after meals. Dosage for adults: 4 injections per application 3 times a day for 7 days. Immediately after using the drug, you should refrain from eating and drinking for 1 hour.

The product in the form of a spray is approved for use from the age of 18 years.

special instructions

The drug should not be used if there are open wounds in the oral cavity, since cetylpyridinium chloride slows down wound healing.

The drug contains ethanol. In the maximum single dose of the drug, the ethanol content is up to 0.08 g.

The drug does not affect the ability to perform potentially hazardous activities that require special attention and speed of reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator, etc.).

Grammidin Neo with anesthetic

Packaged with a red scarf

• Lozenges

Grammidin with anesthetic is a medicine for severe sore throat, because it contains a local anesthetic - oxybuprocaine. Many patients are interested in: “Which Grammidin is stronger?” Differences in the line of drugs concern only the severity of the analgesic effect. In Grammidin with an anesthetic it is maximum, while the product retains the adult dosage of the antibiotic Gramicidin C (3.20 mg) and the antiseptic cetylpyridinium chloride (1.05 mg).

Grammidin with an anesthetic is perhaps the best drug for severe sore throat. The anesthetic oxybuprocaine quickly and reliably blocks sensitive nerve endings, so painful sensations in the throat will not bother you for a long time. At the same time, Grammidin with an anesthetic also has an antimicrobial effect, affecting the immediate cause of throat diseases.

Grammidin Neo with anesthetic is available in lozenges.

Adults and children over 12 years of age are recommended to take the drug 1 tablet 3-4 times a day.

For children from 4 to 12 years old, the frequency of administration should be reduced to 1-2 times a day, but also take 1 tablet.

Drug interactions

This medication does not have a negative effect on the human psyche, therefore it is allowed to use the drug while driving a car or while performing work that requires high psychomotor reactions.

At the moment, episodes of drug interactions between the drug and other groups of drugs are not provided. However, the spray should not be combined with other antimicrobial or anti-inflammatory agents of local or systemic action.

When prescribing the drug while using other medications, it is recommended to inform the treating specialist.

Grammidin Children's

Packaged with a yellow scarf

• Lozenges

Which Grammidin is best to give to a child? Especially for children who are bothered by a sore throat, there is Grammidin for children. It contains the antibiotic gramicidin C in a reduced dosage, as well as a dose of the antiseptic cetylperidinium chloride that is safe for the baby’s body.

The drug is approved for use from 4 years of age.

For sore throat, 1 lozenge is prescribed 4 times a day.

If your throat hurts, Grammidin comes to the rescue. The drug is well tolerated and not only improves well-being, but also eliminates the cause of inflammation, promoting a speedy recovery. Whatever Grammidin you choose, your throat will tell you - Thank you!

Sore throat is an unpleasant symptom of many diseases of the oropharynx. The choice of drug to treat and eliminate the complaint is based on the causative agent, the patient’s age, the presence of concomitant diseases, financial capabilities and contraindications. The taste of the medicine, ease of use, effectiveness, confirmation of safety and availability in the nearest pharmacies are also important.

The drugs of choice are the Grammidin line. Release form for every taste. The disadvantage is the high cost of the drugs, from 270 rubles per pack.

When choosing cheap analogues of Grammidin, important criteria are composition, safety, safety of use in children, effectiveness and availability.

Indications for use of Grammidin

Grammidin tablets and spray are prescribed for:

• pharyngitis;
• sore throat;
• tonsillitis;
• sore throat, rawness, soreness, pain when swallowing.

The drugs are freely sold from pharmacies. Children's tablet form is allowed from 4 years, spray - from 6 years.

The regular drug can also be used from 4 years of age, the dosage regimen is different. Before purchasing and using, you must read the instructions for use.

Overdose

If dosing rules are violated, negative symptoms may develop.

Signs of overdose:

• nausea and vomiting;

  

• development of diarrhea;
• other dyspeptic or gastrointestinal disorders.

If symptoms of overdose occur, you should stop taking the medication and consult a specialist. In some cases, it is possible to prescribe sorbent drugs or perform gastric lavage.

Grammidin - instructions for use

Lozenges are used after meals, the dosage depends on the chosen form and the age of the patient. For adults, 3-4 times a day is optimal.

The spray is sprayed onto the mucous membranes of the mouth and throat three times a day. There are 4 injections per application.

The maximum course of use of the drug is up to 7 days.

The effectiveness of treatment is influenced by how to use Grammidin - before or after meals. It is correct to dissolve or spray the medicine after eating and then do not eat or drink for an hour. This ensures that the components remain on the inflamed area of ​​the oropharynx for a long time and have a strong effect.

"GRAMMIDIN" - lozenges: reviews

My throat hurt. They recommended Grammidin to me, and it helped me a lot. It took exactly one pack to cure my throat. I took a tablet three times a day. At the same time, the tablets themselves are tasty and at the time of use after resorption, they alleviate pain for several hours. Now, whenever my throat starts to hurt, I take these pills.

I found out about Grammidin lozenges from reviews on the “mother’s” forum. I decided to try it... Yes, they are tasty and cool, but it didn’t give me any effect. At the same time, I want to say that I also gargled and sprayed a spray into my throat. Perhaps they all do not work together, although I paused between them for more than half an hour. As soon as cold symptoms appeared - a sore or sore throat - I was given these tablets. Even if you kill me, it doesn’t help! I think that everything is individual, including in this matter. Only the old grandfather's methods with onions, garlic and inhalations with potatoes help me. I would give the drug 2 out of 5 just for taste.

Grammidin's analogs

Pharmacies offer three types of the drug - the usual one with a green scarf, with a yellow scarf for children and with a red scarf for severe sore throat.

Substitutes for Grammidin differ in composition, effect and release form, age restrictions, i.e., the ability to use them for the treatment of children, pregnant and lactating women. There are sprays and lozenges, drops and tablets for oral administration.

List of cheap analogues of Grammidin

Hexalize

Manufacturer: Bouchard-Recordati Laboratories, France

Release form: lozenges

Active ingredients: lysozyme hydrochloride, biclotymol, enoxolone

An analogue of Grammidin tablets is the French drug Hexalize with a combined composition. Has several therapeutic effects:

• antiseptic;
• antiviral;
• anti-inflammatory;
• local anesthetic.

The analogue of Grammidin Hexaliz is used for infections and inflammation of the oropharynx in adults and children over 6 years of age. You do not need a prescription to purchase the medicine.

Gramicidin S

Manufacturer: Update, Russia

Release form: lozenges

Active ingredient: gramicidin C

The analogue of Grammidin in Russia is the domestic medicine Gramicidin S. It contains the same local antibacterial component. The difference is that the Russian analogue does not contain antiseptics or anesthetics.

Anti-angina

Manufacturer: Natur product, Switzerland or the Netherlands

Release form: tablets and lozenges, spray

Active ingredient: chlorhexidine, ascorbic acid, tetracaine

An analogue of Grammidin with an anesthetic – Anti-angin for resorption and irrigation of the oropharyngeal mucosa. Has similar properties:

• fights infection and inflammation in the oropharynx;
• facilitates swallowing and eliminates pain;
• increases local immunity and the body's resistance to negative factors.

The cost of the analogue is up to two times lower.

Ingalipt

Manufacturer: Pharmstandard, Esko-pharm, Altaivitamins, Russia

Release form: aerosol, spray

Active ingredients: peppermint leaf oil, sulfanilamide, thymol, eucalyptus leaf oil

The drug Ingalipt is a well-known domestic analogue of Grammidin at a more affordable price. Fights infection (bacteria, fungi), reduces inflammation, and has a mild analgesic effect. It has a specific smell and taste. Age restrictions vary by manufacturer.

Imudon

Manufacturer: Pharmstandard, Russia

Release form: lozenges

Active ingredient: bacterial lysates

Imudon – lozenges for children over 3 years of age based on bacterial lysates. The mechanism of action is the activation of local immunity to fight the pathogen and eliminate inflammation and sore throat. The drug has no analogues in composition and mechanism of action; it eliminates the cause of oropharyngeal diseases, and not just the symptoms.

Septolete Total

Manufacturer: KRKA, Slovenia

Release form: lozenges, spray

Active ingredient: benzydiamine, cetylpyridinium chloride

The drug Septolete Total is a combined analog containing an antiseptic and an NSAID. Used to relieve sore throat in children over 6 years of age and adults.

If there is an intolerance to the antiseptic, you can use drugs based on NSAIDs (non-steroidal anti-inflammatory drugs): Tantum verde, Vertum lor, Angidak sept, Zvezdochka lor, etc. Sprays are allowed during pregnancy and breastfeeding, for the treatment of children from 3 years of age. Lozenges are used from the age of 6 years.

Other analogues:

• Tonsilgon - tablets and drops for oral administration with antiseptic, anti-inflammatory properties.
• Miramistin is a safe antiseptic in the form of a solution and spray, used in pediatrics and otolaryngology from scratch.
• Laripront - lozenges containing lysozyme and dequalinium chloride, components that fight microorganisms that cause ENT diseases.
• Trachisan is a Ukrainian analogue with antimicrobial and anesthetic effects.
• Bioparox is currently discontinued due to unsafety.
• Homeovox is a homeopathic remedy for the treatment of hoarseness and laryngitis.
• Theraflu lar - spray and lozenges with analgesic and antiseptic effects, forms are used for sore throat, sore throat, inflammation.
• Sebidine is a lozenge containing an antiseptic (chlorhexidine) and ascorbic acid to improve local immunity.
• Rengalin is a domestic remedy with antitussive and anti-inflammatory effects, available in solution and lozenges, based on antibodies.

Analogs differ in composition, mechanism of action, indications, contraindications, and age restrictions.

Grammidin or Lizobakt - which is better?

Manufacturer: Bosnalek, Bosnia and Herzegovina

Release form: lozenges

Active ingredient: lysozyme, pyridoxine

For children over 3 years of age, pregnant and lactating women, Grammidin can be replaced with Lizobact lozenges. The analogue contains lysozyme, a component with an antimicrobial effect, effective against bacterial and fungal viruses. Advantages: no negative impact on the microflora of the oral cavity.

Another component of Lysobact is Pyridoxine. This vitamin promotes mucosal protection and healing.

Indications for use of the analogue are diseases of the oral cavity of an infectious and inflammatory nature.

Thus, Lizobakt is a cheaper analogue of Grammidin for children and adults with an antiseptic effect.

Grammidin contains a local antibiotic and antiseptic that provide a strong antimicrobial effect. Used for treatment from 4 years of age in children and adults.

The main difference is the composition and restrictions. The Grammidin analog Lyzobakt contains lysozyme, which is found in human saliva. It is safe and is prescribed to children over 3 years of age, pregnant and lactating women. Grammidin is not used during pregnancy and breastfeeding.

Grammidin for children and adults is prescribed for serious inflammation of the oropharynx. It is more effective and has a broad spectrum antibacterial effect. Lizobact is safer.

Grammidin or Faringosept

Manufacturer: S.K. Therapy S.A., Romania

Release form: lozenges

Active ingredient: ambazon

Faringosept is an analogue of adult Grammidin for the throat, and can also be used for children from 3 years of age. Belongs to the group of antiseptic agents.

Grammidin has a wider spectrum of antibacterial action due to the content of a local antibiotic and antiseptic. The disadvantage is the high cost and lack of various tastes, the possibility of use in children from 4 years of age. The regular and anesthetic ones have a mint taste, the children's form has a raspberry taste.

The analogue of Grammidin Faringosept is cheaper and is available in tablets of several flavors:

• classic (chocolate);
• lemon;
• honey-lemon;
• cinnamon;
• mint.

Faringosept is used in children aged 3 to 4 years and older with mild sore throat and inflammation. Grammidin is stronger and is used for severe pain and inflammation. There is a form of Grammidin children's spray.

Pharmacodynamics and pharmacokinetics

The drug is a combination drug used in the treatment of infectious and inflammatory processes occurring in the throat and mouth. The active component (gramicidin C) helps to increase the permeability of the protective barrier of bacterial cell membranes, which leads to a gradual breakdown of its stability and, as a result, causes the death of the bacterium.

The second active ingredient (cetylpyridinium) has high antiseptic properties, suppresses the activity of pathogens, while reducing the clinical manifestations of the disease.

The combined effect of the drug is aimed at reducing inflammatory reactions, eliminating discomfort in the throat, and helping to eliminate pain in the throat when swallowing. This medication is indicated for topical use, so its components are practically not absorbed and do not exhibit pharmacokinetic properties.

Grammidin or Strepsils - which is better?

Manufacturer: Reckitt Benckiser, UK

Release form: lozenges

Active ingredient: amylmetacresol, dichlorobenzyl alcohol

Synonyms: Hexoral tabs, Adjisept, Suprimalor, Gorpils, etc.

An analogue of Grammidin for children and adults is the wide range of Strepsils. These are lozenges of different flavors:

• for children without sugar – strawberries and lemon;
• honey and lemon;
• menthol and eucalyptus;
• lemon without sugar.

There is also a warming formula with vitamin C and Intensive. The latest Strepsils contains a different active ingredient - flurbiprofen - to eliminate sore throat, swelling of the mucous membrane and discomfort.

Differences between Grammidin and Strepsils:

• an analogue with menthol and eucalyptus additionally facilitates breathing with concomitant runny nose and nasal congestion.
• Strepsils is a wide range of lozenges, there is also a spray. Grammidin has similar release forms.
• a wide variety of Strepsils flavors, especially if you are allergic to additional components, dyes and preservatives.
• Grammidin is used from 4 years of age and is more effective, the analogue is used from 6 years of age.
• the cost of Strepsils is lower.

Both throat medications – Grammidin and Strepsils – have been present on the pharmaceutical market for a long time and have established themselves among buyers and doctors. The choice of an analogue depends on the symptoms, the desired effect and taste of the medicine, the patient’s age, and financial capabilities. You can replace Grammidin for a child with Strepsils if there are no contraindications.

Dorithricin or Grammidin - which is better?

Manufacturer: Medice Arzneimittel, Germany

Release form: lozenges

Active ingredient: tyrothricin, benzalkonium chloride, benzocaine

You can replace Grammidin with anesthetic with the imported drug Dorithricin. This is a combination remedy with the following medicinal properties:

• antiseptic;
• local anesthetic, i.e. eliminates sensitivity of nerve endings, swelling of the throat mucosa, sore throat and irritation;
• local antibacterial.

The drug is used from 6 years to 6 times a day.

Grammidin with anesthetic and the analog Dorithricin have similar effects; there are no studies on which is better for pharyngitis and other throat diseases. They differ in composition, mechanism and price. Grammidin is available in tablets (16 pieces) and spray for hard-to-reach areas of the oropharynx. Analog – 10 tablets per package, the cost of the course is higher.

Grammidin or Hexoral - which is better?

Manufacturer: Famar Orleans, France

Release form: aerosol, solution

Active ingredient: hexethidine

Synonyms: Maxicold ENT, Stopangin, Hexetidine, Gelangin Nova, etc.

An analogue of the Grammidin spray is the advertised and well-known drug Hexoral in the form of an aerosol; a solution for rinsing the oropharynx is less commonly prescribed. This is an original antimicrobial agent, active against bacteria, fungi, and some viruses. Used to treat children from 3 years of age, can be used by pregnant and lactating women.

The advantage of Hexoral is that it has a spray form with 4 nozzles, which is suitable for a large family or several children.

Differences between analogues:

• release form - Hexoral aerosol and Grammidin spray.
• Grammidin is additionally available in the form of lozenges.
• different composition - the analogue contains hexetidine, Grammidine is a combined drug based on a local antibiotic and antiseptic.
• Grammidin is allowed from 4 years of age, and its analogue from 3 years of age.
• Possibility of use for the treatment of pregnant and lactating women - only Hexoral.

The cost of analogues is approximately the same. Both have a local antiseptic effect and are used in pediatrics and adult practice for diseases of the oropharynx.

"GRAMMIDIN": composition

For Grammidin tablets, the price is determined not only by market factors, but also by its composition, which includes:

1. Active ingredient:

• gramicidin S (gramicidin S) is a polypeptide substance from the group of antibiotics that has antimicrobial and antiseptic effects;

1. Additional substances:

• emulsifier calcium stearate;
• food sweeteners and sweeteners – lactose and sucrose;
• Methylcellulose is an essential substance based on methanol and cellulose that acts as a thickener.

Sold in the form of flat white tablets weighing 3 milligrams in slips of 10 pieces, 2 slips in a cardboard box.

Grammidin Neo analogues

Manufacturer: Famar, Netherlands or Valenta, Russia

Release form: lozenges, spray

Active ingredient: gramicidin C, cetylpyridinium chloride, oxybuprocaine

The drug Grammidin Neo - tablets with or without anesthetic. Grammidin - throat spray.

The analogues of the drug are the same as those of Grammidin spray:

• Lysobacter;
• Strepsils, Strepsils Intensive;
• Dorithricin;
• Stopangin;
• Anti-angina;
• Hexalize et al.

What to choose - Grammidin or Grammidin Neo, depends on preferences. Some patients choose tablets, others choose a spray for the throat and treatment of hard-to-reach areas.

Composition of the drug

The active ingredients of the drug are gramicidin C and cetylpyridinium chloride.

Composition of auxiliary components:

• 0.019 g ethanol solution;
• 0.2 mg trichlorogalactosucrose;
• 0.82 mg mint flavored supplement;
• 33 mg glycerol;
• 0.058 mg citric acid extract;
• 0.022 mg sodium citric acid;
• 0.4 mg emulsifier TWIN (polysorbate 80);
• 0.184 mg methylparaben;
• 0.02 mg propylaparaben;
• no more than 0.2 ml of filtered water.

  
  Grammidin spray

The solution is poured into aluminum bottles equipped with a special dispenser. Each bottle is packed in a cardboard container and is accompanied by an insert.

Answers on questions

1. What is better – Grammidin spray or tablets?
   Spray and tablets have the same composition. The first form is preferable for treating hard-to-reach areas three times a day. Tablets – up to 4 times a day.
2. Which is better Grammidin - red or green?
   The packaging of the Grammidin line is clearly designed: with a green scarf, it contains an antiseptic and antibiotic, used for moderate sore throat. With a red scarf, it contains an anesthetic. This form is used for severe sore throat, as it blocks sensitive nerve endings. Red Grammidin is stronger and more expensive. What to choose depends on the intensity of the pain syndrome.
3. Can Grammidin be used by pregnant women or not?
   Grammidin is not used during pregnancy and breastfeeding. If pain occurs in patients from this group, you should consult a doctor and choose safe analogues (rinsing with soda, sea salt or water, furatsilin, sucking Lizobact tablets).

Price

This medicine has different prices, which depend on the area of ​​​​sales. The price is also affected by the retail pharmacy chain that sells the drug.

You can purchase a pharmacological drug at any specialized medical institution or pharmacy located at your place of residence.

Before using the spray, it is recommended to consult a doctor or pharmacist, and also carefully study the instructions for using Grammidin. Additionally, it is recommended to read reviews from doctors and parents who have used the drug in therapy in children.