Composition of the drug Bisakidol and how long does it take to act?

Published 03/02/2019 · Comments: · Reading time: 6 min · Views: Post Views: 15,992

According to statistics, every third adult in Russia suffers from the problem of stool retention. Constipation is also common among children. Malaise occurs for many reasons, the elimination of which may take time. At the same time, I want to solve the problem quickly and delicately. “Bisacodyl” suppositories are one of the most well-known drugs for eliminating situational constipation. The product is effective and inexpensive.

Composition and release form

The main component of the drug is bicasodil. Excipients have different compositions depending on the dosage form. These are cellulose, lactose, powdered sugar, talc, wax, magnesium stearate, medical polyvinylporrolidone, corn starch.

The laxative is dispensed in the form of:

  1. Tablets - have a soluble intestinal coating, for oral administration. Light brown, biconvex, round in shape. The package contains several blisters of 10 pieces.
  2. Suppositories are administered rectally. Contains 10 mg of active substance. Packaged in cardboard packaging of 10 suppositories.

Overdose

The use of Bisacodyl in high doses can lead to diarrhea, abdominal cramps and clinically significant loss of potassium and electrolytes. Sometimes intestinal atony and congestive inflammation of the rectum may occur.

Long-term use of laxatives can cause chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism and nephrolithiasis. As a consequence of hypokalemia, cases of renal tubular damage, metabolic alkalosis, and muscle weakness have been reported.

Treatment:

fluid replacement therapy and correction of electrolyte imbalances (especially hypokalemia).

How does the laxative Bisacodyl work?

Bicasodil is a strong drug. The main pharmacological effect is laxative. It has a direct effect on the nerve receptors of the large intestine, helping to restore peristalsis and its natural release. The drug stimulates the synthesis of mucus, so emptying the body occurs easily.

Along with the normalization of intestinal motor function, Bicasodil accumulates fluid in it. Due to this, the feces soften and are excreted without problems.

After oral administration, the therapeutic effect of the laxative is observed after 6 hours. When using a suppository, the effect occurs after 30-60 minutes.

What to choose?

There are many remedies for treating constipation. Some people will prefer to do an enema, while others find it easier to take pills or syrup. Each method has advantages and disadvantages.

Candle tablets and enema

An enema does not have a general effect on the body and acts quickly, but many will find the procedure complicated and unpleasant. This will most often require an assistant; not everyone can do it on their own.

The effect of using internal remedies develops from 5 to 12 hours. In addition, when absorbed in the digestive tract, oral medications inevitably have a systemic effect on the body. It may be insignificant; many modern drugs have virtually no it. However, the risk of developing unwanted side effects is always higher when taking the medicine orally.

Suppositories are either completely or practically not absorbed and have no general effect. At the same time, they are easy to use and do not require an assistant, as with an enema. The effect occurs within 10 - 15 minutes. Guided by these advantages, many choose candles to combat situational constipation.

Contraindications

Absolute contraindications for the use of laxatives are:

  1. Children under 2 years of age.
  2. Allergic reaction to active or auxiliary components.
  3. Violation of the integrity of the anus.
  4. Severe gastrointestinal diseases.
  5. Inflammation of the anterior abdominal wall.
  6. Hernia.
  7. Spastic constipation.
  8. Intestinal neoplasms.
  9. Pain in the epigastric region of unknown etiology.
  10. Inflammatory lesion of the caecum.
  11. Gynecological bleeding.
  12. Cystitis.
  13. Dehydration of the body.
  14. Violation of water balance.
  15. Blood loss from the gastrointestinal tract.

It is also not recommended to use the drug during pregnancy, lactation, liver and kidney diseases.

Indications for the use of suppositories

The main purpose of the medicine is to relieve constipation, which causes hardening of stool, making defecation difficult. This disruption of intestinal activity may accompany the following diseases:

How to take the laxative Bisacodyl

Depending on the dosage form, Bicasodil has features in its use.

Suppositories are intended for administration into the colon. The dose of the drug is 10-20 mg per day. For the first dose, no more than 1 suppository per day. If there is no therapeutic effect, the dosage is doubled.

To empty the intestines, the suppository is administered at any time, the effect occurs within an hour. The pharmacological activity of the laxative does not depend on food intake.

To cleanse the body before medical procedures, you need to take 2-4 tablets one time in the evening and insert 1 suppository into the anus in the morning.

The dose for children over 12 years of age and adults is 1-3 tablets or 5-15 mg per day. It is advisable to take 1 tablet before bedtime. If there is no laxative effect, double doses of the drug are used.

The pills are taken regardless of food, at a convenient time. The therapeutic effect occurs after 6 hours. The first dose of Bisacodyl should be started with a minimum dose of 5 mg per day. Subsequently increase to 10-15 mg if necessary.

To prevent overdose, do not take more than 4 tablets per day.

Do not chew dragees and tablets; take them with plenty of water. When using the drug, it is recommended to monitor the liquid you drink during the day, at least 1.5 liters.

The course of therapy with Bicasodil is a week. If it is necessary to use the drug for a long time, take a break.

If the activity of the excretory system is disrupted and there is liver pathology, the drug should be taken with caution. Dosage per day is no more than 1 tablet.

During the treatment course, it is important to exclude dairy products and mineral water from the diet. They contribute to the rapid dissolution of the drug, which leads to a lack of therapeutic effect.

Application

Instructions for use are simple.

  1. Due to the quick effect, it is necessary to use candles at home, in a comfortable environment. This product is not suitable for use on the road or at work.

how to place suppositories rectally

  • Before and after setting the candle, you should wash your hands thoroughly.
  • The package contains 10 suppositories in polymer blisters of 5 pieces. One candle can be easily separated from the blister along the punched dotted line. Many people mistakenly try to cut the suppository out of the cell with scissors. This is of no use. You just need to pull the “tendrils” of the package in opposite directions from the pointed tip of the candle. To prevent your hands from slipping on the polymer, they must be dry.
  • To place a suppository, it is better to lie on your left side, bending your knees and slightly pulling them towards your stomach. This is explained by the anatomical location of the intestines in the abdominal cavity and will ensure the greatest effectiveness of the drug.
  • There is no need to place the suppository very deeply. During insertion, a person will feel when the muscular ring of the anus (sphincter) closes behind the candle. This is enough to prevent it from falling out and to have its effect.
  • The sensation of a foreign body in the rectum may immediately make you want to run to the toilet, but you shouldn’t do that. In order for the candle to completely melt and the effect of the drug to fully develop, you need to lie quietly for 10 - 15 minutes.

Side effects

A laxative can cause negative reactions such as:

  1. Gas formation.
  2. Pain in the epigastrium.
  3. Feeling nauseous.
  4. Possible vomiting.
  5. Diarrhea, including the profuse type, which leads to dehydration.
  6. Lack of intestinal motility.
  7. Allergic manifestations in the form of swelling, itching, development of urticaria symptoms.
  8. Local irritation in the anus when taking suppositories.

"Bisacodyl" suppositories during pregnancy

Preventing constipation during pregnancy

The instructions allow for careful use in pregnant women. It should be remembered that stimulation of the intestines can cause unpleasant spasms, seething, and pain. For this reason, it is advisable for pregnant women to prefer Glycelax or Glycerin suppositories with a milder effect.

The substance bisacodyl is not absorbed in the intestine. This is a plus for nursing mothers, since it will not pass into breast milk and will not have an effect on the baby. However, it is better for this category of patients not to self-medicate, but to seek advice from a specialist.

Patient reviews about treatment

Most patients respond positively to Bisacodyl suppositories. High efficiency and rapid action of the drug are noted.

After the operation, I spent a long time in a supine position. After three, I asked for an enema, but the doctor suggested Bisacodyl suppositories. Within two hours I was able to go to the toilet without any problems.

Elena

Irregular eating leads to problems with intestinal function. I use laxative suppositories. The effect of the drug occurs very quickly, but sometimes there is a cutting pain in the lower abdomen, which goes away after cleansing the intestines.

Irina

I used laxative suppositories after taking antibiotics, since kefir and vegetable salads did not help.
I take the medicine in the morning. The effect comes very quickly. The dosage must be strictly observed and not used too often. Valentina

Analogs and synonyms of suppositories

Drug manufacturers offer a wide selection of analogues and synonyms of Bisacodyl suppositories.

Synonyms are medicines containing bisacodyl as an active substance. Analogues have a similar effect, but contain other active ingredients.

The following drugs have a similar effect: Bisacodyl-Altpharm suppositories, Apo-Bisacodyl tablets, Bisacodyl-Hemofarm tablets, Dulcolax, Laxacodil, Laxatin, Pirilax, Stadilax.

Glycerin suppositories have a safe and gentle effect, which are used to treat hemorrhoids and relieve bowel movements in young children.

If the patient needs to choose which laxative works immediately, it is better to find out from the attending physician, he will also help determine which remedy is right for you.

You can buy medications at a pharmacy without a doctor's prescription.

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