Instructions for use of the drug Debridat (analogue of Tribux) capsules 150 mg No. 20

Indications for use

Main indications of the drug Debridat:

• pain in the abdomen and pelvis;
• pain localized in the upper and lower abdomen;
• constipation;
• functional diarrhea;
• diseases of the esophagus, digestive organs, peritoneum, duodenum, stomach, pancreas, biliary tract, gall bladder;
• flatulence and similar conditions;
• enteritis (the process of inflammation of the small intestine);
• non-infectious colitis (inflammatory process regarding the inner layer of the large intestine);
• unspecified colitis and non-infectious gastroenteritis (inflammatory damage to the intestines and stomach);
• diarrhea and gastroenteritis of approximately infectious etiology;
• symptoms and signs that usually appear in diseases of the abdominal cavity and digestive system;
• other diseases of the digestive and intestinal organs;
• unspecified pain in the abdominal area;
• other functional intestinal disorders.

Debridet, to summarize, is indicated for the treatment of polymorphic symptoms of gastroenterological diseases related to irritable bowel syndrome and functional gastrointestinal diseases, with symptoms of intestinal spasms, flatulence, pain and colic in the abdominal cavity, diarrhea, and constipation.

Debridet is also successfully used as a therapeutic agent when preparing a patient for gastrointestinal endoscopy or x-ray in case of paralytic intestinal obstruction.

Contraindications

Debridat is one of the few medicines that have virtually no side effects and do not cause serious complications. It is for this reason that it can be prescribed to almost all categories of people.

Contraindications to the use of Debridat, according to the instructions, is hypersensitivity to its active substance or any of the auxiliary ingredients.

It is also not recommended to take Debridat during pregnancy and breastfeeding (this is due to the lack of clinical data confirming its safety).

Since Debridat contains sugar, people suffering from diabetes should take its presence into account in order to correctly calculate the sugar load on their body.

Release form and composition

Available in the following forms:

• Suspension for oral administration. Sold in 250 ml bottles.
• Powder for the preparation of a solution for oral use, sold in bottles.
• Tablets: sold in blisters of 10 pieces. There are 2 blisters in a cardboard pack.

Description

Debridat suspension (DEBRIDAT) is a modern drug that has the property of regulating intestinal motility. It relieves spasms of smooth muscles and works exactly as needed in each specific case: for constipation, it has a relaxing effect, and for weak motor skills, on the contrary, it stimulates peristalsis.

Debridet suspension is used for functional disorders of the gastrointestinal tract, as well as in preparation for endoscopic examinations and operations.

Italian pharmacists produce Debridat in powder form for the preparation of a suspension, since the finished suspension has a very short shelf life. This dosage form of the drug has proven itself well because it is easy to use and allows you to accurately dose the drug in the right quantities for both children of any age (starting from infancy) and adults; Its orange flavor will appeal to kids who will happily take the medicine.

To obtain a suspension, add water to the powder until a volume of 250 ml is obtained (a special mark is indicated on the bottle) and shake thoroughly. After adding water, store the prepared suspension in the refrigerator for no more than 3 weeks.

Active substance: trimebutine 72 mg/15 ml (1 tablespoon).

Additional substances: sodium methyl benzoate, orange flavor, sucrose.

Indications

The drug is produced in the form of 100 mg tablets and powder for suspension. Taking the drug is indicated for the following pathologies:

1. for pain syndromes in the gastric region and hip area,
2. for diseases of the digestive organs,
3. with congestion in the biliary tract, which causes constipation,
4. when suffering from diarrhea and flatulence,
5. with inflammation in the digestive tract.

The drug Debridat in tablet form is intended for adult patients. The drug is taken in a dosage of 1 or 2 tablets up to three times a day, depending on the severity of the disease.

The dosage of Debridet suspension is indicated in the instructions for use. It should be 2 tablespoons. It is recommended to take the drug 3 times throughout the day.

The children's dosage of the drug depends on the age of the baby. For six-month-old children, the suspension is prescribed half a teaspoon. Infants from 6 months to 1 year are given 1 teaspoon. Children from 1 year to 5 years are prescribed to take 1 teaspoon 3 times a day. For children over 5 years of age, it is recommended to increase the dose of the drug to 3 teaspoons three times a day. The suspension is available in orange flavor, so all kids like it.

Before use, Debridate in the bottle must be shaken. The suspension is stored in a cold place at temperatures not lower than 8 degrees. The diluted drug can be used for no more than 20 days.

Pharmacological action of Debridat

The mechanism of constipation is based on dysfunction of intestinal smooth muscles, changes in peristaltic contractions, both towards spasm and towards worsening intestinal motility. Both of these conditions can be caused by:

• Intestinal diseases associated with dysfunction;
• Tumors in the intestine;
• Lack of urge to defecate;
• Overdistension of the intestines, caused by frequent refusals to go to the toilet and, as a consequence of this, excessive accumulation of feces in it;
• Frequent stress that prevents regular bowel movements;
• Sedentary lifestyle and low physical activity of a person;
• Tumors that are localized in the abdominal cavity and put pressure on the intestines, disrupting its peristalsis;
• Vascular pathologies that lead to malnutrition of the intestinal walls.

Each of the above conditions can become a prerequisite for spastic contraction of one or another part of the intestine, or, conversely, its complete relaxation.

Trimebutine, which is part of Debridat, stimulates the smooth muscles of the intestine in hypokinetic conditions and acts as an antispasmodic in hyperkinetic conditions. Its action extends to the entire length of the gastrointestinal tract. Therefore, Debridat, reviews of doctors and patients who have taken this drug confirm this, it allows you to reduce the pressure of the esophageal sphincter, stimulates the process of gastric emptying, helps to enhance intestinal peristalsis, as well as the response of the muscle fibers of the colon to certain food irritants. In addition, taking Debridat:

• Helps normalize bowel movements and make them regular;
• Eliminates the feeling of discomfort and pain in the abdomen;
• Allows you to get rid of the accumulation of gases in the stomach and eliminates the unpleasant symptoms of flatulence;
• Eliminates dyspeptic symptoms;
• Relieves nausea and vomiting.

Violation of peristalsis of the esophagus, stomach and intestines, which contributes to the normal movement of their contents, often cannot be solved with just a change in diet and lifestyle changes. Reviews of Debridat indicate that it is one of the most effective and gentle medicines, which is a kind of synthetic muscle that can make both the stomach and intestines work normally. Trimebutine, the active ingredient in Debridat, is an agonist of peripheral opiate μ-, κ- and δ-receptors, which are found in the smooth muscle cells of the gastrointestinal tract and in the enteric nervous system. It acts as a myotropic antispasmodic. In addition, it has properties uncharacteristic for this group of drugs:

• Modulates the motor function of the gastrointestinal tract, which is manifested in its ability to normalize hypo- and hyperkinetic motility disorders in therapeutic and surgical pathologies;
• Has an analgesic effect.

That is, in case of hypokinetic disorders, trimebutine is regarded as a prokinetic agent. Its high effectiveness in treating hyperkinetic disorders and as a remedy for abdominal pain allows it to be classified as an antispasmodic drug.

General information

Often, problems with the gastrointestinal tract arise due to impaired functionality of intestinal motility. As a result, spasm occurs and intestinal motility deteriorates. The reasons for these violations are:

• pathological processes affecting the deterioration of intestinal functions;
• oncological formations;
• lack of defecation reflexes;
• intestinal overcrowding that occurs when you refuse to have bowel movements;
• stress loads that cause irregular bowel movements;
• presence of low physical activity;
• vascular disorders that reduce the nutrition of the intestinal walls.

All of the above conditions can cause disruptions in the functioning of both the stomach and intestines. Thanks to the substance trimebutine included in Debridat, the drug can have a stimulating effect on intestinal motility and at the same time act as an antispasmodic.

The drug coats all the walls of the stomach and intestines. This effect of the drug reduces the load on the esophageal sphincter and promotes natural bowel movements.

Properties of the medicine

When taking Debridat throughout the entire period of treatment, intestinal motility increases and its walls strengthen. As a result of treatment with the drug it is possible:

1. achieve complete normalization of stool,
2. eliminate pain syndromes and discomfort in the gastric region,
3. get rid of increased gas formation and phenomena associated with flatulence,
4. get rid of the symptoms of dyspepsia,
5. eliminate nausea and vomiting.

Giving up your usual diet does not always help to cope with unwanted changes in the activity of the stomach and intestines. Only in combination with Debridat can improvement of the functions of the digestive tract be achieved.

This is evidenced by reviews from both doctors and patients. The product is distinguished not only by its effectiveness, but also by its safety.

The active component, trimebutine, includes peripheral opiate receptors contained in the smooth muscles of the stomach and intestines and in enteric nerve cells.

Its effect is aimed at eliminating spasm.

In addition, the drug has the following properties:

• strengthens the motility of the digestive tract,
• has an analgesic effect,
• relieves intoxication.

Debridate suspension is the choice of pediatricians for intestinal colic in newborns

Debridate suspension is the choice of pediatricians for intestinal colic in newborns

Intestinal colic is diagnosed in more than 90% of newborns. As a rule, such a problem period in infants takes from 3 to 4 months, provided that the baby is properly managed.

Correct management of newborns with intestinal colic means strict adherence to the following rules:

1. Feeding on demand, but with control of the incoming volume of milk and/or formula.
2. It is mandatory to hold the child in an upright position after each feeding until episodes of air escaping from the stomach occur.
3. Full day and night sleep.
4. When breastfeeding, strict adherence to the diet by the nursing mother.
5. In the case of artificial or mixed feeding, the use of highly adapted formulas to feed the child.
6. Whole milk should not be present in a child's diet.
7. Do not introduce various foods into complementary foods before the required time.
8. With the development of colic, which does not allow the child to eat properly, leads to constant crying, poor sleep, irritation, diarrhea/constipation, bloating, vomiting, and refusal to eat, use medications prescribed by the pediatrician.
9. Do not independently treat a newborn on the advice of grandmothers, neighbors, friends, or recommendations from non-professional Internet sources.

Parents need to understand that a child who has intestinal colic feels just as bad as an adult with digestive problems. An adult in such situations will not apply warm diapers to his stomach or drink dill water, since this can only help with a minimal degree of digestive disorders, when the process may stop on its own. An adult will seek help from a doctor and begin taking medications to relieve unpleasant symptoms and prevent the development of complications.

If colic causes pain, unpleasant symptoms, and the mother sees that the child is unwell, it is necessary to fully follow all the pediatrician’s recommendations. One of these mandatory prescriptions is the recommendation to buy Debridat suspension.

The drug Debridat is produced in the form of a suspension, which is approved for use by children from birth, as well as in the form of tablets, which can be used by children from 3 years of age and adults.

The drug is an antispasmodic with a selective mechanism of action. Due to its special sensitivity to pain and other receptors, Debridat regulates the motor activity of the digestive tract along its entire length. The advantage of the drug, unlike other antispasmodics, is the complete absence of influence on the central nervous system.

With the help of this feature, in case of any functional disorder of the gastrointestinal tract, Debridat completely restores intestinal motility. Moreover, the selectivity of the drug’s action allows it to recognize areas in the intestine with reduced motility and enhance it, and areas of the gastrointestinal tract with increased contractility of intestinal smooth muscles undergo relaxation with normalization of their tone.

Thus, to buy Debridat for newborns for colic is to help the child get rid of pain, bloating, diarrhea, constipation, frequent regurgitation, and vomiting.

The drug is completely harmless for children of any age, which is confirmed by a large number of studies in which children from 0 months to 5 years took part.

The disadvantage of the treatment is that such a medicine is available only to residents of Europe, but it is not sold in our pharmacies. With the advent of our online pharmacy, treatment of colic in infants is now carried out in a timely manner, since Debridat can be bought in Moscow at any time from us.

We deliver high-quality, effective and safe drugs from Europe to the population of our country. The drugs we deliver have all quality certificates, as they are produced by the world's best manufacturers. In addition, the process of transporting any medicine occurs in strict accordance with the storage rules for each individual medicine.

Instructions for use

Debridat solution is administered intramuscularly or intravenously; a single dose should not exceed 50 mg.

Adult patients take the drug 1 or 2 tablets per day, which is from 100 to 200 mg. If necessary, the drug is prescribed in the form of a suspension three times a day, 1 or 2 large spoons.

For treatment, children are prescribed powder from which a suspension is prepared; the dosage is selected by the doctor depending on the age of the child.

It is usually prescribed three times a day, half a small spoon of the suspension, for children up to six months, twice a day, a whole teaspoon for children up to one year old, three times a day, a teaspoon for children under 5 years old, three times a day, two teaspoons for children over 5 years old.

Cost and analogues

In addition to the above remedy, a lot of drugs are produced that have identical properties. If the pharmacy does not have the required drug, you can purchase analogues of Debridat, such as: Valenta Trimedat, Neobutin or Retard Neobutin.

The cost of the drug varies depending on the manufacturer and the pharmacy chain in which it is sold. The regular price of Debridat in Moscow is 2 thousand rubles. If some patients do not have the necessary funds to purchase the drug, then identical drugs can be used.