- November 24, 2019
- dietary supplement
- Elena Kerra
The benefits of vitamins have been repeatedly confirmed by scientific research and no one doubts them. Doctors recommend taking them to adults and children to strengthen the immune system and increase vitality, to normalize metabolism and stabilize body functions after illnesses.
There are many vitamin complexes in pharmacies. Each of them has its own composition, which determines the range of therapeutic properties. Today, “Dekamevit” is considered one of the best, the instructions for which are discussed in this article. We will tell you who this drug is prescribed to, whether it can cause side effects, and whether it has analogues.
general information
Vitamins "Dekamevit" are a medicine, which should be taken into account by everyone who is going to take it. The drug is produced by the Kiev Vitamin Plant, as well as Russian (located in St. Petersburg) and OJSC UfaVita. This multivitamin complex has been on the pharmaceutical market for more than 30 years. During this time, thousands of people have become convinced of its effectiveness.
The period of use of "Dekamevit" is 24 months. The release date is indicated on the packaging. You can store vitamins in your living room (not in the refrigerator), in a dry place out of reach of children.
The drug is sold in pharmacies without a prescription.
Decamevit price, where to buy
The price of Decamevit for package No. 20 in pharmacies in Moscow and other cities of Russia varies from 198 to 234 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
LuxPharma* special offer
- Decamevit tab.
p/o 20pcs 1600 rub. order
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Pharmacy24
- Decamevit N20 tablets PAT "Kiev Vitamin Plant", Kiev, Ukraine
53 UAH. order
Release form
Vitamins "Dekamevit" are produced in blisters. Each contains 10 tablets, covered with a yellow coating.
Blisters in the amount of 2 pieces are packed in a cardboard box. It must contain instructions for use.
Vitamins "Dekamevit" from are also available in glass bottles. Each contains 20 tablets, no different from those in blisters. Vitamins produced in Ukraine and Russia have the same composition. The only difference is in the packaging design. Russian manufacturers have it more laconic.
Description of the drug
In reviews of Decamevit, users note that the pills are quite large (diameter more than 1 cm), so they are not convenient for everyone to swallow. They are covered with a yellow shell that tastes sweet. The jelly beans easily turn the tongue yellow.
Under the shell are the vitamins themselves. The drug tastes sour and bitter and has an unpleasant odor. You can feel it if you suck or chew the pills, despite the fact that this is prohibited by the instructions.
Consumer Reviews
The multivitamin complex "Dekamevit" has different reviews. Some say that the drug helps to recover from illnesses; it is especially good to take it after poisoning. Improvements are noticeable almost after several days of taking the pills. These people note the budget cost of multivitamins. They claim that they have everything you need and nothing you don't need. They are considered the best for combating vitamin deficiency.
There are also negative opinions. So, people say that this drug contains few vitamins. It does not contain microelements or amino acids. Some people did not feel any results after using it. Users also note the large size of the tablets, which makes them uncomfortable to drink.
Composition of the drug
"Dekamevit" includes the following main active ingredients:
- Vitamin A (rethiol acetate) – 6600 IU.
- Dry vitamin E (or a-tocopherol acetate) – 10 mg.
- Thiamine hydrochloride (vitamin B1) – 20 mg.
- Riboflavin (vitamin B2) – 10 mg.
- Pyridoxine hydrochloride (vitamin B6) – 20 mg.
- Folic acid (vitamin B9) – 2 mg.
- Cyanocobalamin (vitamin B12) – 0.1 mg.
- Rutin (vitamin P) – 20 mg.
- Nicotinamide (niacin, or vitamin PP) – 50 mg.
- Methionine – 200 mg.
- Ascorbic acid (or vitamin C) – 50 mg.
According to the instructions for the drug "Dekamevit", this drug also contains additional components that provide the dragees with their shape and color, as well as increase the absorption of the main active ingredients. This:
- Magnesium stearate.
- Croscarmellose sodium.
- Talc.
- Blends of Opadry AMB II White and Opadry II Yellow (used for film coating).
- Titanium dioxide
- Polyvinyl alcohol.
- Glycerol monocaprylocaprate.
- Yellow quinoline varnish (E104).
- Sodium lauryl sulfate.
- Medium chain triglycerides.
- Polydextrose hypromellose.
- Titanium dioxide (E171).
- Maltodextrin.
Therapeutic effect
Vitamins “Dekamevit” have many beneficial properties for the human body, which is ensured by the rich composition of the drug:
- Vitamin A has a beneficial effect on vision, increases the barrier functions of mucous membranes, increases phagocytosis of leukocytes, restores epithelial cells, reduces the risk of various infections, and promotes skin regeneration during injuries, including burns. It helps to recover faster from flu and colds, and helps people with AIDS survive.
- Vitamin B1 improves memory, intelligence, thinking and mood, slows down aging, promotes the growth of muscle and bone tissue. It also stabilizes the functioning of the cardiovascular system and gastrointestinal tract.
- Vitamin B2 is needed for the formation of antibodies and red blood cells. It ensures normal functioning of the thyroid gland, has a positive effect on the condition of nails, hair, skin, stimulates reproductive function, helps cells absorb iron, and reduces the effect of harmful substances on the respiratory tract.
- Vitamin B6 improves skin condition, stabilizes the functioning of the nervous system, and takes part in the creation of antibodies and red blood cells. It helps transform the essential amino acid tryptophan into vitamin B3 (niacin). In addition, it fights aging, helps avoid nighttime muscle cramps, and helps lower blood sugar levels.
- Vitamin B9 is involved in the synthesis of blood cells (leukocytes, platelets and red blood cells), as well as in the formation of amino acids and RNA, promotes the regeneration of skin cells and hair growth. This substance affects the production of serotonin (“the joy hormone”). With its deficiency, depression and stress occur.
- Vitamin B12 takes part in hematopoiesis and the formation of nerve fibers, helps improve appetite, improves memory and concentration. This substance also reduces irritability and prevents anemia.
- Vitamin C is a powerful antioxidant. It protects a person from infection by viruses and bacteria, promotes rapid tissue regeneration, and participates in the synthesis of certain hormones, proteins and collagen.
- Vitamin P strengthens the walls of venules, arterioles and capillaries, prevents bleeding gums, inhibits the growth of tumor cells, and reduces intraocular pressure. This substance (together with ascorbic acid) takes part in the formation of collagen and improves gas exchange in cells.
- Vitamin PP is part of very important enzymes that ensure respiration at the cellular level, improves the functioning of the cardiovascular, nervous and digestive systems. This substance prevents the degeneration of normal cells into cancer cells.
- Vitamin E is one of the most powerful antioxidants. It slows down cell aging, protects the skin from the adverse effects of ultraviolet radiation, improves blood circulation and tissue regeneration, helps lower blood sugar levels, and prevents the development of cancer cells in the bladder and prostate.
- Methionine is a hormone that regulates human daily biorhythms. It has antitumor and antioxidant properties, normalizes sleep, reduces anxiety, and improves mood.
All vitamins help strengthen the immune system and normalize metabolism.
Pharmacological properties
Pharmacodynamics.
A multivitamin medicine, the properties of which are determined by the vitamins included in its composition and which take an active part in almost all biochemical reactions of the body. A rationally selected composition contributes to the manifestation of a more pronounced and versatile biological effect of the drug.
Vitamin A (retinol acetate) is necessary for the development of epithelial cells and the synthesis of visual pigment.
Vitamin E (a-tocopherol acetate) is a fat-soluble vitamin that has a pronounced antioxidant and radioprotective effect, takes part in the biosynthesis of heme and proteins, cell proliferation and other most important processes of cellular metabolism, improves oxygen consumption by tissues, and also has an angioprotective effect, affecting vascular tone and permeability, stimulating the formation of new capillaries.
Vitamin B1 (thiamine hydrochloride) normalizes the functional activity of the nervous, cardiovascular and digestive systems.
Vitamin B2 (riboflavin) plays an important role in protein, fat and carbohydrate metabolism, takes part in maintaining normal visual acuity, and normalizes skin functions.
Vitamin B6 (pyridoxine hydrochloride) is necessary for the regeneration of the skin and liver cells, restoration of the functioning of the nervous system, and improves fat metabolism in atherosclerosis.
Vitamin C (ascorbic acid) plays an important role in the regulation of redox processes, carbohydrate metabolism, blood coagulation, tissue regeneration, normal capillary permeability, the formation of steroid hormones and connective tissue components, and helps increase the body's resistance to infectious diseases.
Vitamin Bc (folic acid), in addition to its antianemic effect during pregnancy, protects the fetus from the influence of teratogenic factors and takes part in the metabolism and synthesis of amino and nucleic acids.
Vitamin PP (nicotinamide) is a specific anti-pellagric agent that improves carbohydrate metabolism.
Vitamin P (rutin) – P-vitamin-like water-soluble substance, flavonoid. Rutin interacts with ascorbic acid, takes part in the regulation of collagen formation in connective tissue, prevents the depolymerization of hyaluronic acid by hyaluronidase, and activates tissue respiration.
The essential amino acid methionine plays a role in the synthesis of a number of biologically important compounds, activates the effects of hormones, vitamins and enzymes, and neutralizes toxic products.
Vitamin B12 (cyanocobalamin) affects the processes of normal maturation of all cells of the body, especially blood and liver cells, and has a positive effect on the functioning of the nervous system and liver.
Pharmacokinetics.
Fat-soluble vitamins included in the drug (vitamin A, vitamin E) can be deposited in tissues. Water-soluble vitamins (vitamins B1, B2, B6, B12, C, PP) are converted into coenzymes and, combining with the apoenzyme, are part of complex enzymes. Since the lifespan of enzymes is limited, coenzymes break down and are excreted from the body in the form of various metabolites. Fat-soluble vitamins are also catabolic and excreted from the body, although more slowly than water-soluble vitamins.
Pharmacokinetics
According to the instructions for use, “Dekamevit” contains fat-soluble and water-soluble vitamins. The first accumulate in tissues. The latter are transformed and are part of enzymes important for the functioning of the body. Excreted in urine in the form of metabolites. Fat-soluble vitamins undergo catabolism much more slowly and are removed from the body mainly through bile.
Analogs
Analogues of dekamevit include:
- Pikovit forte;
- Hexavit;
- Multi tabs;
- Vetoron;
- Complivit;
- Makrovit;
- Soluvit N;
- Neuromultivitis;
- Vitalipid N (for children and adults);
- Neurorubin.
All these medications are similar in composition to Decamevit. They saturate the body with vitamins, preventing early aging and improving well-being.
Contraindications
Despite the many therapeutic properties, the use of Decamevit is prohibited for the following diseases and conditions:
- intolerance to any substance included in the drug;
- thyrotoxicosis;
- erythremia;
- chronic glomerulonephritis;
- thromboembolism;
- gout;
- hyperuricemia;
- hypervitaminosis;
- erythrocytosis;
- fructose intolerance;
- history of sarcoidosis;
- chronic heart failure;
- stomach ulcer (with exacerbation).
There are categories of patients who can take Decamevit, but with caution and only after consulting a doctor. This rule applies to people suffering from the following ailments:
- renal failure;
- acute nephritis;
- cholelithiasis;
- chronic pancreatitis;
- diabetes;
- cardiac ischemia;
- the presence of neoplasms in the body;
- anemia of unknown etiology;
- presence of glucose-6-phosphate dehydrogenase deficiency;
- hemochromatosis;
- thalassemia;
- leukemia;
- polycythemia.
Application Features
Women who have used large doses of retinol (over 10,000 IU) can plan pregnancy no earlier than 6-12 months later. This is due to the fact that during this time there is a risk of improper development of the fetus under the influence of a high content of vitamin A in the body.
It is possible that urine may turn yellow, which is completely harmless and is explained by the presence of riboflavin in the drug.
Use with caution in patients with kidney disease, severe liver damage, a history of peptic ulcer of the stomach and duodenum, acute nephritis, cardiac decompensation, cholelithiasis, chronic pancreatitis, coronary heart disease, diabetes mellitus.
The drug should be prescribed with caution to patients with neoplasms (except for cases accompanied by megaloblastic anemia).
The drug is prescribed with caution to patients with anemia of unknown etiology, since folic acid may interfere with the diagnosis of pernicious anemia by improving the hematological manifestations of the disease, while allowing the progression of neurological complications.
When using high doses or long-term use of the drug, it is necessary to monitor blood pressure levels. Simultaneous use of the drug with an alkaline drink reduces the absorption of ascorbic acid, so you should not drink it with alkaline mineral water. Also, the absorption of ascorbic acid may be impaired by intestinal dyskinesia, enteritis and achylia. Use with caution to treat patients with glucose-6-phosphate dehydrogenase deficiency. Ascorbic acid may interfere with laboratory results. For example, when determining the content of glucose, bilirubin, transaminase activity, lactate dehydrogenase in the blood.
Large doses of the drug should not be prescribed to patients with increased blood clotting.
Because ascorbic acid increases iron absorption, high doses may be harmful to patients with hemochromatosis, thalassemia, polycythemia, leukemia, and sideroblastic anemia. Patients with high iron content in the body should use the drug in minimal doses.
Since ascorbic acid has a slight stimulating effect, it is not recommended to use the drug at the end of the day.
Use during pregnancy or breastfeeding.
During pregnancy or breastfeeding, use the drug only on the recommendation of a doctor.
The dose of vitamin A should not exceed 5,000 IU for pregnant women and women planning to become pregnant.
Large doses of retinol (over 10,000 IU) should not be used by women during breastfeeding due to the risk of developing hypervitaminosis A in infants.
The ability to influence the reaction rate when driving vehicles or other mechanisms.
Drivers and operators of complex machinery should consider the possibility of side effects such as dizziness and drowsiness.
Special conditions
The instructions for use of Decamevit indicate what you need to pay attention to when treating with this drug:
- After taking the pills, your urine may turn bright yellow. This is not a pathology and is caused by the presence of riboflavin in Decamevit.
- Women who have undergone treatment with drugs containing large amounts of vitamin A can plan pregnancy only after six months (and in some cases after a year), since retinol can cause disturbances in the development of the fetus.
- During long-term treatment with Decamevit, it is necessary to keep blood pressure under control, as surges may occur. For patients with increased blood clotting, the drug is prescribed in minimal doses.
- Decamevit is best taken in the morning or in the middle of the day. Evening intake may cause insomnia.
- It should be taken into account that vitamin C can influence the results of blood tests when determining bilirubin, glucose, transaminase and lactate dehydrogenase activity.
- Drivers and people whose work involves the operation of complex machinery should be aware that multivitamins may cause drowsiness and dizziness.
Reviews about Decamevit
Patients who took the multivitamin leave positive reviews about Decamevit. The drug helps fight fatigue, quickly restores performance, increases vitality and improves mood. Decamevit is equally effective in young, middle-aged and elderly patients.
However, recently the drug is practically not found in pharmacies; it is problematic to buy it, which patients often complain about on medical portals and forums.
Overdose
This condition cannot be excluded, since not all patients perceive vitamins as a medicine. The sweetish taste of the dragee and the bright colorful packaging of “Dekamevit” contribute to the fact that children mistake this product for candy. If the drug is in a place accessible to children, they can eat a lot of pills at once.
Overdose is sometimes observed in adults who, when taking the drug, exceed the doses indicated in the instructions. The following symptoms may occur:
- abdominal pain;
- allergic reactions in the form of rash, itching, redness of the skin;
- diarrhea;
- nausea and vomiting;
- liver dysfunction;
- drowsiness;
- facial hyperemia;
- lethargy;
- irritability;
- headache.
If a child accidentally eats several Decamevit tablets, you should try to induce vomiting, and then give him any sorbent to drink. If the child's condition worsens, you must call an ambulance.
Side effects
In most cases, the drug does not cause any unwanted reactions from the body. However, the possibility of the following side effects cannot be ruled out:
From the cardiovascular system:
- increase or decrease in blood pressure;
- myocardial dystrophy;
- arrhythmia;
- tachycardia.
From the NS side:
- headache;
- drowsiness or insomnia;
- fatigue, lethargy or increased excitability, irritability;
- dizziness;
- feeling of heat.
From the gastrointestinal tract:
- diarrhea or constipation;
- heartburn;
- bitterness in the mouth;
- anorexia;
- nausea and vomiting.
From the urinary system:
- crystalluria;
- formation of kidney stones;
- renal failure;
- formation of stones in the ureters.
From the lymphatic and circulatory systems:
- thrombocytosis;
- erythrocytopenia;
- hypoprothrombinemia;
- thrombosis;
- neutrophilic leukocytosis;
- hemolysis of erythrocytes and hemolytic anemia (in the presence of deficiency of glucose-6-phosphate dehydrogenase of erythrocytes).
From the endocrine system:
- glucosuria;
- hyperglycemia;
- disruptions in glycogen synthesis.
In addition, taking Decamevit can cause:
- increased sweating;
- vision problems;
- the appearance of cracks on the feet and palms;
- hair loss;
- irritation of the gastrointestinal mucosa;
- hyperthermia;
- bronchospasms (with hypersensitivity to B vitamins, retinol and ascorbic acid);
- allergic reactions, up to anaphylactic shock.
Interaction with other medications
The drug contains many components, each of which has its own characteristics when taken together with various medications and substances. The main ones are:
- According to the instructions for use, Decamevit should not be taken simultaneously with other vitamins. Otherwise, hypervitaminosis may occur.
- Large doses of the drug reduce the effectiveness of neuroleptics, tricyclic antidepressants, and interfere with the excretion of Mexiletine by the kidneys.
- "Dekamevit" is not prescribed together with nitrites and cholestyramine, since these substances reduce the absorption of vitamin A. Retinol reduces the anti-inflammatory effect of glucocorticosteroids.
- Vitamin C should not be taken together with sulfonamides, as crystalluria may occur. Also, ascorbic acid reduces the effects of heparin and indirect anticoagulants, but enhances the absorption of iron and aluminum.
- Vitamin B2 and streptomycin cannot be combined. Riboflavin reduces the effectiveness of treatment with Doxycycline, Erythromycin, Oxytetracycline, Lincomycin and Tetracycline.
- Vitamin B9 taken together with antiepileptic drugs reduces the effectiveness of treatment. The absorption of folic acid is reduced when taken simultaneously with analgesics, antacids, antibiotics, sulfonamides, cytostatics and anticonvulsants.
The drug should not be taken with alkaline mineral water.
Interaction
It is not recommended to take Decamevit vitamins simultaneously with other medications containing vitamins, as well as cholestyramine and nitrites , since these drugs impede the absorption of retinol .
retinoids should not be prescribed simultaneously - this combination is toxic.
Vitamins A and E are synergists (strengthen their mutual effect). Retinol reduces the effectiveness of glucocorticoids . Vitamin C enhances the effect of penicillin and sulfonamides , increases the absorption of iron , and reduces the effectiveness of heparin . When vitamin C is prescribed simultaneously with oral contraceptives, its absorption is reduced.
Iron preparations reduce the effectiveness of vitamin E, so it cannot be prescribed together with silver, iron preparations and alkaline agents ( Trisamine , sodium bicarbonate), indirect anticoagulants.
Thiamine may weaken the curare-like effect. Riboflavin should not be prescribed with Streptomycin . In addition, Riboflavin reduces the effect of antibacterial drugs ( Erythromycin , Oxytetracycline
,
Tetracycline and Doxycycline ).
Reviews
“Dekamevit,” the instructions for use of which are discussed in the article, is considered by many people to be the best vitamin complex. This drug helps strengthen the immune system after suffering from various diseases, perfectly restores the body’s strength, and as part of a complex treatment helps to cope with dozens of ailments. Among the advantages of Decamevit, users name its availability and relatively low cost. In Moscow, this drug can be bought for 1,200 rubles.
But Decamevit also has its drawbacks. Many people don’t like that the pills are too large, have a specific smell, and stain the tongue.
Some people also note the fact that the drug has a lot of side effects and contraindications.
Indications for use
If we study the reviews of specialists, we can conclude that in case of hypo- and vitamin deficiency, the drug “Dekamevit” is often prescribed to patients. Instructions for use recommend using the product for vitamin deficiency resulting from physical and mental exhaustion. The indication for use is the recovery period after surgery. Multivitamins are prescribed to older people, after illnesses and after a long course of antibiotics.