Description and composition
The active ingredients in the drug are magnesium citrate and pyridoxine hydrochloride. Compared to regular Magnelis, the forte form contains 2 times more active ingredients.
Magnesium is vital for a person of any age and gender. It is involved not only in the functioning of all cells of the body, but also takes part in metabolic processes and the transmission of nerve impulses. Magnesium content is of great importance for the functioning of the muscular system.
The accumulation of this microelement occurs mainly in bone tissue, however, with insufficient dietary intake, magnesium is consumed very quickly. With a deficiency, convulsions, disturbances in the psycho-emotional background, changes in general well-being and health status may occur.
B vitamins are extremely important for the functioning of the nervous system, as well as for maintaining healthy skin, hair, nails and overall appearance. Pyridoxine takes part in many metabolic processes, so its deficiency can greatly affect the health of the entire body. In addition, this vitamin promotes more complete absorption of magnesium from the gastrointestinal tract, due to which the microelement better reaches many organs and tissues. Thus, the combined composition increases the overall effectiveness of the drug.
Magnesium deficiency can occur when there is insufficient intake of the microelement from food or when its need increases, which, for example, often occurs during pregnancy or exercise.
Composition of the drug and its form of production
One tablet contains about 618.43 mg of magnesium citrate (which is proportional to 100 mg of magnesium) Magnelis B6 Forte. The composition is supplemented with pyridoxine hydrochloride (vitamin B6) in the amount of 10 mg. Additional components in the dragee are ludipress, crospovidone, macrogol 6000, magnesium stearate. The tablet shell contains hypromellose, titanium dioxide, macrogol-3350 and talc.
The capsule has an oval shape and convexities on both sides, without marks. Covered with a white shell. Tablets of ten pieces are enclosed in an aluminum blister. The package may contain three, six or nine blisters, which corresponds to 30, 60 and 90 tablets. In addition to the medicine, the box contains instructions for use.
Indications for use
for adults
Indications for use are conditions caused by magnesium deficiency in the body. Among them, the official instructions note the following:
- increased irritability;
- sleep disturbance;
cardiopalmus;
- muscle soreness or cramps;
- increased fatigue;
- gastrointestinal cramps;
- tingling in muscles.
It should be remembered that such symptoms can be caused not only by magnesium deficiency. If treatment with Magnelis is ineffective, the patient is recommended to undergo a more complete examination and look for another cause of the pathological conditions.
for children
The use of the drug in children is allowed only from 12 years of age. However, the indications for use remain the same as for adult patients. Magnelis B6 forte can be used in cases where a child’s body is deficient in magnesium and corresponding clinical manifestations occur.
for pregnant women and during lactation
The drug is approved for use during pregnancy and breastfeeding. Moreover, a frequent indication for the use of Magnelis B6 forte is increased uterine tone and unstable psycho-emotional state of the pregnant woman - symptoms that are effectively eliminated by this drug.
In clinical trials, the combination of magnesium citrate and pyridoxine hydrochloride did not result in any adverse effects in the fetus or newborn child.
Patient reviews
They say that Magnelis B6 Forte tablets are good for calming, relieving tension and eye tics. Reviews for neurosis note the effectiveness of the drug for insomnia, prolonged stress and depression. When treating these and other ailments, it does not cause drowsiness. Magnelis B6 Forte also perfectly relaxes the nervous system and replenishes magnesium deficiency. Reviews from pregnant women say that the tablets remove the tone of the uterus and make the stomach soft. They have a calming effect and normalize sleep.
Many people take pills for cramps, heaviness and discomfort in their legs. Since this is a strengthened formula, you need to take fewer tablets per day than when taking just Magnelis B6. Users also note the affordable price of the product. The drug is said to contain the most easily digestible form of magnesium - magnesium citrate. It is used for excessive mental and physical stress, as well as for rapid fatigue. Patients took the pills to treat rapid heartbeat and muscle pain. Often the drug helps already in the first week of use, although you need to take it for a month. Many continue to take pills, but to prevent past diseases, a couple of times a year.
There are people who call Magnelis B6 Forte useless and prefer its imported analogue Magne B6. They claim that the latter is more effective and you can achieve the desired result faster, although it costs twice as much.
In general, Magnelis B6 Forte fully copes with its task. Acts quickly, effectively and gently. Most patients are satisfied with the effect this drug gives.
Contraindications
The official instructions indicate the following conditions as contraindications:
- hypersensitivity to the main or auxiliary component;
- severe renal failure;
- simultaneous use of drugs that are not recommended for use together with Magnelis B6 forte;
- hereditary galactosemia or lactose metabolism disorder;
- The patient's age is up to 12 years.
When should you not take the pills?
Despite the good results that Magnelis B6 Forte gives for sleep disorders and other diseases, it should not be used if you are hypersensitive to the constituent substances of this drug. A contraindication to the use of tablets is renal failure, which occurs in a serious form when creatinine clearance is less than 30 ml/min. This remedy is not recommended for children under the age of twelve due to the lack of necessary clinical studies.
It is forbidden to take the medicine if you have hereditary galactosemia, lactase deficiency (since the drug contains the component lactose monohydrate), as well as with galactose and glucose malabsorption syndrome. You should not combine levodopa with Magnelis B6 Forte.
The tablets are prescribed with caution for renal failure, which is characterized by moderate severity. There is a possibility of hypermagnesemia.
Magnelis B6 Forte can be used during pregnancy (reviews from pregnant women note that the tablets help remove the tone of the uterus, make the stomach softer, and are very soothing), but only as prescribed by a doctor. The product does not have a negative effect on the formation of the fetus. Magnesium can pass into breast milk, so if you use this drug, you should refrain from breastfeeding for a while.
Applications and dosages
for adults
Magnelis tablets are intended for oral administration. They should be taken whole, without chewing, and with a glass of water. The daily dosage for adults is 3-4 tablets. This amount is divided into several doses and taken at regular intervals, preferably with meals.
The standard duration of treatment is 1 month, but the course can be extended or repeated after some time.
for children
In childhood, Magnelis B6 forte is prescribed according to the same regimen as for adult patients. The daily amount of the drug can be from 2 to 4 tablets, which are divided into several doses and drunk throughout the day, for example, in the morning and evening. The standard duration of therapy is also 1 month.
for pregnant women and during lactation
The drug is approved for use during pregnancy and breastfeeding, but the treatment regimen is selected by the doctor individually for each patient. The daily amount of the drug, in most cases, corresponds to the standard regimen for adult patients, since during pregnancy the need for magnesium increases, and the drug has a high safety profile and its overdose is unlikely.
Magnelis B6 Forte: instructions for use
Capsules are taken orally. They should be swallowed whole, without chewing, with a sufficient amount of liquid.
Adults are prescribed three or four pills a day. They must be divided into 2-3 doses. The product is taken with food. Children over twelve years of age take two or four tablets per day. This number of capsules should be distributed 2-3 times.
The instructions recommend taking Magnelis B6 Forte for a month. If the symptoms of magnesium deficiency have not disappeared during this time, then further use of the drug is not advisable.
Interaction with other drugs
It is not recommended to take Magnelis B6 forte simultaneously with levodopa, since the effectiveness of the latter is reduced due to pyridoxine.
Magnesium with phosphate or calcium salts is also considered a bad combination, since the absorption of magnesium in the intestine is difficult.
If combination therapy with tetracycline is necessary, the interval between taking this drug and Magnelis should be at least 3 hours.
special instructions
The drug is not allowed to be used by patients under 12 years of age
It should be remembered that Magnelis B6 forte contains lactose, which is not suitable for patients with impaired metabolism of this substance.
Kidney failure can cause increased concentrations of magnesium in the blood due to its slow elimination.
The use of high doses of pyridoxine for a long time can lead to unwanted symptoms from the nervous system. Of these, numbness, changes in sensitivity, tremor and others are often noted - all of them are reversible and disappear after discontinuation of the drug.
Magnelis B6 forte in recommended doses does not affect the ability to drive vehicles or work with potentially dangerous mechanisms.
Magnelis b6
Magnelis B6 is a combined two-component drug to eliminate magnesium deficiency when its level decreases below the physiological norm. The presence of this macroelement in all tissues of the body without exception is the best proof of its importance: without magnesium, the normal functioning of organs and systems is unthinkable. This macroelement is an invariable participant in the vast majority of metabolic reactions. It regulates the conduction of electrical signals propagating along the axons of nerve cells, controls the contraction of muscle fibers, prevents spasms of smooth and striated muscles, maintains a normal heart rhythm, and prevents excessive adhesion of platelets to each other. Magnesium enters the body with food. A deficiency of this macroelement can develop due to errors in diet (non-compliance with the diet), excessively intense physical activity, excessive psychological stress, during pregnancy and when taking diuretic medications (in such circumstances, the need for magnesium increases, which requires its additional intake into the body) . The second component of the drug, pyridoxine, is required by the body in many metabolic reactions, in the control of metabolic processes occurring in the central and peripheral nervous system. After oral administration, approximately half of the administered dose of magnesium is absorbed in the gastrointestinal tract and enters the systemic circulation. Elimination from the body occurs through urine. The daily dose for adult patients is 6-8 tablets. The daily dose and the possibility of prescribing the drug to children depend on age and body weight: the drug can be taken by patients over six years of age, provided that their body weight exceeds 20 kg. In this case, the daily dose of the drug is 4-6 tablets. The frequency of administration of the drug for patients of all ages is 2-3 times a day. The signal for ending the medication course is to bring the level of magnesium in the blood to the physiological norm.
The optimal time to take the medicine is during meals. Possible undesirable side reactions: epigastric pain, delayed, difficult or systematically insufficient defecation, painful sensation in the epigastric region, chest, oral cavity and pharynx, often preceded by vomiting or vomiting itself, increased gas formation, skin rashes, urticaria, sensation of painful tickling skin irritation , causing the need to scratch the irritated area. The drug is not prescribed for severe renal failure, phenylketonuria (phenylpyroviral oligophrenia), individual intolerance to any of the active components of the drug or any excipient. Particular caution when prescribing the drug should be observed in persons with moderate renal insufficiency, because In patients of this profile, there is a possibility of an increase in the total concentration of magnesium in the blood plasma above the physiological norm. The drug does not have a toxic effect on the fetus and does not cause mutations, so it can be used during pregnancy, but subject to mandatory medical supervision. Given the possibility of penetration and subsequent release of magnesium along with breast milk, the use of the drug during breastfeeding is undesirable. When prescribing the drug to patients suffering from diabetes, it is necessary to take into account that the drug contains the disaccharide sucrose as one of the excipients. If a lack of magnesium is accompanied by a calcium deficiency, then before starting to take calcium supplements, a course of treatment with Magnelis B6 should be carried out to bring the magnesium level within the physiological norm. Magnelis B6, as well as other drugs containing magnesium, reduce the absorption of the antibiotic, which may require an increase in the dose of the latter during antibacterial therapy.
Overdose
An overdose of the drug is unlikely. Patients with impaired renal excretory function have an increased risk. An overdose can lead to the following symptoms:
- nausea, vomiting;
- disruption of the central nervous system;
- respiratory depression;
- heart failure.
The severity of symptoms depends on the degree of overdose. If any of the above symptoms appear, the removal of magnesium from the body should be accelerated and rehydration should be carried out.
Analogs
The following drugs have a similar therapeutic effect:
- Magnerot. A magnesium-based drug that is prescribed only to adult patients. It is used as part of complex therapy for diseases of various fields of medicine - cardiology, gynecology, neurology and others.
- Magwit. A drug that also contains a combination of magnesium and pyridoxine. Pharmacological effects are similar to Magnelis B6 forte.
- Magne B6 Premium. A drug that is also used for magnesium deficiency in the body and is often prescribed to pregnant women. The medicine helps to normalize the functioning of the nervous system, eliminate increased excitability, improve sleep quality, and prevent muscle cramps. Can be prescribed to patients over 6 years of age.
Doctors' reviews about the drug
The drug Magnelis B6 Forte has an affordable price and helps many patients with magnesium deficiency. Reviews from gynecologists note its effectiveness in uterine tone in the II-III trimesters of pregnancy and for the prevention of magnesium deficiency.
Neurologists use this drug to relieve stress and normalize sleep. It is prescribed for depression, nervousness, and temporary numbness of the limbs. The drug has proven effective in treating certain heart diseases. In addition, the product is well tolerated by the body, has a convenient form of administration and a reasonable price.
This remedy is not prescribed to children, but instead its foreign analogue, Magne B6, is always recommended. They say that Magnelis B6 Forte is difficult for children to tolerate and often causes allergic reactions.
It is not recommended to take the drug “Magnelis B6 Forte” on your own, without a doctor’s prescription, according to doctors’ reviews. They indicate contraindications and possible negative effects that occur when medications are taken incorrectly. It is noted that an overdose of magnesium is no less harmful than a deficiency of this element. It is advised to undergo appropriate tests before using this product.
