Mikozhinaks suppositories: instructions, indications for use, composition, analogues

Manufacturer: Mekophar Chemical-Pharmaceutical JSC
Active ingredients

Not indicated. See instructions

Pharmacological action

Not indicated. See instructions

Description of the pharmacological action of Mikozhinax
Composition of Mikozhinax
Indications for use of the drug Mikozhinax
Release form of the drug Mikozhinax
Using the drug Mikozhinax during pregnancy
Contraindications to the use of the drug Mikozhinax
Side effects of the drug Mikozhinax
Method of administration and dosage of the drug Mikozhinaks
Overdose of Mikozhinax
Interactions of the drug Mikozhinax with other drugs
Special instructions when taking Mikozhinax
Shelf life of the drug Mikozhinax

Indications for use

Treatment: bacterial vaginitis caused by common pyogenic flora; - trichomonas, candidiasis vaginitis; - vaginitis caused by a mixed infection: trichomonas, anaerobes (including gardnerella), yeast-like fungi; Prevention - in operative gynecology for the prevention of pre- and postoperative inflammatory complications; — sanitation of the vagina before abortion and childbirth and installation of an IUD; - before and after diathermocoagulation of cervical erosions, before intrauterine examination (hysterography).

More about the disease

Inflammation of the vaginal mucosa is accompanied by unpleasant sensations in the perineal area. Uncharacteristic discharge may be observed on underwear. The disease is often accompanied by itching, sometimes swelling and redness of the outer skin of the genital organs. Sexual contact becomes painful.

The main causes of vaginitis:

failure to comply with hygiene rules;
hypovitaminosis;
decreased immunity due to various infectious diseases;
mechanical damage to the mucous membrane due to improper douching or other manipulations;
allergic reactions;
hormonal imbalance in the body;
use of medications without a doctor’s prescription;
increased dryness of the vaginal mucosa caused by the lack of estrogen;
radiation and chemotherapy.

How to treat vaginitis? In this situation, it is important to consult a doctor who, after studying the results of laboratory tests, will prescribe effective treatment. When patients ignore antibacterial therapy, vaginitis becomes chronic.

Directions for use and doses

It is prescribed intravaginally, 1 tablet 1 time per day, usually in the evening before bedtime. Immediately before administration, the tablet must be immersed in water for 20-30 seconds. The tablet is then inserted deep into the vagina. After administration, you need to lie down for 10-15 minutes. The average duration of continuous treatment is 10-12 days. For trichomonas vaginitis, metronidazole is prescribed orally in normal doses along with local use of Mikozhinax. In case of insufficient effectiveness, local treatment is continued for another 10-12 days.

Interaction

You should not simultaneously use Mikozhinax with the following substances:

Alcohol and drugs, because the likelihood of a disulfiram-like reaction (fear of death) is high. Drinking alcohol is allowed no earlier than one day after the administration of the last vaginal suppository.
“Cyclosporine” or creatinine, with an increased concentration of which in the blood plasma the state of health worsens.

An interesting fact is that the drug can reduce the strength of latex contraceptives, which significantly increases the risk of conception.

Special instructions for use

Treatment with Mikozhinax should not be carried out during menstruation. During the course of treatment with the drug, it is recommended to abstain from sexual intercourse, as well as from drinking alcohol. If Mikozhinax is used together with oral metronidazole, especially during a repeated course of treatment, monitoring of the peripheral blood picture is necessary (due to the possibility of developing leukopenia). When treating vaginitis caused by Trichomonas vaginalis, it is advisable to carry out a parallel course of treatment of the sexual partner (with oral use of metronidazole). During pregnancy, use the drug only as directed and under the supervision of your doctor.

Side effects

Mikozhinax can cause local reactions, such as irritation and itching of the vaginal mucosa, burning, and pain in the vagina.

Considering the possibility of systemic absorption of the active substances of the drug, the possibility of developing systemic side effects cannot be excluded:

Gastrointestinal tract and hepatobiliary system: pain in the epigastric or abdominal region, diarrhea, stool disturbances, vomiting, loss of appetite, changes in taste, inflammatory processes in the oral cavity; in isolated cases - pancreatitis, hepatitis with symptoms of cholestasis, liver dysfunction;
Central and peripheral nervous system: peripheral sensory neuropathy, headache, encephalopathy, dizziness, hallucinations, convulsions, psychotic disorders, subacute cerebral syndrome (nystagmus, tremor, ataxia, dysarthria, gait disturbances);
Blood system: thrombocytopenia, agranulocytosis, neutropenia, leukopenia;
Allergic reactions: pustular rash, skin itching, urticaria, Quincke's edema, skin hyperemia, anaphylactic shock;
Other: diplopia, decreased visual acuity, red-brown urine color, false positive Nelson test results.

Best before date

24 months

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The description of vitamin Mikozhinax is intended for informational purposes only. Before starting to use any drug, it is recommended to consult a doctor and read the instructions for use. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the project does not replace consultation with a specialist and cannot be a guarantee of the positive effect of the drug you use. The opinions of EUROLAB portal users may not coincide with the opinions of the site Administration.

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Compound

The main active ingredients are the following:

Metronidazole, which has an antimicrobial and antiprotozoal effect. The action of this substance is aimed at destroying infections caused by anaerobic bacteria.
Nystatin, penetrating the cell, quickly leads to the death of the pathogenic microorganism. Nystatin is most active against fungi of the genus Candida.
Chloramphenicol, which has high activity against microbes, rickettsia, chlamys, spirochetes.
Dexamethasone is a corticosteroid that is characterized by a pronounced anti-inflammatory and immunosuppressive effect. In addition, dexamethasone has a positive effect on energy metabolism. The hormone reduces the intensity of swelling on the mucous membrane and eliminates itching sensations.

This composition of Mikozhinax suppositories allows for a comprehensive effect on infectious diseases, eliminating symptoms as effectively as possible.

Treatment

A person’s rapid recovery largely depends on the normal functioning of their own immunity. To support the patient’s body during illness, the doctor usually prescribes comprehensive treatment. Regular consumption of ascorbic acid or fruits containing vitamin C helps to shorten the duration of the disease and reduce its severity. This valuable organic compound is present in immunostimulating complexes. The chances of a quick recovery of the body are increased by quitting smoking and alcohol, increased drinking regimen and complete rest.

Therapy includes drugs that have an antiviral effect, which can have a negative effect on foreign agents at different stages of their development. Antipyretic anti-inflammatory non-steroidal drugs are prescribed. The long-proven drug “Paracetamol” has not yet lost its popularity. However, it is gradually being replaced by a fairly effective modern medicine - Ibuprofen. Basically, symptomatic therapy is carried out with the help of such drugs. Medicines for the common cold, antipyretics and expectorants are also prescribed.

To eliminate unwanted symptoms of a cold, some people use over-the-counter treatment with medications containing antihistamines, decongestants, and analgesics. As for eliminating acute signs of the disease and restoring the condition as a whole, experts find this method to be somewhat useful. The maximum therapeutic effect is achieved through a combination of decongestants and antihistamines. However, such combinations may have side effects.

Typically, after taking these medications, patients experience dry mouth, excessive drowsiness or, conversely, asomnia and slight dizziness. For the prevention and treatment of viral infections, experts recommend taking Amizon, which has a number of therapeutic effects: antipyretic, immunostimulating, anti-inflammatory, analgesic.

Effective antiviral drugs

For ARVI, adults are prescribed medications that can act directly on infectious agents. There are drugs that prevent pathogens from entering cells. Some of the drugs act as blockers and affect their enzyme systems. The most popular means are:

"Arbidol".
"Rebetol."
"Relenza."
"Orvirem."
"Virazol".
"Influcein".
"Midantan."
"Tamiflu."
"Virazol".

Despite the fact that the pharmaceutical market is rich in a wide range of products, there is a reservation from experts that there are no medications that can completely defeat viruses. This is due to the fact that pathogenic agents have already developed sufficient resistance to rimantadine and amantadine. However, doctors recommend taking antiviral drugs because they significantly reduce the risk of serious complications.

Medicine Polygynax

These are vaginal suppositories. This drug contains two antibiotics: polymyxin and neomycin. In addition to these ingredients, they also contain nystatin, an antifungal substance.

Suppositories effectively help eliminate many pathogenic microorganisms (streptococci, E. coli, ureaplasma). In addition, they are used in the treatment of fungal diseases. They perfectly treat many pathologies, including inflammation of the ovaries. Suppositories in gynecology are used to combat vaginitis, colpitis, and vulvovaginitis. Often this drug is used as a prophylactic agent before upcoming operations, childbirth, and diagnostic procedures.

Suppositories are prescribed for medicinal purposes, usually for 12 days, 1 suppository at night. If the product is used for prophylaxis, the course is reduced to 6 days.

The drug "Polygynax" is well tolerated by the body. It has a minimal number of side effects, so it extremely rarely provokes their occurrence. These may mainly be allergic manifestations

Such suppositories should be used with great caution by women who cannot tolerate soybean oil and peanuts. With long-term therapy (this is often observed when using the drug independently), microflora disturbances may occur.

Candles

According to the instructions, Mikozhinax suppositories are used in medical practice for the purpose of local treatment of gynecological diseases of an infectious nature. Vaginal tablets have an elongated shape and a yellowish tint. They are packed in a blister made of aluminum foil.

More about the disease

The main causes of vaginitis:

failure to comply with hygiene rules;
hypovitaminosis;
decreased immunity due to various infectious diseases;
mechanical damage to the mucous membrane due to improper douching or other manipulations;
allergic reactions;
hormonal imbalance in the body;
use of medications without a doctor’s prescription;
increased dryness of the vaginal mucosa caused by the lack of estrogen;
radiation and chemotherapy.

The drug will be suitable in cases where patients need to get rid of diseases caused by pathogenic microorganisms. According to the instructions, Mikozhinax suppositories can cure candidal, bacterial, trichomonas and mixed vaginitis.

In addition, suppositories can be used to prepare patients for surgery. Doctors also recommend using the medicine as a preventive measure before installing an intrauterine device, after and before diathermocoagulation (“cauterization”) and cryodestruction (“freezing”) of cervical erosion, and before an abortion.

Compound

The main active ingredients are the following:

Metronidazole, which has an antimicrobial and antiprotozoal effect. The action of this substance is aimed at destroying infections caused by anaerobic bacteria.
Nystatin, penetrating the cell, quickly leads to the death of the pathogenic microorganism. Nystatin is most active against fungi of the genus Candida.
Chloramphenicol, which has high activity against microbes, rickettsia, chlamys, spirochetes.
Dexamethasone is a corticosteroid that is characterized by a pronounced anti-inflammatory and immunosuppressive effect. In addition, dexamethasone has a positive effect on energy metabolism. The hormone reduces the intensity of swelling on the mucous membrane and eliminates itching sensations.

This composition of Mikozhinax suppositories allows for a comprehensive effect on infectious diseases, eliminating symptoms as effectively as possible.

The drug should be taken with extreme caution by those who suffer from severe neurological diseases, chronic or progressive neuropathy.

According to the instructions, Mikozhinax suppositories cannot be used if there is an individual intolerance to the main components of the drug, which belong to the group of imidazoles.

Do not use vaginal tablets during pregnancy and lactation.

Mode of application

The instructions for the Mikozhinax suppositories, which are affordable, describe a detailed treatment regimen. The medicine is intended for intravaginal use.

The suppositories should be inserted as deep into the vagina as possible, which is easiest to do in a lying position. Beforehand, vaginal tablets can be softened a little with clean water.

So, in order to use the drug as effectively as possible, you should follow simple rules:

After administering the medicinal suppository, you must remain in a lying position for about 20-30 minutes.
Doctors usually prescribe one tablet once a day, most often at bedtime.
The duration of treatment in each case is determined by the doctor individually. The duration of the course of antibacterial therapy should be no more than ten days.
In case of preparation for surgery, Mikozhinax is used five days before and five days after the operation.

Side effects

As indicated in the instructions, Mikozhinax suppositories in case of overdose can cause negative reactions such as burning, itching and irritation of the vaginal mucosa. The drug may also contribute to the development of the following conditions:

From the gastrointestinal tract: diarrhea, vomiting, stool disturbances, pain in the stomach, inflammation of the oral mucosa, loss of appetite. The symptoms of pancreatitis and hepatitis may worsen.
From the central nervous system: convulsions, headache, dizziness. Hallucinations, mental disorders, and even depression may occur. Gait is often disturbed and disorientation in space and tremors of the limbs appear.
Circulatory system. In some cases, the development of leukopenia is observed, which is a good reason for developing a new drug treatment regimen.

According to the instructions, Mikozhinax suppositories, the price of which is relatively low, in case of overdose provoke the development of an allergic reaction in the form of all kinds of skin rashes, hyperemia, skin itching and, in severe situations, Quincke's edema or anaphylactic shock.

In addition, patients may experience the following conditions during treatment:

dark brown coloration of urine;
blurred vision;
the appearance of hallucinations;
frequent dizziness;
disorder of movement coordination, balance.

Special instructions for the use of candles

The reason for discontinuing treatment based on Mikozhinax is not menstruation. When using candles, it is recommended to use intimate hygiene products with a neutral or alkaline pH. During this period, women and girls should give preference to wearing cotton underwear.

When treating with a gynecological drug, it is prohibited to use hygienic tampons and have sexual intercourse. In the process of getting rid of vaginitis, treatment should be developed simultaneously for both sexual partners. While taking Mikozhinax, you should refrain from driving and limit work with potentially dangerous and precision devices.

Interaction

You should not simultaneously use Mikozhinax with the following substances:

Alcohol and drugs, because the likelihood of a disulfiram-like reaction (fear of death) is high. Drinking alcohol is allowed no earlier than one day after the administration of the last vaginal suppository.
“Cyclosporine” or creatinine, with an increased concentration of which in the blood plasma the state of health worsens.

An interesting fact is that the drug can reduce the strength of latex contraceptives, which significantly increases the risk of conception.

Pregnancy and lactation period

How to treat vaginitis that occurs during pregnancy and lactation? Definitely, “Mikozhinax” is not prescribed by gynecologists during breastfeeding and pregnancy. If you still cannot do without Mikozhinax during treatment, then breastfeeding should be suspended for this period.

Store the medicine in a cool place out of the reach of children. The ambient temperature should not be more than 25 degrees. Candles should be stored no more than three years after the date of manufacture.

Analogs

Drugs with similar effects are considered:

"Terzhinan" is a combination drug that has a trichomonacid effect. The antibiotic has a detrimental effect on pathogenic microorganisms and fungi of the genus Candida.
"Neotrizol" is an antibacterial drug that is able to penetrate the structure of a pathogenic cell and block protein synthesis.
"Cervugid" is an excellent analogue of "Mikozhinax" suppositories, which is used to treat vaginitis and cervicitis. The drug has an antimicrobial and antiseptic effect.
Metrogyl suppositories, which have antiprotozoal and antimicrobial effects, are used to treat infectious gynecological diseases. The main active ingredient is metronidazole. Metrogyl suppositories are almost completely absorbed after administration.

To avoid the appearance of vaginitis, it is important to be faithful to your sexual partner, use reliable methods of contraception, and also regularly perform genital hygiene.

Source: https://FB.ru/article/412682/svechi-mikojinaks-instruktsiya-pokazaniya-k-primeneniyu-sostav-analogi