Instructions for use
A complete list of pharmacological properties, compositional features and indications for the use of Pentalgin Extra Gel are described in detail in the instructions.
Separate paragraphs contain information about contraindications, age restrictions, special instructions and drug interactions of the drug with other pharmaceuticals. The scheme for using the gel contained in the instructions is standard.
pharmachologic effect
The action of Pentalgin Extra Gel is aimed at suppressing a certain group of enzymes involved in the synthesis of prostaglandins . The result of using the drug is an analgesic effect.
Additionally, the medication has an anti-inflammatory and anti-edematous effect, but the gel is not able to completely eliminate the inflammatory process on its own. The drug is highly effective in the symptomatic treatment of pathologies of bones, cartilage and joints.
Pharmacological properties:
- reduction of tissue swelling;
- eliminating joint stiffness in the morning;
- reduction of joint swelling due to bruises and inflammatory processes;
- relief of pain symptoms of inflammatory processes.
Indications for use
Pentalgin Extra Gel is intended to relieve pain in joints and bones caused by various factors..
The drug is used as part of complex therapy for pathologies of the musculoskeletal system (inflammatory processes, degenerative diseases). As a means of quick relief, the medication can be used for injuries and during exacerbation of chronic joint diseases.
Indications for use:
muscle pain of rheumatic origin;- sciatica and lumbago;
- exacerbation of chronic pathologies of the musculoskeletal system;
- osteochondrosis and osteoarthrosis;
- chronic diseases of the musculoskeletal system;
- bursitis and radiculitis;
- period of exacerbation of gout;
- muscle pain caused by injuries or sprains;
- post-traumatic inflammatory processes in tissues.
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Mode of application
Pentalgin Extra Gel is intended for external use . A small amount of the drug is applied to the painful area two or three times a day. The procedure is carried out with light massage movements.
Do not apply the gel to the skin if there is any damage (scratches, manifestations of dermatological diseases, open wounds). Otherwise, severe irritation may occur, accompanied by itching and burning.
Application nuances:
- The gel should be applied to clean skin;
- during the procedure, it is necessary to prevent contact of the product with the mucous membranes;
- a characteristic transparent film may form on the skin after applying the product;
- the drug cannot be used to make medicinal dressings;
- the maximum duration of the therapeutic course should not exceed two weeks.
Release form and composition
Pentalgin Extra Gel is available in the form of a transparent or translucent gel with a yellowish or red-brown tint. The drug is placed in a tube of 30 or 50 g and additionally sealed in a cardboard box. The gel has a characteristic menthol odor.
The active ingredient in its composition is ketoprofen . The substance provides the main pharmacological properties of the drug. The composition of the drug has been supplemented with auxiliary components that improve the process of penetration of the drug to the pain site.
Excipients:
- hypromellose;
- purified water;
- capsicum tincture;
- ethanol;
- dimexide;
- peppermint oil;
- sodium hydroxide;
- camphor.
Interaction with other drugs
The use of Pentalgin Extra Gel involves some special features. When combining the drug with certain pharmaceuticals, side effects may occur.
If the medication is used as part of complex therapy, then a doctor must draw up a treatment regimen. By supplementing the gel with certain drugs, it is possible to increase its effectiveness and accelerate the patient’s tendency to recovery.
Features of interaction with other tools:
- the gel enhances the toxicity of methotrexate-based medications;
- the drug should not be used in combination with other NSAIDs;
- It is not recommended to combine the medication with glucocorticoids and products containing ethanol;
- When taking coumarin anticoagulants, regular monitoring of laboratory tests is necessary.
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Expert opinion
Lyudmila Sheveleva, pharmacist
The use of Pentalgin quickly improves physical condition. This becomes possible by stopping inflammatory processes in the joints and spine. Thanks to the accelerated restoration of damaged capillaries and strengthening of the walls of blood vessels, hematomas resolve. The drug for external use rarely provokes the development of adverse reactions and is not addictive. But the list of contraindications for Pentalgin is quite wide. Therefore, before carrying out gel treatment, you should consult with an orthopedist, rheumatologist or neurologist.
Side effects
When Pentalgin Extra Gel is used correctly, side effects occur in rare or isolated cases. A common cause of an undesirable reaction of the body is ignoring the list of contraindications (including applying the gel to damaged areas of the skin).
Allergic manifestations to the drug are provoked by hypersensitivity to ketoprofen or other substances from NSAIDs.
Other side effects:
- contact dermatitis;
- exacerbation of renal failure;
- bullous type dermatitis;
- urticaria symptoms;
- anaphylactic reactions;
- respiratory dysfunction;
- peptic ulcer.
Overdose
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Next fact
Systemic absorption of ketoprofen is low. This nuance practically eliminates the occurrence of side symptoms caused by an overdose of Pentalgin Extra Gel .
The exception is violation of the dosage regimen in the presence of contraindications. The consequence of applying too much gel to the skin will be increased side effects. A tendency to allergy to NSAIDs may occur due to too long or frequent use of the drug.
Contraindications
Pentalgin Extra Gel is contraindicated in patients with a known allergy to non-steroidal anti-inflammatory drugs (allergic rhinitis, skin rash, history of respiratory disorders).
The drug should not be used during periods of exacerbation of dermatological diseases accompanied by damage to the skin (eczema, weeping dermatoses).
The medication is prohibited for use by pregnant women and children.
Other contraindications:
- tendency to allergic reactions to perfumes or skin care products;
- hypersensitivity to ketoprofen or other components of the medication;
- bronchial asthma (especially in combination with intolerance to NSAIDs);
- intolerance to acetylsalicylic acid.
During pregnancy
Pentalgin Extra Gel is not suitable for treating pregnant women . Ethanol, herbal tinctures and other components of the drug may cause unwanted reactions in the fetus.
During the lactation period, the use of the medication is permitted only if breastfeeding is temporarily stopped. Otherwise, the newborn baby may experience allergic manifestations or disruption of the functioning of some internal systems.
special instructions
Impact on the ability to drive a car and operate machinery
NSAIDs for external use do not affect psychomotor reactions. If the patient’s general condition is not accompanied by impaired concentration, then operating machinery or a car can be carried out as usual.
Application in pediatric practice
Contraindication for the use of the medication is age under eighteen years. In children, components of the drug may cause adverse symptoms (including allergic reactions).
For kidney problems
Severe renal pathologies are the basis for adjusting the gel dosage regimen. The drug is used in minimal quantities. If laboratory test data changes, the medication may be discontinued according to indications.
For liver disorders
Severe liver pathologies are the basis for careful use of the gel. If the patient's condition worsens or adverse symptoms occur, the drug must be discontinued.
Conditions for dispensing from pharmacies
You do not need a prescription to purchase NSAIDs at pharmacies.
Analogs
A distinctive feature of Pentalgin Extra Gel is the maximum concentration of ketoprofen in its composition. This nuance explains the high effectiveness of the drug in relieving pain.
The effect of medications with a lower content of ketoprofen or the absence of this substance in the composition may be inferior to Pentalgin Extra Gel.
When selecting analogues, it is recommended to pay attention to possible differences in the lists of contraindications, dosage regimens and other points of the instructions.
Examples of analogues:
- Artrosilene (430 rubles);
- Ketoprofen (from 80 rubles);
- Ketonal (from 300 rubles);
- Febrofid (400 rubles).
Composition and release form
The active main substance, ketoprofen, blocks the activity of enzymes that affect the synthesis of anti-inflammatory, destructive agents: prostaglandins, leukotrienes, thromboxanes. The active work of bradykinins and neutrophils decreases, which helps eliminate inflammation.
The product contains auxiliary elements:
- Tincture of capsicum fruits and camphor have a slight warming effect.
- Dimethyl sulfoxide (Dimexide) increases the penetration of drug components through the skin.
- Peppermint leaf oil improves blood flow and eliminates muscle fatigue.
- Hypromellose has a pronounced protective and softening effect.
Pentalgin also contains sodium hydroxide, ethanol 96%, purified water. The drug is absorbed very slowly from the area of application and does not accumulate in the body.
The medicine is produced in aluminum tubes with a capacity of 30 g, 50 g or 100 g. Packaged in cardboard boxes with instructions for use. Liniment has a transparent or translucent texture with a characteristic odor. Color ranges from yellowish brown.
If there are air bubbles in the gel, this does not affect the quality - you can use it.
