Candid-B6 - instructions for use of vaginal tablets, indications, side effects, analogues and price

• January 13, 2021
• obstetrics and gynecology
• Ulyana Romanova

"Candide B6" is a broad-spectrum antifungal agent intended for topical use. In what form does it come? How does it work? And for what conditions is it prescribed? You will find answers to the most important questions regarding this medication from the article.

Candid-B6 - instructions for use

This drug is used to suppress fungal infections in the vagina. Comprehensively fights bacteria, trichomonas. It is important to adhere to the course prescribed in the instructions for use, otherwise regular recurrence of diseases will occur. The medicine is extremely effective against the fungi Malassezia furfur, Trichomonas vaginalis (Trichomona vaginali), Corynebacterium minutissimum.

Composition and release form

The drug Candide B6 is available in the form of vaginal suppositories (suppositories) without a white shell, oval, biconvex shape. On one side there is a sign V6, on the other there is a letter G. The package contains one strip of 6 capsules complete with an applicator. The active substance is clotrimazole, which occupies 99% of the mass of the suppository. The remaining substances are intended to create form and better absorption.

pharmachologic effect

The substance clotrimazole, a derivative of imidazole, disrupts the formation of ergosterol, an element that is one of the key elements for the formation of the fungal membrane. The drug successfully suppresses and destroys yeast, mold fungi, dermatophytes, pathogens of pityriasis versicolor and erythrasma, gram-negative and gram-positive bacteria. It is important to remember that the correct treatment and dosage of medication can only be prescribed by a doctor after laboratory tests.

Indications for use Candid-B6

The use of medicine in suppositories makes sense for fungal genital infections provoked by yeast-like fungi of the genus Candida or Trichonoma vaginalis (trichomoniasis, vulvovaginal candidiasis). Also prescribed for vaginal superinfections caused by bacteria susceptible to the drug. The drug Candid-B6 is prescribed for sanitation of the birth canal immediately before childbirth to exclude possible candidiasis in the child.

Release form and composition

The product “Candide B6” is produced in the form of vaginal white tablets without a coating. They are biconvex, oval, truncated on one side, and have an o.

One tablet contains 100 mg of the active substance, which is clotrimazole. The auxiliary components include talc, adipic acid, propyl parahydroxybenzoate, povidone, corn starch, silicon dioxide and several other compounds.

The average cost of a package with six such tablets is about 60-80 rubles.

Directions for use and dosage

The Clotrimazole suppository is inserted into the vagina in the evening as deeply as possible. The standard course involves daily use of all 6 suppositories (single doses) from the package. Possible repetition of treatment is prescribed by the doctor. When sanitizing the birth canal before childbirth, one suppository is used. Rules for using the capsule applicator (one dose, duplicated in the instructions):

1. Pull out the applicator piston as much as possible and put the suppository (tablet) inside.
2. Lie on your back and bend your knees slightly.
3. Carefully insert the applicator as deep as possible into the vagina.
4. Slowly press the plunger all the way to insert the tablet.
5. Remove the applicator smoothly, without jerking.
6. After use, wash the device with soapy warm water (completely disassemble first) and wipe dry.

Treatment with Candide

1. For women, suppositories or tablets against fungus are recommended as a local treatment. A single administration of the drug in a volume of 500 mg before bedtime. The duration of treatment is determined by the doctor, as well as the need for a second course. Reviews from patients using Candida indicate the effectiveness of using the drug, especially in the acute form of the disease.
2. Candida cream can also be used in the treatment of fungus.

   
   Cream Candide
   It is used to lubricate the affected areas where pronounced symptoms of thrush are observed. On average, the cream is used twice a day, but there may be individual characteristics of the course of the disease when the frequency of use of the cream increases.

3. Candide is also available in powder form. It is used in the same way as a cream, applied to inflamed areas. The duration can be up to a month. In the initial period of treatment, the frequency of use is up to three times a day, then it should be used once a day. The course of treatment is carried out under the supervision of a specialist.
4. Since the drug Candide contains the active substance Clotrimazole, possible contraindications and increased sensitivity of the body to the components of the drug should be taken into account.

   
   Candida powder
   Before starting treatment, you should consult your doctor. Similar effects from the use of the drug Candide can be in the form of allergic reactions, swelling or burning. Reviews of the drug indicate that such reactions can occur in people suffering from various types of allergies.

5. The drug Candida is prescribed for gynecological problems in women associated with the activity of the Candida fungus and is most often used as suppositories or vaginal tablets. To verify the effectiveness of the drug, you can read the reviews of those who have already used the drug for thrush.

Reviews from patients about the use of the drug Candide

Svetlana, 23 years old: “I encountered thrush for the first time and didn’t know what to do. Of course, among my friends there were those who had already had thrush, so I tried to find out from them who should be used to eliminate the symptoms of the disease. The discharge was very strong and the itching was constant, my head and stomach began to hurt, perhaps this was due to constant discomfort. There was a lot of advice, I didn’t know what to use, but as a result I made an appointment with a gynecologist. They took tests there, but the doctor first said that it was definitely thrush. This is what happened according to the test results. I was prescribed local treatment with Candide B6 in the form of suppositories. These are not quite ordinary suppositories; they are called vaginal tablets. They are quite easy to administer because there is an applicator that helps you insert the tablet correctly. First you need to moisten it with water so that it dissolves a little. I did the procedure in the evening, and in the morning there was almost no itching or itching. We can say that it was simply a miracle for me, after the torment I endured. On the doctor’s recommendation, I did the procedure for a few more days as a preventive measure. At the same time, I also took pills for both treatment and prevention. I can’t say how other drugs work, but this one definitely helped me.”

Natalya, 34 years old: “I met a thrush a year ago. She was treated several times, with different drugs, but after a while the thrush came back. Maybe I didn’t treat it completely, maybe the drugs were wrong. Once again I went to the antenatal clinic, again with the same problem. This time I was prescribed Candide tablets. The most interesting thing is that they are quite cheap compared to other drugs. At first I thought that there would be no effect, but surprisingly, already on the second day, it became much easier, one could even say that the main unpleasant sensations disappeared. Since my disease is chronic, the course had to be carried out within a week. I did everything, I also did douching, washing and other procedures so that the inflammatory processes would disappear faster. I also took a pill, also for prevention. As a result, the candles helped a lot. The symptoms have disappeared, nothing worries me. I really hope that the disease will not happen again in the near future.”

Veronica, 25 years old: “I heard a lot about treating thrush with Candide suppositories, and since I myself encountered this problem, I decided to try this remedy on myself. I used vaginal tablets at night. Two days later, all signs of the disease disappeared. The product, although cheap, is effective. It might even be better than expensive analogues.”

Irina, 30 years old: “I got sick with the flu, was treated with antibiotics, and then suddenly discovered that I had thrush. I had to go to the gynecologist to have tests taken and treatment prescribed. As a result, the doctor prescribed me Candide B6 tablets for insertion into the vagina. I had never heard of this drug before; I knew about some antifungal agents from numerous advertisements. And then it turned out that there was a cheap and good treatment. In one go, the discomfort disappeared. I began to feel like a human being. In addition to treating the thrush, it was also necessary to restore the immune system, so I took medications to restore the flora after the flu, apparently this became the cause of the thrush. Now I feel that my body is normal. You don't have to worry anymore. I recommend it to anyone who wants to quickly cure a disease, but it’s still better to go to the doctor first to have an examination. Specialists know what is needed specifically in your case.”

Source: https://molochnitsa.com/lechenie-molochnicy/preparatami/svechi-kandid-ot-molochnicy.html

special instructions

To fully treat candidiasis and avoid reinfection, both partners must take Clotrimazole at the same time (for men there are forms in the form of creams, ointments, tablets). The use of vaginal suppositories during menstruation is not recommended. During treatment, you should refrain from sexual intercourse and use other intravaginal products (tampons, spermicides, etc.) is prohibited. Taking Candide B6 suppositories orally is prohibited (from a treatment point of view, it is useless).

In parallel with Candida B6 (Clotrimazole), it is recommended to use systemic drugs, for example, Metronidazole, for trichomoniasis. If candidiasis vulvitis is present, then vaginal suppositories are supplemented with external application of Candida cream. Patients with liver failure should monitor their liver condition. At the first signs of irritation or hypersensitivity, stop taking the drug. It is better to consult a doctor.

Reviews

Doctors say that they often use Candide B6 in their practice. This is an effective, easy to use, affordable drug that very rarely causes unwanted side reactions. In addition, it copes with candidiasis quickly.

Women also respond positively to the pills. Of course, many of them note the unpleasant sensations that arise during the procedure. Tablets, unlike conventional candles, do not have any shell, and therefore do not create additional lubrication.

But in six days you can really get rid of thrush, including chronic ones (in the second case, with the use of additional medications in combination, of course).

But unpleasant symptoms, by the way, begin to disappear by the end of the second day from the start of using the tablets. Your health is improving, and therefore you may want to stop using the drug, but this is strongly not recommended! Because in the first days the symptoms only stop - a deep and thorough effect on the cause of the disease develops a little later.

Candid-B6 during pregnancy

The drug is contraindicated in the first trimester of pregnancy. In the second and third, use only as prescribed by a doctor. At this time, it is necessary to adjust the dosage of the drug based on the tests of the expectant mother. When using Clotrimazole for sanitation of the birth canal, you should handle the applicator with extreme caution. The effect of the drug during breastfeeding is unknown, since no studies have been conducted on the penetration of the active substance into mother's milk.

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Pharmacodynamics

Now you can delve deeper into the study of the instructions for the Candide B6 candles. This remedy has antiprotozoal, trichomonacid, as well as antibacterial and antifungal effects.

The drug has a wide spectrum of activity due to its active substance. Clotrimazole is an imidazole derivative. It disrupts the synthesis of ergosterol, which is a component of the cell membrane of fungi. This leads not only to a change in its structure and properties, but also to cell lysis.

The medication can affect many microorganisms. In high concentrations, it can even infect Trichomonas vaginalis. But clotrimazole is still not omnipotent, and there are microorganisms that are resistant to it. For this reason, the doctor always first examines the patient’s tests, identifies the causative agent of her disease, and only then determines the effective drug.

Drug interactions

The use of other intravaginal and conventional drugs will significantly reduce the therapeutic effect of Clotrimazole (Candide B6). Candide B6 creates an inhibitory effect for polyene antibiotics (Amphotericin B). It is strictly not recommended to combine different intravaginal medications or different antifungal drugs during one course.

Candide B for nail and foot fungus (on the legs)

The use of topical antifungal agents, which include Candide B, has its considerable advantages. They do not enter the bloodstream, which means they have fewer side effects. Often the choice in favor of such drugs due to their safety is made by pregnant and lactating women, as well as elderly people.

Description

Candide B is a topical antifungal anti-inflammatory drug. The cream is used externally only, and is effective against itching and to relieve other eczematous symptoms. If there is no reaction, it can also be used to treat the mucous membranes of the skin.

The active ingredients in the drug are beclomethasone and clotrimazole. Both of these drugs are not antibiotics; clotrimazole has an antifungal effect, beclomethasone is a glucocorticosteroid. Therefore, Candide B is not an antibiotic.

• At the same time, the content of the glucocorticosteroid component (beclomethasone) in the medication indicates that it is hormonal.
• The drug is a topical drug, so eating does not affect its effect.
• Refers to over-the-counter medicines.
• The ointment is not prescribed during menstruation in the early stages of pregnancy.
• There is no scientific data on the use of Candide B in HIV-infected people; the decision on its use in patients with immunosuppression is made by the doctor.

IMPORTANT! When used vaginally, clotrimazole affects the effectiveness of Amphotericin B and a number of other polyene antibiotics.

Candide B is available in only one form of release - as an ointment with an active substance concentration of 1%, in tubes weighing 15 g.

Manufacturers

On the Russian pharmaceutical market, the original Candide B is represented by only one manufacturer - the Indian company Glenmark Pharmaceuticals Ltd.

Indications for use

The drug is used for fungal skin diseases and relieves acute eczematous manifestations well.

Indications for the use of Candida B are:

• microsporia of smooth skin;
• athlete's foot;
• microsporia;
• candidiasis of the genital organs and skin;
• mycoses.

Source: https://www.GribkuNet.ru/medicinskie-sredstva/kandid-b.html

Side effects

Standard side effects (allergic reactions) occur due to personal intolerance or interaction of Clotrimazole with other drugs. In addition, different manifestations of negative consequences are possible depending on the general condition of the patient. If the following side effects from Candide B6 occur, you should consult a doctor and, if necessary, stop the course:

• peeling of the skin on the genitals;
• swelling;
• vaginal bleeding;
• discomfort;
• elevated temperature;
• frequent urge to urinate;
• pain in the lower abdomen;
• arterial hypotension;
• itching;
• hives;
• dyspnea;
• disturbances of consciousness (loss of coordination).

Adverse reactions

“Candide B6” rarely has side effects, but nevertheless, they are listed in the instructions for use, and therefore every patient should know them. The list is as follows:

• Headache.
• Swelling and burning of the vaginal mucosa.
• Pain during sexual intercourse.
• Itching.
• Cystitis of intercurrent type.
• Gastralgia.
• Various discharges.
• Increased urination.
• A burning sensation in the sexual partner.

This medication does not cause any conditions that could be life-threatening. The main thing is to never take Candide B6 orally. Because this can lead to the development of anorexia, severe nausea and vomiting, as well as gastralgia, liver problems, hallucinations, drowsiness, allergies and pollakiuria.

And at a minimum, this is fraught with poisoning, in which the patient is given activated charcoal and then given symptomatic treatment.

Analogs

Substitute drugs belong to the ATC level 4 code. Replacement of Candide B6 is required in case of persistent individual sensitivity or non-acceptance of the drug, when the body does not respond to the use of the drug. Analogues of Candida suppositories can be vaginal tablets or oral medications that do not contain Clotrimazole (in cases of allergy to the substance). What is the drug replaced with:

• Clotrimazole Acri;
• Clotrimazole Akrikhin;
• Lotrimin;
• Faktodin;
• Fungiciple.

Alternative drugs

Now we can discuss the analogs available for Candide B6 tablets. You can pay attention to the following medications:

• "Kandibene". These are also white, oblong-shaped vaginal tablets, each containing 200 mg of clotrimazole.
• "Canesten." The drug has a pronounced antifungal effect. There are tablets with varying amounts of clotrimazole, the maximum being 500 mg. The product is also available in spray form.
• "Candisan." Each tablet contains 100 mg of active ingredient.
• "Clotrimazole". Complete analogue of the previous drug.

There are not so many vaginal tablets for candidiasis. But there are other forms of release - for example, candles, sprays, creams, solutions. There are also medicines that are simply similar to Candide B6 in terms of their effects - these are Canison, Magne B6, Candide, Pyridoxine, Biotredin, Lizobact, Metadoxil and dozens of other medicines.

Often the use of one drug is complemented by another. However, the therapeutic regimen is prescribed to the patient individually by the doctor - only he will be able to determine which remedy and in what form will be effective for her.

Contraindications

Candide B6 is contraindicated in patients with hypersensitivity to clotrimazole and beclomethasone.

The drug is not used in treatment during pregnancy in the 1st trimester and during the lactation period.

Intravaginal forms cannot be used during menstrual flow.

Candide B6 is not prescribed in pediatric practice. The drug is approved for children over 12 years of age.

Photo gallery of contraindications:

Increased sensitivity

1st trimester of pregnancy

Menstruation

Lactation Children under 12 years of age

Price of the drug in pharmacies