Friendly parties, holidays, corporate meetings, and feasts are rarely complete without strong drinks. Alcohol allows you to relax and immerse yourself in a relaxed atmosphere. However, it is insidious in that it quickly becomes addictive and dependent, which can develop into such a common disease today as alcoholism.
Frequent consumption of alcohol-containing products leads to liver damage.
During the treatment process, specialists attach particular importance to the restoration of organ functions and use Metadoxyl, an effective modern medicine, for this purpose.
Mechanism of action
The drug has a hepatoprotective effect, which is expressed in restoring the balance of saturated and unsaturated fatty acids, which stabilize the functioning of liver cells . Under the influence of the active substance, cells become resistant to the lipid oxidation reaction that occurs when ethanol acts on the fatty membrane of the cells.
The drug activates the production of liver enzymes that decompose ethanol and promotes the rapid removal of its residues from the body. As a result of the action of the drug, the balance of fatty acids is normalized, which promotes the restoration of liver cells and prevents its destruction. Metadoxil reduces the craving for drinking alcohol and alleviates hangover syndrome. The drug reduces the risk of developing liver cirrhosis.
Under the influence of metadoxine, the effect of ethanol on the cells of the cerebral cortex and the nervous system is reduced. As a result, the patient reduces the manifestation of the mental and physical consequences of the hangover syndrome in the form of headaches, nausea and vomiting, dizziness , increased anxiety, pain in joints and muscles.
As a result of using Metadoxil, patients' sleep normalizes, anxiety disappears, memory and attention improve. Metadoxine in this case is used as an antidepressant.
Instructions for use
The medicine is used strictly as prescribed by the doctor, who must examine the patient. The dosage, duration of treatment and the appropriateness of using the drug are carried out taking into account the age, physiological and individual characteristics of the patient.
Depending on the degree of acute alcohol intoxication, use 5-10 ml of the drug intramuscularly or 5-15 ml intravenously . Before intravenous use of the drug, it is first diluted with sodium chloride solution or glucose. The drug is administered intravenously over an hour and a half.
For the treatment of liver diseases, one tablet is prescribed twice a day before meals. The duration of use of the drug is at least 90 days.
When treating alcohol withdrawal syndrome, the drug is administered intravenously once a day for seven days. The duration of the course of use of the drug depends on the patient's condition.
The drug Metadoxine is not used for treatment during pregnancy, since the active substance is able to cross the placental barrier and can have a negative effect on the development of the fetus.
Metadoxil price
You can buy Metadoxil at the pharmacy. It is convenient for consumers to order medication delivery on the online store website. The cost of the drug depends on the form of release and packaging. Prices for the drug in Moscow pharmacies are shown in the table:
Name of the drug | Packing | Price (rubles) | Name of pharmacy chain |
Metadoxil, tablets 500 mg | 30 pieces | 1269 | Ver.ru |
Metadoxil, solution for injection 300 mg | 10 ampoules | 1031 | Hello zone |
Metadoxil, tablets 500 mg | 30 pieces | 1235 | Hello zone |
Metadoxil, tablets 500 mg | 30 pieces | 1316 | ZdravCity |
Metadoxil, solution for injection 300 mg | 10 ampoules | 1123 | Ver.ru |
Metadoxyl, solution for injection | 10 ampoules | 1172 | Pills.ru |
Contraindications and side effects
The use of the drug is prohibited for women during pregnancy and breastfeeding.
The use of the medicine is prohibited if the patient is diagnosed with the following diseases and pathological conditions:
- hypersensitivity to the components of the drug;
- Parkinson's disease, if Levodopa is used for treatment, which may reduce the effectiveness of Metadoxine;
A side effect of the drug may manifest itself in the form of an allergic reaction to the components of the drug. The tablets contain a component that can cause the patient to develop bronchospasm and an attack of bronchial asthma.
Some patients experience the appearance of urticaria, itching, swelling and hyperemia of the skin.
Additional Information
The main advantage of the drug is its harmlessness. It does not have a toxic effect on the human body if it reacts with ethanol or in case of overdose. The medicine is quickly absorbed from the gastrointestinal tract and excreted from the body within a day.
Among the disadvantages is a possible allergic reaction to the components of the drug. In this regard, patients are first administered a small dose of medication , and if there is no negative reaction from the body, the prescribed dose of Metadoxil is used.
Analogues and price of the drug
Due to the high price of the drug, many patients try to replace it with cheaper analogues.
To treat alcohol addiction, Lidevin is often used, the effect of which is based on the aversion to alcoholic beverages as a result of blocking liver enzymes. This remedy has a large number of contraindications and side effects.
Medichronal is an analogue that relieves withdrawal symptoms . The product eliminates intoxication and psychological cravings for alcohol.
The following analogues are also recommended for the treatment of the disease: Vokacit, Colme, Cyamide, Deltaran, Proproten.
The drug can be purchased at a pharmacy without a doctor's prescription or ordered from an online pharmacy. The average price for a package of medicine is from 1200 rubles.
Metadoxyl
Active substance:
Metadoxine
Pharmgroup:
Means for the correction of disorders in alcoholism, toxic. and drug addiction
Average price in pharmacies
Name | Manufacturer | average price |
Metadoxyl 0.3/5ml 5ml n10 amp solution d/in | Doppel Pharmaceutical S.r.L. | 1709.00 |
Metadoxyl 0.5 n30 tab | LABORATORY BALDACHI S.P.A. | 1748.00 |
Analogs for the active substance:No data on synonyms | Application area:Alcohol withdrawal syndrome Withdrawal syndrome Withdrawal syndrome in alcoholism Abstinence Alcohol withdrawal Alcoholism Alcohol withdrawal Alcohol adynamic depression Alcoholic hepatopathy Alcohol addiction Alcohol withdrawal state Alcoholic liver damage Alcoholic liver damage Alcohol withdrawal syndrome Alcohol delirium Alcoholic delirium tremens Delirium Delirious state in alcoholism and drug addiction Delirious state in alcoholism and drug addiction Depressive and anxiety-depressive states in patients with alcoholism Dipsomania Liver diseases of alcoholic etiology Alcohol addiction Binge drinking Drunken state Alcohol abuse Ideation disorder in alcoholism Quarterly binge Obsessive craving for alcohol Neurotic symptoms in alcoholism Pathological craving for alcohol Behavioral and post-withdrawal disorder in alcohol dependence Post-withdrawal disorder Post-withdrawal state Hangover syndrome Psychoorganic syndrome in chronic alcoholism Withdrawal syndrome Alcohol withdrawal syndrome Alcohol withdrawal syndrome Reduced craving for alcohol Withdrawal state Chronic alcoholism Cirrhosis of alcohol origin |
Patient reviews of Metadoxil
Reviews from doctors about the drug are positive. Most patients stop drinking alcohol completely; at the beginning of the course of treatment, their craving for alcohol disappears, side effects are reduced as a result of the use of complex treatment of the disease using Metadoxil.
Reviews from alcoholics about the drug note its high effectiveness, reduced cravings for alcohol, and relief of general physical condition in a short time.
There will be no result from using one tablet. Long-term treatment and patience are required. I have tried many medications over a long time. I took the medicine morning and evening as prescribed by the doctor. As a result, the liver began to bother me less and heartburn disappeared. The most important thing is that you don’t feel like drinking anymore. Now I can easily give up alcohol even at the holiday table.
Sergey
Metadoxil is an effective drug for protecting the liver and preventing alcohol dependence. I used it on the recommendation of a doctor as a medicine with few side effects. The first result is noticeable after two weeks. The craving for alcohol decreases. This medicine does not cure a hangover, but reduces its effects.
Oleg
He was treated for alcoholism in a rehabilitation center.
The doctor used Metadoxil. The drug really helps: the desire to drink disappears when you take the pills regularly. Konstantin
Indications
This drug in tablets and ampoules is indicated for people suffering from alcoholism.
Can be used for:
- eliminating symptoms of acute alcohol poisoning;
- reducing toxic damage to liver cells;
- treatment of old chronic alcoholism;
- relieving hangover syndrome;
- prevention of cirrhosis;
- reducing dependence on alcohol.