Category: Published 04/25/2017 · Comments: · Reading time: 5 min · Views: 4,727
An effective pharmacological agent based on a complex of vitamins from subgroup B - Neuromultivit tablets. What does the medicine help with? The drug has proven itself excellent in complex treatment tactics for many neurological pathologies. The instructions for use suggest taking the drug “Neuromultivit” for sciatica, neuralgia, and back pain.
Compound
Main active substances:
- thiamine hydrochloride (vitamin B1);
- pyridoxine hydrochloride (vitamin B6);
- cyanocobalamin (vitamin B12).
The quantitative ratio of vitamins in one tablet is:
- B1 – 100 mg;
- B6 – 200 mg;
- B12 – 0.2 mg.
The composition includes additional substances:
- povidone;
- microcrystalline cellulose;
- macrogol 6000;
- magnesium stearate;
- talc;
- hypromellose;
- titanium dioxide (E 171);
- 30% polyacrylate dispersion.
pharmachologic effect
The properties of the three main components determine the pharmacological action of the drug. The complex contains all B vitamins:
- improve metabolic processes in nerve tissues;
- increase the tissue regeneration ability of nervous system cells;
- provide a mild analgesic effect.
The vitamin complex has the following effects:
- normalizes regenerative processes in nervous tissue;
- stimulates the metabolism of the nervous system;
- has an analgesic effect.
Neuromultivit is recommended to be taken as part of complex therapy.
"Milgamma" or "Neuromultivit" - which is better?
"Milgamma" is exactly the same preparation of B vitamins. It is produced in the form of ampoules with a solution for injection and in the form of tablets for oral use. The use of ampoules is more effective, since with the injection form of administration the components are absorbed almost one hundred percent. When taken orally, vitamins may not be fully absorbed.
“Milgamma” or “Neuromultivit” - what should a patient choose who has not yet tried any of these medications? The composition of Neuromultivit is almost completely identical to the composition of Milgamma. They are also approximately the same in cost - a package of both tablets will cost about eight hundred rubles. All that remains is to rely on the prescription of the attending neurologist - the drug that was prescribed will be more effective in each individual case.
Pharmacodynamics of the drug
The product contains a combination of neurotropic active substances of the vitamin B complex:
- Thiamine. The human body accumulates up to 30 mg of vitamin B1. Given the rapid metabolism, the reserve is limited and is used up within a week.
- Pyridoxine. Absorption of the substance occurs instantly in the upper gastrointestinal tract. Vitamin B6 is excreted in urine within a few hours.
- Cyanocobalamin. Absorption of vitamin B12 occurs under the influence of gastric juice and due to passive entry into the bloodstream. The substance accumulates mainly in the liver and is excreted in bile.
Vitamins B1, B6 and B12 are low toxic and do not pose a risk to the patient. Insufficient intake of vitamins from food is compensated by the therapeutic introduction of B vitamins into the body. Taking the complex ensures the presence of the required amount of coenzymes in the body.
The use of the drug for pathologies of the nervous system compensates for vitamin deficiency and stimulates natural recovery mechanisms.
For pyridoxine deficiency
Pyridoxine hydrochloride is one third of the composition of Neuromultivit. This is vitamin B6, the main effect of which is on the nervous system. With pyridoxine deficiency, the following conditions develop:
- anxiety, tearfulness;
- hypochondria (especially common in older people);
- memory impairment;
- regression of cognitive abilities;
- imbalance of sodium and potassium in the body;
- chronic fatigue and constant feeling of overwork (even after eight hours of sleep).
With pyridoxine deficiency, the patient is characterized by aggression and motor overexcitation. This process is caused by the fact that the adrenal glands begin to produce adrenaline more intensively. Glucose reserves in the body begin to rapidly decrease, and sugar reserves, on the contrary, increase. As a result of this condition, various types of depression can develop.
An excess of pyridoxine also does not bring anything good. The side effects of Neuromultivit are largely due to the fact that with regular use of the drug, hypervitaminosis of this substance occurs. Here are the symptoms of increased levels of pyridoxine in tissues:
- numbness of the limbs;
- nervous tics;
- allergic rashes, dermatitis and urticaria;
- skin itching;
- indigestion - diarrhea.
Indications for use
Neuromultivit tablets are indicated for use in the following pathologies:
- lumbar syndrome (lumbago);
- damage to the facial nerve (prosoplegia);
- plexitis of the cervical and brachial plexuses;
- sciatica;
- trigeminal neuralgia;
- radicular neuritis of the spine;
- intercostal neuralgia.
Before starting treatment for neuritis and neuralgia, it is recommended to consult a neurologist. Indications for use as complex therapy may include atopic dermatitis and psoriasis.
Advantages of Neuromultivit
Pregnancy is a biological process that changes many chemical reactions in the body. The body of the expectant mother prepares for childbirth and undergoes many changes. The drug Neuromultivit can be used during pregnancy for various neurological disorders in order to eliminate the symptoms of the disease and provide the necessary support to the nervous system. Neuromultivit tones muscle tissue and provides the necessary level of protection to nerve cells.
The combined Neuromultivit complex stabilizes the nervous system, which is important during pregnancy. B vitamins are necessary to eliminate the symptoms of polyneuropathy, inflammation of the sciatic nerve, and osteochondrosis. If such pathologies are present in the expectant mother, they must be corrected with the help of drug therapy. Lack of treatment during pregnancy can cause irreparable harm to the fetus.
Contraindications
The main contraindication when taking the drug Neuromultivit is hypersensitivity to one of the components. The following facts should be taken into account:
- Vitamin B1. In case of allergic reactions, it is prohibited to take this substance.
- Vitamin B6. The component is contraindicated for gastric and duodenal ulcers in the acute stage due to a possible increase in the acidity of gastric juice.
- Vitamin B12. In case of thromboembolism, erythremia or erythrocytosis, the patient should not take this substance.
If you have chronic diseases, you should consult a therapist about taking Neuromultivit tablets or injections. Due to the lack of clinical studies, the use of the drug in children and adolescents is contraindicated.
Neuromultivitis for children
To date, the safety of the drug for children under 12 years of age has not been clinically proven. There is an opinion that when this drug is prescribed to small patients, they develop hypervitaminosis, which is extremely important to prevent in a child. Hypervitaminosis develops due to the fact that the drug contains B vitamins, the daily dose of which is intended only for adults. However, there are cases where pediatricians still prescribe analogue drugs to children over 3 years of age. The pediatrician tries to take into account all the individual characteristics of the child and the clinical case.
After a thorough examination of the child and collection of a detailed, reliable history, the doctor decides on the advisability of prescribing the drug.
Side effects
The vitamin complex Neuromultivit is normally tolerated by the body. In isolated cases, there is a small likelihood of side effects associated with long-term use of large doses of the drug. Disturbances may appear from the gastrointestinal tract:
- nausea;
- diarrhea;
- abdominal pain;
- gagging.
The following disorders are suspected from the central nervous system:
- dizziness;
- fainting;
- the appearance of tinnitus;
- headache;
- excessive sweating;
- arrhythmia;
- weakness.
In case of individual intolerance to one of the components of the drug, the following negative symptoms are observed:
- erythema;
- hives;
- redness of the skin;
- itching
Such changes occur in rare cases after therapy lasting more than a month. There is a small chance of an anaphylactic reaction.
Signs of cyanocobalamin deficiency and overdose
Cyanocobalamin plays an important role in the process of hematopoiesis; without it, healthy immunity and well-being are impossible.
Signs of cyanocobalamin deficiency in the body:
- frequent colds, weak immunity;
- furunculosis, dermatitis, eczema, psoriasis, acne;
- constant lethargy, weakness, low vitality;
- drowsiness and chronic fatigue;
- characteristic changes in the general blood test - low number of red blood cells;
- stuttering and speech development disorders;
- unpleasant odor from the patient's skin;
- dizziness and headaches, memory problems, irritability;
- sexual dysfunction in men.
But an excess of cyanocobalamin does not bring anything good. The side effects of Neuromultivit are largely due to the fact that with regular use of the drug, hypervitaminosis of vitamin B12 occurs.
Characteristic symptoms that a person has an excess of cyanocobalamin in the blood and internal organs:
- thrombosis;
- chills, tremors of extremities;
- cramps of the ankles, calf muscles, feet;
- sleep problems;
- nausea, hyperemia;
- dermatitis, urticaria.
The daily requirement for cyanocobalamin in an adult is about 2-3 mcg. In pregnant women, this figure doubles, since cyanocobalamin is required not only by the mother, but also by the fetus.
Compatibility with other drugs
No dangerous interactions or incompatibility were found with most medications during clinical studies. But doctors do not recommend taking Neuromultivit simultaneously with other multivitamin medications.
Drinking alcoholic beverages negatively affects the intake of the vitamin complex, reducing the effectiveness of the components’ effects on the body. It is recommended to abstain from alcohol for the entire period of therapy.
When taking Neuromultivit and Levodopa simultaneously, a decrease in the effectiveness of the latter remedy is observed.
special instructions
Vitamin B1 decomposes in the presence of sulfite-containing solutions. In the presence of thiamine breakdown products, the effect of other vitamins may be reduced.
Vitamin B1 is incompatible with oxidizing and reducing compounds, for example, with iodides, carbonates, acetates, ferric ammonium citrate, tannic acid, dextrose, phenobarbital, disulfites, riboflavin, benzylpenicillin.
Vitamin B1 is destroyed more quickly in the presence of copper; In addition, the effect of the vitamin disappears if the pH value increases (more than 3).
When taken together, vitamin B6 in therapeutic doses may reduce the effect of levodopa.
Possible interaction with drugs such as cyclosporine, penicillamine, isoniazid, epinephrine, norepinephrine, sulfonamides.
Vitamin B 12 is incompatible with heavy metal salts. Riboflavin has a destructive effect, especially with simultaneous exposure to light; nicotinamide accelerates photolysis, antioxidants have an inhibitory effect.
The drug is administered exclusively intramuscularly; it must not enter the blood vessels.
In case of accidental intravenous administration, medical supervision (in a hospital setting) is required, which depends on the severity of the symptoms encountered.
Use of the drug
According to the instructions, you should take the vitamin complex after meals. The tablets must not be chewed; they must be taken with a small amount of liquid.
The recommended dose is 1 tablet per day. The maximum daily dose, if necessary, is 3 tablets, divided into three doses. The dosage is determined separately in each case.
The duration of the therapeutic course is determined by the attending physician according to the needs of the patient. The treatment period is 4 weeks. Taking the drug for more than a month in large doses often provokes neurological symptoms. After this period, the therapist makes a decision to adjust the dosage of the drug.
Drinking alcoholic beverages and strong tea reduces the absorption of thiamine. Drinking wine that contains sulfites increases the degradation of thiamine.
Dosage
The complex of vitamins B1, B6, B12 is available in two forms: tablets and solution for injection.
Neuromultivit tablets are prescribed to adults in a daily dose of 1 tablet 1–3 times a day. The frequency of administration depends on the clinical picture of the disease and individual tolerance. It is recommended to take the tablets preferably after meals, without chewing, with a sufficient amount of water. The course of treatment also depends on the disease, usually the duration ranges from 5 to 30 days.
The injection solution is intended for intramuscular administration; it is strongly not recommended to administer the solution intravenously. The drug at a dosage of 2 ml per day is administered for 5–10 days, then the dosage is reduced and injections are given for three weeks. All procedures are carried out under the supervision of the attending physician.
Experts recommend switching from injections to tablets as soon as possible.
Overdose
It is not recommended to take large doses of Neuromultivit for more than 4 weeks, since constant use of the drug provokes an overdose of one of the vitamins in the composition.
A large dose of vitamin B1 leads to:
- curare-like effect;
- suppression of nerve impulses.
A high concentration of vitamin B6 in the body leads to the following pathologies:
- cerebral convulsions;
- sensitivity disorders;
- hypochromic anemia;
- seborrheic dermatitis;
- neuropathy.
An overdose of vitamin B12 may cause a severe allergic reaction. When using the component for more than a month in large doses, the following symptoms are possible:
- pain in the heart area;
- dysfunction of liver enzymes;
- hypercoagulability.
For negative symptoms, treatment is symptomatic. It is recommended to stop taking the drug if such symptoms occur. Deviation from the norm requires contacting a therapist.
Signs of thiamine overdose and deficiency
The drug "Neuromultivit" consists of one third thiamine hydrochloride. What kind of substance is this and what are the consequences of its deficiency for a person?
Thiamine is synthesized in the intestines, provided that the microflora is not pathogenic. So, a healthy body should not experience a deficiency of vitamin B1. If a person is constantly stressed, irritated, overtired, or does not eat properly, the microflora of the intestinal mucosa is disrupted, and along with it, the production of thiamine is suspended.
Vitamin B1 deficiency is accompanied by the following manifestations:
- insomnia and sleep phase disturbances;
- chronic fatigue and constant feeling of overwork;
- progression of osteochondrosis (if present), which leads to circulatory disorders;
- migraine, headaches due to cerebral circulatory disorders;
- loss of appetite, weight loss;
- low physical endurance.
Thiamine is a water-soluble vitamin, which means that its metabolites are constantly excreted from the body. To achieve an overdose of this component in the tissues, you have to try. Side effects of Neuromultivit often develop with regular use of the drug, as hypervitaminosis of this substance occurs. Here are the manifestations of this condition:
- feeling of heat, hot flashes;
- sweating and hyperhidrosis;
- weakness, nausea;
- loss of consciousness.
An overdose of thiamine is the least common. In stressful situations, when a person finds himself in unusual conditions, the need for vitamin B1 increases tenfold.
Reviews and recommendations from doctors and patients
The NEUROMULTIVIT vitamin complex, reviews of which are positioned as a drug with good results, is considered a wonderful medicine that does not have serious side effects. The effectiveness of the product sets the complex apart from its analogues.
Neuromultivit tablets, reviews of which can be found in various sources, differ in the following factors:
- availability of the drug;
- effectiveness compared to similar products;
- acceptable price.
Neurologists note that the drug is well tolerated by patients, but requires the correct dosage, since the combined vitamin complex can cause an allergic reaction.
Most patients are satisfied with the results of treatment with Neuromultivit tablets. Patients leave positive reviews on the Internet, reporting improvements in their health. Additional benefits of therapy: improved quality of hair and nails.
Reviews
The practice of specialists shows that the use of the drug “Neuromultivit” is advisable in complex therapy - the effect is stronger and longer lasting. Most reviews from patients are positive; there is a rapid elimination of symptoms and consequences of mental, emotional, and physical overload. There are reviews about the help of the medication in the fight against alopecia, problems with nails and asthenia. In the practice of athletes, the medicine allows them to quickly cope with overloads and restore strength.
The few negative reviews are quite explainable by non-compliance with the doses of the medication recommended by the specialist or the timing of its administration.