What does Baralgetas help with? Instructions for use

Price for Baralgetas in pharmacies

The approximate price for Baralgetas is: 100 tablets - 150 rubles, 5 ampoules - 250 rubles.
Education: Rostov State Medical University, specialty “General Medicine”.

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Description and instructions for the drug Baralgetas

Instructions for use Ulkavis
Baralgetas is an antispasmodic analgesic. In other words, this drug is able to relieve spasms by relaxing smooth muscles, and relieve pain associated with these spasms. Metamizole sodium (the active substance of Analgin) is responsible for relieving pain in Baralgetas. It not only relieves pain, but also has an antipyretic and anti-inflammatory effect. Also, fenpiverinium and pitofenone are present here - antispasmodics. The composition of this medicine is similar to such drugs as Revalgin, Spazmalgon.

Baralgetas is used for:

• Spasmodic pain, for example, with colic - renal or liver;
• Painful periods;

- can be used when -

• Non-spastic pain - joint, muscle, after procedures and surgical manipulations (temporary emergency remedy until a more suitable drug is prescribed);
• The need to bring down the temperature (if there are no other means to start treatment).

They produce both tablets and Baralgetas solution, which is administered intramuscularly and intravenously. The instructions for the drug provide information on the use of tablets and solution. Baralgetas dosages are calculated by weight if we are talking about a patient who is under fifteen years of age. Older patients can use two tablets four times a day as a maximum or inject five milliliters twice a day. If you are taking this antispasmodic, you should refrain from alcohol and the use of ethyl alcohol-based medications. Baralgetas can affect the speed of reactions.

Baralgetas is contraindicated for:

• Intolerance to its components;
• Disorders of the liver, heart (tachyarrhythmia);
• Compression of the urethra by the hypertrophied prostate;
• Mechanical intestinal obstruction;
• Glaucoma;
• Pregnancy and lactation.

Side effects and overdose of Baralgetos

Treatment with this drug may cause urinary retention, weakened peristalsis, and decreased blood pressure. Sometimes the condition of the peripheral blood is disrupted, and allergic reactions occur.

If you take a larger dose of Baralgetas than recommended, this will lead to dry mouth, blurred vision, and decreased sweat and urine output.

Analogs

This drug has a large number of similar products. Among the direct analogues are: Plenalgin, Geomag, Spazmalin, Spazgan, Bral, Maxigan, Spazmoblok, Trinalgin, Spazmograd, Renalgan, Revalgin, Bralangin, Spazmalgon.

Among the drugs that have the same effect on the body are: Andipal, Akofil, Quatrox, Benalgin, Tempalgin, Sedal-M, Tetralgin, Pentabufen, Beralgin M, Analgin, Antipirin, Santoperalgin, Quintalgin, Tempanginol.

Interaction

Kaleflon

Baralgetas injection solution is pharmaceutically incompatible with other medications.

The M-anticholinergic effect is enhanced when combined with butyrophenones, H1-blockers (histamine), phenothiazines, Amantadine, tricyclic antidepressants and Quinidine.

Baralgetas increases the effects of ethanol.

Concomitant use with phenothiazine derivatives (Chlorpromazine) can cause the development of severe hyperthermia.

Barbiturates, Phenylbutazone and other liver enzyme inducers reduce the effectiveness of Baralgetas, and anxiolytic and sedative drugs enhance it.

When taking Baralgetas, drugs such as Penicillin, colloidal blood substitutes and radiocontrast agents are contraindicated.

The blood concentration of Cyclosporine while taking Baralgetas may be reduced, as well as the effectiveness of oral hypoglycemic drugs, glucocorticoids, indirect anticoagulants and Indomethacin.

The combined use of cytostatics and Thiamazole increases the possibility of leukopenia.

The effects of Baralgetas are enhanced by taking Codeine, Propranolol and H2-histamine receptor blockers.

Drug interactions

According to the instructions, the use of the drug in the form of injections is incompatible with taking other medications.

If you plan to take the medication together with other medications, you should first consult your doctor.

If you plan to take the medication together with other medications, you should first consult your doctor.

With other drugs

When using the drug together with the following substances, manifestations are possible:

• enhancing the effect of Baralgetas when taking tricyclic antidepressants, butyrophenones, phenothiazines, histamine H1 receptor blockers or Anmantadine;
• enhancing the effect of ethanol-containing drugs;
• hyperemia when taking phenothiazine derivatives;
• deterioration of the properties of Baralgetas when taking barbiturates, phenylbutazone or hepatoinducers;
• enhanced pain relief when taking other similar medications;
• manifestation of leukopenia while taking cytostatic drugs and Thiamazole.

Alcohol compatibility

When using the medicine, you should not drink alcohol at the same time. The medication enhances its effect.

When using the medicine, you should not drink alcohol at the same time.

Instructions for use of Baralgetas (Method and dosage)

Slabilen - instructions for use

The instructions for Baralgetas involve taking the drug orally (in the form of tablets) and parenterally (in the form of an injection solution).

The maximum dose per day for patients over 15 years of age is 6 tablets; it is recommended to take 1-2 tablets of Baralgetas 2-3 times a day. Instructions for use advise swallowing the tablets whole (preferably after a meal) and drinking water. Increasing the daily dose is possible only on the recommendation of a doctor.

For children, Baralgetas can only be prescribed by a doctor and preferably in the minimum daily recommended doses, which should not exceed 2 tablets at the age of 5-7 years; 4 tablets for ages 8-11 years and 6 tablets for ages 12-14 years.

For parenteral (i.v., i.m.) administration of the drug, it is recommended for patients over 15 years of age, in cases of severe and acute colic, to administer 2 ml of Baralgetas intravenously. The injection is carried out slowly, 1 ml over 60 seconds (the injection can be repeated after 6-8 hours). IM injections are given in a dose of 2-5 ml at intervals of 2-3 times in 24 hours. It is not recommended to administer more than 10 ml per day. The duration of therapy is no more than 5 days.

The calculation of the pediatric injection dose takes into account the patient’s age and weight:

• at the age of 3 to 11 months (5-8 kg), only intramuscular administration in a dose of 0.1-0.2 ml is possible;
• at the age of 1 to 2 years (9-15 kg), intravenous administration of 0.1-0.2 ml and intramuscular injection of 0.2-0.3 ml are allowed;
• at the age of 3 to 4 years (16-23 kg), 0.2-0.3 ml can be administered intravenously and 0.3-0.4 ml intramuscularly;
• at the age of 5 to 7 years (24-30 kg), intravenous administration of 0.3-0.4 ml and intramuscular injections of 0.4-0.5 ml are recommended;
• at the age of 8 to 12 years (31-45 kg), an intravenous dose of 0.5-0.6 ml and an intramuscular dose of 0.6-0.7 ml are indicated;
• at the age of 12 to 15 years, the intravenous and intramuscular dose can range from 0.8 to 1 ml.

It is recommended to warm the injection solution, especially before intravenous administration, in your hand.

BARALGETAS

– pitofenone hydrochloride (pitofenone) – fenpiverinium bromide
– metamizole sodium monohydrate (metamizole sodium)

Composition and release form of the drug

10 pieces. – blisters (1) – cardboard packs. 10 pieces. – blisters (10) – cardboard packs.

pharmachologic effect

Combined analgesic and antispasmodic agent. The combination of the components of the drug leads to a mutual enhancement of their pharmacological action.

Metamizole sodium

– a pyrazolone derivative, has an analgesic, antipyretic and weak anti-inflammatory effect, the mechanism of which is associated with inhibition of prostaglandin synthesis.

Pitophenone hydrochloride

has a direct myotropic effect on the smooth muscles of internal organs and causes its relaxation (papaverine-like effect).

Phenpiverinium bromide

has an m-anticholinergic effect and has an additional myotropic effect on smooth muscles.

Pharmacokinetics

Metamizole sodium

After oral administration, metamizole sodium is rapidly absorbed from the gastrointestinal tract. In the intestinal wall it is hydrolyzed to form an active metabolite.

Unchanged metamizole sodium is not detectable in the blood (only after intravenous administration it is found in the blood plasma in a small concentration and quickly becomes inaccessible for determination).

After intramuscular administration, the active substances of the drug are quickly and largely absorbed from the injection site.

Binding to blood plasma proteins is 50-60%. When taken in therapeutic doses, it is excreted in breast milk.

Metamizole sodium undergoes intensive biotransformation in the liver. The main metabolites are 4-methylaminoantipyrine, 4-formylaminoantipyrine, 4-aminoantipyrine and 4-acetylaminoantipyrine. About 20 additional metabolites have been identified, including glucuronic acid derivatives. The main four metabolites are found in the cerebrospinal fluid. It is excreted mainly by the kidneys.

Pitophenone

Rapidly absorbed from the gastrointestinal tract when taken orally. Cmax in blood plasma is achieved after 30-60 minutes. It is quickly distributed in organs and tissues and does not penetrate the BBB.

Metabolized in the liver by oxidative reactions. Excreted in urine. T1/2 is 1.8 hours.

Phenpiverinium bromide

When taken orally, it is quickly absorbed from the gastrointestinal tract. Cmax in blood plasma is achieved within 1 hour. Does not penetrate the BBB. Excreted unchanged in urine 32.4-40.4%, in bile – 2.3-5.3%.

Indications

Pain syndrome (mild or moderate) with spasms of smooth muscles of internal organs: renal colic, spasm of the ureter and bladder; biliary colic; biliary dyskinesia; postcholecystectomy syndrome; intestinal colic; chronic colitis; algodismenorrhea; diseases of the pelvic organs. For short-term treatment of arthralgia; myalgia; neuralgia, sciatica.

As an auxiliary drug for pain after surgical interventions and diagnostic procedures.

Contraindications

Severe liver and/or renal failure; inhibition of bone marrow hematopoiesis; deficiency of glucose-6-phosphate dehydrogenase; tachyarrhythmia; severe angina; decompensated chronic heart failure; collapse; angle-closure glaucoma; prostatic hyperplasia (with clinical manifestations); intestinal obstruction; megacolon; pregnancy (especially the first trimester and the last 6 weeks); lactation period; children under 3 months of age or body weight less than 5 kg (for intravenous administration); children under 5 years of age (for tablets); hypersensitivity (including to pyrazolone derivatives).

Carefully :

renal/liver failure; bronchial asthma; tendency to arterial hypotension; hypersensitivity to NSAIDs; urticaria or acute rhinitis caused by taking acetylsalicylic acid or other NSAIDs.

Dosage

Inside

Adults and adolescents over 15 years old: 1-2 tablets. 2-3 times a day, without chewing, with a small amount of liquid. Children aged 12-14 years: single dose – 1 tablet, maximum daily dose – 6 tablets. (1.5 tab.

4 times/day), children aged 8-11 years – 0.5 tablets, maximum daily dose – 4 tablets. (1 tablet 4 times/day), children aged 5-7 years – 0.5 tablet, maximum daily dose – 2 tablets. (0.5 tablet 4 times/day).

Parenteral (i.v., i.m.)

For adults and adolescents over 15 years of age with acute severe colic, 2 ml are administered intravenously slowly (1 ml over 1 minute); if necessary, re-inject after 6-8 hours. IM - 2-5 ml of solution 2-3 times a day. The maximum daily dose should not exceed 10 ml (corresponding to 5 g of metamizole sodium).

The duration of the course of treatment is determined depending on the clinical symptoms and etiopathogenesis of the disease, but should not exceed 5 days. Calculation of the dose for children with IV and IM administration: 3-11 months (5-8 kg) – only IM – 0.1-0.2 ml; 1-2 years (9-15 kg) – IV – 0.1-0.

2 ml, IM – 0.2-0.3 ml; 3-4 years (16-23 kg) – IV – 0.2-0.3, IM – 0.3-0.4 ml; 5-7 years (24-30 kg) – IV – 0.3-0.4 ml, IM – 0.4-0.5 ml; 8-12 years (31-45 kg) – IV – 0.5-0.6 ml, IM – 0.6-0.7 ml; 12-15 years – IV and IM – 0.8-1 ml.

Before administering the injection solution, it should be warmed in your hand.

Allergic reactions:

urticaria (including on the conjunctiva and mucous membranes of the nasopharynx), angioedema, in rare cases - malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), bronchospasm, anaphylactic shock.

From the hematopoietic system:

thrombocytopenia, leukopenia, agranulocytosis (may be manifested by the following symptoms: unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of vaginitis or proctitis).

From the cardiovascular system:

decrease in blood pressure.

From the urinary system:

impaired renal function, oliguria, anuria, proteinuria, interstitial nephritis, red staining of urine.

Anticholinergic effects:

dry mouth, decreased sweating, accommodation paresis, tachycardia, difficulty urinating.

Local reactions:

with intramuscular administration, infiltrates are possible at the injection site.

Drug interactions

Histamine H1 receptor blockers, butyrophenones, phenothiazines, tricyclic antidepressants, amantadine and quinidine

– it is possible to enhance the m-anticholinergic effect.

Chlorpromazine or other phenothiazine derivatives

– development of severe hyperthermia is possible.

Non-narcotic analgesics, tricyclic antidepressants, oral hormonal contraceptives and allopurinol

– increase the toxicity of the drug.

Phenylbutazone, barbiturates and other microsomal enzyme inducers

– decrease in the effectiveness of metamizole sodium.

Sedatives and anxiolytics (tranquilizers)

– enhancing the analgesic effect of metamizole sodium.

Radiocontrast drugs, colloidal blood substitutes and penicillin

– combinations with drugs containing metamizole sodium should not be used.

Cyclosporine

– a decrease in the concentration of cyclosporine in the blood is possible.

Oral hypoglycemic agents, indirect anticoagulants, corticosteroids and indomethacin

– metamizole sodium displaces these drugs from their connection with proteins, as a result of which the severity of their action may increase.

Thiamazole and cytostatics

– increased risk of developing leukopenia.

Medicines with myelotoxic effects:

enhancing the hematotoxic effect of the drug.

Codeine, histamine H2 receptor blockers, propranolol

– enhanced effect of the drug due to slower inactivation of metamizole sodium.

Ethanol

– enhanced effects of ethanol.

The solution for injection is pharmaceutically incompatible with other drugs.

special instructions

With long-term (more than a week) treatment, monitoring of the peripheral blood picture and the functional state of the liver is necessary.

If agranulocytosis is suspected or thrombocytopenia is present, the drug should be discontinued.

The use of the drug to relieve acute abdominal pain is unacceptable until the cause of the disease is determined.

Intolerance is very rare, but the risk of developing anaphylactic shock after intravenous administration of the drug is relatively higher than after taking the drug orally.

In patients with atopic bronchial asthma and hay fever, the risk of developing allergic reactions increases.

Parenteral administration of the drug should be used only in cases where oral administration is impossible or absorption from the gastrointestinal tract is impaired.

The IV injection should be carried out slowly, with the patient lying down and under the control of blood pressure, heart rate and respiratory rate.

Particular care must be taken when administering more than 2 ml of solution (there is a risk of a sharp decrease in blood pressure).

For intramuscular administration it is necessary to use a long needle.

When treating children under 5 years of age and patients receiving cytostatics, the use of metamizole sodium should only be carried out under medical supervision.

It is possible that the urine may turn red due to the release of a metabolite (it has no clinical significance).

During treatment with the drug, it is not recommended to take ethanol.

Impact on the ability to drive vehicles and operate machinery

During treatment, drivers of vehicles and persons engaged in potentially hazardous activities that require rapid psychomotor reactions should be careful.

Pregnancy and lactation

The use of the drug is contraindicated during pregnancy (especially in the first trimester and in the last 6 weeks).

If it is necessary to use the drug during lactation, breastfeeding should be discontinued.

Use in childhood

IV administration of the drug is contraindicated in children under 3 months of age or with a body weight of less than 5 kg.

The use of the drug in tablet form is contraindicated in children under 5 years of age.

For impaired renal function

The use of the drug is contraindicated in cases of severe renal failure.

The drug should be prescribed with caution in case of renal failure.

For liver dysfunction

The use of the drug is contraindicated in cases of severe liver failure.

The drug should be prescribed with caution in case of liver failure.

The description of the drug BARALGETAS is based on the officially approved instructions for use and approved by the manufacturer.

The information provided on drug prices does not constitute an offer to sell or purchase goods. The information is intended solely for comparing prices in stationary pharmacies operating in accordance with Article 55 of the Federal Law “On the Circulation of Medicines”.

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Source: https://health.mail.ru/drug/baralgetas/

What are Baralgetas tablets taken for?

1. This medicine helps with mild to moderate pain of various origins.
2. Baralgetas is prescribed for spasms of the smooth muscles of internal organs that occur with hepatic, intestinal and biliary colic, biliary dyskinesia, chronic colitis, etc.
3. This medication is effective for algodismenorrhea and other diseases of the pelvic organs.
4. Baralgetas is often used for short-term treatment of sciatica, neuralgia, arthralgia and myalgia.
5. As an adjuvant treatment, this remedy is used after various diagnostic or surgical procedures.
6. In some cases, doctors recommend this drug to normalize elevated body temperature during infectious-inflammatory or colds.

Directions for use and dosage

Methods of taking this drug depend on the patient’s age, the nature of his illness, as well as the individual characteristics of his body.

• Adults and adolescents over 15 years of age are recommended to take one or two tablets orally several times a day. The maximum daily dosage of the drug is six tablets. The duration of such treatment should not exceed five days. Increasing the duration of treatment or dosage of the drug is possible only under medical supervision.
• Only a pediatrician can prescribe Baralgetas for children if the risk of taking it is significantly less than the positive effect it has. The recommended dosage for children aged 6 to 8 years is half a tablet several times a day. Children from 9 to 12 years old should take three-quarters of a tablet 2 to 3 times a day. Those children whose age ranges from 13 to 15 years old should take the whole tablet several times a day.

Interaction with other medications

Taking this medication with other substances or medications may cause a number of side effects, so it is important to read the following information before taking it:

• alcohol and Baralgetas are incompatible;
• simultaneous use of this medication with other non-narcotic analgesics may cause a mutual enhancement of their toxic properties;
• Baralgetas, when taken with tricyclic antidepressants or contraceptives, disrupts the metabolism of metamizole in the liver, increasing its toxicity;
• tranquilizers and sedatives significantly enhance the analgesic effect of Baralgetas.

Baralgetas is a combination drug that has analgesic, anti-inflammatory and antispasmodic effects. If a doctor recommended it to you, but you do not know what Baralgetas is taken for and in what situations it is effective, carefully read this instructional article.

In it you will find a lot of interesting information on the use, combination of this drug with other medications, etc.

pharmacological action drug substance

Reviews from doctors

Doctors recommend this drug to relieve pain and spasms.

Maria, general practitioner, 41 years old, Moscow

This drug is an antispasmodic and analgesic medicine created on the basis of three active components. They are selected so as to mutually enhance each other's effects. The therapeutic effect of the drug is to alleviate antispasmodic effects, relieve pain and relieve inflammation. The medication is indispensable for diseases accompanied by fever and pain of mild to moderate severity.

Self-administration of this medicine to get rid of severe abdominal pain is unacceptable until the causes of the ailment are clarified. According to the instructions for use, contraindications also include age under 5 years, severe renal failure, and pregnancy. This analgesic and antispasmodic has proven itself to be an effective analgesic and antipyretic in the treatment of colds in adults and school-age children.

Leonid, doctor, 48 years old, Surgut

It just so happened that while working as part of an ambulance resuscitation team, I became infected with hepatitis C. This diagnosis was made 5 years ago during a routine examination. Now I have to follow a strict diet and undergo courses of expensive antiviral treatment.

Diet violations and stress provoke an attack of hepatic colic. It begins with sharp pain in the right hypochondrium, radiating to the back, nausea and a slight increase in temperature. In such cases, I inject No-shpu or another antispasmodic and painkiller intramuscularly, since taking the tablets provokes vomiting.

Indications and contraindications for the use of Baralgetas

The main task of Baralgetas is to eliminate pain of various localizations. That is why it is prescribed for spastic pain, for example, for renal or hepatic colic, as well as for painful premenstrual syndrome.

In addition, treatment takes place for pain of a non-spastic nature, for example, joint and muscle pain, as well as after procedures and surgical manipulations. Baralgetas is also taken when there is an urgent need to reduce the temperature and eliminate signs of fever.

Among the contraindications to the use of this antispasmodic, pathologies of the heart, liver and kidneys should be highlighted; mechanical intestinal obstruction; glaucoma and hypertrophied prostate.

It is necessary to limit the use of Baralgetas during pregnancy and lactation, but do not forget about the individual intolerance of the active components of the medicine by the sick body.

special instructions

Impact on the ability to drive vehicles and operate machinery

Baralgetas may reduce the speed of psychomotor reactions. During therapy, it is recommended to exclude potentially hazardous activities that require maintaining concentration. You must also stop driving a car.

Pregnancy and lactation

The manufacturer lists pregnancy as a contraindication for the use of Baralgetas. It is strictly forbidden to take the drug in the first six weeks of gestation. The medication is not compatible with the lactation period. Breastfeeding should be stopped during therapy.

Use in childhood

Baralgetas is used in pediatrics, but has age restrictions. In the form of a solution, the drug is prohibited for children under three months and weighing less than five kilograms. The tablets can only be taken from the age of five.

For kidney problems

The instructions warn against self-administration of Baralgetas in case of kidney dysfunction. In the presence of such pathologies, the drug is used with caution. Severe renal failure is considered an absolute contraindication for the use of an analgesic.

For liver disorders

Severe liver failure is a contraindication for the use of Baralgetas. For other liver dysfunctions, the drug is recommended to be used with caution.

Conditions for dispensing from pharmacies

Baralgetas is sold in pharmacies by prescription.

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Pharmacological properties

Pharmacodynamics

Baralgetas is a combined analgesic and antispasmodic drug, the components of which mutually enhance the pharmacological effects of each other.

Metamizole sodium, which is a pyrazolone derivative, provides antipyretic, analgesic and weak anti-inflammatory effects due to inhibition of prostaglandin synthesis.

Phenpiverinium bromide has an m-anticholinergic effect, and also additionally has a myotropic effect on smooth muscles.

Pitophenone hydrochloride provides a direct myotropic effect on smooth muscles, causing them to relax (papaverine-like effect).

Metamizole sodium

Metamizole sodium after oral administration is rapidly absorbed from the gastrointestinal tract. In the intestinal wall, the substance is hydrolyzed to form an active metabolite. Unchanged metamizole sodium is not detected in the blood (it is found in low concentrations in the blood plasma only after intravenous administration, and quickly becomes inaccessible for determination). As a result of intramuscular administration, a significant proportion of the components of the drug are quickly absorbed from the injection site. Approximately 50–60% of the substance binds to plasma proteins. When taken in therapeutic doses, it is excreted into breast milk.

Intensive biotransformation of metamizole sodium occurs in the liver. Main metabolites: 4-methylaminoantipyrine, 4-aminoantipyrine, 4-acetylaminoantipyrine, 4-formylaminoantipyrine. Approximately 20 additional metabolites have been identified, including glucuronic acid derivatives. Four major metabolites are released into the cerebrospinal fluid. Metamizole sodium is mainly excreted by the kidneys.

Phenpiverinium bromide

Fenpiverinium bromide is rapidly absorbed from the gastrointestinal tract after oral administration. Reaching the maximum concentration in blood plasma occurs after 1 hour. Does not penetrate the blood-brain barrier. From 32.4 to 40.4% is excreted unchanged with urine, and from 2.3 to 5.3% with bile.

Pitophenone

Pitophenone after oral administration is rapidly absorbed from the gastrointestinal tract. Reaching the maximum concentration in the blood plasma occurs after 0.5–1 hour. It is quickly distributed in tissues and organs and does not penetrate the blood-brain barrier. Metabolized in the liver through oxidative reactions. Excreted in urine. The half-life is 1.8 hours.

Composition and release form

Baralgetas comes in two formats:

Indications for use

The indication for use is moderate or mild pain due to spasms of the smooth muscles of internal organs - algodismenorrhea, spasmodic pain along the intestines, hepatic and renal colic.

The drug can also be used for short-term symptomatic therapy for pain in the joints, myalgia, sciatica, and neuralgia. As an adjuvant it can be prescribed to reduce pain after diagnostic and surgical procedures.

If necessary, it can be used to reduce elevated body temperature against the background of infectious, inflammatory and colds.

What does Baralgetas help with?

Instructions for use indicate the indications for use of Baralgetas:

• weak, moderate pain syndrome with spasms: renal colic, spasms of the ureters, bladder;
• biliary, intestinal colic;
• algodismenorrhea;
• biliary dyskinesia;
• chronic colitis;
• postcholecystectomy syndrome;
• arthralgia, neuralgia, myalgia, sciatica;
• pain after operations and diagnostic examinations.

Contraindications

Contraindicated in the following cases:

• inhibition of bone marrow hematopoiesis;
• tachyarrhythmias;
• severe renal and/or liver failure;
• hypersensitivity (including to pyrazolone derivatives);
• severe angina;
• intestinal obstruction;
• decompensated CHF;
• deficiency of glucose-6-phosphate dehydrogenase;
• angle-closure glaucoma;
• collapse;
• megacolon;
• prostatic hyperplasia (with clinical manifestations);
• period of pregnancy (especially the first trimester and the last 6 weeks) and breastfeeding;
• additionally for tablets – children’s age (up to 5 years);
• additionally for intravenous administration - body weight less than 5 kg or infancy (up to 3 months).

Prescribed with extreme caution in case of a tendency to arterial hypotension, liver and kidney failure, the “aspirin” triad, bronchial asthma, hypersensitivity to other non-steroidal anti-inflammatory drugs

Side effects

• Angioedema, shock, necrolysis, erythema, bronchospasm;
• Anuria, change in urine color (this does not affect the tests in any way), nephritis, proteinuria, and oliguria;
• Thrombocytopenia, agranulocytosis and leukopenia;
• A sharp decrease in blood pressure;
• Tachycardia, dry mouth, decreased/increased sweating, accommodation paresis.

In case of overdose, symptoms such as drowsiness, abdominal pain, vomiting, convulsions, a sharp decrease in blood pressure, and disturbances in kidney function are observed. If this condition occurs, the patient’s stomach is washed using any available method, and activated charcoal is also given.

Contraindications

This drug should not be taken for conditions such as:

• Allergy to components included in the product;
• Severe form of renal/liver failure;
• Angina pectoris, glaucoma, intestinal obstruction, hyperplasia, tachyarrhythmia;
• Collapse and also megacolon.

In addition, the contraindication for intravenous administration of the solution is the child’s age (up to 3 months), and for tablets - 5 years.

In addition, the drug should be prescribed carefully if there is an as triad.

Pregnancy

During pregnancy it is better not to use this remedy. This is due to the fact that the medicine can have a negative effect on the fetus.

During breastfeeding, you should also avoid taking the drug. This is due to the fact that the medicine can have a negative effect on the baby. If you can’t stop taking it, then you need to decide on stopping natural feeding.

Additionally

During treatment with Baralgetas, it is not recommended to take ethanol. With long-term (more than a week) treatment, monitoring of the peripheral blood picture and the functional state of the liver is necessary. If agranulocytosis is suspected or thrombocytopenia is present, the drug should be discontinued. It is not permissible to use it to relieve acute abdominal pain (until the cause is determined). Use in nursing mothers requires cessation of breastfeeding. Intolerance is very rare, but the risk of developing anaphylactic shock after intravenous administration of the drug is relatively higher than after taking the drug orally. Patients with atopic bronchial asthma and hay fever have an increased risk of developing allergic reactions. Parenteral administration should be used only in cases where oral administration is not possible (or absorption from the gastrointestinal tract is impaired)

Special caution is required when administering more than 2 ml of solution (risk of a sharp decrease in blood pressure). IV injection should be carried out slowly, in the “lying” position and under the control of blood pressure, heart rate and respiratory rate

When treating children under 5 years of age and patients receiving cytostatic drugs, metamizole sodium should only be taken under medical supervision. For intramuscular administration it is necessary to use a long needle. It is possible that the urine may turn red due to the release of a metabolite (it has no clinical significance). During treatment, drivers of vehicles and persons engaged in potentially hazardous activities that require quick physical and mental reactions should be careful.

Storage method

The drug should be stored at room temperature in a place where children will not have access. The place should also be protected from moisture and light.

If all conditions are met, both dosage forms of the drug can be stored for 5 years. After the expiration date has expired, it is prohibited to continue using the drug.

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Overdose

Symptoms: gastralgia, hypothermia, nausea, vomiting, tachycardia, decreased blood pressure, shortness of breath, drowsiness, tinnitus, disturbances of consciousness, delirium, hemorrhagic syndrome, acute agranulocytosis, oliguria, acute liver and/or renal failure, respiratory muscle paralysis, convulsions .

Treatment: gastric lavage, administration of water-salt solutions, activated carbon, forced diuresis, hemodialysis. In case of development of convulsive syndrome, intravenous administration of fast-acting barbiturates and diazepam is recommended.

Side effects

When using Baralgetas, adverse reactions may develop. The instructions indicate the following:

• allergy, urticaria, erythema, necrolysis;
• bronchospasm;
• leukopenia, agranulocytosis, thrombocytopenia;
• stomatitis, difficulty swallowing, dry mouth;
• vaginitis, proctitis;
• rise in temperature, chills;
• swelling of the nasopharynx;
• accommodation paresis;
• decreased blood pressure, tachycardia;
• oliguria, proteinuria, anuria, interstitial nephritis, difficulty urinating;
• infiltration at the injection site.

Baralgetas: instructions for use (tablets)

Dosage regimens for this drug are different. They primarily depend on the age of the patient, on the individual characteristics of his body, as well as on the form in which you are going to take the medicine Baralgetas:

• Adults and adolescents over 15 years of age are recommended to take 1-2 tablets of this medicine several times a day. The tablets should not be chewed; they should be swallowed whole with plenty of liquid.
• Children from 12 to 14 years old should take 1 tablet several times a day. The maximum daily dose of this drug for children of this age category is 6 tablets. Children aged 8 to 11 years are recommended to take 0.5 tablets several times a day. The maximum daily dose of this medicine is four tablets. Children under seven years of age should be given Baralgetas only as recommended by their doctor.