The use of Proviron in bodybuilding: instructions, doses, analogues

Description of the drug[edit | edit code]

Proviron from SCHERING Provimed from Balkan (Moldova) Proviger from Gerth Pharmaceuticals (50 tablets of 50 mg each)
Proviron

(active ingredient -
mesterolone
) is a hormonal drug that has moderate androgenic activity[1] and significantly enhances erectile function. Proviron is often used in bodybuilding during a cycle of anabolic steroids to solve various problems.

Among the well-known manufacturers of mesterolone are various branches of the company Schering ( Proviron in the form of tablets of 25 mg

), the Moldovan company Balkan Pharmaceuticals (
Provimed, 50 mg tablets
), Gerth Pharmaceuticals (Proviger, 50 mg tablets) and some others.

It is a weak aromatase inhibitor, i.e. it slightly interferes with the conversion of steroids to estrogens in the body.[2][3][4] According to numerous reports from athletes, in practice, Proviron does not prevent gynecomastia, water retention, female pattern fat deposition and other estrogen side effects.

It has virtually no effect on the body’s production of its own testosterone (in large doses it can suppress), but it helps to increase the concentration of free testosterone in the blood by blocking the activity of sex hormone-binding globulin. These properties make Proviron an attractive option during a cycle.

It is often used as part of post-cycle therapy, although its expediency is questionable, since it does not have the ability to restore the secretion of endogenous testosterone.[5]

Legal status[edit | edit code]

Mesterolone, its salts, isomers, esters, all dosage forms and trade names are included in the list of potent substances on the basis of Decree of the Government of the Russian Federation of December 29, 2007 N 964. Criminal liability entails: illegal production, processing, acquisition, storage, transportation or forwarding for the purpose of sales, as well as illegal sale, or equipment for its production or processing.

Large size

Mesterolone is 2.5 g or more.[6]

How to take Proviron during the course[edit | edit code]

The usual daily dosage for men is 50 mg per day, divided into two equal doses, preferably after meals. A dosage of up to 100 mg of Proviron per day is considered acceptable. Higher doses of Proviron may result in effects opposite to those expected. For prolonged erections, which are often quite painful and uncomfortable, the dosage of the drug should be reduced or discontinued altogether.

Considering that the drug increases libido and improves potency in men, its use is justified during a course of drugs that lower libido (for example, Deca-Dic when using nandrolone or Tren-Dic from trenbolone).

In addition, Proviron in bodybuilding is often used in pre-competition preparation to increase muscle hardness and give it definition. It is a favorite drug of Western film actors to give a muscular appearance to those who are afraid to use heavier steroid “artillery”. It is also used by female bodybuilders to add density to the muscles, but their dosages should not exceed 25 mg per day for no more than four weeks to avoid the phenomenon of masculinization. Although professional female bodybuilders do not adhere to these standards.

Medical use[edit | edit code]

“Improves the quality and increases the number of sperm. It compensates for the lack of production of male sex hormones (androgens), having a stimulating effect on the development of male genital organs and secondary sexual characteristics, improves libido and potency, exhibits anabolic properties, and stimulates erythropoiesis.” Mode of application:

Orally, without chewing, 25 mg 1–3 times a day.[7]

According to some studies, Proviron has performed well as an antidepressant. For the experiment, we took masterolone and amitriptyline. Both drugs showed good results in improving mood. However, Masterolon turned out to be less toxic to the human body, with fewer side effects. [8]

Contraindications and warnings

Proviron is strictly contraindicated in case of prostate cancer and the presence of other oncological diseases.
Use for the purpose of improving physical performance without a preliminary medical examination is highly undesirable.
Androgens can aggravate clinically manifested prostate carcinoma, malignant tumors of the prostate gland.
In rare cases, the occurrence of malignant and benign liver tumors has been recorded. There are isolated cases of internal bleeding that are life-threatening.
Prolonged uncontrolled erection is possible. In this case, the dose should be reduced. In especially severe cases, treatment is stopped completely.

Side effects[edit | edit code]

It is not toxic to the liver in moderate dosages, which makes it safe to take during a course of several weeks. Does not suppress the hypothalamic-pituitary-testicular axis.[9] Given the chemical nature and similarity to dihydrotestosterone, side effects such as prostate hypertrophy and male pattern baldness are possible.

For the purpose of prevention, periodic examinations of the prostate gland are recommended. Caution for use After taking the hormonal substances that make up the drug Proviron, the formation of benign, and even more rarely, malignant liver tumors was very rarely observed. In some cases, intra-abdominal bleeding caused by such tumors was life-threatening. If a man using Proviron has severe pain in the upper abdomen, an enlarged liver, or signs of intra-abdominal bleeding, the possibility of a liver tumor should be considered in the differential diagnosis

Weakening the effect of AC[edit | edit code]

Many authors, for example, A. Vasilenko and others, point to the use of proviron and anabolic steroids (AS) of the same receptors, which supposedly reduces the effect of the latter. This information first appeared in Dan Duchaine's Underground Steroid Handbook II. However, basic knowledge of pharmacokinetics allows us to refute this. Firstly, this anti-estrogen is quickly destroyed in the muscles to inactive metabolites. Secondly, due to its high affinity for binding proteins (SHBG), the drug can increase the concentration of free AS, which increases the effectiveness of the course.

Legal status[edit | edit code]

Proviron is freely available in Ukraine.

There are several types of use of Proviron:

1) use in combination with testosterone (any aromatase composition is suitable). As a result, there is no scattering of female estrogen hormones, as well as no conversion. This is why Proviron protects against estrogenic side effects that so often affect athletes. A number of studies have shown results indicating that Proviron helps prevent water retention in the body. It is believed that Proviron reduces estrogen sensitivity.

2) Proviron helps expand the functions of testosterone. Including, it increases its potential.

3) Proviron used before competitions increases muscle volume.

4) Taken in combination with Trenbolone gives a good effect. Proviron is prescribed to men who suffer from chronic impotence, as well as depressed hormonal levels (low levels of the male hormone testosterone).

Choice of antiestrogens[edit | edit code]

Very often the question is raised which anti-estrogenic drug should be preferred.

Tamoxifen

is a drug that blocks estrogen receptors, but does not prevent the formation of estrogen. Tamoxifen is more conducive to restoring your own testosterone, as it can directly influence the pituitary gland. The disadvantage is that it slightly reduces the anabolic activity of steroid drugs. Only used during PCT.

Proviron

increases the concentration of androgens due to binding to SHBG, thus increasing the effectiveness of the course. However, Proviron has not been shown in studies to restore testosterone secretion, unlike tamoxifen.[11][12] Repeated analyzes of hormone levels[13] have shown that the antiestrogenic effect of Proviron is practically not manifested during the course.

Taking into account the advantages and disadvantages of both drugs, the optimal course of steroids is structured as follows (relevant only for aromatizable AS):

Starting from the 2nd week of the course, Proviron is administered at a dose of 50 mg per day. Additionally, aromatase inhibitors should be used to control estrogen levels.
Immediately after the end of the course, Proviron is stopped and after the steroids are removed from the body, tamoxifen is prescribed for 2-3 weeks at a dose of 10-20 mg per day.

How to combine Proviron correctly?

Proviron is not only a drug for PCT, but also combines well with some steroids. Since it increases libido, it can be used in conjunction with erectile dysfunction drugs. These are deka-dik, tren-dik and others. Proviron is effective in cases where an athlete sets a goal to increase muscle hardness and relief. Interesting fact: almost all Hollywood actors use it to create a muscular look. Proviron is also a favorite among women who devote themselves to bodybuilding. A woman is advised to take no more than 26 mg per day. However, professional athletes can determine the dosage depending on individual characteristics.

Notes[edit | edit code]

Andrologia. 1983 May-Jun;15(3):283-6. German.
Source: William Llewellyn's, Anabolics 9th edition, 2009
https://experimentjournal.com/expadmin/pdf_files/exp_11.4_721-725.pdf
https://thinksteroids.com/articles/antiestrogens-anti-aromatases-estrogen-antagonists/
Kövary PM, Lenau H, Niermann H, Zierden E, Wagner H (May 1977). "Testosterone levels and gonadotrophins in Klinefelter's patients treated with injections of mesterolone cipionate." Arch Dermatol Res 258(3):289–94.
https://base.garant.ru/12158202/#block_3000
Register of Medicines of Russia - https://www.rlsnet.ru/tn_index_id_2669.htm
https://www.buildbody.org.ua/farmakologiya/proviron-mesterolon-otzyvy-kurs-pkt-pobochnye-effekty
Spitz IM, Margalioth EJ, Effect of non aromatizable androgens on LHRH and TRH responses in primary testicular failure. PMID: 2892728
Decree of the Government of the Russian Federation of December 29, 2007 N 964 “On approval of lists of potent and toxic substances for the purposes of Article 234 and other articles of the Criminal Code of the Russian Federation, as well as large amounts of potent substances for the purposes of Article 234 of the Criminal Code of the Russian Federation”
Effect of non aromatizable androgens on LHRH and TRH responses in primary testicular failure. Horm Metab Res. 1984 Sep;16(9):492-7.
The effect of mesterolone on sperm count, on serum follicle stimulating hormone, luteinizing hormone, plasma testosterone and outcome in idiopathic oligospermic men.Int J Gynaecol Obstet. 1988 Feb;26(1):121-8.
https://do4a.com/threads/Analysis-of-hormone-tests-advice-from-a-specialist.5626

Release form, composition, price

Dispensed strictly according to prescription. The price ranges from 700 to 1500 rubles. The cost of its analogue, Mesterolone, is much higher: from 2,500 rubles. Packaging: blisters of 50 tablets. The active substance is mesterolone. Fillers:

lactose monohydrate,
antifungal preservatives,
polyvidone,
corn starch,
Magnesium stearate.

Urologist Oleg Nikolaenko

In my practice, I prescribe Proviron for the treatment of infertility. The drug not only has a “replacement” effect in case of low testosterone production, but also stimulates sperm motility.

In most cases, asthenozoospermia is the main cause:

1.	development of reproductive disorders
2.	impossibility of conception

Stimulation of libido is more likely an additional, rather than the main effect of Proviron.

In case of complex disorders of the reproductive system, taking such a drug can solve several problems at once:

increase potency;
regulate hormonal levels;
improve the state of reproductive function.

Casanova set from 899 rub.

Lovelace set from 899 rub.

Family set from 1199 rub.

How to choose a drug to increase potency

Available analogues

The modern pharmacological market is distinguished by a wide variety of drugs that can replace Proviron. Opinions about their effectiveness differ radically. It all depends on the individual characteristics of each person’s body, as well as different training programs and diet. Any drugs that help stimulate the production of natural testosterone are analogues of the sought-after Proviron. The following products are in greatest demand:

"Clomiphene."
"Tamoxifen."
"Prostopin."
"Testagen".
HCG.

Many men use Proviron Forte to improve erectile function and increase libido levels. This product contains exclusively plant extracts.

Similar drugs:

Omnadren 250 (Omnadren 250) Solution for injection
Andriol Capsule
Sustanon-250 (Sustanon 250) Solution for intramuscular administration
Androgel (Androgel) Gel for external use
Nemestran Capsule
Methyltestosterone Oral tablets
Nebido Solution for intramuscular administration
Sustanon-250 (Sustanon 250) Solution for injection
Andriol TK Capsule

** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use Proviron, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

Are you interested in the drug Proviron? Do you want to know more detailed information or do you need a doctor's examination? Or do you need an inspection? You can make an appointment with a doctor - the Euro lab is always at your service! The best doctors will examine you, advise you, provide the necessary assistance and make a diagnosis. You can also call a doctor at home . Euro lab clinic is open for you around the clock.

** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Proviron is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

If you are interested in any other drugs and medications, their descriptions and instructions for use, information about the composition and form of release, indications for use and side effects, methods of use, prices and reviews of drugs, or you have any other questions and suggestions - write to us, we will definitely try to help you.