Tavegil - instructions for use, analogues, price, side effects

Tavegil belongs to the pharmacological group of antihistamines. The main active ingredient is clemastine.

The drug has antihistamine and antiallergic effects. It also has an antipruritic effect. The therapeutic effect is achieved due to the ability of certain components of the drug to block the so-called H1 histamine receptors and reduce capillary permeability.

Tavegil is used in the case of hay fever, urticaria, allergic rhinitis, eczema, dermatosis, dermatitis. Injection of the drug will eliminate allergic or anaphylactic shock.

Release form and composition

Dosage forms of Tavegil:

Tablets: flat, round, with a beveled edge, white or almost white, with “OT” engraved on one side and a score line on the other (5 pcs. in blisters, in a cardboard pack of 2, 3 or 6 blisters; 10 pcs. in blisters, in a cardboard box 1, 2, 3 or 6 blisters);
Solution for intravenous and intramuscular administration: colorless or from light yellow to pale greenish-yellow, transparent (2 ml in ampoules, 5 ampoules in plastic trays, 1 tray in a cardboard box);
Syrup for oral administration (60 ml in dark glass bottles, 1 bottle in a cardboard box complete with a dispenser cap).

Composition of tablets (1 pc.):

Active ingredient: clemastine (in the form of hydrofumarate) – 1 mg;
Auxiliary components: corn starch, lactose monohydrate, magnesium stearate, povidone and talc.

Composition of the solution (in 1 ml):

Active ingredient: clemastine (in the form of hydrofumarate) – 1 mg;
Auxiliary components: ethanol, sorbitol, sodium citrate dihydrate, propylene glycol, water for injection.

Syrup composition (5 ml):

Active ingredient: clemastine (in the form of hydrofumarate) – 0.5 mg;
Auxiliary components: methyl p-hydroxybenzoate, propyl p-hydroxybenzoate, disodium hydrogen phosphate, sorbitol 70%, potassium dihydrogen phosphate, sodium saccharin, propylene glycol, demineralized water, mixture of fruit flavoring additives (ABRAC S-2718).

Tavegil price

The cost depends on the form of release of Tavegil and the configuration. The average price of 1 mg tablets No. 10 is 150–250 rubles.

Names of Moscow pharmacies	Price, rubles
ASNA	150
Pharmacy chain "36.6"	150
NIKA	150
Online pharmacy "Dialogue"	165
ElixirPharm	210

Dosage and method of administration

As indicated in the instructions for use, Tavegil tablets should be taken before meals with water.

Children aged 6-12 years are prescribed 1/2-1 tablet. before breakfast and at night.
Orally, adults and children over 12 years of age are prescribed 1 tablet. (1 mg) morning and evening. In cases that are difficult to treat, the daily dose can be up to 6 tablets. (6 mg).

Tavegil syrup is taken orally before breakfast and before bedtime, using the supplied measuring cup.

Adolescents over 12 years of age and adults are prescribed 10 ml 2 times a day; in severe forms of the disease, the daily dose can be increased to 60 ml to achieve a clinical effect.

Recommended doses of Tavegil for children depending on age:

6–12 years: 5–10 ml 2 times a day;
3–6 years: 5 ml 2 times a day;
1–3 years: 2–2.5 ml 2 times a day.

During pregnancy

According to the instructions for use, when carrying a fetus, it is prohibited to use Tavegil in any form of release . This is explained by the results of clinical studies, which confirmed that the components of the antihistamine penetrate the placental barrier and are excreted in breast milk. An absolute contraindication is the period of lactation. If treatment with Tavegil is necessary, the question of temporarily transferring the child to artificial formula is raised.

Pharmacological properties

Pharmacodynamics

The active component of Tavegil, clemastine, is a blocker of H1-histamine receptors and belongs to ethanolamine derivatives. It is characterized by a strong antihistamine and antipruritic effect. The drug begins to act quickly, the duration of action reaches 12 hours. Clemastine prevents the development of vasodilation and smooth muscle contraction that histamine induces. Tavegil exhibits antiallergic and anticholinergic effects, reduces itching, slows down the formation of edema, inhibits exudation, and reduces the permeability of blood vessels and capillaries.

Pharmacokinetics

After oral administration of Tavegil, clemastine is almost 100% absorbed from the gastrointestinal tract (GIT). Its maximum plasma concentration is recorded 2–4 hours after administration.

The degree of binding to blood plasma proteins reaches 95%. The drug is excreted from the body in a biphasic manner, the corresponding half-lives being 3.6±0.9 and 37±16 hours. Clemastine is actively involved in hepatic metabolism processes. Excretion of metabolites occurs primarily through the kidneys (approximately 45–65%), and the active substance, unchanged, is found in urine only in trace concentrations. In nursing women, clemastine may pass into breast milk in small quantities.

When is Tavegil prescribed?

Therapy with Tavegil can be prescribed if there is a history of the following diseases:

allergic and chronic rhinitis;
conjunctivitis;
various forms of dermatoses of an allergic nature;
angioedema;
food allergies.

In some cases, it can be used as an adjuvant as part of complex therapy for the following diseases:

pneumonia;
arthritis;
obstructive bronchitis;
nephritis;
bronchial asthma.

Indications for use of Tavegil

What are the tablets for, and what are the solution and syrup used for?

The medicine is prescribed for allergic urticaria , hay fever, allergic rhinitis, eczema, pruritic dermatosis , contact dermatitis, drug allergies , allergies to insect bites. Indications for the use of Tavegil are also: hemorrhagic vasculitis , serum sickness, pseudoallergic reaction, anaphylactic shock, acute iridocyclitis .

Contraindications

simultaneous use of monoamine oxidase inhibitors (MAO);
diseases of the lower respiratory tract, including bronchial asthma;
breastfeeding period;
individual intolerance to Tavegil components.

In addition, it is contraindicated to prescribe the solution for intravenous and intramuscular administration during pregnancy, with fructose intolerance and for intra-arterial administration.

Tavegil tablets should not be taken during pregnancy, or in patients with glucose-galactose malabsorption syndrome, severe lactase deficiency, or galactose intolerance.

Age contraindications for prescribing Tavegil to children:

solution: up to 1 year;
tablets: up to 6 years;
syrup: up to 1 year.

According to the instructions, Tavegil is recommended to be prescribed with caution for stenosing gastric ulcers, pyloroduodenal obstruction, prostatic hypertrophy complicated by urinary retention, obstruction of the bladder neck, hyperthyroidism, increased intraocular pressure, arterial hypertension and other diseases of the cardiovascular system.

In addition, the syrup should be used with extreme caution in cases of pyloric stenosis and angle-closure glaucoma.

Tavegil - instructions for use, analogues, price, indications and contraindications

Today we will talk about Tavegil, its instructions for use in allergology (the description of the drug TAVEGIL is based on the officially approved instructions for use).

The drug Tavegyl belongs to the group of antiallergic drugs from histamine H1 receptor blockers and is prescribed to patients to relieve allergy attacks of various origins and intensity.

Release form and composition of the drug Tavegil

Tavegil is available in the form of tablets, syrup for oral use and solution for injection into a muscle or vein.

White tablets in a blister of 5 or 10 pieces in a cardboard box with a detailed description attached. Each tablet of the medicine contains the active ingredient Clemastine 1 mg, as well as a number of excipients - lactose monohydrate, magnesium stearate, corn starch, povidone.

A special syrup form makes it easy to take for children over one year of age.

The injection solution is available in 5 ml transparent glass ampoules in plastic trays of 5 pieces in a cardboard package. Each ampoule of the drug contains 2 mg of the active component - Clemastine, the auxiliary components are ethanol, sorbitol, propylene glycol, water for injection, sodium citrate dihydrate.

Manufacturer: Novartis Consumer Health (Switzerland).

pharmachologic effect

Tavegil has a high level of antihistamine action and prevents the release of active substances from mast bodies (blood cells), which provoke the development of allergic symptoms. Prevents the development of edema by reducing the permeability of microcirculatory vessels.

In addition to the antiallergic effect, it has an anticholinergic, sedative effect, and reduces the permeability of the vascular wall. The drug does not have a hypnotic effect. Tavegil prevents the contraction of smooth muscles and the development of vasodilation caused by the action of histamine.

Clemastine reduces itching, has a local anesthetic effect, inhibits the formation of edema, exudation, and reduces the permeability of the capillary wall. During the experiment, it was found that Tavegil does not have teratogenic, mutagenic or carcinogenic effects. When taking dosages 300 times higher than normal, fertility decreases.

The action begins within half an hour after the first dose, and the peak is reached after 5 hours. Most often, the antihistamine effect lasts more than 12 hours, but sometimes it can last about a day.

Indications for use of Tavegil

The drug Tavegil in the form of tablets and solution is prescribed to patients for the symptomatic treatment of the following allergic reactions:

skin rashes;
angioedema;
hives;
post-vaccination allergic reactions;
rhinitis or conjunctivitis occurring during the period of active dusting and flowering of plants;
contact dermatitis;
year-round rhinitis;
weeping eczema;
atopic dermatitis;
allergic reactions to the administration of medications and food;
allergic reactions to insect bites;
Tavegil in tablet form can be prescribed to patients prone to allergies as a preparation for vaccination.

Tavegil contraindications

Before starting therapy, you should carefully read the attached instructions, since the drug Tavegil has a number of contraindications:

infant period (child's age up to 1 year) for the solution;
a child under 6 years of age for the tablet form of an antihistamine;
pregnancy and breastfeeding;
bronchial asthma with severe attacks and asthmatic status;
increased individual sensitivity to the drug.

Relative contraindications to the administration of the drug are: angle-closure glaucoma, anuria, prostatic hyperplasia, hyperthyroidism, liver and kidney dysfunction, diseases of the cardiovascular system.

According to the instructions, Tavegil is also recommended to be prescribed with caution for:

stenosing gastric ulcer
pyloroduodenal obstruction,
prostate hypertrophy,
complicated by urinary retention,
obstruction of the bladder neck,
increased intraocular pressure,
arterial hypertension and other diseases of the cardiovascular system.

The drug should also be prescribed with caution to patients over 65 years of age.

Use of Tavegil during pregnancy and breastfeeding

The use of Tavegil in the form of injections or tablets at any stage of pregnancy is contraindicated, since there is no clinical experience with its use and it is unknown how treatment can affect the intrauterine development of the fetus.

The active ingredients of the drug can be excreted in breast milk, so Tavegil therapy is not advisable during breastfeeding. If treatment with Tavegil is necessary, a woman should stop breastfeeding.

Side effects of Tavegil

If you follow the dose prescribed by your doctor, side effects are rare. In persons with increased individual sensitivity to the drug or in patients who have been using Tavegil for a long time, undesirable side effects may occur:

from the nervous system - drowsiness, dizziness, lethargy, lethargy, apathy, asthenia, headaches;
from the respiratory system - impaired respiratory function, cough caused by excessive dryness of the mucous membranes;
from the digestive system - dry mouth, thirst, stomatitis, abdominal pain, nausea, vomiting, diarrhea, increased activity of liver transminases;
from the cardiovascular system - decreased blood pressure, tachycardia, heart rhythm disturbances; skin rashes, anaphylactic shock in rare cases, swelling of the mucous membranes;
local reactions during injection - infiltration at the injection site, pain, hematoma.

If the listed side effects occur, treatment with the drug should be stopped and consult a doctor.

Tavegil overdose

To avoid the development of signs of overdose, do not exceed the prescribed dose.

Symptoms of an overdose of Tavegil and antihistamines in general are: drowsiness, heart rhythm disturbances, respiratory depression, acute vascular insufficiency, collapse, loss of consciousness.

If such clinical symptoms appear, you should immediately stop administering the drug and take the patient to a doctor, where he is given symptomatic treatment.

Interaction with other drugs

Tavegil in the form of tablets and solution for injections cannot be prescribed simultaneously with analgesics, sedatives, MAO inhibitors, tranquilizers, and sleeping pills. This drug interaction enhances the therapeutic effect of the latter, which can provoke serious complications.

When Tavegil tablets are prescribed simultaneously with antacids and enterosorbents, the therapeutic effect of antihistamines is reduced, which should be taken into account and a certain time interval must be maintained when taking medications.

Tavegil - analogues

There are no direct analogues of Tavegil, but the following antihistamines have a similar effect:

All of the listed drugs have different composition, dosage and age restrictions, so before changing the prescribed drug, you should definitely consult with your doctor.

Conditions for storage and release from pharmacies

Tavegil can be bought at a pharmacy without a doctor's prescription. The tablets should be stored in a place protected from children for no more than 4 years from the date of manufacture.

The package with ampoules must be kept in a cool, dark place out of the reach of children. The shelf life is indicated on the packaging and is 2 years from the date of manufacture, provided that the ampoules are stored correctly.

Interaction with other drugs

The drug Tavegil in the form of tablets and solution for injections cannot be prescribed simultaneously with analgesics, sedatives, MAO inhibitors, tranquilizers, and sleeping pills. This drug interaction enhances the therapeutic effect of the latter, which can provoke serious complications.

Side effects

Determination of the frequency of adverse reactions: very often (≥1/10); often (≥1/100,

Allergic reactions: rarely - anaphylactic shock.
From the cardiovascular system: rarely - decreased blood pressure (more often in elderly patients), extrasystole; very rarely - palpitations.
From the senses: rarely - impaired clarity of visual perception, diplopia, acute labyrinthitis, tinnitus.
From the urinary system: very rarely - frequent urination, difficulty urinating.
From the hematopoietic system: rarely - hemolytic anemia, thrombocytopenia, agranulocytosis.
Dermatological reactions: rarely - skin rash, photosensitivity.
From the nervous system: often - increased fatigue, drowsiness, sedation, weakness, feeling tired, lethargy, impaired coordination of movements; infrequently - dizziness; rarely – headache, tremor, stimulating effect.
From the digestive system: rarely - dyspepsia, nausea, vomiting, gastralgia; very rarely - constipation, dry mouth; in some cases - loss of appetite, diarrhea.
From the respiratory system: rarely - thickening of bronchial secretions and difficulty in sputum separation, a feeling of pressure in the chest and difficulty breathing, nasal congestion.

Overdose

Symptoms. An overdose of antihistamines can lead to both depressant and stimulating effects on the central nervous system, the latter more often observed in children. Anticholinergic effects may also develop: dry mouth, fixed dilation of the pupils, flushing of blood to the upper half of the body, gastrointestinal disorders (nausea, epigastric pain, vomiting).
Treatment. If the patient does not vomit spontaneously, then it should be induced artificially (only if the patient’s consciousness is preserved). If 3 hours or a little more have passed since taking the drug, it is necessary to perform gastric lavage using a 0.9% solution of sodium chloride and activated carbon. You can also prescribe a saline laxative. Symptomatic therapy is also indicated.

How do allergy sufferers rate Tavegil?

Tavegil, the price of which is 120 rubles. for 10 tablets, it is in higher demand than its analogues (as confirmed by reviews) , although the instructions for use warn of many side effects. The thing is that it acts really quickly and relieves all the symptoms of allergies, from a painful runny nose to a rash. According to patients, its price fully corresponds to its effectiveness.

But the medicine has a significant drawback: it often causes side effects. People complain that after taking it they feel very sleepy, sometimes they experience diarrhea and dizziness. Although Tavegil really works (and almost everyone agrees with this), some believe that it is outdated because it negatively affects performance.

How to take Tavegil

The medication is prescribed for allergic reactions of varying severity. The doctor selects the release form and daily doses on an individual basis. Self-medication is contraindicated because it is harmful to the patient’s health. The course of conservative treatment lasts 7–14 days without interruption . On the recommendation of the attending physician, it is repeated or extended.

Tavegil tablets

The antihistamine is intended for oral administration. The optimal dose for adults is 1 tablet. twice a day - morning and evening, always before meals. According to the instructions, swallow the pill whole, do not chew it, and wash it down with a large volume of water. Dosage for children 6–12 years old – 0.5 tablet. with the same number of daily approaches. The course of treatment is up to 2 weeks.

Tavegil in ampoules

In case of anaphylactic shock, the contents of 1 ampoule (2 ml of solution) are injected into a vein. This procedure is performed twice a day – in the morning and in the evening. In some clinical cases, a diluted composition is used (the concentrate is first diluted with solutions of sodium chlorine or glucose in a ratio of 1:5). For children 6–12 years old, in case of an allergic reaction, an injection of the drug Tavegil is performed intramuscularly, the procedure is repeated twice a day. A single dose is calculated at the rate of 0.025 mcg of solution per 1 kg of child’s body weight. The course of treatment is determined individually.

Syrup

Tavegil for children is often prescribed in the form of a solution. In pediatrics, this is the main or auxiliary therapy for allergic reactions of various origins. This form of medication is approved for children from 1 year of age , the duration of treatment is no longer than 7 days, the number of daily approaches is 2. The recommended dosages depend on the age of the child:

from 1 to 3 years – 2–2.5 ml;
3–6 years – 5 ml;
6–12 years – 5–10 ml;
from 12 and older – 10 ml.

Analogs

If the use of Tavegil causes side effects, or the weekly course does not produce positive results, the doctor introduces a replacement. Below are reliable analogues and their brief characteristics:

Diphenhydramine. These are tablets for oral use and a solution for intravenous administration. A drug with antiemetic, anti-inflammatory, anesthetic, antispasmodic and ganglion-blocking effects for complex treatment. Daily dose – 1 tablet. three times a day.
Suprastin. Solution in ampoules and tablets on blister packs against all types of allergies. According to the instructions, the course of treatment lasts 5 days, daily doses depend on the nature of the pathology and the age of the patient.
Pipolfen. This is a medicine in the form of tablets with antihistamine, hypnotics, and sedative properties. It is also available in the form of a clear solution for intramuscular or intravenous administration. The dosage depends on the patient's age.

Tavegil tablets - instructions for use, analogues and reviews

When taking Tavegil tablets, the instructions for use should be read more than once to understand the need to take the drug and prevent the development of negative consequences.

Tavegil is an antihistamine drug that blocks histamine receptors located in smooth muscle cells, the inner lining of blood vessels and the nervous system.

Antihistamine tablets are intended for the patient to get rid of allergy attacks of various etiologies and intensity. To prevent the condition from getting worse, it is important to take a pill at the first symptoms of an allergy, having first read the instructions for using the antiallergic drug called Tavegil.

General properties of Tavegil tablets

Tavegil is a 1st generation antihistamine with a prolonged effect without a sedative effect. According to the instructions for use, the tablets are based on the pharmaceutical substance clemastine.

In addition to its properties that relieve allergic reactions, clemastine is an m-anticholinergic blocker, acts as a sedative, and reduces the formation of edema, including pulmonary or cerebral edema.

The instructions for use suggest the use of tablets to cure nettle rash, and the instructions also indicate that Tavegil can be used to treat acute or chronic skin inflammation, angioedema, allergic rhinitis and other types of allergic reactions.

Tavegil injections

Chemical components, production form and packaging of the drug Tavegil

The instructions for use state that the active pharmacological substance in Tavegil is clemastine, and hydrofumarate is an additional pharmacological substance.

1 tablet contains 1.34 mg of clemastine hydrofumarate. In addition to hydrofumarate, tablets include: lactose with a water molecule (107.66 mg), corn starch (10.08 mg), talc (5 mg), polyvinylpyrrolidone (4 mg), magnesium salt with stearic acid (1.2 mg) .

Tavegil can be found in pharmacies in PVC packs of 5 tablets - 2 blisters, 10 tablets - 1 blister and 10 tablets - 2 blisters.

Tavegil is available not only in tablets. You can also buy Tavegil syrup, drops and ointment, as well as an injection solution at the pharmacy.

In order to stop antihistamine receptors with tablets, solutions, ointments or drops of Tavegil, you must also use the instructions for use.

Tavegil syrup

Pharmacological index

Tavegil is a medicine, the use of tablets of which is necessary to eliminate itching of allergic etiology. The tablet blocks the action of serotonin, histamine, and bradykinin in the blood.

Reading the instructions, you can understand that these components are responsible for the hypersensitivity of the immune system upon contact with an irritant.

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The instructions state that the use of the main chemical substance clemastine reduces the penetration of oxygen and nutrients from blood vessels and capillaries, as a result of which tissue edema does not develop.

According to the instructions for use, clemastine also prevents the enlargement of arteries and capillaries. The use of Tavegil tablets does not have a sedative effect.

The tablets are effective half an hour to an hour after taking them, their work lasts more than 8 hours. The kidneys mostly remove Tavegil from the body along with urine.

In accordance with the instructions for use, the unchanged substance in the urine can be detected in small proportions. The instructions warn nursing mothers that during breastfeeding a small dose of clemastine may pass into milk.

Tavegil tablets instructions for use for adults

Pharmacokinetic processes

Pharmacokinetic processes include absorption, distribution, metabolism and excretion of Tavegil.

After taking the tablet, Tavegil is completely absorbed from the digestive tract. The highest concentration in blood plasma is achieved after 2.5-5 hours, the greatest effect occurs within 4-8 hours.

Clemastine binds to plasma proteins by 90-95%, passes through the barrier between the circulatory system and the main part of the nervous system, penetrating into breast milk in a small volume.

The tablets pass through the liver. 40-60% of metabolic products are excreted in the urine. Tavegil is excreted in 2 phases.

Tavegil tablets composition

In what situations should you take Tavegil tablets?

The use of tablets is effective for the following pathologies:

hay fever;
nettle rash;
itching, burning, dermatosis;
acute and chronic inflammation of the skin;
hypersensitivity to medicinal components;
itching, swelling due to an insect bite;
Quincke's edema;
diffuse inflammatory process of the bronchial mucosa;
inflammation of the mucous membrane of the eye;
runny nose with paroxysmal sneezing.

In what cases is the use of tavegil tablets undesirable?

According to the instructions, Tavegil is prohibited from taking under the following conditions:

Particular sensitivity to clemastine and other components of Tavegil;
Respiratory diseases, including status asthmaticus;
Taking antidepressants;
Individual intolerance to Tavegil tablets;
Children under 6 years of age;
Pregnancy and lactation period.

The use of tablets is recommended with caution in patients with defects in the gastric mucosa, pyloroduodenal stenosis, patients with urinary tract obstruction, people with an enlarged prostate who have symptoms of urinary retention, and the instructions for use of Tavegil warn that tablets are undesirable for patients with glaucoma, high level of thyroid-stimulating hormone, diseases of the circulatory system (one of them is hypertension).

Contraindications for Tavegil tablets

Brief instructions for using Tavegil tablets

The instructions say that Tavegil tablets are taken 20-30 minutes before meals, washed down with plenty of water. For children over 12 years of age, the instructions recommend taking 1 tablet twice a day, preferably before breakfast and dinner.

If the therapeutic effect is not achieved, the instructions warn that the daily dose of Tavegil may be increased to 6 tablets.

Children 6-12 years old are allowed to use Tavegil 0.5-1 tablet 2 times a day. The tablets are contraindicated for use in children under 6 years of age.

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If it is necessary to use Tavegil as an injection intravenous or intramuscular solution, then Tavegil is injected according to the instructions, 2 mg in the morning and evening.

The instructions indicate that the use of the drug is not recommended for children from 0 to 12 months. Judging by the instructions, children over 1 year to 12 years old are given injections of 12.5 mcg per 1 kg of the child’s body weight 2 times a day.

As a prophylactic agent, 2 mg of clemastine is administered once a day. The solution must be diluted with 0.9% sodium chloride.

The instructions notify that Tavegil tablets are harmful for pregnant and lactating women.

Active ingredient of Tavegil tablets

Negative effects from the drug Tavegil

When using tablets, negative consequences are possible that affect the functioning of important organ systems.

Negative effects of tablets on the central nervous system:

general weakness;
desire to sleep;
sedation;
feeling of overwork;
decreased reaction speed;
motor disorders, loss of strength in the limbs;
feeling dizzy;
headache;
trembling of limbs;
stimulating effect of the drug.

Negative effects of tablets on the gastrointestinal tract:

indigestion;
semi-fainting state;
vomit;
cramping pain in the stomach;
difficulty emptying;
dryness of the oral mucosa;
refusal to eat;
diarrhea.

Negative effects of Tavegil on the respiratory system:

accumulation of mucus in the bronchi and problems with expectoration of mucus;
chest discomfort, shortness of breath;
the nose is stuffy, but there is no runny nose.

Negative effects of Tavegil on the heart and blood vessels:

persistent or regular decrease in blood pressure;
Heart arythmy;
increased heart rate.

Negative effects of Tavegil on vision and hearing:

blurred visual perception;
double vision;
acute inflammation of the inner ear;
sensation of noise, ringing in the ears.

Negative effects of tablets on the urinary system:

frequent emptying of the bladder;
difficult urine output.

Undesirable effects of tablets on the circulatory system:

destruction of red blood cells;
decreased platelet count;
decrease in leukocyte levels.

An overdose of tablets has a depressing effect on the central nervous system and other organs, which is noticeable in most cases in children. The instructions for use also indicate that the development of syndromes inherent in medications with an anticholinergic effect is possible:

severe dryness of the oral mucosa;
pupils with increased diameter;
rushes of blood to the face and head;
dysfunction of the digestive tract - discomfort in the epigastric region, pain in the stomach, eruption of stomach contents.

In case of an overdose of tablets, it is necessary to artificially induce vomiting (if you do not vomit spontaneously). If the drug was consumed more than 4 hours ago, it is advisable to rinse the stomach using saline solution. A salt-based laxative will also help. If an overdose occurs, symptomatic therapy is effective.

Tavegil tablets and analogues

Analogs of Tavegil tablets

There are absolute and relative analogues of Tavegil tablets. But it is necessary to remember that if the doctor prescribed a patented drug, you need to be careful when replacing it with other drugs and strictly follow the instructions for use.

Some generics have exactly the same properties as Tavegil tablets, but we must not forget that each medicine has its own undesirable consequences and what is suitable for one patient is contraindicated for another patient.

The use of analogues must be approved by the physician treating the patient.

Generic Tavegil tablets:

Diphenhydramine;
Eden;
Suprastin;
Cetrin;
Zyrtec;
Erius;
Loratadine and other known antihistamines.

Dosage of Tavegil

Average cost of Tavegil tablets

Tavegil tablets cost differently depending on the region. So, 20 tablets of 1 mg each cost approximately 167 rubles, 10 tablets of 1 mg each can be bought on average for 136 rubles. The price for 5 ampoules ranges from 175 rubles.

Rules for purchasing Tavegil tablets at a pharmacy

When purchasing Tavegil tablets, you do not need to provide a prescription from a doctor, but the pharmacist must warn you that you need to read the instructions for use before taking it.

Storage mode

Storage of Tavegil tablets requires that the temperature should not be higher than 30 degrees. The drug should be stored in a place where children cannot reach. Shelf life is no more than 2 years.

Reviews

Maria, 32 years old

The doctor prescribed the use of Tavegil tablets for eczema. After taking two pills, I felt drowsy. The instructions mention this side effect. Despite this, the drug was able to eliminate the itching.

Ekaterina, 23 years old

My husband and I bought shish kebab at the store and ate a piece, but my husband’s lower lip and eyelid were swollen. In my purse I found a Tavegil tablet, the use of which helped my husband feel better.

Andrey, 45 years old

I am an allergist. Increasingly, children with skin allergies are being brought to appointments. I prescribe Tavegil according to the instructions - it helps. But children under 6 years old cannot take Tavegil in tablets - only solutions.

Marina, 35 years old

The other day my son was stung on the palm by a bee. The wrist is very swollen. There is always a place for Tavegil in the home medicine cabinet. The use of the pill alleviated the son's condition, but there was a slow reaction.

Source: //yaallergik.com/antigistaminnye-preparaty/tabletki-tavegil

What place does Tavegil occupy in the antihistamine family?

Tavegil is a systemic antihistamine that is used to eliminate allergy symptoms. Made in Austria. Its action is due to the presence of clemastine in the active substance. It inhibits the synthesis of histamine, a substance that is produced by the body upon contact with allergens and leads to allergic reactions: itching, hyperemia, irritation, swelling and bronchospasm. Tavegil eliminates all this.

The medicine is a representative of the first generation. These are quite old drugs: they appeared back in 1936. They act quickly and give a pronounced effect; they are used if the patient’s condition requires emergency care. But they provide only short-term results that last no more than 8 hours. Representatives of this group have several disadvantages: a strong “inhibitory” effect, many adverse reactions; they must be taken frequently and in large doses. Such medications produce a noticeable hypnotic effect, so they are not suitable for patients whose activities require concentration.

special instructions

While taking the drug, it is strongly recommended to refrain from driving vehicles and other complex mechanisms, since Tavegil temporarily impairs vision and the ability to concentrate.
The product should not be used for at least 72 hours before allergy skin testing, as it may significantly distort the results.
Enhances the effect of neuroleptics (antipsychotics), sleeping pills, sedatives, and anticholinergic drugs. Simultaneous use with MAO inhibitors is not allowed.
Tavegil tablets contain lactose, so the drug is not recommended for patients suffering from rare congenital diseases associated with impaired galactose tolerance, severe lactase deficiency and glucose-galactose malabsorption.