Arbidol tablets 50 mg: instructions for use

Arbidol for COVID-19? The first publications regarding the effectiveness of Arbidol against coronavirus began to appear in the Chinese media in early February. On the 6th, a team of virologists from Zhejiang University, led by Professor Li Lanjuan, completed another study. Its essence was to determine the effectiveness of the combination of antiviral drugs Arbidol and Darunavir (a drug for the treatment of HIV) in the treatment of COVID-19. Upon completion of the work, the professor called for Arbidol to be added to the list of drugs recommended to combat SARS-CoV-2, which was done on February 18.

The Bell was the first Russian media outlet to draw attention to this, although the fact that the drug was called Abidol was a little alarming. It later turned out that this was due to the use of online translators, which, when translating from Chinese into English, lost one letter from the name.

Studies of the antiviral drug Arbidol did not confirm scientists’ hypothesis about its effectiveness against a new type of coronavirus

At the same time, Insider wrote that the Chinese authorities plan to test Arbidol in order to assess whether it will help with coronavirus, as well as to determine how best to take the drug and other possible nuances. At the same time, this medicine has already been recommended for use by patients with COVID-19, since a specific remedy for the pathogen has not yet been created.

Arbidol for coronavirus: myths and reality

Arbidol has been called in the media an effective cure for coronavirus, but in fact it is premature to make such an encouraging statement, although there are real facts:

• it is an antiviral drug that prevents infection and alleviates the course of infectious diseases;
• acts on coronaviruses, that is, not only on the new one;
• previously used to treat similar viral pneumonia;
• since there is no proven effectiveness for any of the medications and vaccines, the WHO allows doctors to prescribe different drugs to choose the best one;
• Arbidol is among the medications that are being studied, but there is no final conclusion;
• the decision on the appropriateness of use in each specific case is made only by the doctor;
• It is not yet known what will be more beneficial or harmful with coronavirus.

Composition per capsule

Active substance:

umifenovir hydrochloride monohydrate (in terms of umifenovir hydrochloride) – 100 mg.

Excipients: core: potato starch – 30.14 mg, microcrystalline cellulose – 55.76 mg, colloidal silicon dioxide (Aerosil) – 2.0 mg, povidone K 25 (kollidon 25) – 10.1 mg, calcium stearate – 2 .0 mg.

Hard gelatin capsules No. 1:

Body: titanium dioxide (E 171) – 2.0000%, gelatin – up to 100%.

Cap: titanium dioxide (E 171) – 1.3333%, sunset yellow dye (E 110) – 0.0044%, quinoline yellow (E 104) – 0.9197%, gelatin – up to 100%.

Description

Hard gelatin capsules No. 1. The body is white, the cap is yellow. The contents of the capsules are a mixture containing granules and powder from white to white with a greenish-yellowish or creamy tint.

Pharmacotherapeutic group: antiviral agent

ATX code: J05AX13

Pharmacological properties

Pharmacodynamics. Antiviral agent. Specifically suppresses in vitro influenza viruses A and B (Influenzavirus A, B), including highly pathogenic subtypes A(H1N1)pdm09 and A(H5N1), as well as other viruses that cause acute respiratory viral infections (ARVI) (coronavirus associated with severe acute respiratory syndrome (SARS), rhinovirus (Rhinovirus), adenovirus (Adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (Paramyxovirus)). According to the mechanism of antiviral action, it belongs to fusion inhibitors, interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect and increases the body's resistance to viral infections. It has interferon-inducing activity - in a study on mice, the induction of interferons was noted after 16 hours, and high titers of interferons remained in the blood up to 48 hours after administration. Stimulates cellular and humoral immune responses: increases the number of lymphocytes in the blood, especially T-cells (CD3), increases the number of T-helpers (CD4) without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates the phagocytic function of macrophages and increases the number of natural killer (NK) cells.

Therapeutic effectiveness for viral infections is manifested in a decrease in the duration and severity of the disease and its main symptoms, as well as in a decrease in the incidence of complications associated with viral infection and exacerbations of chronic bacterial diseases.

In the treatment of influenza or ARVI in adult patients, a clinical study showed that the effect of the drug Arbidol® in adult patients is most pronounced in the acute period of the disease and is manifested by a reduction in the time for resolution of symptoms of the disease, a decrease in the severity of manifestations of the disease and a reduction in the time for elimination of the virus. Therapy with Arbidol® leads to a higher frequency of relief of disease symptoms on the third day of therapy compared to placebo. 60 hours after the start of therapy, the resolution of all symptoms of laboratory-confirmed influenza was more than 5 times higher than in the placebo group.

A significant effect of the drug Arbidol® on the rate of elimination of the influenza virus was established, which, in particular, was manifested by a decrease in the frequency of detection of viral RNA on the 4th day.

Refers to low-toxic drugs (LD50 > 4 g/kg). Does not have any negative effects on the human body when administered orally in recommended doses.

Pharmacokinetics. Quickly absorbed and distributed throughout organs and tissues. The maximum concentration in blood plasma is reached after 1.5 hours. Metabolized in the liver. The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in small amounts by the kidneys (0.12%). During the first day, 90% of the administered dose is eliminated.

Pharmacokinetics and pharmacodynamics

In the human body, the active substance is quickly absorbed by the digestive system. The maximum concentration of umifenovir is achieved after 1.2-1.5 hours, depending on the concentration of the drug. The peculiarity of the drug is that it is quickly distributed throughout the organs and tissues, thereby providing a rapid therapeutic effect. Metabolism is carried out in the liver - slightly less than half is excreted in its original form. The maximum amount is excreted in the bile, and slightly - in the kidneys. During the first 24 hours after starting to take the drug, it is excreted in amounts up to 90%.

Indications for use

• Prevention and treatment in adults and children: influenza A and B, other acute respiratory viral infections.
• Complex therapy of recurrent herpes infection.
• Prevention of postoperative infectious complications.
• Complex therapy of acute intestinal infections of rotavirus etiology in children over 6 years of age.

Contraindications

Hypersensitivity to umifenovir or any component of the drug; children under 6 years of age. First trimester of pregnancy. Breastfeeding period.

With caution: Second and third trimesters of pregnancy

Use during pregnancy and breastfeeding

In animal studies, no harmful effects on pregnancy, embryonic and fetal development, labor or postnatal development were identified. The use of Arbidol® in the first trimester of pregnancy is contraindicated. In the second and third trimester of pregnancy, Arbidol® can be used only for the treatment and prevention of influenza and if the expected benefit to the mother outweighs the potential risk to the fetus. The benefit/risk ratio is determined by the attending physician.

It is not known whether Arbidol® passes into breast milk in women during lactation. If it is necessary to use the drug Arbidol®, you should stop breastfeeding.

Interaction with other drugs

When prescribing Arbidol with other drugs, no negative effects were noted.

Overdose

cases of overdose with Arbidol .

Storage conditions

List B. The drug Arbidol should be stored in a dry place, protected from light.

Release form

Capsules, film-coated tablets

Side effects

, allergic reactions may occur during treatment with this drug.

Price for Arbidol against coronavirus

One package of Arbidol in capsules of 20 pieces and 100 mg costs approximately 520 rubles; for the treatment of coronavirus, at least 10 packs may be needed, but the decision to use this particular drug is made only by a doctor after an examination. Arbidol Maximum has exactly the same average cost, since the package contains 10 capsules of 200 mg each.

Action of Arbidol

Umifenovir is registered in the list of drugs as an antiviral and immunomodulatory agent. After swallowing, the tablet dissolves in the intestines. The components of the drug penetrate the bloodstream and distribute into the tissues. Umifenovir has demonstrated its effectiveness against influenza A and B viruses. Arbidol also fights other pathogens of acute respiratory infections. The therapeutic effect of the drug depends on the severity of the patient’s condition and the prescribed dosage. A viral infection begins with infection of the mucous membrane of the respiratory tract. The infectious agent, together with saliva, enters the integumentary tissue and penetrates the cell. Viral particles gradually accumulate: new pathogens are released into surrounding tissues and quickly spread throughout the body. Umifenovir prevents the fusion of viral particles with cells, thereby stopping the development of the infectious process.

Other properties

• Improving immune function. The body's defense system needs special substances to fight infection. In response to viral invasion, white blood cells and other cells release interferons that prevent pathogens from multiplying. Umifenovir is an external interferon inducer. Prevention can be done with this medicine.
• Antioxidant effect. Any disease weakens the protective properties of tissues. Dangerous forms of oxygen begin to damage healthy cells, causing the symptoms of the disease to intensify. Antioxidants strengthen cell membranes.
• Cleansing the body of toxins. Harmful substances enter the blood after the destruction of viral particles. The drug significantly reduces the number of viruses and alleviates the symptoms of intoxication.
• Reducing the likelihood of complications. Improper treatment of ARVI leads to bacterial infection. Using antiviral drugs helps protect organs from other pathogens.
• Reducing the duration of rehabilitation. Symptoms of weakness and fatigue often persist after recovery. Taking umifenovir quickly restores the body's resources.

Antiviral medications rarely speed up recovery. The main goal is to eliminate symptoms.

Adverse reactions

The active component of the drug rarely causes side effects. This non-toxic substance improves the condition of tissues during illness. Only minor complaints are possible. Rare side effects during treatment:

The medicine must be prescribed by a doctor

• Headache.
• Nausea and vomiting.
• Allergic reaction.

Intolerance to a drug component is the most serious complication. If rashes appear on the skin during therapy, you should stop taking the pills and consult a doctor.

Instructions for use of Arbidol (Method and dosage)

Capsules and tablets should be taken orally before meals.

Arbidol capsules, instructions for use

Arbidol capsules should be taken in a dose that depends on age. Thus, children from 3 to 6 years old are prescribed 50 mg, children from 6 to 12 years old take 100 mg, patients over 12 years old are prescribed 200 mg of Arbidol (2 capsules 100 mg or 4 capsules 50 mg). Children under 3 years of age are a contraindication for taking the drug.

To ensure nonspecific prophylaxis after contact with patients with viral infectious diseases, 10-14 days are used at the dosage indicated above.

The same dosage of Arbidol is prescribed during an epidemic of ARVI and influenza , but the medicine must be taken 1 dose twice a week for three weeks.

For treatment purposes, patients with influenza and ARVI are prescribed 200 mg 4 times a day (adults and adolescents from 12 years of age), 100 mg four times a day (from 6 to 12 years), 50 mg four times a day (from 3 to 6 years of age). years). Treatment lasts 5 days.

If complications develop with these diseases, the drug should initially be taken in the above dosage for 5 days, then for 4 weeks, adult patients take 200 mg of Arbidol once a week, children from 6 to 12 years old take 100 mg once a week. week, from 3 to 6 years - 50 mg once a week.

For the treatment of SARS, adult patients and adolescents over 12 years of age are prescribed 200 mg of the drug twice a day, therapy lasts 8-10 days.

Arbidol tablets, instructions for use

Children from 3 to 6 years old receive a single dose - one 50 mg tablet, children from 6 to 12 years old - 100 mg of Arbidol, adults - 200 mg.

People who are in contact with patients with influenza or ARVI, for the purpose of prevention, receive the above dose of the medicine once a day for 10-14 days.

During an epidemic of influenza or acute respiratory viral infection, people are prescribed the drug in the same dose twice a week for 3 weeks for prevention.

In order to prevent complications after surgical interventions, the same dose of Arbidol is prescribed two days before surgery, then the patient should take the drug 2-5 days after surgery.

For the treatment of ARVI and influenza without complications, the drug in tablets is prescribed to patients from 3 to 6 years old, 50 mg, to patients from 6 to 12 years old, 100 mg, to people over 12 years old and adults - 200 mg four times a day. Treatment lasts 5 days; if complications occur, the drug is continued for another 4 weeks at the indicated single dose once a week.

It should be noted that the instructions for use of Arbidol for children with other diseases are determined by the doctor individually.

Arbidol can be used during pregnancy only after a doctor has prescribed it at the dose prescribed by him.

Arbidol and coronavirus – research

After the Chinese organization for the fight against COVID-19 included the drug in the list of potential drugs to test Arbidol, efficacy studies began to be carried out during treatment. The experiment involved 86 patients whose disease was mild to moderate in severity. Of these, 35 people took Arbidol against coronavirus, 34 people were treated with a combination of LPV/r drugs, and the remaining 17 did not receive antiviral drugs.

As a result of the study, it was found that no changes in the health status of patients taking Arbidol against the identified coronavirus were observed. In this regard, work to find an effective drug for COVID-19 continues. And to this day they have not been found.

Efficacy against coronavirus

Coronavirus infection is one of the dangerous pathologies. It affects each person differently. Some people are only carriers, others suffer from signs of ARVI. Digestive and respiratory diseases occur less frequently. Therefore, it is necessary to understand whether Arbidol helps in the prevention and treatment of coronavirus, and whether complications can be prevented.

Arbidol helps in eliminating viruses spreading through the respiratory and digestive system.

Clinical trials for antiviral drugs are just underway. There is no reliable data on any drug, so it is impossible to accurately predict the effect of Arbidol.

Doctors recommend it for mild cases of the disease to stimulate immune function. This is not a myth or a lie. Arbidol helps eliminate the following consequences of the disease:

• suppression of the immune system;
• severe cough that irritates the trachea;
• intoxication of the body, leading to weakness, aching muscles and joints;
• spread of the microorganism throughout most internal tissues, which can cause cardiovascular, respiratory, and digestive pathologies.

If antiviral drugs are not used, complications occur more often. When it comes to coronavirus infection, the medicine does not kill it directly. It helps support the immune system, which independently fights the disease.

Arbidol: instructions, composition, indications, action, reviews and prices

Instructions for use
Arbidol is the most popular domestic antiviral drug. The drug is used for the prevention and treatment of infectious diseases of the respiratory tract. The standard indication for the use of Arbidol is influenza. The active component of the drug suppresses the proliferation of viruses in the body, eliminates the symptoms of the disease and improves immune function. The low risk of side effects allows the medicine to be prescribed to children and adults.

Treatment of viral infections is often difficult. Complex medications are needed to eliminate the cause of the disease and alleviate the patient’s condition. Arbidol is suitable for the symptomatic and etiological treatment of ARVI.

Use for prophylactic purposes

The instructions say that to prevent viral diseases during an epidemic, arbidol should be used once every two weeks in a therapeutic dose (for children under six - 1 tablet of 50 mg, 6-12 years - 2 tablets, for adults - 4 tablets) twice a week within three weeks.

This is not a vaccine; antiviral prophylaxis does not provide any guarantee that a person will not become infected. But in combination with other precautions and prevention measures, the use of the drug is justified.

Medicines > Arbidol for children

Brief description : Arbidol belongs to the group of allopathic antiviral and immunomodulatory chemotherapy drugs. Available in the form of yellow gelatin capsules, or in the form of biconvex tablets with a shell and white or white with a creamy tint. Capsules contain 50 or 100 mg of active ingredient, tablets contain 100 or 200 mg of active ingredient. Packaging: capsules - polymer jars, tablets - blister plates in cardboard packaging (form of release and packaging materials depend on the manufacturer).

Age restrictions : Currently, Arbidol is recommended for use in adults and children over three years of age, since it is assumed that taking tablet forms is difficult for children under this age. Previously, the drug was recommended for children starting from two years of age.

Composition and type of dispensing in pharmacies : the active ingredient of Arbidol is the hydrochloride of ethyl ester 6 bromine, 5 hydroxy, 1 methyl, 4 dimethylaminomethyl, 2 phenylthiomethyl, indole, 3 carboxylic acid. Excipients: modified starch, microcrystalline cellulose, magnesium salt of stearic acid, polyvinylpyrrolidone, opadry-2, lactose.

Indications for use : • Prevention and treatment of acute viral respiratory tract infections (influenza, parainfluenza, respiratory syncytial virus, infectious mononucleosis, adenovirus, herpes, etc.); • Prevention and treatment of acute viral infections of the gastrointestinal tract (enetrovirus, rotavirus, etc.); • Treatment of infectious pathology in secondary immunodeficiency conditions; • An integrated approach to the treatment of chronic respiratory diseases, as well as often recurrent herpetic infections.

Pharmacological action : 1. Arbidol hydrochloride blocks the hemagglutinin protein of the viral envelope, which is responsible for the sedimentation of the virus on the cell wall and for the penetration of the virus into the cell. Thus, Arbidol prevents the multiplication of the virus in the epithelial cells of the respiratory or gastrointestinal tract. 2. Arbidol hydrochloride in the first phase of action stimulates the production of endogenous interferon, which contributes to the stimulation of T-cell and phagocytic immunity. This mechanism determines the immunomodulatory effect of Arbidol. The combination of these two mechanisms of action leads to an easier course of viral and bacterial infections (the severity of intoxication syndrome decreases) and reduces the likelihood of complications. Arbidol is well absorbed from the gastrointestinal tract, and already 90 minutes after taking a 100 mg tablet/capsule, the concentration of the drug in the blood reaches its maximum values. Has a short period of distribution to organs and tissues. Partially processed in the liver (39%), partially excreted unchanged (40%) with bile, and 21% of the drug is excreted by the kidneys. Within 24 hours after administration, 90% of the dose taken is eliminated. The drug is low toxic, the average lethal dose is at least 4 g/kg body weight

Instructions for use : • For therapeutic purposes, adults and children over 12 years of age are prescribed Arbidol 200 mg four times a day before meals, at regular intervals. For children aged 6-12 years, the drug is prescribed 100 mg four times a day, for children aged three to six years - 50 mg according to the same regimen. This course of treatment lasts five days, after which the drug intake is reduced to once a day while maintaining the age-specific single dose, and the course of treatment continues for another 28 days. • For prophylactic purposes, Arbidol is prescribed once a day, before meals: people over 12 years old - 200 mg, from 6 to 12 years old - 100 mg, from 3 to 6 years old - 50 mg. If the drug is used for prophylaxis in direct contact with a person suffering from ARVI, then taking the drug according to this regimen should be daily and last one and a half to two weeks. If the drug is used for prophylactic purposes during an epidemiologically dangerous period, then Arbidol can be used 2 times a week for three weeks in compliance with the above doses.

Number of application courses

Many infectious pathologies are prone to relapse. But this does not apply to covid 19. This disease occurs once, after its completion a stable immunity is formed. Antibodies remain in the body, so the next time you come into contact with an infected person, the disease will not form again. This means that Arbidol is used only once against coronavirus infection. But they use the entire course prescribed by the attending physician.

There are many other viral pathologies in nature. Among them are ARVI, influenza, herpes, adenovirus, and rotavirus. Arbidol has an effect against all these pathogenic microorganisms. Therefore, after completing treatment for coronavirus infection, it can be used again, but at least 2-3 months must pass, otherwise there may be a risk of viral resistance, which will lead to complications of the pathology, the development of bronchitis or pneumonia.

Arbidol is a potent antiviral drug. Therefore, it is recommended to use it strictly according to the prescribed course of treatment and dosage. Then there will be better effectiveness and influence on the disease. But side effects may occur if the drug is used incorrectly. Therefore, it is better to consult with a therapist, pulmonologist, or infectious disease specialist. Proper treatment is the key to a quick recovery.

Indications for use of Arbidol

The product is used for the prevention and treatment of viral diseases. Timely taking of the tablets helps protect the mucous membranes from the invasion of pathogens. Doctors recommend taking the pills before the cold season begins. Completing a course of drug therapy allows the body to accumulate protective proteins required to suppress viral replication. Treatment of infection with Arbidol can be carried out at any stage. The optimal dosage of the drug is selected.

Main indications

• Flu. This pathology is manifested by fever, cough, headache, chills, weakness and other unpleasant symptoms. The gateway to infection is the mucous membrane of the throat. Gradually, pathogens spread throughout the body.
• Other acute respiratory viral infections: bronchitis, tracheitis, pharyngitis and pneumonia.
• Complications of viral pathologies. We are talking about bacterial and fungal infections.
• Stomach flu. Symptoms of the pathology include diarrhea, flatulence, fever and abdominal pain.
• Chronic herpes. Herpes infection is resistant to basic treatments. Arbidol reduces the risk of relapse.
• Congenital or acquired immunodeficiency, characterized by a high risk of developing ARVI.

Umifenovir is also used for prophylactic purposes. This is the drug of choice for the prevention of seasonal respiratory infections. Sometimes the medicine is used in the postoperative period to prevent infectious complications.

When is analog required?

There are cases when Arbidol is not recommended for patients, for example, with individual intolerance. Then you need to choose an analogue that will have good effectiveness against coronavirus infection. It may have more widespread side effects, but the doctor needs to prevent the spread of covid-19, so it is acceptable. There are the following cases when the doctor is looking for a replacement for Arbidol:

• presence of contraindications;
• development of a side effect in the form of an allergic reaction on the skin and mucous membranes;
• low efficiency with the continued spread of coronavirus to neighboring organs and tissues.

The drug is selected from the list recommended by the Ministry of Health. If the patient's condition is mild, Ingavirin is suitable. It has a mild effect on the body, but destroys part of the viral infection. It contains a different active ingredient, so side effects may not occur.

Self-selection of medication for covid 19 is prohibited; to determine the right drug, preliminary tests must be carried out through a doctor.

If the patient's condition progresses from mild to moderate or severe, hospitalization may be required. They call an ambulance. In a clinical setting, doctors use medications prescribed according to the protocol. They are toxic to the body, but have a better effect.

Properties of the drug

Many people are interested in the question of whether Arbidol helps with temperature or not. To understand, you need to familiarize yourself with the principle of action of the drug. Penetrating into the body, it blocks the growth of viruses, thereby reducing the risk of development several times.

In addition, Arbidol has other properties:

• activates the growth of immune cells;
• increases the body's protective functions;
• accelerates the healing process;
• reduces the risk of complications and development of diseases into a chronic form.

Before using Arbidol, you should consult a doctor. Do not take the drug if you are hypersensitive to the components of the composition. During pregnancy and breastfeeding with fever, runny nose or cough, you can take Arbidol in the 2nd and 3rd trimesters.

What is stronger Arbidol or Anaferon

The homeopathic remedy Anaferon is prescribed for colds; it is also suitable for strengthening the immune system. However, the drug does not have an antiviral effect. When treating pathologies, its use is effective only in the initial stages of the disease.

The drug Arbidol perfectly fights viruses, so in case of viral diseases it is better to opt for it, it is more effective.

Both medications are recommended to be taken together with other medications if a person suffers from a serious illness. But Anaferon and Arbidol are excellent for use for preventive purposes, as they do not harm the body.

Before starting to take Arbidol, it is recommended that you carefully read the instructions included with the drug.

Arbidol - what kind of drug is it?

Arbidol, or as it is called by its active ingredient, the drug Umifenovir, is an effective antiviral agent. The drug not only has a detrimental effect on viruses, but also has a pronounced immunomodulatory effect. This is achieved by stimulating humoral and cellular reactions of the immune system. As a result of taking the drug, there is a significant increase in the body's resistance to viral infections.

As doctors' observations show, Arbidol also helps combat the negative consequences of viral diseases. Patients who took it noted:

• reducing the risk of complications after influenza;
• reducing the frequency of periods of exacerbation of chronic diseases;
• normalization of immunological parameters.

Arbidol - composition

Arbidol and Umifenovir are available in the form of drops and powder. Inside the capsules there are white granules with a creamy tint. This is umifenovir hydrochloride, the main active ingredient of the drug. In addition to it, the composition contains a number of other chemicals that are auxiliary:

• potato starch;
• silica;
• cellulose;
• calcium stearate;
• povidone.

What do Ingavirin and Arbidol have in common?

Both drugs exhibit an antiviral effect and act on the same microorganisms, are highly effective and non-toxic. The maximum concentration of both Arbidol and Ingavirin in the blood is achieved in 1-2 hours, which determines their high effectiveness. Only Arbidol is suitable for use by adults and children over 2 years old. Ingavirin is recommended exclusively for adults and children, but only as prescribed by a doctor and taking into account effectiveness. Side effects for 2 drugs are minimal and are limited mainly to allergic reactions.

Important! The use of Arbidol and Ingavirin by pregnant and lactating women is prohibited.

Side effects and special instructions

Arbidol is very well tolerated and does not interact dangerously with any other medications. In medical practice, the side effects of Arbidol and cases of overdose have never been recorded to date. During the period of prophylactic use of the drug and treatment of acute respiratory viral infections, you can drive a car and perform work that requires mental stress and prolonged concentration - it has been proven that Arbidol does not reduce concentration.

Meanwhile, scientific discussions and medical disputes regarding the mechanism of its action and the appropriateness of use do not subside around this drug. It is believed that Arbidol has been repeatedly lobbied by pharmaceutical corporations and governments of developed countries, including the USA and Russia. Many experts question the effectiveness of Arbidol, but there are also doctors who definitely recommend it to their patients, based on the successful practice of using it during seasonal cold epidemics.

Arbidol's analogs

When solving the problem of what can replace Arbidol, you should consult a pharmacist or doctor.

Since the drug is used for colds, medications that relieve symptoms can also be considered analogues. These are antipyretic single drugs Ibuklin, Nurofen, Paracetamol, Panadol, Efferalgan, as well as complex drugs Rinza, Fervex, Theraflu.

In fact, real analogues of Arbidol are antiviral drugs with different mechanisms of action.

Among Arbidol's analogues, homeopathic remedies for the treatment of influenza and other viral respiratory infections, for example, Oscillococcinum, Anaferon, Aflubin, occupy not the least place.

A list of main analogues with different active ingredients and prices is presented in the table

Isoprinosine

Manufacturer: Teva, Israel
Release form: tablets

Active ingredient: Inosine pranobex

Synonyms: Groprinosin, Normomed

The analogue Isoprinosine is effective not only against the influenza virus. The drug is used to treat herpes, herpes zoster, chickenpox, measles and cytomegalovirus infection.

Viferon

Manufacturer: Feron, Russia
Release form: ointment and gel, rectal suppositories

Active ingredient: Interferon alpha

Synonyms: Altevir, Genferon, Grippferon, Reaferon

The analogue of Viferon in the form of a gel and ointment is applied to the nasal mucosa; it can be taken either instead of Arbidol or in combination with it - in the form of complex therapy.

This analogue is approved during pregnancy and for small children from the age of six months.

Polyoxidonium

Manufacturer: Petrovax, Russia
Release form: tablets, rectal and vaginal suppositories, lyophilisate for solution preparation

Active ingredient: Azoximer bromide

The Polyoxidonium analogue has a complex effect: in addition to immunomodulating, it is also anti-inflammatory, detoxifying and antioxidant.

Thanks to the complex action of the Polyoxidonium analogue, the range of its use is very wide - it is used not only for viral, but also bacterial and fungal infections, as well as for regeneration in various injuries, to relieve complications after radiation therapy for cancer patients.

Broncho-munal

Manufacturer: Sandos, Slovenia
Release form: capsules

Active ingredient: Lysates of 5 bacteria

Synonyms: Broncho-Vaxom

The Broncho-munal analogue consists of lysates of the five most common bacteria that cause infectious diseases of the respiratory system, acts like a vaccine - it enhances the body’s protective properties not only against viruses, but also against bacteria.

Acyclovir

Manufacturer: Vertex, Ozone, Tatkhimfarmpreparaty, Russia
Release form: tablets, ointment, cream, lyophilisate for the preparation of infusion solution

Active ingredient: Acyclovir

Synonyms: Zovirax, Gerpevir, Virolex, Vivorax

The analog Acyclovir has an immunomodulatory effect and is also used for herpes infections, herpes zoster, and chickenpox. Applied topically and consumed in tablets.

Reviews and prices

The drug has mixed reviews. Not all studies confirm the effectiveness of the active substance. The product is used only in domestic practice. A clear advantage of Arbidol can be considered good tolerability. According to doctors, the effects of treatment occur only when the pills are taken in a timely manner.

The average price of a package of children's medicine for 40 tablets (100 mg) is 750 rubles. The average price of a package of an adult drug for 10 tablets (200 mg) is 500 rubles.

Reviews

Svetlana, 56 years old: I got a cold, and after my temperature rose, I called a doctor to my house. She listened to me and prescribed Paracetamol and Arbidol. I took pills for a whole week and didn’t notice any improvements, although Arbidol used to help with colds. Vyacheslav, 62 years old: When a cough appeared and the temperature rose, I thought that I had caught a new coronavirus. I read a lot on the Internet about Arbidol, that it helps, so I called a doctor to my house and asked her if maybe I should drink it. I was surprised when the doctor began to dissuade me and prescribed only cough and fever pills. She explained to me that Arbidol does not act on all types of viruses, so there is no chance that it will help. Marina, 48 years old: This is the third day I’ve been taking Arbidol for ARVI, it seems to be getting better, although the temperature still persists, but the cough seems to have become slightly worse. a bit less. The doctor says I need to continue taking the pills and get tested.

Contraindications

Not all patients tolerate the medication well. Any components of the tablet, powder or capsule can cause an allergic reaction. This condition is manifested by a skin rash, redness of the integumentary tissue, dizziness and other pathological signs. If signs of an allergy appear during treatment, you must stop taking the pills and consult a doctor.

Arbidol eliminates the symptoms of ARVI

• Children under two years of age.
• Carrying a child.
• Breast-feeding.
• Severe dysfunction of the kidneys and liver.

Important! You should consult your doctor before starting treatment. Individual contraindications are possible.

conclusions

Ingavirin and Arbidol belong to the same antiviral group of drugs. Their pharmacological properties are identical, but the mechanisms of action on viruses differ. Arbidol has a direct effect on those viruses that have entered the human body and cause certain diseases. Its effectiveness has been proven by a large number of clinical studies conducted on animals, children and adults over a long period of time. It can be used by children under 2 years of age as prescribed by a doctor. Ingavirin influences to a greater extent not the viruses themselves, but directly the human immune system. This medicine belongs to a new generation. Its effect on the disease, the immune system and the human body as a whole is poorly understood, especially in the long term. In fact, Ingavirin is an immunomodulator.

Regardless of what viral disease a person develops, it is imperative to consult a doctor and take all medications strictly as prescribed.

Sources

• https://med-post.ru/zdorove/pomogaet-arbidol-koronavirusa
• https://endokrinolog.online/arbidol-ot-koronavirusa/
• https://arbidol.ru/instruktsiya-arbidol-capsules-100.html
• https://expertology.ru/sravnivaem-arbidol-i-ingavirin-opredelyaem-luchshiy/
• https://www.medcentre24.ru/medicamenty/arbidol.html
• https://medside.ru/arbidol
• https://netbolezni.net/infektsionnyye-bolezni/1072-arbidol-ot-koronavirusa-pravda-ili-net.html
• https://zabolevshie-coronavirusom.ru/arbidol-ot-koronavirusa
• https://aptstore.ru/articles/arbidol-instruktsiya-mozhno-li-detyam-i-beremennym/
• https://LekAnalog.ru/arbidol-analogi-deshevle/

Does it help with fever?

Arbidol is an antiviral drug; it stops the growth and development of viruses, but this medication does not have an antipyretic property.
That is, it is impossible to reduce the temperature with Arbidol. Fever is one of the first symptoms that occurs during an infectious disease. When pathogens enter the mucous membranes, the process of phagocytosis begins. The blood produces cells that fight foreign organisms. As a result, the temperature rises by 1-3 degrees.

When you have a fever, it is necessary to drink Arbidol, because it indicates the presence of an inflammatory process, which in 99% of cases is caused by viruses. To determine the type of pathogenic microorganisms, you need to consult a doctor and get tested. If bacteria become the causative agent of the disease, then there is no point in taking Arbidol. In this case, the doctor prescribes broad-spectrum antibacterial drugs.

How to replace Arbidol

If there are any contraindications for the use of Arbidol, then it can be replaced with a drug of similar effect.

The most common and frequently used drugs are:

• Amizon can be used by children and adults during an epidemic. Quickly and effectively destroys viruses.
• Amexin effectively fights viruses at the initial stage of the disease. reduces symptoms.
• Viferon destroys different types of pathogens. It can be used by women during pregnancy and breastfeeding. The drug is used for the prevention and treatment of influenza and ARVI.

As a result, it can be determined whether Arbidol reduces the temperature. We can definitely say that it does not have antipyretic properties, like, for example, Paracetamol. But the drug affects viral cells and blocks their development. By reducing the concentration of pathogenic microorganisms, the intensity of the inflammatory process decreases and, as a result, body temperature decreases.

How to use

The dosage is prescribed by a specialist, based on the symptoms and individual characteristics of the patient’s body. For prevention, you can take tablets or capsules 2-3 times a week. In case of illness, an integrated approach is required, where Arbidol will act as an antiviral drug. In addition, to lower the temperature, you need an antipyretic, nasal drops, cough tablets, etc., depending on the symptoms.

It should be taken at the initial stage of the disease 3-4 times a day. The tablet or capsule is washed down with plenty of clean water (not juice, milk, tea, but water). The course of treatment is on average 5-10 days. To activate the immune system during an epidemic, take 1

tablet 3 times a week for three weeks.