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AZELIC is a drug for the treatment of acne and rosacea. Belongs to the group of drugs for the treatment of acne - other drugs for the treatment of acne for external use (D10AX03). Active ingredient: Azelaic acid.
The drug AZELIQ has an antioxidant and antiandrogenic effect. Reduces oiliness, cleanses pores, inhibits bacterial growth, reduces inflammation. Dispensed without a doctor's prescription!
Composition and release form
The drug Azelik is available only in the form of a gel for external use ; pharmacies offer options in volumes from 5 to 30 grams. The main active substance that provides the therapeutic effect is azelaic acid.
The composition also contains auxiliary components, including:
- Macrogol;
- Carbomers;
- Squalane;
- Purified water;
- Bezoic acid;
- Propylene glycol;
- Methylpyrrolidone;
- Sodium in the form of hydroxide.
Azelaic acid is quickly absorbed and penetrates into the deep layers of the epidermis.
No more than 3.6% of the used dose of the drug penetrates into the systemic circulation. Excretion is carried out by the kidneys - partly in unchanged form, partly in the form of oxidized metabolites, which are dicarboxylic acids.
Which is better: AZELIQ or Skinoren
AZELIK and Skinoren.
Photo: generic-forum.ru Both drugs are analogues of each other. Active ingredient: Azelaic acid. The content of the active component is different: AZELIQ contains 150 mg, and Skinoren contains 150 mg (for gel) and 200 mg (for cream). Both drugs are indicated for the treatment of acne and rosacea, but an additional indication for Skinoren cream is hyperpigmentation (eg, chloasma, melasma). Allowed in pediatrics from 12 years of age. Dispensed without a doctor's prescription!
The country of origin of the drug AZELIQ is Russia. Skinoren is produced in Italy. Skinoren is more expensive than AZELIQ. Price per package from 530 rub.
Indications for use
The main indications for the use of Azelik are the following diseases:
- Rosacea is a chronic disease, the drug is used to suppress the main symptoms and minimize the risk of relapses and exacerbations;
- The appearance of a large number of pimples on the face and other parts of the body;
- Excessive activity of the sebaceous glands , leading to clogged pores and skin irritations.
Beneficial features
The main positive effect of using Azelik gel is the elimination of signs of acne and excessive pigmentation.
The drug also has a number of other useful properties, thanks to which similar results are possible:
- Detrimental effect on bacterial microflora , causing skin irritations;
- Normalizing the functioning of the sebaceous glands and reducing the volume of fatty acids produced;
- Prevention of blockage of hair follicles and subsequent development of inflammatory processes;
- Suppression of the activity of pigment cells with abnormal development;
- Impact and normalization of the processes of keratinization of the epidermis at the cellular level;
- Prevention of benign types of skin pigmentation, which belong to the group of aesthetic defects.
It is worth noting that Azelik affects inflammatory processes precisely in the final stages, when free fluid accumulates in their foci.
This helps prevent the appearance of purulent lesions in their place, which are often accompanied by a secondary infection.
Tips from Azelik gel manufacturers
- It is not recommended to use additional products containing acids - this can lead to skin burns.
- The skin must be moisturized with creams, thermal water or nourishing gels for washing.
- In the summer, sunscreen must be applied on top of the Azelik gel to avoid getting burned.
- The main thing in the fight against acne is hygiene (a separate face towel and clean hands).
- You should not squeeze pimples during treatment, as thinned skin takes a long time to heal.
As they say, reviews on Azelik gel are the most popular and effective drug that is used to treat acne and acne.
Most patients say that the effect of the drug becomes noticeable 21 days after starting use. During this period, the facial skin is noticeably cleansed, inflammation and external manifestations of the disease are reduced.
How to use it correctly?
External use of Azelik is the only acceptable way to use the gel; application is carried out on the affected skin in the absence of contraindications.
Avoid getting any amount into the digestive system and mucous membranes, as this will provoke unwanted reactions from the body.
The use of Aezlik gel is carried out in accordance with the instructions given below:
- Application should only be carried out on clean skin , so you should wash your face first; you can use light cosmetics with a cleansing effect;
- After hygiene procedures, the face must be thoroughly wiped with a towel , since application of the drug is allowed only on dry skin;
- Application is carried out locally on the affected areas of the skin , the amount of gel depends on the area of the lesions: the drug should be applied in uniform thin layers;
- Azelik is applied 2 times a day in the morning and evening;
- When applying the gel, it must be rubbed into the skin with light massaging movements of the fingers, this will improve its absorption and penetration of the active substance deep into the tissues;
- To treat the entire surface of the face, it is enough to squeeze out a strip of gel about 2.5 cm long;
- The positive effect becomes noticeable a month after the start of treatment, but to consolidate the achieved result, the duration of the course should be at least 2-3 months;
- If there is no positive result within a month or the need to take a longer course, you must consult with the doctor who prescribed the use of Azelik gel;
- If side effects occur in the form of increased local irritation, the frequency of use is reduced to 1 time per day. After the body adapts and the unwanted reactions disappear, you should return to the standard treatment regimen using the drug in the morning and evening hours.
Throughout the entire course of treatment using Azelik gel, you should minimize the time spent in direct sunlight.
Use during pregnancy and lactation
Pregnancy is not a direct contraindication for the use of Azelik gel, but this product must be used with extreme caution.
You should first consult with a specialist and obtain appropriate permission from him.
The drug is prescribed only in case of urgent need. The same precautions should be taken during breastfeeding.
Which is better: AZELIK or KLENZIT-S
KLENSIT-S.
Photo: aptekamskgos.ru The drugs are not analogues of each other. Active ingredient of the drug AZELIQ: Azelaic acid. KLENSIT-S is a combination drug with the active ingredients Adapalene and Clindamycin. Both drugs are indicated for acne. Release form: gel for external use. The drug AZELIQ is applied 2 times a day; KLENSIT-S gel is used once a day. Approved for use from 12 years of age.
The drug AZELIQ is produced in Russia. KLENSIT-S is produced in India. In terms of cost, KLENSIT-S is more expensive than AZELIK.
Side effects
Undesirable and side effects in response to the use of Azelik occur only in rare cases; they are associated with a reaction from the subcutaneous fatty tissue and epidermis.
Possible manifestations include:
- Peeling , dryness and feeling of tightness of the skin;
- Local redness as a result of a rush of blood to the vessels and an increase in the temperature of the epidermis;
- Physical discomfort due to itching and burning at the site of application of the gel;
- Skin allergic reactions.
Such side effects in mild form are considered a normal reaction and do not require discontinuation of the drug. They go away on their own during treatment.
Price
Azelik is freely available and can be purchased without presenting a prescription written by your doctor. The cost of the drug depends on the volume of the tube.
Approximate current prices are given below:
- A tube containing 5 grams of Azelik gel costs 300 rubles ;
- A tube containing 15 grams gel costs 450 rubles ;
- A tube containing 30 grams of Azelik gel costs 660 rubles .
Possible analogues
The drug Azelik has analogues, the use of which can provide the same therapeutic effect and result.
Some options for products with similar effects are discussed below:
- Azix-Derm is an Indian-made cream; it is the main analogue of Azelik gel, since it also contains azelaic acid. The indications and features of use are the same; the cost of a 30 gram tube is about 650 rubles ;
- Skinoclear is another product for topical use, available in the form of a 15% gel or 20% cream. The main active substance is also azelaic acid, the drug is produced in the Russian Federation. The cost of a tube containing 30 grams of product ranges from 500 rubles ;
- Skinoren is an Italian analogue based on azelaic acid, available in pharmacies as a 15% gel or 20% cream. Depending on the volume of packaging, the cost can vary from 750 to 1700 rubles ;
- Metrogyl - produced in the form of a gel, has antibacterial activity and affects anaerobic microorganisms; when applied topically, it can reduce the number of acne and reduce inflammation. The composition contains metronidazole, its concentration in the drug does not exceed 10 mg. The product can be purchased at a price of 200 rubles ;
- Roaccutane is not available in the form of topical preparations; the only form of release is capsules for oral administration containing isotretinoin. The use of Roaccutane is possible only upon receipt of a prescription from the attending physician. The cost of a package containing 30 capsules is 3,000 rubles ;
- Zinerit - available in the form of an anti-acne lotion for external use, it contains zinc acetate and erythromycin. The drug has a complex effect, eliminating pathogenic bacterial microflora, normalizing the functioning of the sebaceous glands and reducing inflammation. To completely get rid of skin rashes, you need to complete a course lasting 2-2.5 months. You can purchase a bottle containing 30 ml of the drug for a price of 500 rubles .
Azix-Derm
Skinclear
Skinoren
Metrogil
Roaccutane
Zenerite
pharmachologic effect
The clinical activity of Azelik gel 15% is based on the properties of the active substance - azelaic acid. The organic compound is characterized by keratolytic, antibacterial, anti-inflammatory therapeutic efficacy.
Azelaic acid inhibits pathogenic gram-positive propionibacteria acnes, staphylococci, streptococci. After its penetration into the epidermis, the production of proteins necessary for the construction of microbial membranes is blocked. At the same time, the synthesis of bacterial RNA and DNA is disrupted, which leads to the death of pathogenic microorganisms.
Azelaic acid also has the following pharmacological actions:
- anti-inflammatory. The Azelik gel ingredient inhibits the enzyme oxidoreductase, reducing the production of free radicals. The inflammatory process slows down due to the cessation of destruction and oxidation of dermal cells;
- keratolytic. Azelaic acid regulates keratin formation, reducing the synthesis of cellular proteins. As a result of slowing down the division of keratinocytes, the processes of comedones formation are stopped;
- brightening. The organic compound blocks the enzyme tyrosinase, inhibiting the growth of abnormal melanocytes and reducing their activity. The more azelaic acid contained in Azelik, the higher its lightening properties.
Suppressing inflammation and destroying bacteria helps normalize blood circulation in damaged tissues. Their cells are saturated with nutrients, microelements, fat- and water-soluble vitamins. Metabolism in tissues is significantly accelerated, and, consequently, regeneration.
Release form and composition
Azelik is produced at the Russian pharmaceutical factory Akrikhin. It is available in 5 and 30 g packaging, packaged in aluminum tubes with a screw cap. Each is enclosed in a cardboard box along with instructions for use. The active ingredient of the gel is azelaic acid.
The auxiliary composition of Azelik is represented by the following components:
- benzoic acid;
- methylpyrrolidone;
- propylene glycol;
- disodium edetate;
- squalane;
- sodium hydroxide;
- dimethicone;
- carbomer inerpolymer;
- macrogol;
- cetostearate
- purified water.
One of the important additional ingredients of Azelik is squalane. This hydrocarbon is found in many medicinal and cosmetic products. It accelerates the regeneration of damaged cells and protects them from destruction by free radicals.
Thanks to the presence of squalane, Azelik has a pronounced moisturizing effect. The hydrocarbon also stimulates local immunity and has antiseptic activity.
Storage conditions and periods
Azelik should be stored in a place protected from sunlight at room temperature. If these conditions are not met, the gel delaminates, changes color, smell, and becomes unsuitable for treatment.
The drug should not be frozen. At low temperatures, its physicochemical properties change. Shelf life is 24 months, after opening the primary packaging it is limited to 3-4 weeks.
Reviews
Reviews about the use of Azelik gel:
Which is better: AZELIK or Azix-Derm
Cream Azix-Derm 20%.
Photo: eapteka.ru The drugs are analogues of each other. AZELIQ is produced in the form of a gel for external use. Release form of the drug Azix-Derm: cream for external use. The concentration of the active substance is higher in Azix-Derma - 200 mg; AZELIQ contains 150 mg. They differ in the composition of auxiliary components. Approved for use in children over 12 years of age.
The country of origin of AZELIK gel is Russia. Azix-Derm is produced in India. Azix-Derm is more expensive than AZELIK.
