From this article you will learn:
- indications for use in acne and pimples,
- instructions for use,
- reviews of drugs from the Klenzit line.
Klenzit and Klenzit-S are a line of medications for external use (in the form of gels) that are intended for the treatment of acne and pimples. The main active component of these drugs is the retinoid adapalene 0.1%, which significantly reduces the hyperactivity of the sebaceous glands, normalizes the phenomena of follicular hyperkeratosis, and also has an anti-inflammatory effect.
But if the Klenzit gel contains only adapalene, then Klenzit-S, in addition to adapalene, also contains the antibiotic clindamycin 1%. The latter has antimicrobial activity against the bacteria Propionibacterium acnes (P.acnes) and Staphylococcus epidermidis (S.epidermidis), which play an important role in the formation of acne and pimples, such as comedones, papules or pustules.
Preparations Klenzit-S and Klenzit: photos
The drugs are produced by Indian pharmaceutical companies and are sold in pharmacies without a prescription. Age restrictions exist only for the Klenzit-S gel, which is recommended for use only in persons over 12 years of age. In this article, we will tell you about international protocols for the treatment of acne (acne and pimples), and you will be able to understand which of these drugs should be used specifically in your case, as well as for how long.
How much do the Klenzit line drugs cost in pharmacies:
The drugs are available in tubes of 15 and 30 g, but due to the fact that the treatment is long-term, it is irrational to buy small packages. For Klenzit gel, the price will be from 700 rubles (for a tube of 30 g), and it is cheaper than drugs with 0.1% adapalene - in pharmacies with the same composition you can only find “Adaklin” for 550 rubles. But the latter is available only in the form of a cream, while gel forms of topical retinoids are more effective (with equal concentrations of adapalene).
Another similar drug, Differin, will cost from 800 rubles (30 g tube). As for the drug Klenzit-S, the price for it will be from 870 rubles. But we immediately want to warn you that incorrect prescription and use of the drug Klenzit-S can play a cruel joke and lead to the formation of antibiotic resistance in P.acnes bacteria. And in turn, this will certainly lead to a worsening of the disease in the long term.
Instructions for use of CLENSIT
Active substance | Adapalene |
pharmachologic effect | Anti-inflammatory; Comedolytic |
Vacation conditions | Over-the-counter |
Release form | Gel for external use |
Pregnancy and breastfeeding | Not recommended |
Age group | 12+ |
Best before date | 3 years |
Storage conditions | Not higher than +25 °C |
Analogs |
|
Category | Dermatological preparations |
Instructions for use (PDF) | Gel KLENSIT |
Manufacturer | GLENMARK (India) |
Price | from 402 rub. |
Mode of application
Externally. Before using KLENSIT gel, you must clean and dry your facial skin. With a light touch, apply the gel evenly to the affected surface once a day before bedtime on clean, dry skin, avoiding contact of the drug with the eyes and lips.
The therapeutic effect develops after 4-8 weeks of treatment with KLENSIT, persistent improvement after 3 months of treatment. In some cases, due to short-term skin irritation, treatment may be suspended until signs of irritation disappear. A repeated course of treatment is possible after consultation with a doctor.
Compound
Gel KLENSIT
- active ingredient: Adapalene 1 mg per 1 g;
- excipients: disodium edetate, carbomer 940 (carbopol 940), propylene glycol, methyl parahydroxybenzoate, phenoxyethanol, poloxamer 407, sodium hydroxide, purified water.
The structural formula of Adapalene is C28H28O3. Photo: rlsnet.ru
Indications for use
Acne.
Contraindications
- pregnancy;
- lactation period (breastfeeding);
- hypersensitivity to one of the ingredients of the drug.
Side effects
Dermatological reactions: skin irritation (treatment should be suspended until the skin irritation disappears or the frequency of use should be reduced).
pharmachologic effect
Adapalene (active ingredient of KLENSIT gel) is a retinoid metabolite, has comedolytic and anti-inflammatory effects, normalizes the processes of keratinization and epidermal differentiation.
The mechanism of action of adapalene is based on interaction with specific γ-receptors of epidermal skin cells. As a result of the action of adapalene, in particular, there is a decrease in the “adhesion” of epithelial cells at the mouth of the pilosebaceous follicle and a decrease in the prerequisites for the formation of microcomedones.
Adapalene has an anti-inflammatory effect in vitro and in vivo, affecting inflammatory factors by inhibiting the migration of leukocytes at the site of inflammation and the metabolism of arachidonic acid.
Precautionary measures
With caution: dermatitis, eczema.
CLENSIT during pregnancy
It is not recommended to use the drug during pregnancy and lactation (breastfeeding).
special instructions
- Avoid getting the gel in your eyes and lips. In case of accidental contact of the drug with the mucous membranes of the eyes, mouth or nose, rinse them thoroughly with warm water.
- Avoid direct sunlight, as... Skin irritation may occur. Treatment can be continued if sun exposure is kept to a minimum (use of sunglasses and hats).
- The simultaneous use of cosmetics with a drying and irritating effect on the skin (for example, perfumes or alcohol-containing products) is not recommended.
- Adapalene applied to the skin in the evening can be combined with acne medications used in the morning.
Contraindications
An absolute contraindication to the use of the gel is individual intolerance to one of the components. The manufacturer did not provide data on the absence of teratogenic effects. Therefore, the use of Klenzit S during pregnancy and breastfeeding is strictly prohibited. It is also not intended for the treatment of acne in children under 12 years of age.
The drug should be used with caution in the presence of the following pathologies:
- allergic diseases, in remission and during exacerbations;
- dry and weeping eczema;
- dermatitis.
It is recommended to discontinue therapy if muscle relaxants are currently used. This is the name of drugs for relieving muscle spasms characteristic of diseases of the musculoskeletal system.
KLENSIT gel cleanser
KLENSIT skincare gel for washing.
Photo: goodslike.ru The drug KLENSIT is not used in the form of a gel for washing. For these purposes, the manufacturer has released the cosmetic product KLENSIT skincare gel for washing, which contains Salicylic acid, Aloe vera, Zinc and Allantoin.
Which is better: KLENSIT or KLENSIT-S
KLENSIT-S.
Photo: aptekamskgos.ru The drugs are not analogues of each other. KLENSIT is a one-component drug with the active substance Adapalene, aimed at combating blackheads. Gel KLENSIT-S is a two-component preparation. Active ingredients: Adapalene and Clindamycin. Indicated for the treatment of inflamed acne: papules and pustules. Accordingly, it is aimed at more serious dermatological diseases. Both are approved for use from 12 years of age. Dispensed without a doctor's prescription!
Both drugs are produced in India. The cost of KLENSIT-S is more expensive than KLENSIT. Price per package from 453 rub.
Expert opinion
Lyudmila Sheveleva
Higher pharmaceutical education, pharmacist. Work experience in a pharmacy - more than 20 years.
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Clenzit gel is one of the best remedies for acne treatment. It copes with both small pimples and large blackheads. Its effectiveness has also been proven in eliminating blackheads, which often form on the wings of the nose. The drug does not just relieve the external manifestations of acne. Its action is aimed at eliminating its cause - excessive secretion of sebaceous secretions. Therefore, after the end of the therapeutic course, the formation of new rashes is not observed for quite a long time.
Which is better: CLENSIT or AZELIK
Gel AZELIQ.
Photo: uteka.ru Both drugs are not analogues of each other. KLENSIT is indicated for the treatment of acne. Active ingredient: Adapalene (is a synthetic analogue of retinoic acid). Release form: gel for external use. The drug AZELIK contains Azelaic acid, a dibasic saturated carboxylic acid. It has bacteriostatic activity, has anti-acne and depigmenting effects. Apply the drug 2 times a day (morning and evening). Indications of the drug:
- mild to moderate acne, incl. in the presence of papules and pustules;
- rosacea, incl. in the presence of papules and pustules.
Both are approved for use from 12 years of age (for the treatment of rosacea, AZELIQ is indicated from 18 years of age).
The country of origin of CLENSIT is India. The drug AZELIK gel is produced in Russia. AZELIK is cheaper in cost than CLENSIT.
Which is better: CLENSIT or DIFFERIN
DIFFERIN.
Photo: galderma.com The drugs are analogues of each other. Active ingredient: Adapalene. KLENSIT is produced in the form of a gel for external use; The drug DIFFERIN is produced in the form of a cream (best indicated for dry and fair skin) and gel (for oily skin). Both drugs are indicated against acne. Allowed from 12 years of age. Dispensed without a doctor's prescription!
The country of origin of CLENSIT is India. DIFFERIN is produced in France. DIFFERIN is more expensive than CLENSIT.
Which is better: KLENSIT or BAZIRON AS
BAZIRON AS 5%.
Photo: otzovy.ru The drugs are not analogues of each other. Active ingredient of KLENSIT: Adapalene. Release form: gel for external use. The drug BAZIRON AS is produced in the form of a gel in concentrations of 2.5%, 5% and 10%. Active ingredient: Benzoyl peroxide (has a strong antimicrobial effect). Indicated in the treatment of acne. Due to the different concentrations of the active substance in the drug BAZIRON AS, it can be prescribed for different degrees of severity of the disease. Both drugs are approved from 12 years of age. Dispensed without a doctor's prescription!
The country of origin of CLENSIT gel is India. The drug BAZIRON AS is produced in France. In terms of cost, BAZIRON AS is more expensive than KLENSIT.
Which is better: CLENSIT or Effezel
Gel Effezel.
Photo: afrodita.guru Both drugs are not analogues of each other. Active ingredient of KLENSIT: Adapalene. Release form: gel for external use. The drug Effezel is a two-component product with the active substances Adapalene and Benzoyl peroxide. Available in the form of a gel for external use. Both drugs are indicated in the treatment of acne, but Effezel has additional indications for inflamed acne. The frequency of use of the drugs is the same - 1 time per day. Approved in pediatrics: KLENSIT from 12 years; Effezel since he was 9 years old. KLENSIT gel is available over-the-counter, and Effezel is available with a doctor's prescription!
The country of origin of CLENSIT is India. Effezel is produced in France. In terms of cost, Effezel is more expensive than CLENSIT.
Indications for use
A drug with a powerful therapeutic effect is recommended by specialists in cases where a severe clinical picture is observed.
For acne
It is disruptions in the natural functioning of the secretory glands of the skin that lead to the formation of hated inflammations. Clenzit C restores the function of the sebaceous glands and prevents the production of excessive sebum. The drying effect of the gel helps reduce inflamed elements. As a result, the skin is cleared of old rashes, and the drug also blocks the development of new foci of the disease.
For acne
The main culprits of acne are bacteria of the coccal flora, which are activated under the influence of external and internal factors. As a rule, an excess of sebaceous secretion occurs due to hormonal imbalance, especially against the background of increased testosterone levels.
The broad-spectrum antibiotic included in the ointment stops the proliferation of pathogenic microorganisms of coccal etiology, thereby demonstrating a positive therapeutic effect.
For subcutaneous acne
Unlike regular acne, subcutaneous acne develops in the deeper layers of the epidermis and is characterized by very unpleasant pain. Klenzit C penetrates into the skin, thanks to which it affects even deep elements of an inflammatory nature.
In addition, the gel relieves swelling of the affected areas of the skin, and the analgesic effect of the antibiotic helps reduce pain.
For post-acne
Preventing the development of acne is not as difficult as getting rid of the scars and red spots left after the disease. In this case, a retinoid-based drug acts most effectively. Vitamin A promotes active cell division, due to which pronounced regeneration of the skin occurs. With proper use, post-acne elimination and overall smoothing of the skin texture are observed.
Which is better: KLENSIT or Skinoren
Skinoren gel.
Photo: skinoren.ru The drugs are not analogues of each other. The active component of CLENSIT is Adapalene. Release form: gel for external use. The drug Skinoren contains Azelaic acid. Available in the form of 15% gel and 20% cream for external use. Both are indicated for the treatment of acne. Skinoren cream is additionally prescribed for hyperpigmentation. Allowed from 12 years of age. KLENSIT is applied once a day (evening), and Skinoren is used in the morning and evening. Dispensed without a doctor's prescription!
The country of origin of CLENSIT is India. Skinoren is produced in Italy. In terms of cost, Skinoren is more expensive than CLENSIT.
conclusions
- Klenzit S was developed by the leading company Glenmark, which occupies a leading position in the global pharmaceutical market.
- A specially developed combination of vitamin A and antibiotic copes with the most severe forms of acne.
- For best results, it is recommended to use the product before bed, applying a thin layer of gel with careful strokes without further rubbing.
- If you use the product in the warm season, do not forget to additionally protect the treated areas with a high spf cream. This precaution will help avoid the formation of freckles and age spots.