Instructions for use of Bisacodyl (Method and dosage)
For those who take Bisacodyl tablets, the instructions for use indicate that this should be done orally in the evening before bed. The starting dose for adults is 5 mg. If the desired effect is not achieved, the dosage can be increased to 15 mg. The instructions for Bisacodyl for children over 6 years old set the dose at 5 mg.
Before surgical operations and medical examinations, take 10 mg of the drug at night.
If Bisacodyl suppositories are used, the instructions for use indicate that this product should be used in dosages of 10-20 mg. For children over 8 years old, 10 mg should be used. And for children from 2 to 7 years old, the drug is recommended to be used at a dose of 5 mg.
The laxative Bisacodyl Acre is taken orally at bedtime or half an hour before breakfast. For adults and children, dosages of 5-15 mg are indicated. Children from 8 to 14 years old are given 5-10 mg. And for children from 2 to 7 years old – 5 mg. The product must be swallowed whole, you can take it with some liquid, but do not chew it.
Before surgical operations, as well as medical research, take 2 tablets per day in the evening.
Instructions for use of Bisacodyl Hemofarm provide the same dosage and administration regimen.
Interaction
Combination with antacid drugs, Ranitidine , Cimetidine , Omeprazole reduces the laxative effect and provokes irritation of the gastric mucosa, which is accompanied by severe pain .
Opiates , cholestyramine , psychotropic and anticholinergic drugs also reduce the effect of the drug.
A long course of Bisacodyl together with cardiac glycosides enhances the effect of the latter.
Carbenoxolone , Hydrochlorothiazide , Prednisolone , Methylprednisolone , Furosemide , Hydrocortisone and Dexamethasone in combination with Bisacodyl increase potassium loss in the body. Accordingly, a deficiency of this microelement may develop.
Pharmacological properties
Pharmacodynamics
Bisacodyl is a diphenylmethane derivative. It has a laxative effect by increasing the secretion of mucus in the large intestine, as well as accelerating and enhancing its peristalsis. This effect is due to direct stimulation of nerve endings located in the mucous membrane of the colon.
Pharmacokinetics
The drug is not absorbed from the gastrointestinal tract. Bisacodyl is a prodrug, from which, during hydrolysis in an alkaline environment, a substance is formed that has an irritating effect on the mucous membrane of the large intestine.
Bisacodyl for weight loss
Some people use Bisacodyl for weight loss. However, it should be borne in mind that such a remedy will not help get rid of fat deposits. It only helps to remove toxins and waste from the body, as well as improve intestinal function. To some extent, weight is reduced, but this drug is by no means intended for weight loss.
Before you start using Bisacodyl, you need to have a good understanding of what it is and how it should be used. Otherwise, there is a risk that addiction may develop, as well as various side effects (intestinal atony, etc.).
During pregnancy (and lactation)
This drug is almost not absorbed into the bloodstream. It does not have a toxic effect on the fetus and does not contribute to the contractile activity of the uterus. Thus, the drug can be taken during pregnancy . For example, in case of constipation or the need to prepare the body for medical procedures.
However, during pregnancy this remedy should be used with caution. It stimulates active peristaltic movements of the intestines, which may be slightly painful. You need to prepare for such effects.
The drug is harmless to both the woman and the fetus, but it should not be abused. It should be used only if indicated and if other, more natural remedies do not have the desired effect.
It is advisable for pregnant women to use the medicine in the form of suppositories to minimize passage through the gastrointestinal tract. Suppositories and tablets should be used in normal dosages for adults. You need to start using the initial dose (1 suppository or tablet). If necessary, it can be increased the next day.
Contraindications
Absolute contraindications for the use of laxatives are:
- Children under 2 years of age.
- Allergic reaction to active or auxiliary components.
- Violation of the integrity of the anus.
- Severe gastrointestinal diseases.
- Inflammation of the anterior abdominal wall.
- Hernia.
- Spastic constipation.
- Intestinal neoplasms.
- Pain in the epigastric region of unknown etiology.
- Inflammatory lesion of the caecum.
- Gynecological bleeding.
- Cystitis.
- Dehydration of the body.
- Violation of water balance.
- Blood loss from the gastrointestinal tract.
It is also not recommended to use the drug during pregnancy, lactation, liver and kidney diseases.
Reviews about Bisacodyl
Reviews of Bisacodyl may vary depending on the dosage form that is used.
Opinions about suppositories are usually positive. Reviews of Bisacodyl suppositories report the rapid action of this product. Those who have used them note that the laxative effect occurs within about 10-15 minutes after use. Even one suppository, as a rule, causes active bowel movements.
Reviews of Bisacodyl tablets also report that the laxative effect occurs quickly. But they must be taken with caution. Those who have used them recommend starting with a minimum dose, since the drug is potent.
There are also negative reviews about the tablets. People report severe side effects.
Bisacodyl for weight loss receives very different reviews. Those who used it with caution noted that the product helped with short-term weight loss before the holidays. On average, they get rid of about 2-3 kg. In this case, people took 1-2 tablets every other day for a short time (no more than 2 times in 7 days).
However, you can often find stories about negative consequences. In this case, people tended to use the laxative uncontrollably and as a result, it had a negative impact on their health. Such reviews are usually left by girls who, along with a diet, took the drug every day, trying to empty their intestines as much as possible. As a result, the body loses not only toxins, but also a lot of useful substances, dysbiosis develops, an imbalance of electrolytes, dehydration, and intestinal atony . of peristalsis becomes necessary for emptying . Moreover, the dosage of the drug has to be increased. So people who use it incorrectly report developing a kind of addiction. It's not easy to get rid of it. So reviews of Bisacodyl as a means of losing weight are very often negative.
Side effects
Most often, side effects occur with frequent use of the drug.
The following symptoms may occur:
- colic;
- diarrhea (in case of overdose);
- disturbances of electrolyte metabolism;
- muscle weakness or cramps due to excessive potassium excretion;
- hypotension;
- stomach pain (in case of overdose);
- dizziness, fainting;
- addiction.
To restore electrolyte metabolism, it is recommended to take drugs such as Regidron, Humana. This will reduce the likelihood of side effects and neutralize the negative effects of Bisacodyl.
Contraindications
Bisacodyl should not be used for:
- liver failure;
- intestinal obstruction or hernia;
- acute diseases of the abdominal cavity, including appendicitis, peritonitis, gastrointestinal bleeding;
- hemorrhoids;
- renal failure;
- increased individual sensitivity.
It is not recommended to prescribe Bisacodyl for long-term use ; it is better to choose laxatives with another active ingredient. Symptomatic treatment with Bisacodyl should last no longer than 7 days. With prolonged use, addiction occurs, as a result of which subsequent acts of defecation will be possible only while taking the drug.
Intestinal atony that occurs as a result of such addiction is practically untreatable, so this condition should not be tolerated.
Patients with diabetes should take the drug with caution.
Use during pregnancy
There is no sufficient data regarding the clinical effects of taking Bisacodyl in pregnant women. Bisacodyl is known to pass into breast milk. Pregnant and lactating women are better off taking lactulose-based medications for constipation.
Bisacodyl price, where to buy
How much this drug costs depends on the form of release and the manufacturer. The price for Bisacodyl laxative suppositories is, as a rule, slightly higher than 20 rubles per pack of 10 pieces. The cost of 5 mg tablets (20 pieces per package) from the Latvian company Grindeks is about 40 rubles. And the price of Bisacodyl 5 mg tablets, 30 pieces per package from the Russian manufacturer Ozon LLC, is about 15 rubles.
In turn, the price of Bisacodyl in Ukraine is as follows:
- candles for constipation - about 6 hryvnia;
- tablets – 10-14 hryvnia.
This cost is considered very affordable among analogues.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
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Pharmacy Dialogue
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Pharmacy24
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PaniPharmacy
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