Dolac
Often - more than 3%, less often - 1-3%, rarely - less than 1%.
From the digestive system
: often - gastralgia, diarrhea; less often - stomatitis, flatulence, constipation, vomiting, feeling of fullness in the stomach; rarely - loss of appetite, nausea, erosive and ulcerative lesions of the gastrointestinal tract (including with perforation and/or bleeding - abdominal pain, spasm or burning in the epigastric region, blood in the stool or melena, vomiting with blood or “coffee grounds” type, nausea, heartburn, etc.), cholestatic jaundice, hepatitis, hepatomegaly, acute pancreatitis.
From the urinary system
: rarely - acute renal failure, lower back pain, hematuria, azotemia, hemolytic-uremic syndrome (hemolytic anemia, renal failure, thrombocytopenia, purpura), increased urination, increased or decreased urine volume, nephritis, edema of renal origin.
From the senses
: rarely - hearing loss, ringing in the ears, visual impairment (including blurred vision).
From the respiratory system
: rarely - bronchospasm or dyspnea, rhinitis, pulmonary edema, laryngeal edema (shortness of breath, difficulty breathing).
From the central nervous system
: often - headache, dizziness, drowsiness; rarely - aseptic meningitis (fever, severe headache, convulsions, stiffness of the neck and/or back muscles), hyperactivity (mood changes, anxiety), hallucinations, depression, psychosis, fainting.
From the cardiovascular system
: less often - increased blood pressure.
From the hematopoietic organs:
rarely - anemia, eosinophilia, leukopenia.
From the hemostasis system
: rarely - bleeding from a postoperative wound, nosebleeds, rectal bleeding.
From the skin
: less often - skin rash (including maculopapular rash), purpura; rarely - exfoliative dermatitis (fever with or without chills, hyperemia, thickening or peeling of the skin, swelling and/or tenderness of the tonsils), urticaria, malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome).
Local reactions
Less common: burning or pain at the injection site.
Allergic reactions
: rarely - anaphylaxis or anaphylactoid reactions (change in facial skin color, skin rash, urticaria, skin itching, tachypnea or dyspnea, swelling of the eyelids, periorbital edema, shortness of breath, difficulty breathing, heaviness in the chest, wheezing).
Others
: often - swelling (face, legs, ankles, fingers, feet, weight gain); less often - increased sweating, rarely - swelling of the tongue, fever.
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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Dolac, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Dolac is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!
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Reviews
Analogues of this product are better known to consumers. Popular drugs are Ketorolac, Ketanov, and Ketorol. But “Dolak” has an equally strong analgesic effect, and costs no more than 80 rubles. Many patients who have tried this treatment note that even the most severe pain responds to the effects of ketorolac, and although the pain does not go away immediately, it does not return for a long time.
There are especially many positive reviews about “Dolak” from those who suffer from arthritis, radiculitis, neuralgia, and muscle pain. After all, such pain is almost impossible to relieve with conventional analgesics. And “Dolak” is the most effective in this case.
Contraindications
The use of Dolac is contraindicated in case of hypersensitivity to the components of the drug and other non-steroidal anti-inflammatory drugs, during an exacerbation of peptic ulcer of the duodenum and stomach, with moderate and severe renal failure and the risk of its development due to dehydration or hypovolemia, with a history of gastrointestinal bleeding, perforation or ulcers, hemorrhagic stroke and conditions with a high risk of incomplete hemostasis or bleeding.
The drug is not prescribed in the preoperative period, as well as during surgery, since the risk of bleeding is high.
The simultaneous use of Dolak and other non-steroidal anti-inflammatory drugs, including aspirin and pentoxifylline, is prohibited.
The drug is not prescribed to children and adolescents under 16 years of age, women during pregnancy, childbirth and breastfeeding.
Indications for use
The drug Dolak is prescribed in the following situations:
- Toothache;
- Rheumatism (allergic-infectious diseases with disruption of the joints and cardiovascular system with the presence of acute pain);
- Arthralgia (severe pain in the joints);
- Stretching;
- Dislocations (changes in the joint capsule and ligamentous apparatus due to displacement of the articular ends);
- Radiculitis (inflammation of the nerve roots located in the intervertebral foramina);
- Myalgia (painful sensations in the muscles, causing shooting or aching sensations);
- Neuralgia;
- Oncological diseases (pain relief);
- Severe and moderate pain after operations, childbirth and injuries.
Dosage regimen
The drug in tablet form is prescribed to patients aged 16 to 64 years, weighing more than 50 kg at a dose of 20 mg for the first use, and then 10 mg 4 times a day. The highest dose that can be consumed per day is 40 mg.
For patients weighing less than 50 kg and suffering from renal failure, the drug is prescribed at a dosage of 10 mg 4 times a day. The maximum dose per day is also 40 mg.
The injection form of the drug for patients aged 16 to 64 years and weighing more than 50 kg is prescribed at a dose of 30-60 mg with an interval of 6 hours (in parallel, tablets are allowed). The permissible dosage for intravenous injection is 30 mg. The highest daily dose is 90 mg.
Patients with renal failure and weight less than 50 kg are prescribed intramuscular injections at a dose of 30 mg, intravenous injections - 60 mg.
The duration of therapy is 5 days.
Special instructions and precautions
Before starting therapy, it is necessary to get rid of hypoproteinemia, restore the volume of circulating blood, the balance of water and electrolytes.
If the pain syndrome is chronic, the drug is not used.
The manufacturer does not prohibit driving vehicles or engaging in other potentially hazardous activities. If you experience dizziness, insomnia or depression, you must be careful not to cause harm to yourself or others.
Prescription during pregnancy and lactation
During periods of pregnancy and breastfeeding, Dolak is contraindicated for women. If there is a need to use medication during lactation, you need to switch the child to store-bought formulas.
To reduce pain in obstetric practice, injections are not used, because Dolak can increase the duration of the initial period of labor, suppress the contractility of the uterus and worsen the blood circulation of the fetus.
Use in children and the elderly
The solution is only allowed to be administered to patients over 16 years of age.
The drug is prescribed for elderly people with caution and in minimal doses, since in patients of this group, plasma clearance decreases and the half-life increases.
For liver and kidney dysfunction
In these conditions, the solution is used with caution.
Drug interactions
Concomitant use of other NSAIDs, glucocorticosteroids and calcium supplements can lead to intestinal bleeding or damage to the mucous membranes of the digestive tract.
The use of paracetamol increases the negative effect on the kidneys.
Bleeding may occur when using thrombolytics, anticoagulants, cephalosporins, antiplatelet agents, and ASA.
Hematotoxicity increases during treatment with myelotoxic drugs.
Methotrexate worsens the negative effects on the liver and kidneys.
The use of Dolak can lead to an increase in the effect of narcotic painkillers, a weakening of the effectiveness of diuretics and blood pressure-lowering drugs.
Terms of sale and storage
Journalists regularly raise the problem that some pharmacies sell medications to everyone. Dolac is one of the drugs that cannot be sold without a prescription. Before starting treatment, you must visit a doctor.
The place where the solution is stored must be dry, dark, and inaccessible to children. The optimal temperature is +15…+25°C. The medicine retains its properties for 2 years.
Drug interactions
The combined use of other non-steroidal anti-inflammatory drugs leads to the development of undesirable side reactions.
Concomitant use of anticoagulants and pentoxifylline may increase the likelihood of bleeding.
ACE inhibitors increase the likelihood of renal dysfunction.
Concomitant use of probenecid increases the amount of ketorolac in the blood.
Parallel use of lithium preparations with the drug Dolak increases the amount of lithium in plasma and reduces renal clearance.
The combined use of furosemide and the drug Dolak reduces the diuretic effect of the former.
Prescribing ketorolac reduces the need to use opioid analgesics for pain relief.
Pharmacological properties
The drug Dolak exhibits analgesic, anti-inflammatory, antipyretic and antiaggregation effects. The analgesic effect of this medicine can be compared with the effect of morphine.
The analgesic effect of the drug develops 45 minutes after taking the tablet or intramuscular injection. The maximum effect develops after 1-2 hours.
The use of the drug helps to increase bleeding time, suppress thrombus aggregation and decrease the concentration of thromboxane.
