Erius - description of the drug, instructions for use, reviews

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Manufacturers: Schering-Plough Corp. (USA)

Active ingredients

• Desloratadine

Disease class

• Allergic rhinitis caused by pollen
• Other seasonal allergic rhinitis
• Idiopathic urticaria

Clinical and pharmacological group

• Not indicated. See instructions

Pharmacological action

• Antiallergic

Pharmacological group

• H1-antihistamines

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

An antihistamine (an active metabolite of loratadine ) has a long-lasting effect. Inhibits various reactions of allergic inflammation (release of pro-inflammatory cytokines, pro-inflammatory chemokines, production of superoxide anions, chemotaxis and adhesion of eosinophils, release of adhesion molecules, release of histamine, leukotriene C4, prostaglandin D2). Thus, it prevents the development and reduces the manifestations of allergic reactions. The drug has an antiexudative and antipruritic effect, reduces capillary permeability, relieves spasm of smooth muscles and tissue swelling.

The drug does not have a sedative effect and does not act on the central nervous system, does not affect psychomotor reactions. The effect of the drug, after oral administration, appears after 30 minutes and lasts throughout the day.

Pharmacokinetics

After oral administration, the drug is quickly and well absorbed into the gastrointestinal tract. In blood plasma it is determined after 30 minutes. Does not penetrate the BBB. There is no clinically significant accumulation when taking therapeutic doses. The maximum concentration in the blood is after 3 hours. Strong connection with blood proteins (85-87%). Metabolized in the liver to form desloratadine. A small portion (<2%) is excreted by the kidneys and (<7%) in the feces. The half-life is on average 27 hours.

Lozenges Aerius

Instructions for medical use of the drug

Description of pharmacological action

A selective blocker of peripheral histamine H1 receptors with a long duration of action that does not cause sedation. Desloratadine is the primary active metabolite of loratadine. Prevents the development and facilitates the course of allergic reactions, has antipruritic and antiexudative effects, reduces capillary permeability, prevents the development of tissue edema and smooth muscle spasm. Does not affect the central nervous system, does not have a sedative effect (does not cause drowsiness), does not affect the speed of psychomotor reactions. Does not cause prolongation of the QT interval on the ECG. When taken orally, Erius® selectively blocks peripheral histamine H1 receptors without penetrating the BBB. Erius® has a long-term (at least 24 hours) anti-allergic and anti-inflammatory effect by suppressing various reactions that underlie the development of allergic inflammation, including the following: the release of pro-inflammatory cytokines (including IL-4, IL-6, IL-8, IL-13), release of pro-inflammatory chemokines, production of superoxide anion by activated polymorphonuclear neutrophils; adhesion and chemotaxis of eosinophils; expression of adhesion molecules (including P-selectin, etc.); IgE-dependent release of histamine, PG D2 and leukotriene C4. The action of Erius® begins within 30 minutes after oral administration and continues for 24 hours.

Indications for use

- seasonal (hay fever) and year-round allergic rhinitis (elimination or relief of sneezing, mucus from the nose, itching and nasal congestion, itching and redness of the eyes, watery eyes, itching of the palate); - chronic idiopathic urticaria (reduction and elimination of skin itching and rash).

Release form

lozenges 2.5 mg; blister 5, cardboard pack 1; lozenges 2.5 mg; blister 6, cardboard pack 1; lozenges 5 mg; blister 5, cardboard pack 1; lozenges 5 mg; blister 6, cardboard pack 1; lozenges 5 mg; blister 5, cardboard pack 5; lozenges 5 mg; blister 5, cardboard pack 4; lozenges 5 mg; blister 5, cardboard pack 3; lozenges 5 mg; blister 5, cardboard pack 2; lozenges 5 mg; blister 5, cardboard pack 6; lozenges 5 mg; blister 5, cardboard pack 10; lozenges 5 mg; blister 5, cardboard pack 12; lozenges 5 mg; blister 5, cardboard pack 15; lozenges 5 mg; blister 5, cardboard pack 18; lozenges 5 mg; blister 5, cardboard pack 20; lozenges 5 mg; blister 6, cardboard pack 2; lozenges 5 mg; blister 6, cardboard pack 3; lozenges 5 mg; blister 6, cardboard pack 4; lozenges 5 mg; blister 6, cardboard pack 5; lozenges 5 mg; blister 6, cardboard pack 6; lozenges 5 mg; blister 6, cardboard pack 10; lozenges 5 mg; blister 6, cardboard pack 12; lozenges 5 mg; blister 6, cardboard pack 15; lozenges 5 mg; blister 6, cardboard pack 18; lozenges 5 mg; blister 6, cardboard pack 20; lozenges 2.5 mg; blister 5, cardboard pack 2; lozenges 2.5 mg; blister 5, cardboard pack 3; lozenges 2.5 mg; blister 5, cardboard pack 4; lozenges 2.5 mg; blister 5, cardboard pack 5; lozenges 2.5 mg; blister 5, cardboard pack 12; lozenges 2.5 mg; blister 5, cardboard pack 15; lozenges 2.5 mg; blister 5, cardboard pack 18; lozenges 2.5 mg; blister 5, cardboard pack 20; lozenges 2.5 mg; blister 5, cardboard pack 6; lozenges 2.5 mg; blister 5, cardboard pack 10; lozenges 2.5 mg; blister 6, cardboard pack 2; lozenges 2.5 mg; blister 6, cardboard pack 3; lozenges 2.5 mg; blister 6, cardboard pack 4; lozenges 2.5 mg; blister 6, cardboard pack 5; lozenges 2.5 mg; blister 6, cardboard pack 6; lozenges 2.5 mg; blister 6, cardboard pack 10; lozenges 2.5 mg; blister 6, cardboard pack 12; lozenges 2.5 mg; blister 6, cardboard pack 15; lozenges 2.5 mg; blister 6, cardboard pack 20; lozenges 2.5 mg; blister 6, cardboard pack 18; lozenges 2.5 mg; blister 5, cardboard pack 1; lozenges 2.5 mg; blister 6, cardboard pack 1; lozenges 2.5 mg; blister 5, cardboard pack 2; lozenges 2.5 mg; blister 5, cardboard pack 3; lozenges 2.5 mg; blister 5, cardboard pack 4; lozenges 2.5 mg; blister 5, cardboard pack 5; lozenges 2.5 mg; blister 5, cardboard pack 12; lozenges 2.5 mg; blister 5, cardboard pack 15; lozenges 2.5 mg; blister 5, cardboard pack 18; lozenges 2.5 mg; blister 5, cardboard pack 20; lozenges 2.5 mg; blister 5, cardboard pack 6; lozenges 2.5 mg; blister 5, cardboard pack 10; lozenges 2.5 mg; blister 6, cardboard pack 2; lozenges 2.5 mg; blister 6, cardboard pack 3; lozenges 2.5 mg; blister 6, cardboard pack 4; lozenges 2.5 mg; blister 6, cardboard pack 5; lozenges 2.5 mg; blister 6, cardboard pack 6; lozenges 2.5 mg; blister 6, cardboard pack 10; lozenges 2.5 mg; blister 6, cardboard pack 12; lozenges 2.5 mg; blister 6, cardboard pack 15; lozenges 2.5 mg; blister 6, cardboard pack 20; lozenges 2.5 mg; blister 6, cardboard pack 18; lozenges 5 mg; blister 5, cardboard pack 1; lozenges 5 mg; blister 6, cardboard pack 1; lozenges 5 mg; blister 5, cardboard pack 2; lozenges 5 mg; blister 5, cardboard pack 3; lozenges 5 mg; blister 5, cardboard pack 4; lozenges 5 mg; blister 5, cardboard pack 5; lozenges 5 mg; blister 5, cardboard pack 12; lozenges 5 mg; blister 5, cardboard pack 15; lozenges 5 mg; blister 5, cardboard pack 18; lozenges 5 mg; blister 5, cardboard pack 20; lozenges 5 mg; blister 5, cardboard pack 6; lozenges 5 mg; blister 5, cardboard pack 10; lozenges 5 mg; blister 6, cardboard pack 2; lozenges 5 mg; blister 6, cardboard pack 3; lozenges 5 mg; blister 6, cardboard pack 4; lozenges 5 mg; blister 6, cardboard pack 5; lozenges 5 mg; blister 6, cardboard pack 6; lozenges 5 mg; blister 6, cardboard pack 10; lozenges 5 mg; blister 6, cardboard pack 12; lozenges 5 mg; blister 6, cardboard pack 15; lozenges 5 mg; blister 6, cardboard pack 20; lozenges 5 mg; blister 6, cardboard pack 18;

Pharmacodynamics

Long-acting antihistamine, peripheral histamine H1 receptor blocker. Desloratadine is the primary active metabolite of loratadine. Inhibits the cascade of allergic inflammation reactions, incl. release of proinflammatory cytokines, including interleukins IL-4, IL-6, IL-8, IL-13, release of proinflammatory chemokines, production of superoxide anions by activated polymorphonuclear neutrophils, adhesion and chemotaxis of eosinophils, release of adhesion molecules such as P-selectin, IgE - mediated release of histamine, prostaglandin D2 and leukotriene C4. Thus, it prevents the development and facilitates the course of allergic reactions, has antipruritic and antiexudative effects, reduces capillary permeability, and prevents the development of tissue edema and smooth muscle spasm. The drug has no effect on the central nervous system, has virtually no sedative effect (does not cause drowsiness) and does not affect the speed of psychomotor reactions. Does not cause prolongation of the QT interval on the ECG. The action of Erius begins within 30 minutes after oral administration and continues for 24 hours.

Pharmacokinetics

Absorption After taking the drug orally, desloratadine is well absorbed from the gastrointestinal tract, with detectable concentrations of desloratadine in the blood plasma achieved within 30 minutes, and Cmax after approximately 3 hours. Distribution The binding of desloratadine to plasma proteins is 83-87%. When used in adults and adolescents for 14 days at a dose of 5 mg to 20 mg 1 time, no signs of clinically significant accumulation of desloratadine were detected. Simultaneous food intake or simultaneous consumption of grapefruit juice does not affect the distribution of desloratadine (when taken at a dose of 7.5 mg 1 time). Does not penetrate the BBB. Metabolism: Extensively metabolized by hydroxylation to form 3-OH-desloratadine combined with a glucuronide. It is not an inhibitor of CYP3A4 or CYP2D6 and is not a substrate or inhibitor of P-glycoprotein. Excretion Desloratadine is excreted from the body as a glucuronide compound and in small amounts (less than 2% in urine and less than 7% in feces) unchanged. T1/2 averages 27 hours (20-30 hours).

Use during pregnancy

Contraindicated during pregnancy. Category of effect on the fetus according to the FDA is C. Breastfeeding should be discontinued during treatment (passes into breast milk).

Contraindications for use

Hypersensitivity, pregnancy, breastfeeding. For syrup (additionally, due to the presence of sucrose and sorbitol): hereditary fructose intolerance, glucose/galactose malabsorption or sucrose/isomaltose deficiency.

Side effects

Pills. Increased fatigue (1.2%), dry mouth (0.8%), headache (0.6%). Very rarely - tachycardia, palpitations, increased activity of liver enzymes, increased bilirubin concentrations, allergic reactions, including anaphylaxis and rash. Syrup. In children under 2 years of age, the following adverse events were observed (the frequency was slightly higher than with placebo): diarrhea, increased body temperature, insomnia. In children 2–11 years of age, the incidence of side effects was comparable to placebo. In adults and adolescents over 12 years of age (frequency slightly higher than with placebo): increased fatigue, dry mouth, headache. When using desloratadine at the recommended dose of 5 mg/day, the incidence of drowsiness was no higher than when using placebo. Very rare side effects include dizziness, drowsiness, tachycardia, palpitations, abdominal pain, nausea, vomiting, dyspepsia, diarrhea, increased levels of bilirubin, liver enzymes in the blood serum, allergic reactions (anaphylaxis, angioedema, itching, rash, urticaria ).

Directions for use and doses

Film-coated tablets Adults and adolescents aged 12 years and older are prescribed 5 mg 1 time per day, regardless of meals, preferably at the same time of day. The tablet should be swallowed whole, without chewing, with a small amount of water. Syrup Children aged 1 to 5 years are prescribed 1.25 mg (2.5 ml of syrup) 1 time; children aged 6 to 11 years - 2.5 mg (5 ml syrup) 1 time; adults and adolescents over 12 years of age - 5 mg (10 ml of syrup) 1 time / The syrup is taken orally, regardless of meals, with a small amount of water.

Overdose

Symptoms: Taking a dose 5 times the recommended dose did not result in any symptoms. In clinical trials, daily use of desloratadine up to 20 mg for 14 days in adults and adolescents was not associated with statistically or clinically significant changes in the cardiovascular system. In a clinical pharmacological study, the use of desloratadine at a dose of 45 mg/day (9 times higher than recommended) for 10 days did not cause prolongation of the QT interval and was not accompanied by serious side effects. Treatment: in case of accidental ingestion of a large amount of the drug - gastric lavage, intake of activated charcoal; if necessary, symptomatic therapy. Desloratadine is not eliminated by hemodialysis; the effectiveness of peritoneal dialysis has not been established.

Interactions with other drugs

No clinically significant interactions with other drugs have been identified. Erius does not enhance the effects of ethanol on the central nervous system. Eating does not affect the effectiveness of the drug.

Precautions for use

The effect of desloratadine on the ability to drive vehicles and operate machinery has not been established.

Special instructions for use

Use in pediatrics The effectiveness and safety of using Erius in syrup form in children under 1 year of age has not been established. In most cases, rhinitis in children under 2 years of age is infectious in nature. There have been no studies of the effectiveness of Erius for rhinitis of infectious etiology. Differential diagnosis between allergic rhinitis and rhinitis of other origin in children under 2 years of age presents certain difficulties. When making a differential diagnosis, attention should be paid to the presence or absence of foci of infection or structural abnormalities of the upper respiratory tract, a thorough history, examination, and appropriate laboratory tests and skin tests. Effect on the ability to drive a car and operate machinery At the recommended dose, Erius® does not affect the ability to drive a vehicle or operate machinery.

Storage conditions

At a temperature not exceeding 30 °C.

Best before date

24 months

ATX classification:

R Respiratory system

R06 Antihistamines for systemic use

R06AX Other antihistamines for systemic use

R06AX27 Desloratadine

Indications for use

• Rapid relief of allergy symptoms, including rhinitis of allergic origin and seasonal hay fever (swelling of the mucous membrane of the nasopharynx, itching, sneezing, nasal congestion, rhinorrhea , conjunctival hyperemia, lacrimation, cough).
• Reduction of rash and skin itching in chronic idiopathic urticaria .

Indications for the use of the drug, on the recommendation of a doctor, can be expanded and prescribed for other allergic conditions and diseases.

Side effects

When taking tablets, you may experience increased fatigue, headache, dry mouth, nausea, and vomiting. Much less common - palpitations, tachycardia bilirubin concentration and liver enzyme activity, diarrhea, drowsiness, dizziness, local allergic reactions.

When taking syrup, children under 2 years of age may experience insomnia , diarrhea , and increased body temperature. Children over 12 years of age may experience increased fatigue, headache, and dry mouth.

Side effects of the drug Erius

In clinical studies, when using the drug Erius according to indications for use, including allergic rhinitis and chronic idiopathic urticaria at the recommended dose of 5 mg/day, the incidence of side effects was 3% higher than when using placebo. When using the drug Erius, the most common side effects (compared to placebo) were fatigue (1.2%), dry mouth (0.8%), headache (0.6%). Very rarely - hypersensitivity reactions (including anaphylactic reaction and rash), tachycardia, palpitations, increased activity of liver enzymes, bilirubin, hepatitis. When using syrup in children aged 6 to 23 months, diarrhea (3.7%), chills (2.3%) and insomnia (2.3%) were most often noted; in other age categories - increased fatigue (1.2%), dry mouth (0.8%), headache (0.6%).

Instructions for use of Erius (Method and dosage)

Erius tablets, instructions for use

Adults are prescribed one 5 mg tablet once a day. It is recommended not to chew the drug, but to swallow the tablet whole with water. The duration of taking the drug is determined by the course and severity of the disease. Most often, treatment is stopped after relief of the symptoms of the disease, but it can be long-term for allergic rhinitis throughout the entire period of contact with the allergen.

Erius syrup, instructions for use

Children from 6 months to five years are prescribed 2.5 ml of syrup once a day. For children 6 to 11 years old, 5 ml of syrup, and for adolescents over 12 years old, the medicine is prescribed in a dose of 10 ml once a day. Drops of syrup must be washed down with water.

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** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Erius, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

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** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Erius is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

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Erius for children

Prescribing antiallergic drugs of the 2nd and 3rd generations is more appropriate in children. It is important that the drug has no effect on psychomotor functions or cardiotoxicity. It is highly safe for children and has a special release form for this age category.

The instructions for Erius syrup for children indicate that syrup for children is contraindicated for children under 6 months, and tablets for children under 12 years of age, since the safety of its use has not been established. The important thing is that with long-term use, the effectiveness of the drug is maintained and there is no need to replace it with another drug. This is important in the treatment of chronic allergic diseases, which sometimes require constant use.

Erius syrup for children, reviews of which are positive, are often prescribed for allergic rhinitis . Parents note that in the first week of treatment, nasal discharge, itching and sneezing decrease, and symptoms, including nasal congestion, are completely relieved after 2 weeks. In children with atopic dermatitis, there was a disappearance of itching on the 5th day, and a decrease in rashes on the 7th day.

Special instructions for the use of the drug Erius

The effectiveness and safety of using syrup in children under 6 months of age and tablets in children under 12 years of age has not been fully established. In clinical and pharmacological studies, Erius did not enhance the effects of alcohol such as impaired psychomotor function and drowsiness. Psychomotor test results did not differ significantly between patients who received Erius and placebo alone or with alcohol. During pregnancy and breastfeeding. Erius is not recommended for use during pregnancy, since the safety of the drug in pregnant women has not been established. Desloratadine passes into breast milk, so it is recommended to stop breastfeeding during treatment with the drug. effects on the ability to drive vehicles or operate complex machinery .

Analogues of Erius

Level 4 ATX code matches:
Dezal

Histaphene

Clarisens

Telfast

Claridol

Claritin

Loratadine

Fexofast

Peritol

Desloratadine

LauraHEXAL

Clarotadine

Rupafin

Ciel

Dramamine

Lordestin

Lomilan

Fenkarol

Kestin

Loratek

Analogues of Erius, which have the same active substance and ATX code: Alergomax , Alernova , Alersis , Allergo -Norm , Allergostop , Desloratadine , Desorus , Lordes , Lordestin Trexil Neo , Telfast , Fribris , Edem , Eridez and others.

The price of analogues varies widely; there are analogues at a higher and lower price than Erius, but in many ways, the price depends on the manufacturer, packaging, and the number of tablets in the package. If the patient has a special sensitivity desloratadine For example, the drug "Zodak" can be used as an analogue of "Erius" syrup.

Which is better: Erius or Telfast?

Telfast belongs to the second generation of (non-sedating) antihistamines. These 2 drugs differ in the active substance, in this case it is fexofenadine , which is not metabolized in the body, so its pharmacokinetics do not change if liver and kidney function are impaired. Maximum safe. The effect appears after 1 hour, and maximum after 6 hours. The terminal half-life is 11-15 hours, so in some cases the drug is prescribed 2 times a day. There is no syrup form, which limits use in young children. The drug can be used in children over 6 years of age (30 mg tablets).

Desloratadine , the active ingredient in Erius, is the only H1-histamine receptor blocker that has shown in studies a decongestive effect - it reduces nasal congestion in seasonal allergic rhinitis . Effective for a combination of allergic rhinitis and bronchial asthma , as well as for chronic urticaria . In terms of activity against H1 receptors, Erius is 3-4 times superior to second generation drugs. Its important property is the presence of anti-inflammatory activity. The action begins after 30 minutes and reaches a maximum after 1 hour. The long half-life provides a therapeutic effect throughout the day. Characterized by a high level of safety. It does not cause negative effects on the cardiovascular system and is well tolerated. It is used in children from 1 year (syrup) and over 12 years (tablets).

What to choose: Lordestin or Erius?

Lordestin and Erius have the same active ingredient - desloratadine, and apparently the effectiveness of the drugs is the same. Available in the same dosage, the half-life is up to 27 hours, so it is taken once a day. There is no syrup form. The drug is taken by children from 12 years of age.

The drugs differ in manufacturer and cost. Lordestin is a generic, manufactured by Gedeon Richter-RUS (Russia), the cost of 30 tablets is 752 rubles. The second drug is original, manufactured by Schering-Plough Labo NV (Belgium), the cost of 10 tablets is 548 rubles.

pharmachologic effect

Erius is an antihistamine - a drug that blocks histamine receptors in the body, which leads to inhibition of allergic reactions. The active substance of Erius selectively acts on neurotransmitters that influence the blistering-hyperemic reaction of the skin, itching, etc., without penetrating the blood-brain barrier. Research has proven that the use of Erius can suppress the following body reactions:

• Production of pro-inflammatory chemokines and cytokines;
• Eosinophilic granulocyte adhesion and chemotaxis;
• IgE-dependent release of histamine, prostaglandin D2 and leukotriene C4;
• Increased adhesiveness of P-selectin;
• Development of acute bronchospasm-atopic nature (in experiments involving animals).

The drug has antipruritic, antiallergic and antiexudative effects, preventing the occurrence and easing the course of allergic reactions. Erius effectively relieves spasms of smooth muscles and prevents the appearance of tissue swelling.

Reviews of Erius do not note the appearance of a pronounced sedative (calming) effect. In addition, clinical studies have shown that taking Erius at a dosage of 20 mg/day for 2 weeks does not have a significant effect on the functioning of the cardiovascular system. Unlike other antihistamines, the effectiveness of Erius is not affected by the consumption of fatty foods or grapefruit juice.

Reviews about Erius

Reviews of Erius tablets

In most reviews, patients speak of the drug as a good remedy.

• “... I have been an allergy sufferer since I was 16 years old. Dust mite allergy. I constantly do wet cleaning. I have tried all sorts of allergy pills. Now I’m taking Erius - it’s an excellent medicine for allergies, you could say it’s my salvation. Quickly suppresses the effect of allergens, there is no drowsiness. After completing the ten-day course, I do not feel allergy attacks. I can visit you freely without any problems.”

Reviews of Erius syrup

Reviews are varied, but mostly positive.

• “... The child is 14 months old. Allergy from birth, manifested by swelling and rash. The doctor prescribed syrup and told me how to take it. A wonderful result, on the second day the allergy symptoms disappear, we can walk with the baby as much as we want. The effect after the course of treatment lasts for another 10-15 days. We took 2 courses, the allergy symptoms after its discontinuation became less pronounced. The syrup tastes good, the child drinks it without objection.”

Reviews from doctors

A drug with clinically significant antiallergic properties and proven anti-inflammatory activity. It inhibits the development of the initial phase of the allergic response, relieves allergic inflammation, thereby increasing the quality of life of patients. Good tolerability and a high degree of safety allow us to recommend the drug for the treatment of adults and children with allergic seasonal rhinitis and chronic urticaria. With long-term use of Erius, resistance to it does not arise, which allows it to be prescribed for a long period (up to a year) for diseases such as allergic rhinitis, atopic dermatitis, and bronchial asthma.

Erius price, where to buy

The price of Erius in tablets 5 mg No. 7 in Moscow pharmacies varies between 365 -460 rubles per pack; No. 10 - from 482 to 628 rubles.

The price of Erius syrup 2.5 g in a 60 ml bottle ranges from 525 to 646 rubles; A 120 ml bottle of syrup for children costs from 670 to 870 rubles per package.

The price of Erius in Ukraine for tablets No. 7 varies between 167 – 226 hryvnia; No. 10 —240 -258 hryvnia per package. Drops (syrup) in a 60 ml bottle in pharmacies in Ukraine (Kyiv) costs an average of 180 hryvnia; in a 120 ml bottle - 328 hryvnia. These allergy pills can be bought in other cities of Ukraine. Their cost in pharmacy chains in Dnepropetrovsk or Odessa is almost the same as their price in Kyiv.

You can buy all forms of the drug without difficulty in most pharmacies in Moscow and other Russian cities, as well as in the pharmacy chain of Ukraine.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Erius tab.
  p.p.o. 5 mg n10Schering-Plough Labo NV RUB 583 order
• Erius syrup 2.5 mg/5 ml 60 ml Schering-Plough Labo NV

  RUR 575 order

Pharmacy Dialogue

• Erius tablets 5 mg No. 10Shering-Plough

  RUR 618 order

• Erius syrup 60mlShering-Plow

  RUR 622 order

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Pharmacy24

• Erius 5 mg N10 tablets Schering-Plough Labo N.V., Belgium
  223 UAH.order
• Erius 60 ml 0.5 mg/ml syrup Schering-Plough Labo N.V., Belgium

  161 UAH order

PaniPharmacy

• Erius tablets Erius film-coated tablets 5 mg No. 10 Belgium, Schering-Plough Labo

  281 UAH order

• Erius liquid Erius syrup 60ml Belgium, Schering-Plough Labo

  216 UAH order

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Release form and composition

The active ingredient is desloratadine. Excipients in the composition depend on the dosage form. Available in the form of tablets and syrup.

Pills

The amount of active substance in 1 tablet is 5 mg. Additional ingredients: calcium dihydrate, corn starch, talc.

Syrup

The amount of desloratadine in 1 ml of syrup is 0.5 mg. Additional components: sorbitol, purified water, sodium dihydrate, sodium benzoate, sucrose, yellow color and flavor.