Today, there are a huge variety of diseases of the genitourinary system, as well as diseases that arise due to sexually transmitted infections.
Of course, women are more often exposed to this type of disease than men. This is due to many reasons: a weakened immune system, hormonal imbalance, colds and much more.
Cystitis is one of the most common diseases that occurs in women. Unfortunately, if the disease appears at least once in a woman, then in the future, with the slightest cold, all the symptoms inherent in this disease may occur.
On the drug market, manufacturers offer a wide range of different drugs that can cope with difficulties in the shortest possible time without causing harm to the body, including the stomach. This is extremely important.
Because often, medications that can instantly solve a problem usually contain potent components. Such components have a negative effect on the gastrointestinal tract and can cause side effects.
What drug is best to choose if cystitis causes discomfort and worsens more and more?
pharmachologic effect
The medicine belongs to the group of nitrofurans , it is an antimicrobial drug. Bactericidal and bacteriostatic effects are achieved by disrupting the process of protein synthesis in bacteria and the permeability of the cell membrane. Furadonin demonstrates activity against a number of gram-positive and gram-negative bacteria (these are Shigella , streptococci , staphylococci , Escherichia coli , etc.). Effective in the development of urinary tract infections.
During treatment with this drug, bacterial resistance rarely develops, but with prolonged use of the drug, resistance is still possible.
The most pronounced drug activity is observed in acidic urine. If the urine pH is 8 or more, the bactericidal activity of the product is noticeably reduced.
Answering the question whether Furadonin is an antibiotic or not, it should be noted that this drug is not an antibiotic.
Operating principle
Speaking about the principle of action of such a drug as Furadonin, it should be noted that this drug belongs to the group of synthetic antimicrobial drugs.
Furadonin is a fast-acting drug. Perhaps this is where the most important advantage lies. After all, for a woman who suffers from pain, it is very important to achieve results as soon as possible. It is this type of drug that becomes a real salvation for women.
The principle of action of the drug furadonin is quite simple, but very effective. The drug is based on a component such as nitrofurantoin. Directly this component, when it enters a woman’s body, begins its active action, namely, the fight against infection.
The action of the drug is carried out directly through the lymph. It is for this reason that the drug begins to act within three to four hours after administration. The big advantage is that the tablet of the drug Furadonin begins to be absorbed by the intestines instantly.
This process is not at all the end of the principle of action of the medicine. Microorganisms, which are extremely necessary to get rid of, begin to die due to disruption of the cell-type membrane permeability process. Also, the process of influence of the drug is facilitated by the process of protein compounds carried out directly in bacteria.
The big advantage is that this drug has a milder effect than antibiotics, which can cause side effects and failure in the body system. This drug also works on the principle of selecting cells that are directly related to the disease and which are extremely necessary to get rid of.
Indications for use of Furadonin
Before starting treatment, the patient must understand what Furadonin tablets are and what they help with. The following indications for the use of Furadonin are determined:
- infectious-inflammatory diseases of the urinary tract, which are provoked by microorganisms sensitive to Furadonin ( urethritis , pyelonephritis , cystitis , pyelitis);
- For the purpose of prevention, it is used during cytoscopy , urological surgical interventions, catheterization .
Before you start treatment with Furadonin, you should find out from a specialist what these tablets are for and how to take them.
Cystitis - what is it?
Before you start talking about any effective medications, you need to understand what cystitis is and what this disease is.
Very often, women feel pain when urinating, a frequent desire to urinate and discomfort in the bladder area. As a rule, with such symptoms, we can safely say that it is cystitis. Such a disease is precisely accompanied by such symptoms.
The disease cystitis is, first of all, an inflammatory process. In the event of such a disease, first of all, the bladder becomes inflamed. In addition, a process of damage to the mucous membrane occurs. That is why the disease is accompanied by the symptoms described above.
Cystitis is an insidious disease that often occurs unexpectedly for women. After all, girls today do not pay due attention to their health. For the formation and development of cystitis in a woman’s body, she will need to catch a cold quite a bit.
Factors contributing to the occurrence of cystitis:
- Women wear low-waisted jeans, leave open, bare backs unattended, wear short jackets and sit on the surface in the cold season. All this can contribute to the formation of a disease such as cystitis.
- If a woman suffers from infectious diseases of the reproductive system , then cystitis can only be a complication of existing diseases. The worst thing is when cystitis develops into a chronic form and worsens with the slightest cold or weakened immune system.
- A weakened immune system can also cause the formation and development of cystitis. After all, when the immune system weakens, all possible diseases are attracted like a magnet.
Now we can conclude that cystitis is not only an insidious disease that can “grasp” a woman’s body for a long time, but also the cause of the development of sexually transmitted infections and their complications.
To get rid of cystitis, you first need to determine the cause of the formation and development of such a disease. To solve the problem, you will need to take tests and, based on the results, select a drug that can cope with the disease as quickly as possible without harming the woman’s health.
Contraindications
The following contraindications to the use of the drug are determined:
- high sensitivity to the drug;
- chronic renal failure ;
- chronic heart failure of the second or third degree;
- cirrhosis of the liver;
- acute porphyria ;
- hepatitis in chronic form.
Also contraindications to taking Furadonin are the period of pregnancy and lactation, the age of the child under 1 month.
Advantages of the drug
The main advantage of the medicine is that it has long been known and proven. It also has good digestibility and is characterized by active absorption from the gastrointestinal tract. It has high bioavailability; in plasma it reacts with proteins by 60%. Metabolism of the active substance occurs in muscle tissue and liver. In addition, the drug is not addictive and is excreted from the body in the urine.
Another plus is the affordable price of the medicine. It is always on sale and available without a prescription.
People who drive or engage in vigorous activities should be aware that taking nitrofurantoin may cause dizziness.
Side effects
During treatment with this drug, the following side effects may develop:
- allergic manifestations (chills, rash , Quincke's edema, etc.);
- disturbances in the functioning of the respiratory system (cough, eosinophilia, pain in the chest, pulmonary infiltrates, decreased respiratory function, asthma attacks in people with a of bronchial asthma );
- disturbances in the functions of the digestive system (vomiting, anorexia, nausea, epigastric discomfort, in rare cases - hepatitis, jaundice, diarrhea );
- disturbances in the functioning of the nervous system ( dizziness, headache , drowsiness );
- disturbances in the functioning of the hematopoietic system (granulocytopenia, leukopenia, thrombocytopenia, agranulocytosis, anemia);
- skin reactions (erythema multiforme, dermatitis );
- other disorders (arthralgia, anaphylaxis, myalgia, drug fever, superinfection of the genitourinary tract).
If the side effects described above occur during treatment, you should definitely consult a doctor.
Furadonin tablets, instructions for use (Method and dosage)
Instructions for use of Furadonin stipulate that the drug should be taken with plenty of liquid, preferably taken after meals. Since the tablets have a bitter taste, chewing them is not recommended, especially for children. The highest daily dose for adult patients is 0.6 g, a single dose is 0.3 g.
Instructions for use for adult patients include taking 0.1-0.15 g of medication 3-4 times a day.
For uncomplicated infectious diseases, Furadonin should be taken 50 mg three times a day.
Patients with acute urological diseases take the drug for 7 to 10 days. If no improvement in the patient’s condition is observed during the period of therapy, further treatment with the drug is not advisable. In order to prevent relapses of diseases and for prophylaxis, the drug should be taken in a dose of 1-2 mg per 1 kg of weight.
Instructions for use for children
For children, the medicine is prescribed at the rate of 5-7 mg per 1 kg of child weight per day. The total dose should be divided into 4 doses. With long-term use for the purpose of prevention, it is enough to take a dose of 1 mg per 1 kg of weight per day.
Those who are interested in how to take Furadonin should note that the effect of the drug on the body becomes more pronounced in an acidic environment, so it is recommended to prefer protein foods during treatment.
The medicine Furadonin is widely used for cystitis. A specialist will tell you in detail how to take Furadonin for cystitis in each specific case. Treatment of cystitis with Furadonin tablets is practiced for both acute and chronic forms of the disease. As a rule, taking 3-4 tablets of the drug per day is indicated (unless the doctor has prescribed a different regimen on how to take tablets for cystitis).
How to take Furadonin
The medicine has a bitter taste, so it is not recommended to chew the tablets. The bottle of suspension should be shaken well before use, then measure the dose of nitrofurantoin with a glass or spoon. The suspension can be combined with milk, water, juice - this reduces discomfort in the stomach. According to the instructions, Furadonin tablets for pyelonephritis should be taken with plenty of water . The effect of nitrofurantoin is enhanced in an acidic environment, so it is recommended to consume more protein foods.
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Pills
The recommended dose of the drug for adults is 50-100 mg, 4 times a day. The maximum dosage is 600 mg/day, single dose – 300 mg. The course of treatment lasts seven days, it is possible to continue therapy for another three days, provided that the urine reaction has been monitored for sterility. After long-term treatment, the dose of the drug is gradually reduced. Maintenance therapy includes 50-100 mg tablets once a day; for prevention, it is recommended to take 50 mg four times a day during operations for urological diseases and the same dose three days after.
Suspension
According to the instructions, children are recommended to take the medicine in the form of a suspension. The dosage of the synthetic drug is calculated based on the child’s weight - 5-8 mg of the drug is taken per kg of body weight. The resulting daily amount of medication is divided into four doses. The duration of suspension therapy is a week. After this, the doctor conducts a urine test for sterility, performs a culture for the presence of microorganisms, and, if necessary, schedules an appointment for another three days.
Powder
The powder form of the medicine is rarely used, dissolves in liquid and is taken for cystitis. Furadonin is prescribed in the amount of 50-100 mg four times a day for adults, the course of treatment is 7-10 days. The maintenance dose for urological infections is considered to be 50-100 mg 1 time per day (best taken at night). This dosage is used to prevent exacerbations or in the chronic course of the disease. Maintenance therapy can last year-round, the minimum duration is three months.
Interaction
You should not simultaneously take Furadonin and antacid preparations containing magnesium trisilicate , as well as nalidixic acid , as this reduces the antibacterial effect of the drug.
You cannot combine the medicine with fluoroquinolones .
Drugs that block tubular secretion due to a decrease in the concentration of nitrofurantoin in the urine reduce the degree of antimicrobial effect of the drug and also increase the concentration of this substance in the blood, which leads to increased toxicity of the drug.
The antibacterial effect of Furadonin decreases in alkaline urine. Therefore, there is no need to take this remedy in parallel with medications that increase urine pH.
The process of elimination of Furadonin from the body is reduced by Sulfinpyrazone and probenecid , therefore, the simultaneous use of these drugs is undesirable.
Advantages of the drug
During treatment with Furadonin, as well as with Furagin, there is no suppression of the body’s overall immunological resistance (this occurs when taking antibiotics). On the contrary, nitrofurans significantly increase the degree of immunity. This is facilitated by the fact that the phagocytic activity of leukocyte bodies increases.
The drug "Furadonin" increases the complementary binding characteristics of blood serum, as well as the absorption-adsorption capacity of the RES of the liver and spleen.
When using the drug, post-vaccination immunity is not formed, since strains of pathogenic microorganisms practically do not develop resistance to the active substance. Treatment requires a lower concentration of the drug in the blood than when using antibiotics.
This medicine is often used to re-treat and prevent relapses.
In addition, there is another undeniable advantage that Furadonin has - the price, reviews of which indicate that this drug is accessible to a wide variety of categories of the population. Also, numerous comments on various medical forums indicate that the discomfort disappears by the end of the first day after taking this medication. In addition, the average cost of a medicine in pharmacies in our state is approximately 110 rubles.
special instructions
It should be taken into account that in people suffering from hypovitaminosis B, anemia, diabetes, electrolyte imbalance during treatment with Furadonin, the likelihood of peripheral neuropathy .
Not used for the treatment of prostatitis , purulent paranephritis .
To reduce the risk of side effects from the gastrointestinal tract, the drug should be taken with food or milk.
Nitrofurantoin should not be prescribed together with medications that can cause renal dysfunction.
Furadonin's analogs
Level 4 ATX code matches:
Furagin
Furamag
There are no structural analogues of Furadonin. There are a number of analogues of this drug according to the mechanism of therapeutic action. These are the drugs Furasol , Furagin , Furazidin , Furamag .
Furadonin or Furagin - which is better?
Furagin belongs to the same group (nitrofuran derivatives). The indications for use of both drugs are similar, and at the same time they provoke the development of almost identical side effects. It is generally accepted that Furagin is a milder medicine. But the final decision on the choice of drug should be made only by a specialist, which requires consultation with a doctor.
General information about preparentiotic
"Furadonin" is a representative of the group of active nitrofurans, has an antimicrobial effect and is prescribed for diseases of the urinary tract. The spectrum of action of the drug is very wide, despite the fact that it has an intensive effect on bacteria, which means that the result of its use will be positive. It helps not only in the treatment of cystitis. The instructions for use of Furadonin also indicate other ailments that can be treated with the participation of this remedy. But since the main target of this drug is still bladder diseases, we will touch on them right away.
Furadonin during pregnancy and lactation
Furadonin during pregnancy increases the risk of developing hemolytic anemia in the baby. The active substance passes through the placenta and has a toxic effect on the fetus. In some cases, Furadonin is used to treat pregnant women after 12 weeks, but only strictly as directed and after comparing the possible risks and benefits. If you are breastfeeding , you should not use this medicine because its active substance passes into breast milk.
Effect of the drug
When using Furadonin in the form of tablets orally, the active substances are quickly absorbed into the intestinal cavity within 3-4 hours. After this, nitrofurantoin, which is its active ingredient, enters the lymph and blocks the spread of infection. Furadonin tablets (what they are taken for and how will be described below) have a direct effect on the enzymes of microbial cells that transport hydrogen molecules. Thus, metabolic processes in bacteria are destroyed, which provokes the complete destruction of pathogenic microorganisms.
This drug, unlike antibiotics, does not have a systemic effect on microflora. Its effect is selective and applies only to a certain range of microorganism strains.
The local effect on the urinary organs not only stops the increase in pathogenic microorganisms, but also significantly increases overall immunity. Therefore, during the use of Furadonin, other inflammatory processes in the human body are also eliminated. When treating cystitis, for example, the medicine also has a beneficial effect on organs such as the kidneys, urethra and urinary ducts.
Since Furadonin is characterized by antiseptic properties, it promotes wound healing and treatment of lesions in internal organs.
Reviews about Furadonin
Reviews about Furadonin are mostly positive: patients write about the high effectiveness of the product. Reviews of Furadonin for cystitis indicate that this remedy allows you to get rid of unpleasant symptoms within a few days. There are also positive reviews that the drug is relatively cheap. However, quite often there is information from patients about the manifestation of side effects: headaches , nausea , vomiting , dizziness , etc.
Analogues for women
Especially for women, there are analogues of Furadonin - furamag, avexima, monural, nitroxoline, furatsilin, nolitsin, furazolidone, canephron. These drugs are substitutes similar and analogous to the drug in question and are essentially the same thing.
Furagin or furadonin which is better?
The questions of what is better than furagin or furadonin and which drug provides faster treatment can only be answered by the attending physician, since these are drugs of the same antimicrobial synthetic group. This means which one is best suited depends on the individual characteristics of the body.
Reviews
Reviews from patients and doctors about the drug are mostly positive. In addition, veterinarians successfully prescribe it for cats and dogs if there are symptoms of bacterial infection.
Contraindications
Contraindications – individual intolerance to individual components of the product, allergic reactions, liver and kidney diseases during exacerbation, cardiovascular diseases, pregnancy, children under 6 years of age. Drinking furadonin and alcohol at the same time is extremely undesirable.
Side effects may include nausea, dizziness, weakness and other symptoms that disappear after discontinuation of the drug. An overdose is characterized by vomiting and nausea; the patient needs to lavage the stomach and take large amounts of liquid.
Furadonin price, where to buy
The price of Furadonin 50 mg tablets is on average 55 rubles. per pack 10 pcs. The average price of Furadonin 100 mg is 100 rubles. per pack 20 pcs.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Furadonin tablets 100 mg 20 pcs. Olainfarm JSC
160 rub. order - Furadonin Avexima tablets 50 mg 20 pcs. JSC Irbitsky Chemical Plant
99 RUR order
- Furadonin Avexima tablets 100 mg 20 pcs. JSC Irbitsky Chemical Plant
RUB 179 order
- Furadonin tab. 50 mg 20 pcs. YuzhPharm LLC
109 rub. order
- Furadonin Avexima tablets 50 mg 10 pcs. JSC Irbitsky Chemical Plant
65 rub. order
Pharmacy Dialogue
- Furadonin tablets 100 mg No. 20Olainfarm OA
RUB 161 order
- Furadonin Avexima tablets 50 mg No. 20 Irbitsky HFZ
101 rub. order
- Furadonin Avexima tablets 50 mg No. 10 Irbitsky HFZ
61 rub. order
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Pharmacy24
- Furadonin 0.1g No. 20 tablets AT "Olainfarm", Latvia
49 UAH. order
PaniPharmacy
- Furadonin tablets Furadonin tablets 0.1g No. 20 Latvia, Olainfarm JSC
51 UAH order
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