Isofra nasal spray (reviews). Instructions for use and detailed description

Release form and composition

The drug "Isofra", which has varied reviews, is produced in the form of a nasal spray with a dispenser that regulates the uniform flow of the drug into the nasal cavity. Thanks to this form, the medicine can reach the most difficult to reach places. The drug contains the active ingredient - framycetin sulfate in the amount of 12.5 ml per 800,000 units. The volume of the bottle is 15 ml. The manufacturer of the drug is a French pharmaceutical company.

The complete set includes:

• paper box;
• 15 ml plastic container with the drug “Isofra”;
• instructions.

Reviews about this product say that it can be bought at every pharmacy, it is available only with a doctor's prescription and costs about 150 rubles.

Price

The difference between Isofra antibiotic spray is that it can be combined with other antimicrobial nasal drops. In Russia, prices for healing sprays for professional therapy vary between 400-800 rubles. Isofra nasal spray (15 ml) - the medicine can be ordered online, then the price will be inexpensive. How much does Isofra cost if you buy it in an online pharmacy?

Russian analogues

Many patients, before using Isofra spray, which has a wide variety of reviews, look for a Russian analogue containing the same active ingredient, but the price of which is significantly lower. This category of people will be disappointed, since at the moment there is no complete analogue of this drug in Russia.

In its properties, the medicine is similar to Bioparox, which contains the antibiotic component fusafungin, and also has common features with Polidex, which contains antibiotics such as neomycin, polymyxin B and the corticosteroid dexamethasone. The latter also has a vasoconstrictor, antiseptic and antihistamine effect, which is very effective for allergies. Framinazin also has a similar composition, which has a similar effect. This drug causes the death of pathogenic microbes and has an antiseptic effect.

A replacement for the drug “Isofra” can be “Protargol”, which is a good cure for runny nose and sinusitis. This medicine has a completely opposite composition and contains silver ions. "Protargol" is recommended for those people who are allergic to Isofra spray. Vibracil is no less effective for combating diseases of the upper respiratory tract. It relieves allergic nasal congestion, cures rhinitis of various forms, but has a lot of contraindications - vascular and heart diseases, diabetes, atrophy of the nasal mucosa, closed glaucoma and much more.

So if the doctor prescribed Isofra, then you should buy this particular drug. And you should not replace it yourself with another product.

Pharmacology of the spray

A bactericidal effect on pathogenic microorganisms is characteristic of the drug “Isofra”. Reviews say that this process affects gram-positive and gram-negative bacteria. The drug has found its purpose for acute viral diseases of the upper respiratory tract associated with staphylococcal, Escherichia coli and Haemophilus influenzae, Klebsiella, Shigella, Proteus and a number of similar infections. The drug "Isofra", unfortunately, is absolutely powerless against diseases caused by treponema, anaerobic or streptococcal bacteria.

The active substance framycetin, penetrating deep into the cellular tissue of pathogenic microorganisms, reduces the synthesis of the protein they produce. As a result of this, pathogenic cells are destroyed and die, and the disease disappears without a trace.

Indications and contraindications for use

The drug has a narrow area of ​​action and can be used in therapeutic treatment either as a stand-alone drug or in combination with other drugs. So, “Isofra” is effective for sinusitis (reviews keep saying this), as well as rhinitis, where the nasal mucosa suffers from infection. Good results were seen with nasopharyngitis and other complicated forms of the common cold. Isofra has a good effect for sinusitis. Reviews say that in this case you need to carefully read the instructions for the drug, which emphasize that the drug can be used only in the absence of all kinds of deformations in the nasal septum. The medicine is also used for such advanced forms of sinusitis as frontal sinusitis and ethmoiditis.

The spray is used for the prevention and treatment of postoperative inflammatory processes when the body's immunity is weakened. There is a special positive effect of the drug that is not comparable with any other medicines.

In any case, self-prescription of this drug should be completely excluded, especially when treating children's runny nose. Reviews about Isofra confirm this aspect. For children, Komarovsky recommends using more gentle treatment methods and only in rare cases resorting to antibiotics of a similar nature.

Isofra nasal drops, reviews of which are not always positive, are prohibited from use:

• with high sensitivity to antibiotics of the aminoglycoside group, including framycetin;
• during pregnancy;
• during breastfeeding;
• under the age of 2.5 years;
• with renal failure.

During pregnancy, the drug can disrupt the embryonic development of the fetus, and it easily passes into breast milk, which negatively affects the condition of the child.

There is a small probability of suppression of the microflora of the nasal mucosa with the subsequent development of dysbiosis, which causes particular caution when using antibiotics, especially in childhood.

Mode of application

Isofra is used for patients of any age. Adults can take single injections of the spray 4-5 times a day. The child is treated with 1 injection 3 times a day. This is done after hygienic cleaning of the nose - blowing your nose (especially with “green snot”). Treatment continues on average for a week, but in special cases, therapy can be carried out for up to 10-12 days.

During pregnancy and breastfeeding

Since Isofra has not been subjected to thorough clinical studies, the effects of its components on the fetus have not been studied.

However, there is reason to argue that Isofra cannot harm the fetus during pregnancy (taking into account even the 1st trimester of gestation), since the drops, if they enter the bloodstream, do so in very small quantities. Accordingly, if it is possible to overcome the placental barrier, the concentration of the drug is so low that it cannot have any teratogenic effect.

Treatment of a breastfeeding patient can be carried out without any restrictions. Again, its possible concentration in breast milk is low.

Spray "Isofra": instructions for use

Reviews about the drug say that its use must be supervised by a doctor, since this medicine is an antibiotic. Experts recommend using the spray for about a week, but no more than 10 days. If the patient’s condition has not improved during this time, another drug should be prescribed or the diagnosis of the current illness should be rechecked.

To use the drug, spray the spray into each nostril once. Adults should irrigate their nose with Isofra 5-6 times during the day. Reviews recommend that for children aged 2.5 to 15 years, the proportion should be halved, that is, used no more than three times a day, one spray into the nose.

During the procedure, the bottle is kept in an upright position to avoid getting the product into the eyes, ears or other area of ​​the face. The head should be tilted slightly. Next, insert the tip of the dispenser into the nostril and press. The nasal cavity must first be cleared of crusts, mucus and thoroughly rinsed. Only in this case can the maximum effect be achieved.

Do not use Isofra for rinsing the nasal cavity for sinusitis, and also do not use the drug together with antifungal agents, as they reduce the effect of the antibiotic. If there is no result within three days, then you need to contact a specialist to review the already prescribed treatment.

Recommendations

If a mother decides to use this drug, she should adhere to the following rules:

• Firstly, Isofra should be used immediately after feeding the baby.
• Secondly, you must strictly adhere to the frequency of administration and dosage indicated by the doctor.

As a rule, treatment with this drug lasts 5-7 days. Isofra is used in combination with other medications for better effect.

If the baby has a reaction during treatment, it is better for the mother to stop treatment immediately to avoid consequences.

But such reactions were recorded extremely rarely. Isofra has a large number of analogues . These include Polydex, but due to its composition, this analogue has many more contraindications. It is prohibited for pregnant and nursing mothers. Among all drugs of this type, Isofra is considered the safest.

Special instructions for use

Before using Isofra spray to treat sinusitis, you need to undergo a special examination by a doctor and pass the appropriate tests. It would be a good idea to check the body’s reaction to the antibiotic in advance. In the absence of contraindications and provided the drug is prescribed by a doctor, you can safely use it in the treatment of runny nose in both children and adults.

It is worth strictly regulating the use of the drug "Isofra" and not using it often, since there is a possibility of the emergence of strains of microorganisms on which this drug cannot act.

The drug should be stored in a dark place, out of reach of children, at room temperature not exceeding 25°C. The shelf life during which this product should be used is three years.

Safe first aid kit: what is the shelf life of Isofra drops and spray before and after opening? Storage conditions

Isofra is a nasal antibiotic that is used only as prescribed by a doctor. It has the destroying property of gram-positive and gram-negative bacterial cells. It has two forms of release: spray and drops.

This product is suitable for destroying bacteria in the mucous membrane. Its active components are quickly absorbed into tissues and penetrate pathogen cells. It is recommended to use this remedy only with combination therapy, since the spray alone does not eliminate the infectious process.

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Shelf life of drops and spray

The expiration date of the drug is the date indicated on the production packaging, after which the product cannot be used. The release date and expiration date of these drops are usually indicated on the side of the packaging. Failure to comply with them may lead to undesirable consequences.

Read more about storage conditions, expiration dates of medications, and whether expired medications can be used here.

In a closed package

Subject to temperature and light conditions, in closed packaging, Isofra is stored for three years from the date of manufacture . It doesn’t matter whether before opening the bottle or after, the drug must be in the production cardboard box. Otherwise, the drug will deteriorate even before use.

After opening

After opening the bottle, its expiration date does not change and remains the same. You can use it for 36 months.

The main thing is to comply with the storage conditions specified in the instructions. The medicine can be used until the last day of the expiration date. If there are 2-3 days left before the end, you can safely use it for the intended purposes. The drug will not cause any harm to your health.

But some precautions must be taken. After the first use of the spray, you need to close it with a special screw cap. In order to avoid germs getting onto the tip, and then into the nasal cavity. And be sure to place the medicine in its original packaging after each use.

After the drug runs out, the empty bottle must be disposed of immediately.

The shelf life of this drug depends primarily on maintaining the temperature during storage. And also on the light conditions of the place in which it is stored. Otherwise, the effectiveness of the drops will decrease and sediment may appear at the bottom of the bottle.

Storing the spray in the refrigerator will not in any way affect its shelf life.

Storage conditions

When storing the drug, the room temperature should not exceed 25 degrees. It is advisable to store in a dry, dark place. The drug cannot be frozen or heat treated. It is also not recommended to expose the bottle to direct sunlight and spray near an open fire.

Storing the drug in open form is strictly prohibited.

At the pharmacy

In pharmacies, drops are stored in industrial sealed packaging. As a rule, they are placed on display or in special cabinets, racks, shelves where light does not penetrate. Medicines in the pharmacy are stored in separate cabinets, in accordance with the type of dosage form. Their physicochemical and hazardous properties, pharmacological and toxicological effects are taken into account.

"Isofra": reviews

For children, the instructions allow the use of the product from 2.5 years. The drug should be used strictly as prescribed by a doctor. This medicine saved many children from a persistent runny nose, when thick green snot flowed for several weeks. Even the most persistent rhinitis goes away two days after starting to use Isofra spray (reviews).

For children, Komarovsky recommends using other drugs, although he sees nothing wrong with using this particular spray. According to the doctor, the drug is not a systemic antibiotic and is not addictive. Komarovsky himself never prescribes this spray, as he considers the drug insufficiently effective and poorly studied.

Some people find the bottle impractical and very awkward to hold in an upright position. They also note a non-functional dispenser for the drug “Isofra” - reviews for children say that the stream flows unevenly from it.

There are parents who used Isofra spray to treat runny noses in children, but it did not bring any results. Negative reviews are usually associated with the use of the drug without a doctor’s prescription. In this case, it was used to treat allergic sinusitis or rhinitis. There have been cases when even the doctor’s recommendations did not help the medicine cope with the disease.

Adults note how effective Isofra is for sinusitis; reviews repeatedly confirm this. A positive point is that when treating with such a drug, you don’t have to take antibiotics or do injections, since the spray itself copes with harmful bacteria. Full recovery occurs already on the fifth day of using the drug.

Advice from Dr. Komarovsky

Dr. Komarovsky is a practicing pediatrician, and few parents have not heard of him. He has his own children's clinic, and in his free time he conducts research into infectious childhood diseases.

The pediatrician also paid attention to the topic of runny nose in children. According to him, there are no children who would not encounter this disease. He advises not to treat a runny nose, but to relieve the symptoms. In his opinion, snot is nothing more than the body’s reaction to pathogenic viruses, and along with the mucus that the nose generously produces, those bacteria that successfully fight infection are also released.

When the nasal sinuses are treated, pathogenic microbes freely penetrate into the body, provoking a more serious course of the disease. Therefore, Komarovsky advises keeping the child’s nasal mucosa moist in case of a runny nose. In addition, it is recommended to ensure that the temperature in the nursery is no higher than 21 ° C, and the air humidity varies within 75%.

Based on his many years of experience working with children, the doctor gives the following recommendations for diseases of the upper respiratory tract:

• Humidify the air in the room where the child sleeps.
• Every 2-3 hours, irrigate your nose with saline solution or a composition consisting of sea salt dissolved in 250 ml of water.
• Use the drug “Ectericide” to treat a runny nose, which has emollient and antiseptic properties.
• For children under 3 years of age, the doctor recommends lubricating the nose with oil enriched with vitamin complexes A and E.
• You cannot treat a runny nose in children with vasoconstrictor drugs, for example, Naphthyzin, Xelen and others. They alleviate the patient's condition only temporarily and can cause swelling of the nasopharynx.

Only a doctor should decide on the use of this or that drug in the treatment of a particular disease. You should always remember that there are no harmless medications, even for topical use. Isofra spray may be useful only in the prescribed dose and subject to a certain period of treatment. You should never self-medicate, as the consequences of such actions are often sad.