Spray Nicorette. Instructions for use, results of use, reviews from smokers and doctors

Nicorette spray release form

The unique and practical form makes the drug one of the most popular among well-known brands. Dosed use helps to use the product for its intended purpose at any time. Absorption of active substances occurs through the mucous membrane of the oral cavity, which ensures instant elimination of the desire to take up a cigarette.

The spray is available in the form of a convenient bottle, which is small in size.

The stylish and compact shape allows you to always have it with you. Nicorette is a nicotine-containing drug used as replacement therapy. Rapid delivery of the necessary chemicals allows you to relieve withdrawal symptoms in a short time. In difficult situations, relief occurs in virtually seconds.

Storage conditions, price and analogues

The drug is dispensed from pharmacies without a prescription. The spray is stored at a temperature of no more than +25 degrees. Shelf life: 3 years. The price of Nicorette spray is from 980 to 1120 rubles.

Analogues of the drug based on the active substance include:

• Nicotinell;
• Nikquitin.

They also contain nicotine and can be used for replacement treatment during the first time of quitting tobacco. Nicotinell is more expensive, about 2500 rubles, and Nikvitin is cheaper, from 350 to 700 rubles.

Analogues of the drug for therapeutic action are:

• Champix tablets;
• Gamibazin tablets or chewing gum;
• Spray Nicoin;
• Ticizin;
• Lobesil;
• Nikvitin;
• Brisantine;
• Tabex.

However, these drugs can only relieve the symptoms of tobacco withdrawal syndrome and promote a psychological attitude towards quitting smoking. They do not contain nicotine.

Patients often ask which drug to choose when quitting smoking - Tabex or Nicorette . What's better? This question cannot be answered unambiguously. These two drugs have a similar mechanism of action, but the active substance is different. While Nikrorette contains purified nicotine, the healing component of Tabex is the alkaloid cytisine.

This substance is extracted from the broom plant and has an effect similar to nicotine. Tabex is also used for replacement therapy when quitting smoking. This product has earned a lot of positive reviews. But before choosing a drug, you should consult your doctor. Both Tabex and Nicorette have contraindications that only a physician can take into account.

Pharmacological properties

After using 1 dose, nicotine is distributed throughout the body within 4-6 seconds. First of all, it reaches the brain. Pharmacokinetic nicotine is an active substance that is quickly absorbed through the mucous membrane.

Metabolism of the drug occurs primarily in the liver. Oxidation and demethylation of cytochrome P450 is observed. As a result, cotonine is formed as the main metabolite. It is a marker of smoking. Other metabolites are less active and their number is minimal.

Compound

The main active ingredient of the drug "Nicorette" is medical nicotine, which serves as a substitute for that found in cigarettes. Therefore, physical dependence is significantly weakened. The drug also contains substances that cause aversion to cigarettes. Ingredients:

• nicotine 12 mg;
• levomenthol 1 mg;
• propylene glycol;
• ethanol;
• poloxamer;
• distilled water;
• trometamol

Operating principle

This component affects acetylcholine receptors. When it is used in therapeutic doses, its action increases the release of neurotransmitters. This has a direct effect on the functioning of the heart and the entire circulatory system, and also changes the metabolic process in the body.

Reviews from smokers describe Nicorette spray only on the positive side. This is largely due to the lack of significant changes in mental status. The process of formation of adrenaline, dopamine, norepinephrine and serotonin activates the central nervous system, improves mood, increases physical activity, and most importantly affects the pleasure center in the cerebral cortex.

But this is all only in small doses. With a large amount of nicotine entering the body, depression of the central nervous system occurs. This occurs against the background of desensitization or decreased sensitivity of receptors. In addition, neuromuscular transmission is stimulated, which quite sharply turns into depression after a short period of time.

After application within 20 minutes. Up to 90% of the released active substance is concentrated in the blood.

Systematic use of the spray allows you to control a constant volume of nicotine, which helps to significantly reduce withdrawal symptoms. The half-life is approximately 2 hours. Then, within 12-15 hours, the rest of the chemical compounds are released through the kidneys in the form of cotinine and unchanged substance.

Positive reviews

It is recommended to familiarize yourself with consumer opinions in advance before purchasing a product such as Nicorette spray. Reviews indicate the following advantages of the product:

• after using the spray, the craving for smoking actually decreases, although not for long (at first, the relief lasts no longer than half an hour);
• The spray comes with detailed instructions, which contain detailed information about both the product itself and the features of its use;
• the bottle is characterized by its compact size, as well as a convenient, stylish shape;
• The design of the spray mechanism prevents accidental pressing;
• with one injection, much less nicotine enters the body than when smoking one cigarette (at the same time, it is absorbed into the blood faster and eliminated from the body);
• the information on the packaging is printed in a fairly large and legible font;
• the drug is widely available (you can buy it in almost any pharmacy without a doctor’s prescription).

Indications for use

In the past, nicotine was used for a long time to treat colds, malaria, in powder form for fainting conditions, and as an analgesic and stimulant.

Research continues around the world to use it to prevent and treat conditions such as:

• herpes zoster;
• nonspecific ulcerative colitis;
• Alzheimer's and Parkinson's disease;
• herpes;
• attention disorder;

Today this substance is used in drugs to combat smoking. Nicotine replacement therapy helps cope with withdrawal symptoms less painfully. Regardless of the person, this condition always appears, even in the case of temporary or partial cessation of smoking cigarettes.

The main indications of Nicorette spray are:

• getting rid of tobacco addiction in lactating and pregnant women;
• to reduce the number of cigarettes smoked;
• replacing tobacco with a safer product;
• as an alternative to cigarettes if it is impossible or there is no desire to quit smoking;
• with withdrawal syndrome;
• in cases where it is impossible to use a regular cigarette;
• in the treatment of nicotine addiction.

Nicorette spray, according to many reviews from smokers and doctors, significantly reduces the risk of excess weight. The drug helps keep appetite moderate, as there is no withdrawal syndrome.

Negative reviews

Does Nicorette spray help? An exact answer can only be given after using the product yourself, because each body perceives certain drugs differently. However, it would be a good idea to read the negative reviews that say the following:

• at first, when using the product, you often experience a strong sore throat, as well as dizziness;
• in case of strong nicotine addiction, the spray is used often, and therefore one bottle lasts about a week (in this case, the use of the product turns out to be quite expensive);
• the strong menthol aroma is not at all pleasant; on the contrary, it greatly irritates the receptors;
• irritating the esophagus, the drug causes severe and frequent nausea, which goes away after discontinuation of the drug;
• nicotine spray performs a replacement rather than a therapeutic function, because final smoking cessation occurs extremely rarely;
• Even if you do not inhale during injection, there is a high probability of the product getting into your throat.

Contraindications

The drug with medical nicotine is quite safe and suitable for almost everyone who wants to get rid of a bad habit. However, it should be remembered that if you have had serious health problems in the past or currently have chronic diseases, you must consult a doctor before using Nicorette.

Do not use the spray under the following conditions:

• pathologies of the cardiovascular system (angina pectoris, myocardial infarction, severe arrhythmia);
• disruptions in the functioning of the kidneys and liver;
• disruption of the endocrine system (diabetes mellitus);
• problems with the gastrointestinal tract (esophagitis, peptic ulcer);
• benign and malignant formations;
• postoperative period (depending on the volume of surgical intervention);
• severe infections, including those of the oral cavity;
• dental implantation;
• intolerance to individual components of the product.

Smokers' reviews of Nicorette spray characterize it from the best side. Experts indicate the high effectiveness and safety of the drug even during pregnancy. But despite this, there is a risk of a negative impact on the unborn child. The ideal option is to quit the bad habit on your own during pregnancy and as quickly as possible.

Nicorette products: what to choose?

A fairly new product on the market is Nicorette spray. Reviews note a number of other products produced under this brand. So, you can also find nicotine patches and tablets. Based on the experience of using different forms of Nicorette, consumers highlight the following main advantages of the spray:

• the spray is an ideal solution for those with skin that is overly sensitive or prone to irritation (the use of patches can cause redness and rash);
• spray is the most acceptable form of nicotine use during pregnancy;
• spray and patch are the most convenient forms of taking nicotine for those who are not going to say goodbye to smoking, but the unpleasant smell of tobacco is unacceptable in certain situations (business events, a date, a flight, a medical facility, etc.);
• tablets and patches, unlike sprays, do not allow for a sudden cessation of nicotine, as they have a cumulative effect (which is why a spray is recommended for people with problems with the cardiovascular system);
• the only situation in which the spray is inferior to the patch is problems with the respiratory system and gastrointestinal tract (also in this case, tablets are not recommended).

Instructions for use, dosage

Using the device is quite simple.

There are some points that must be observed:

1. Refill the container. Place the spray nozzle as close to the oral cavity as possible.
2. Press once to spray liquid. It is important not to breathe at this moment and try not to get the stream on the mucous membranes of the lips and throat.
3. Do not swallow saliva for about 30-40 seconds. This time is enough for the active substance to be well absorbed to achieve the desired result. It is important not to take food or various liquids for 20-30 minutes.

If a new bottle is used, it must be tested first. To do this, it is enough to spray into the air 2-3 times. When small splashes appear, this means that the device is ready for use. The same manipulation should be carried out if the use of the balloon is interrupted for more than 2 days.

As for the dosage, there are some nuances, namely:

1. One therapeutic dose is one injection. Often this is not enough for a heavy smoker to overcome the desire to take up a cigarette. Therefore, a single use of 2 doses is allowed. Typically, the interval between injections is from 30 to 60 minutes. This is enough for most tobacco addicts.
2. Up to 4 therapeutic doses are allowed within an hour. The interval can be 30 minutes or 15 minutes, when one injection is given. Additional use of the product is regulated by subjective sensations and the desire to smoke a cigarette.
3. No more than 64 doses are allowed per day. Excessive intake of medical nicotine into the body can negatively affect the well-being of even a healthy adult.

Nicorette spray (reviews from smokers claim that the positive effect largely depends on the correct use of the drug) is suitable for those who have decided to say goodbye to the bad habit.

The full course of treatment is 2-3 months. During this period, an additional incentive to quit cigarettes can be a consultation with a psychologist and the comprehensive support of others. It is important to give yourself instructions about the need to quit smoking.

What is the dosage of the drug? And how to use it?

How does Nicorette spray work? First of all, it saturates the body with a certain amount of nicotine, but this amount represents a minimum value. As soon as a person has a strong desire to smoke, he needs to use a spray. The solution must be sprayed in the mouth. The instructions for using Nicorette spray say that if a person still has a desire to smoke after use, he must repeat the procedure. Nicorette spray instructions for use are located in each box of the drug, that is, a person has the opportunity to clearly study the method of use. You can study a detailed paragraph on the correct use of the spray.

If a smoker smokes quite a lot, he has the opportunity to take a double dose. Nicorette spray acts on the body very carefully and consistently, so you should not use it too much.

According to statistics, patients use about one or two doses every hour. It should be remembered that Nicorette helps to quit smoking, but you should not take more than four doses in one hour, as it can cause side effects from the drug. In no case should you use the spray more than 64 doses per day.

Side effects

Unpleasant symptoms can actually appear when using any medications. Nicorette spray is no exception. However, all manifestations are mainly associated with the so-called withdrawal syndrome.

Since smoking is a bad habit, dependence on which is formed at the psychological and physiological level, its withdrawal will always be accompanied by side effects.

This is mainly expressed as follows:

• Bad mood;
• insomnia;
• nervousness;
• constant worries and remorse over little things;
• change in heart rate;
• violation of attentiveness and patience;
• dizziness;
• obsessive persistent cough;
• constipation;
• sudden bleeding of the gums.

Such manifestations gradually stop. Some ailments remain until the end of the therapeutic course.

Possible side effects include the following:

• nausea;
• belching;
• frequent headaches;
• hiccups;
• irritation of the mucous membranes of the oral cavity and upper respiratory tract;
• change in taste sensations;
• burning in the red border of the lips and directly in the oral cavity;
• the appearance of stomatitis;
• profuse sweating;
• disturbance of consciousness;
• loose stools;
• salivation;
• stomach pain;
• sore throat.

Confusion, severe irritation of the mucous membranes, constant nausea and intermittent vomiting indicate the need to immediately consult a doctor. The drug contains a small amount of ethanol.

Therefore, motorists should use Nicorette with caution. A rather serious disadvantage of the drug is that with prolonged use it is addictive. Of course, such addiction is less dangerous than regular cigarettes. To make withdrawal painless, you should gradually reduce the daily therapeutic dose.

How to use the product

After purchasing a new Nicorette spray, you need to spray it into the air the first couple of times. The same procedure should be repeated if you have not resorted to medication for 2-3 days. How to use the medicine correctly:

1. Apply the spray to your mouth.
2. Press the dispenser button.
3. Make sure that the spray does not get on your lips or throat.
4. Hold your breath while injecting to avoid getting into your lungs.
5. Do not swallow saliva for 15-20 seconds.
6. Refrain from water and food after consumption for 15-20 minutes.

The drug should be used at approximately the same time as smoking a cigarette, or in case of a sharp, unbearable desire to take a drag.

Overdose

Excess intake of nicotine into the body is very dangerous for humans. In certain cases it is even life threatening. The dangerous dose is 50-60 mg.

The manifestation of poisoning consists of the following symptoms:

• severe headache;
• nausea and persistent vomiting;
• digestive disorders;
• pain in the epigastric region;
• unexplained weakness;
• changes on the part of the visual analyzer;
• uncharacteristic sweating.

If such manifestations occur, you should immediately stop smoking cigarettes and using the spray. Be sure to be in the fresh air, take activated carbon, and drink hot drinks. Good rest and sleep is required. If there is a sudden change in cardiac activity and breathing, cardiopulmonary resuscitation is required.

While taking Nicorette, it is not recommended to drink alcoholic beverages. This can provoke additional intoxication of the body, which in turn will lead to additional side effects. Typically, a person who has taken alcohol has less control not only of his behavior, but also of his desires. As a result, you want to smoke a cigarette and in a drunken stupor they do it very often.

Severe nicotine poisoning is manifested by symptoms such as:

• weakened pulse;
• convulsions;
• respiratory and cardiac dysfunction;
• loss of consciousness;
• changes in the perception of taste and smell.

You should be vigilant about storing the drug in the house if you have small children. They tend to put things in their mouths. It is necessary to ensure that the child does not accidentally become poisoned. A certain dose for an adult is safe enough. At the same time, it can be fatal to a child.

Overdose is mainly associated with combination with other similar drugs. In addition, problems may also arise in individuals who have consumed a small amount of cigarettes in a short period of time.

Interaction

It is known that many medications must be taken separately. When combined with other medications, an allergic reaction or lack of therapeutic effect may occur first. Severe complications appear, the treatment process is delayed, and sometimes new forms of the disease even form.

Nicorette spray is described by smokers in a positive way, but it is capable of increasing blood pressure for a short time. Pains similar to angina pectoris and increased heart rate appear, as reported. This is especially noticeable if the product was used with other medications.

According to research, it has also been found that nicotine can enhance the effects of adenosine, which in turn leads to the above symptoms.

The dosage of drugs such as Clozapine, Ropinirole, Tacrine, Theophylline, Pentazocine should be reduced. During the period of quitting smoking, this should be at least 6 months. The spray somewhat reduces the rate of elimination of these drugs, which will inexorably lead to an overdose. During the period of quitting cigarettes, a slight increase in plasma levels is observed.

This is not related to treatment with these medications, but is a specific reaction of the body to giving up a bad habit. Women who take hormonal contraceptives should be examined by a cardiologist and gynecologist. It is necessary to eliminate possible risks of combining 2 drugs.

Special recommendations would be the following:

1. Combination with alcohol. Doing this according to the instructions and recommendations of doctors is strictly unacceptable. Alcoholic drinks lead to decreased sorption of nicotine in the oral cavity. In addition, the risk of severe side effects increases. Only small doses of alcohol containing a minimum percentage of alcohol are allowed. It should be remembered that the combination of two components such as nicotine and ethanol can lead to increased side symptoms of intoxication and negatively affect overall well-being during the period of sobering up.
2. Therapy in childhood. Treatment with medical nicotine for persons under 18 years of age is contraindicated. However, in some situations everything is decided individually under medical supervision. Currently, there is no evidence of the use of Nicorette in childhood. There is also no information about possible risks in this population.
3. Pregnancy and lactation. When a woman is pregnant, smoking has a very negative impact not only on her health, but also on the unborn child. The spray in this case causes less harm. This was established by studying breast milk, which contained significantly less nicotine than regular cigarettes. An important point is the absence of the child’s passive smoking factor. In any case, it is necessary to get rid of a bad habit and Nicorette is only an alternative, and not a safe substitute for cigarettes.

Use of the drug Nicorette

Adults, including elderly patients Depending on the severity of the craving for smoking, chewing gum with different concentrations of the active substance can be used. Usually it is enough to use 8-12 chewing gums per day. For persistent smokers (Fagerstrom nicotine dependence test score 6 or those who smoke 20 cigarettes per day) or patients who are unable to quit smoking with Nicorette 2 mg chewing gum, it is recommended to start with the dosage form at a dose of 4 mg. Other patients should begin treatment with the 2 mg dosage form. You should not use 24 chewing gums per day. In case of complete smoking cessation, Nicorette is used for at least 3 months. Then you should gradually reduce the amount of chewing gum. The use of the drug should be stopped when the daily consumption of gum decreases to 1-2 pads. If smoking cessation is carried out gradually by reducing the number of cigarettes smoked, then gum should be chewed between smoking episodes, as soon as an irresistible urge to smoke appears, in order to increase the intervals between smoking episodes as much as possible and thus reduce daily cigarette consumption. If a reduction in the number of cigarettes smoked is not achieved within 6 weeks, treatment strategies should be reviewed. An attempt to quit smoking should be made only when the patient feels ready for this, but no later than 6 months after the start of treatment. If significant smoking cessation is not achieved within 9 months after the start of treatment, the treatment regimen should be reconsidered. As a rule, it is not recommended to use Nicorette mint flavor for 12 months. However, some patients may need long-term treatment to prevent a return to smoking or previous levels of tobacco use. If you suddenly feel the urge to smoke again, you should use several Nicorette gum. Consulting a psychologist in most cases helps to achieve success. Most smokers may experience weight gain after quitting. Nicorette gum can help control this process, which is dose-dependent. Taking 8 to 12 Nicorette gummies in the appropriate dosage form may help control weight gain after quitting smoking. Temporary withdrawal To avoid manifestations of temporary withdrawal, it is recommended to use Nicorette gum during the period when the patient does not smoke, for example in areas where smoking is prohibited or in other situations when the patient is forced not to smoke and there is a sudden desire to smoke.

Spray price in Moscow, St. Petersburg, regions

The cost of drugs is constantly changing. It largely depends on the region and distance from the center. However, the drug can be ordered from the online store regardless of where you live.

Nicorette product (spray): price

Have you ever wondered how much money you spend on cigarettes per week, per month, per year? By simple calculations we can conclude that it is much cheaper to purchase Nicorette (spray). Price may vary depending on region. So, for a bottle of spray designed for 150 injections in Moscow and the region you will have to pay 700-1300 rubles. In the Northern capital, the price of the drug reaches 1,150 rubles. In the Urals, “Nicorette” can be purchased for 800-900 rubles. In the northern regions, the price of the product reaches 1,250 rubles, and in the center and south of Russia - 1,000 rubles. As for Ukraine, the spray costs about 300 UAH there.

Reviews from smokers about the drug

If a bad habit has been formed over the years, you should always have a can of life-saving liquid with you. The craving for a cigarette goes away quickly, after 3 months you don’t want to smoke at all. Regular injections also help cope with emotional problems.

Reviews from smokers confirm positive changes when using Nicorette spray.

You should never put up with a bad habit, even if you have been smoking for decades. Nicorette spray really helps, even if smoking continues for decades, tested in practice. First, the desire decreases, and the consumption of cigarettes reaches 2-3 per day, and then you no longer want to smoke. You just have to want it and everything will work out.

There is an opinion that it is more difficult for women to get rid of many bad habits. This also applies to smoking cigarettes. But modern pharmaceuticals help to quickly get rid of this too. Just a few injections and the craving for a cigarette goes away. Nicorette helps even in the most hopeless situations, when smoking up to 2 packs a day.

What you need to know about nicotine spray?

To get a noticeable effect from Nicorette spray, it is advisable to refrain from smoking cigarettes. This way you will get a psychological result when the drug becomes a replacement for harmful tobacco products. If you continue to smoke cigarettes, you won’t be able to perceive the anti-smoking spray as a cure, which means you won’t be able to quit smoking either.

The psychological attitude is extremely important, it is what allows you to quit smoking in most cases, and anti-smoking medications are an auxiliary element.

Experts recommend giving up cigarettes no later than six months after using Nicorette spray if you want to reduce the number of cigarettes. You should not use Nicorette dosed topical spray for longer than 9 months without visible results. If you have problems, you should consult a doctor to adjust your treatment for nicotine addiction. For safety reasons, the bottle with the drug must be kept closed. This is convenient for transportation and frequent use. The product should be kept away from children and not allowed to come into contact with eyes. The closing mechanism is quite simple to use. To close the bottle, you need to press the button down firmly and then lower the dispenser.

Experts note that the anti-smoking spray format is convenient to use and its effect occurs faster, since absorption occurs through the mucous membranes. Cigarettes work in a similar way, delivering substances through mucous membranes and through smoke. The compactness of Nicorette allows you to use it at any time of the day, in any situation. It does not require water or special conditions. You can quit smoking in any environment, this helps you cope with your addiction faster.

Reviews from specialists and doctors

There is an opinion that they produce anti-smoking sprays of 2 types. Some discourage the craving for smoking due to the unpleasant smell in the mouth, others simply replace cigarettes. Actually this is not true. All drugs of this type contain replacement nicotine and pleasant flavors. Nicorette spray has the same qualities.

Its effectiveness is due to the correct selection of dosage and percentage of the active substance.

Quitting a habit is quite difficult. Nicorette spray is not a product that will help 100%. An independent attitude is also important. The drug significantly reduces withdrawal symptoms. The craving for smoking does not go away immediately and forever; this requires several days of taking the drug.

If a person smoked rarely and for a short time, then 1 dose per hour is enough. With proper therapy, you can completely overcome the desire to smoke within 3 weeks, and after 3 months the spray is used extremely rarely. Smoking always causes bad breath. To cope with it you need to completely give up cigarettes.

Nicorette has a pleasant minty taste, so your breath always remains fresh. In addition, tobacco smoke and its derivatives are known to negatively affect enamel. The spray significantly reduces the desire to take up a cigarette, and teeth noticeably brighten after 3-4 weeks, even on their own.

Very often people complain about Nicorette spray that it has an incomprehensible burning property. However, after just a few injections this goes away. According to reviews from smokers, such sensations usually appear in people with high sensitivity of the oral mucosa and gums. Therefore, they should simultaneously use sensitive toothpastes and seek advice from a dentist.

How to use the spray?

Every time you feel the need to smoke a cigarette, you need to spray the spray; to do this, press the bottle’s special dispenser once. If after using the product you still experience a strong desire to smoke, then take a second dose of Nicorette after 10-15 minutes. You should be guided by your feelings; if one press is not enough for you, then do two in a row at once. The main thing is that you are not drawn to cigarettes after this. The method of application is simple.

Some rules of use:

1. Spray a dosed spray for topical use, bringing the device as close to the mouth as possible so that all the drops hit the mucous membrane.
2. Press the bottle sharply and quickly so that the full dose of the substance comes out.
3. The spray should not come into contact with the lips and the back wall of the larynx.
4. When spraying, try not to talk or breathe so that the substances do not enter your respiratory tract.
5. Do not re-use less than 15 minutes after the first.

If you are actively quitting smoking, you will need to take 1 or 2 doses of Nicorette every hour. It is forbidden to use the drug more than 4 times in one hour. The daily maximum dosage is 128 presses. An analogue of this drug can be used in a different way.

Nicorette spray can be used to completely quit cigarettes and to reduce their daily amount. For a gradual transition, you can replace every second cigarette with a spray. The substances contained in the drug alleviate withdrawal symptoms, making it easier to tolerate nicotine withdrawal. The drug can be used for as long as needed, if necessary. However, experts do not recommend using the product for longer than a year. It is advisable to gradually reduce the amount of use of the drug in order to subsequently abandon it in order to quit smoking.