Comfoderm cream - how it will help the skin with diseases!

Photo: eapteka.ru

Photo: eapteka.ru

Photo: akrikhin.ru

Photo: akrikhin.ru

KOMFODERM is a synthetic steroid for topical use. Belongs to the group of corticosteroids for the treatment of skin diseases for external use - highly active corticosteroids, group III (D07AC14) and corticosteroids in combination with other drugs (D07XC). Active ingredient: Methylprednisolone aceponate (COMFODERMA M2 additionally contains Urea).

You need to know that the half-life is about 16 hours. The drug COMFODERM is available without a doctor's prescription!

Release form, composition and packaging

In the pharmacy you can find the names Comfoderm K, Comfoderm M, Comfoderm M2. The drug is produced in the form of a cream and ointment in two versions. They differ from each other in the composition of auxiliary components and duration of validity. Comfoderm M2, in addition to the main substance, additionally contains urea, which restores water balance and moisturizes the skin.

The cream has a uniform white consistency with a slight specific odor. Absorbs quickly and spreads well over the skin. Begins to act in 5 minutes. Packaged in aluminum tubes of 15 g each, placed in cardboard packaging. Comfoderm ointment has a thicker consistency, the product is packaged in tubes of 15 g, 30 g. It differs from the cream in the exposure time - it remains on the surface of the skin longer, the effect lasts up to 8 hours.

The active component of Comfoderm is a substance from the group of corticosteroids - methylprednisolone aceponate. It is a synthetic hormone with a pronounced anti-inflammatory, keratolytic effect. Among the auxiliary components are liquid paraffin, petroleum jelly, beeswax, and castor bean seed oil.

Comfoderm ointment and cream - the difference

The drug Comfoderm is available in two forms: cream and ointment. Both contain the same active ingredient. To understand the difference between ointment and Comfoderm cream, you need to pay attention to the additional components of the drugs and their consistency:

1. Cream is a form of medicine based on water and oils. This ensures easy and quick absorption. At the same time, the components of the cream are unable to penetrate into deep layers; they can be applied to wet surfaces.
2. Ointment – ​​contains fats and paraffins. The absorption of the drug occurs more slowly, but the effect is long lasting. The components are able to penetrate into the deep layers of the dermis. The ointment can only be used to treat dry skin; it is not suitable for treating weeping skin.

pharmachologic effect

When applied externally, Comfoderm cream has an anti-inflammatory, soothing, anti-allergic, and anti-exudative effect. The active substance acts in several directions at once:

• Suppresses the functions of leukocytes and macrophages, which helps stop inflammatory processes.
• Reduces capillary permeability, thereby eliminating redness.
• Prevents the release of histamine, stops the allergic reaction.
• Suppresses the synthesis of prostaglandins, which leads to a decrease in pain.
• Auxiliary components provide favorable conditions for the restoration of the epidermis, restore water balance, moisturize, and increase local immunity.

Comfoderm cream has the following effects:

• eliminates redness;
• stops inflammation;
• relieves pain;
• removes itching, burning;
• calms, relieves irritation;
• fights swelling;
• resists the spread of allergies to other areas of the epidermis;
• prevents complications, infections, and oozing.

When used correctly, the therapeutic effect is achieved within a few days.

Pharmacokinetics

After distributing the product onto the skin, the active components are absorbed and concentrated in pathological areas. The drug begins to act within 5 minutes, you can feel the therapeutic effect almost immediately - itching, burning, pain, and a feeling of tightness are eliminated. Rapid absorption is ensured by the light consistency of the drug. There are no greasy spots, shine, or sticky feeling left on the skin.

Partially active components penetrate into the general bloodstream. It is broken down by the liver and excreted by the kidneys. The half-life lasts 16 hours. The concentration of glucocorticosteroid in the blood increases in the presence of open wounds on the surface of the skin, when applied to large areas of the epidermis.

Comfoderm ointment – ​​hormonal or not?

When encountering a drug for the first time, patients rush to study its composition. The main goal is to find out whether Comfoderm is hormonal or not. The drug contains methylprednisolone aceponate. It is a non-halogenated steroid, similar in structure to hormonal compounds that are synthesized by the body.

Thus, Comfoderm ointment is a hormonal drug. This limits the duration of use of the ointment. In addition, not all patients are allowed to take hormonal medications, so be sure to consult a specialist before use. When applying Comfoderm ointment to the skin, suppression of inflammatory and allergic reactions, a decrease in proliferation reactions is observed, which suppresses common symptoms of inflammation (ointment and Comfoderm):

• erythema;
• swelling;
• erythema;
• irritation;
• pain;
• itching

Indications

Comfoderm cream is prescribed for dermatological diseases of the skin associated with inflammation and an allergic reaction.

• Microbial eczema;
• Atopic dermatitis;
• True eczema;
• Neurodermatitis;
• Childhood eczema;
• Contact dermatitis;
• Occupational eczema;
• Simple contact dermatitis.

The drug is prescribed if:

• itching;
• burning;
• feelings of tightness;
• rashes;
• redness;
• swelling;
• weeping eczema.

Used for eczema and dermatitis of various origins.

Which is better: COMFODERM or AKRIDERM

ACREEDERM cream.
Photo: aptekabm.ru The drugs are not analogues of each other. Active ingredient COMFODERMA: Methylprednisolone propionate. COMFODERM M2 cream additionally contains Urea. The active components of ACRIDERM are Betamethasone dipropionate (present in the entire line), Gentamicin sulfate (ACRIDERM GENTA), Clotrimazole and Gentamicin (ACRIDERM GK), Salicylic acid (ACRIDERM SK). Release form: ointment and cream. Indications for AKRIDERM:

• allergic skin diseases (including acute, subacute and chronic contact dermatitis, occupational dermatitis, solar dermatitis, neurodermatitis, pruritus, dyshidrotic dermatitis);
• acute and chronic forms of non-allergic dermatitis;
• psoriasis.

Indications for ACRIDERM GENTA

• dermatitis (simple and allergic), especially secondary infections;
• eczema (atopic, childhood, coin-shaped);
• atopic dermatitis (diffuse neurodermatitis);
• simple chronic lichen (neurodermatitis limited);
• solar dermatitis;
• exfoliative dermatitis;
• radiation dermatitis;
• diaper rash;
• psoriasis;
• itching

Indications ACRIDERM GK

• simple and allergic dermatitis (especially complicated by secondary infection);
• diffuse neurodermatitis (including atopic dermatitis);
• limited neurodermatitis (including simple chronic lichen);
• eczema;
• dermatomycosis (dermatophytosis, candidiasis, lichen versicolor), especially when localized in the groin area and large folds of the skin.

Indications for ACRIDERMA SK

• psoriasis;
• atopic dermatitis (neurodermatitis);
• lichen planus;
• eczema;
• dishydratic dermatitis;
• ichthyosis and ichthyosoform changes.

COMFODERM is approved for use from 4 months. AKRIDERM is indicated for children from 2 years of age (with caution). Medicines are dispensed without a doctor's prescription!

Both drugs are produced in Russia. AKRIDERM is cheaper in cost than COMFODERM.

Use during pregnancy and breastfeeding

The active components of the cream partially penetrate into the general bloodstream, which increases the likelihood of side effects and a negative impact on the development of the fetus. In this regard, the use of the product during pregnancy is permitted in special cases when the desired result is much higher than the expected risk. Apply a thin layer once a day, do not use occlusive dressings, it is recommended to mix with baby cream to reduce the dosage. The course of therapy should not exceed 4 weeks. If there are any undesirable manifestations, you should inform your doctor and stop therapy.

The active ingredients can pass into breast milk, so use by nursing mothers is prohibited. If there is an urgent need for therapy, the child is temporarily transferred to artificial feeding and the milk is expressed.

Comfoderm ointment - what does it help with?

Having found Comfoderm ointment on the prescription sheet, not all patients understand why it is needed and for what purpose it is prescribed. The drug has many indications for use, so why it should be used in a particular case is determined by the doctor. According to the instructions for the drug, it can quickly suppress inflammatory and allergic processes, reducing unpleasant symptoms. Considering these properties of Comfoderm ointment, the instructions recommend its use for the following types of diseases:

• eczema (microbial, true);
• occupational dermatitis;
• contact dermatitis;
• allergic dermatitis;
• dyshidrotic eczema.

Allergy ointment Comfoderm

Skin allergic reactions occur suddenly. Contact with aggressive chemical compounds in laundry detergents and the use of low-quality hygiene products in most cases are the cause of such dermatoses. Patients pay attention to the appearance of rashes, redness of the skin, cracks, and peeling. All this is often accompanied by swelling, hyperemia, itching and burning. To cope with all this, dermatologists recommend using Comfoderm for allergies.

The drug is applied in a thin layer, evenly distributed over the affected area of ​​the skin. The ointment is slowly absorbed, so you need to wait a little to achieve the desired therapeutic effect. The application procedure is performed once a day, the duration of use is indicated by the doctor individually. In parallel, it is necessary to take antihistamines to stop the allergic reaction, and not just its manifestations.

Comfoderm acne ointment

The appearance of acne on the skin is accompanied by many unpleasant sensations. Swelling, swelling in the areas of rashes, pain and burning cause a lot of inconvenience. They do not last long, until the pimple opens. To combat such unpleasant sensations, dermatologists advise using Comfoderm for acne.

Apply the ointment to the affected areas with clean hands. Distribute the product with light massaging movements, lightly rubbing. After this, it is forbidden to wash the treatment area for 30–40 minutes. It is better not to expose the elements to hygiene products at all throughout the entire period of therapy.

Comfoderm for eczema

Talking about the cases in which the remedy can be used, for which Comfoderm ointment helps, dermatologists also highlight eczema among skin diseases. Pathology usually refers to pathological foci of inflammation of the skin, manifested in the form of redness and pink spots. With their appearance, patients note a number of pathological symptoms, including:

• itching;
• burning;
• peeling of the skin;
• increased skin dryness.

To combat such appearances on the skin, doctors prescribe Comfoderm ointment. A small amount of the drug is applied directly to the lesions of the skin. The procedure is carried out 1-2 times a day, strictly following the doctor’s instructions. The duration of therapy is determined individually. The maximum period of use of Comfoderm ointment is 3 months (ointment and Comfoderm).

Comfoderm for psoriasis

The disease is characterized by a chronic inflammatory process affecting the skin and skin appendages. In severe cases, internal organs and systems are involved in the pathological process (psoriatic arthritis). Patients are more concerned about the skin manifestations of the disease: papules of different sizes, which tend to merge into large plaques. Over time, the pink-red lesions become covered with small silvery scales.

Immediately at this time, the skin becomes hyperemic, swollen, and very itchy. To save the patient from such unpleasant manifestations of the disease, doctors prescribe Comfoderm for psoriasis. The ointment is applied directly to the resulting lesions and plaques. 1-2 treatment procedures are carried out per day. The drug is used during periods of exacerbation of the disease.

Comfoderm for herpes

Comfoderm can be used for herpes only as a symptomatic remedy. The drug does not contain antiviral components, therefore it is unable to influence the cause of the disease. However, the ointment helps to quickly get rid of the manifestations of the disease, a rash in the form of blisters that are very itchy and cause a burning sensation.

To speed up the healing process and make you feel better, dermatologists recommend using Comfoderm. The drug relieves itching, reduces swelling, and helps the rapid healing of erosive surfaces that form after the vesicles open. The ointment is applied once a day, with clean hands. Treatment lasts 3–5 days, after which the symptoms of herpes disappear.

Comfoderm for lichen

In dermatology, ringworm is an infectious-allergic disease that manifests itself as an exanthema. There are many varieties of this type of pathology. In this case, Comfoderm ointment is used for pityriasis rosea. The mechanism of development of dermatosis has not yet been established, and there is no single version regarding the likely method of infection. Dermatologists suggest that the causative agent is herpes types 6 and 7.

Pityriasis rosea is a pink spot, the diameter of which reaches 2–5 cm (maternal plaque). Along the periphery of the spot, the skin begins to peel off. When peeling, a spot forms with a pronounced bright red border. To quickly eliminate it and remove the inflammatory process on the skin, use Comfoderm ointment. A small amount of it is applied directly to the lesion 1-2 times a day, as a result of which it decreases in size and disappears faster.

Comfoderm for burns

In order to speed up the healing process, to relieve inflammation and its symptoms, the use of Comfoderm ointment may be indicated as prescribed by a doctor. The product reduces hyperemia, reduces swelling, which promotes rapid healing and epithelization of the damaged surface. A small amount of ointment is applied to the damaged area. Only one procedure is required per day. The duration of treatment is determined by the volume of affected skin areas.

Comfoderm for eyes

Allergic reactions often affect the organ of vision. Redness of the conjunctiva, swelling of the eyelids, itching and burning cause severe discomfort. In the absence of proper therapy, which is based on the use of antihistamines, vision may deteriorate. To get rid of the symptoms of the disease and eliminate discomfort, Comfoderm is used as part of complex therapy: for what and how - the doctor determines in a particular case.

A small amount of ointment is applied to the eyelid area. No more than one use of the drug is allowed per day. The duration of treatment is determined by the doctor. Doctors do not use hormonal drugs for long-term treatment of eye pathologies. Otherwise, the risk of developing glaucoma increases.

Use in children

The cream should not be used by children under 4 months of age. Apply the drug in a thin layer to the affected areas only once a day. It is advisable to carry out the procedure in the evening after bathing the baby. To reduce the concentration of the active component, mix the drug with baby cream.

The treatment regimen is as follows:

• In case of severe manifestations of allergies in the first days, use the cream undiluted.
• After approximately 3 days of active therapy, the external symptoms of an allergic reaction disappear and the skin begins to recover. Comfoderm is mixed with baby cream and therapy is continued for up to 7 days.
• If skin irritation persists, the course of treatment is extended. In other cases, the child’s skin continues to be treated with moisturizing baby cream for several more weeks.

This treatment regimen is extremely important for children under 3 years of age. It also helps to avoid withdrawal syndrome, rapid relapses, and skin atrophy.

Comfoderm cream - instructions for use

The drug Comfoderm is a cream for external use based on glucocorticosteroids, which is recommended for the treatment of skin diseases. Quickly relieves inflammation, improves skin condition with dermatitis and eczema. Eliminates signs of allergies, but has a number of contraindications.

Composition and release form

Comfoderm is a series of medications for the treatment of inflammatory skin diseases. The cream is a homogeneous white mass with an unobtrusive odor and contains 0.1% of the active substance methylprednisolone aceponate. Auxiliary components included:

• phenoxyethanol;
• potassium dihydrogen phosphate;
• hexyldecyl stearate;
• isopropyl myristate;
• purified water;
• cetyl alcohol.

Comfoderm ointment is translucent with a gray tint, additionally strengthened with castor seed oil, paraffin, and the addition of natural beeswax. It has a thicker structure and can leave a filmy feeling on the skin after application.

Comfoderm M2 is a cream from the medicinal series, additionally containing urea, which exfoliates and accelerates healing. It is intended to restore water balance and is prescribed during an exacerbation.

Cream 0.1% is available in small tubes made of soft aluminum, additionally packaged in a cardboard box. Available in 15 g packaging. Comformerm ointment can be purchased in tubes of 15 and 30 g.

Pharmacological properties

The drug is used externally and contains the synthetic hormonal component methylprednisolone aceponate. This active substance is a non-halogenated steroid. When applied externally, it penetrates the site of inflammation, blocks the influx of leukocytes, and reduces the production of the hormone histamine.

The active substance acts on pain receptors and neutralizes proteolytic enzymes. This reduces vascular tone, restores blood flow, and stimulates the removal of excess fluid. This provides Comfoderm cream with the following pharmacological properties:

• painkiller;
• anti-inflammatory;
• tonic;
• antiallergic;
• restorative.

After application, the release of histamine is reduced, which relieves redness, pain and burning. The permeability of blood vessels decreases, excess fluid is quickly eliminated, and nutrition of the inflamed area of ​​the skin improves.

When applied externally, most of the glucocorticosteroid is concentrated in the upper part of the dermis. A small amount is excreted through the sweat glands, after metabolism within 16-24 hours it is administered by the kidneys with waste products. Practically does not accumulate in soft and bone tissues.

Main indications for use

Comfoderm cream helps stop inflammation in skin diseases. It can be used as prescribed by a doctor in the following situations:

• eczema of various types;
• atopic dermatitis in children and adults;
• neurodermatitis;
• occupational eczema;
• contact form of dermatitis;
• psoriasis.

The drug relieves inflammation, burning and itching well, and relieves unpleasant symptoms during exacerbation of childhood eczema. Active substances eliminate skin tightness, remove painful swelling and burning.

The use of Comfoderm cream is indicated to accelerate the healing of skin with weeping eczema, supports nutrition and blood circulation in the upper layers of the dermis. This reduces the release of inflammatory exudate and normalizes the functioning of receptors and capillaries.

Read more Cream and ointment Gistan - instructions for use

Contraindications to Comfoderm treatment

The medicinal cream should not be used if you are intolerant to one of the active ingredients, so as not to provoke an allergy. Comfoderm is not prescribed to children under 4 months of age with atopic or diaper dermatitis. Other contraindications to treatment include:

• chickenpox rash or lichen at the site of application of the drug;
• skin manifestations of tuberculosis or syphilis;
• rosacea;
• acute reaction to the vaccine;
• herpes zoster or herpes in the active stage.

With great caution, Comfoderm cream is prescribed to patients who have hormonal disorders, diseases of the adrenal glands and thyroid gland. Methylprednisolone aceponate can upset the balance and cause a deterioration in the condition.

For children under 4 months, Comfoderm is strictly prohibited. This is due to unstable functioning of the adrenal glands and the formation of hormonal levels. The use of glucocorticosteroids can disrupt the stable growth and development of the child.

The manufacturer does not recommend using Comfoderm cream during pregnancy in any trimester. This is due to the lack of reliable information about complete safety for the formation and development of the embryo. During this period, the drug can be used for a short course and applied to small areas of the skin.

When breastfeeding, the use of Comfoderm cream is contraindicated. In exceptional cases, under the supervision of a doctor, it is used for a course of no more than 5-7 days. The medicine is not applied to the mammary glands, strictly observing the dosage.

Overdose: main symptoms

When Comfoderm cream is applied to large areas of skin, the level of glucocorticosteroid hormones in the blood may increase. But in clinical trials or accidental ingestion of the drug, there were no cases of acute poisoning or negative reactions.

Side effects of Comfoderm cream

When used correctly, negative reactions after treatment with the drug rarely occur. The most common side effects are associated with individual intolerance and the development of an allergic reaction. It manifests itself as follows:

• severe redness of the skin;
• rashes and hives;
• severe itching, burning, tingling;
• the appearance of pigment spots;
• skin atrophy.

Read more Ointment Gioksizon - instructions for use

Similar violations occur when using the cream for more than 4 weeks. In a number of situations, doctors warn about possible systemic problems. They manifest themselves at the site of application or as a general deterioration in health:

• folliculitis;
• perioral dermatitis;
• hypertrichosis;
• erythema;
• painful burning sensation;
• weight jumps.

In rare cases, when exposed to glucocorticosteroids, mood swings, irritability, and poor sleep occur. If symptoms appear, you must stop treatment with Comfoderm and immediately consult a doctor for advice.

Use in children

Basic recommendations from doctors:

• the course of treatment should not exceed 4 weeks;
• the total area of ​​skin to which the cream is applied should not exceed 10%.

An overdose increases the risk of suppressing the child’s body’s production of its own corticosteroids. This may be accompanied by poor appetite, lack of growth dynamics and other unpleasant complications. Therefore, treatment of children is carried out under the strict supervision of a doctor for a course of 7-10 days, after which the hormonal ointment is changed to a safer one with natural ingredients.

special instructions

If the skin is damaged by a bacterial or fungal infection, Comfoderm cream does not give the desired result; it is used only simultaneously with antibiotics and antimycotics. Therefore, it is imperative to undergo an examination by a dermatologist before starting therapy.

During treatment, contact of the cream with the mucous membranes of the eyes should be avoided. Otherwise, irritation, redness and burning may occur. The drug is not used in ophthalmology. It can cause the development of glaucoma and other dangerous complications.

The drug does not affect the patient’s ability to drive a vehicle or perform work that requires concentration. The product is not recommended to be applied under a bandage, so as not to enhance absorption.

special instructions

Comfoderm should be used after consulting a specialist; independent use may cause side effects and may not lead to the desired result. During therapy, you should follow some recommendations.

• Avoid contact of the product with mucous membranes and eyes.
• In the presence of a bacterial infection, local antibiotics and antimicrobial agents should be used in parallel.

• It is recommended to apply the cream before bed in the summer, as you should avoid direct sunlight on the treated areas. You should also cover the affected areas with clothing.
• During therapy you should avoid drinking alcoholic beverages.
• The cream does not affect the mental state or general well-being; you are allowed to perform precision work and drive a car.

It is forbidden to use Comfoderm for more than 3 months for adults, for more than 30 days for children. Otherwise, side effects and frequent relapses develop.

Contraindications for use

The main prohibition against using the cream is the presence of individual intolerance to the components. An allergic reaction manifests itself as an increase in unpleasant symptoms, relapses, and a deterioration in general well-being. To avoid negative consequences, you need to conduct a test first. A small amount of cream is applied under the knee or elbow. Observe the condition of the epidermis and sensations for half an hour. If there is redness, itching, or burning in the treated areas, do not use the drug.

Other contraindications:

• rosacea;
• rosacea;
• juvenile acne;
• children up to 4 months;
• viral lesions of the epidermis;
• syphilis, skin tuberculosis;
• perioral dermatitis;
• open wounds in areas of allergic rashes;
• vaccination.

Before actively using the product, you must carefully study the instructions and become familiar with the contraindications. Neglecting these requirements leads to negative consequences.

Compound

The composition is based on the substance methylprednisolone aceponate.

100 grams of ointment contains 100 mg.

For better absorption of the active component of the drug by tissues, the following is also used in production:

• liquid paraffin;
• petrolatum;
• castor bean seed oil;
• white beeswax.

One of the main advantages of the medicine is its release in different forms ( regular ointment Comfoderm, Comfoderm K, Comfoderm M2 ).

The active component is the same in all cases, but the list of excipients differs.

For the production of the drug Kofmoderm K, the following additives are used:

• ceramides;
• glyceryl monostearate;
• macrogol stearate;
• potassium dihydrogen phosphate;
• propylene glycol;
• cetostearyl alcohol and other substances, including preservatives.

The following substances and chemical compounds enhance the effect of methylprednisolone aceponate in Comfoderm M2 cream:

• urea;
• carbomer interpolymer;
• Vaseline oil/liquid paraffin;
• propylene glycol;
• polysorbate-80;
• methyl parahydroxybenzoate;
• trometamol;
• distilled water.

The usual composition is more suitable for therapy in the subacute period. It can be prescribed to children from 4 months of age.

This is one of the few hormonal drugs approved for use in the first year of infants' life.

Pharmacology

The mechanism of operation of the dermatological agent is to suppress the function of leukocytes and mononuclear phagocytes, which limits the access of leukocytes to the site of inflammation.

The active substance of the medicinal cream stabilizes lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the inflamed area of ​​the skin.

The working principle of methylprednisolone aceponate also includes:

• decrease in capillary permeability;
• suppression of fibroblast activity;
• activation of collagen production.

The chemical compound used by the manufacturer as the main component of the ointment has the following spectrum of action:

• anti-inflammatory;
• antiexudative;
• antiallergic.

Price

Dermatological ointment is sold in pharmacies and is available without a prescription.

An alternative purchase is to order Comfoderma in the online store.

There, the majority of drugs are offered at a better price, and home delivery is possible.

The cost of one tube with a volume of 15 g is 240-280 rubles , 30 g - from 410 rubles .

Indications for use

The medicine is prescribed to eliminate symptoms characteristic of the following diseases:

• types of eczema: microbial/occupational/children/true/dyshidrotic;
• types of dermatitis: atopic/simple contact/allergic;
• neurodermatitis;
• other inflammatory skin diseases.

Comfoderm is recommended as a treatment for acute and subacute inflammations that occur without separation of serous exudate.

The ointment is suitable for eliminating dermatological problems on smooth skin and areas covered with hair.

The active substance is methylprednisolone aceponate, as well as its metabolites do not accumulate in the body. The conversion products are excreted by the kidneys.

Instructions for use

The medicinal ointment should be used in accordance with the recommendations of the attending physician or the rules of the annotation.

The affected area on the skin is treated with a small amount of the product once a day .

The duration of the treatment course is determined individually from 4 days to 2 weeks .

In severe cases, longer treatment is required, but the continuous time of use of the composition should not exceed:

• for children – 28 days;
• for adults – 3 months.

Comfoderm is a self-sufficient remedy; it can be prescribed for monotherapy, but in particularly difficult cases it is used in combination with other medications.

Side effects

1. When testing the drug, rare cases of adverse events were recorded.
2. The main part is due to allergies , so it is important to carefully study the list of constituent substances before starting a treatment course.
3. Other possible manifestations include:

• acne-like skin changes;
• persistent dilation of small vessels of the epidermis;
• skin disease, which is characterized by limited erythema with the formation of papules, papulopustules, etc.;
• depigmentation.

Also, during the procedures, itching or burning, the development of folliculitis, and the formation of a vesicular rash may be felt.

In most cases, unpleasant symptoms resolve spontaneously.

If you experience a deterioration in your health or worsening side effects, it is recommended to consult your doctor.

Restrictions on use

The dermatological product is not prescribed for the following contraindications:

• tuberculosis, syphilis with manifestations in the focal zone;
• viral infections;
• perioral dermatitis;
• a chronic skin disease that affects the vascular network of the face;
• manifestations after vaccination.

The annotation also indicates the age threshold. You can use the medicinal ointment from 4 months of age.

• When prescribing Comfoderm to an adult patient, the main risk factor inherent in any drug is taken into account - the presence of an allergy to the components of the composition.
• If a pharmacological product is used for the first time, then before starting treatment, testing by applying the cream to the back of the hand.

After rubbing the product into the skin a little, you need to observe the reaction. If redness, swelling, rash or itching appears, you should stop using the medicine.

Pregnancy

1. Women in a delicate situation (pregnancy, lactation) can be prescribed the dermatological product Comfoderm, but subject to short-term use and an understanding of the relationship between potential risks and the expected therapeutic effect.
2. Apply the cream in a thin layer, avoiding the chest and abdomen.
3. These studies conducted when testing the product indicate that the main part of the active substance disintegrates in the layers of the epidermis.
4. If the rules for using the ointment are followed, only a small part of the chemical compound enters the bloodstream, which does not pose a danger to the life of the woman and the fetus.

Precautionary measures

Before using the drug for the first time, you should familiarize yourself with the special instructions for its use:

• When carrying out procedures, avoid contact of the composition with mucous membranes. If necessary, it is recommended to rinse your eyes or mouth thoroughly with plenty of water.
• If the pathology gives complications of a bacterial nature or manifests itself in the form of dermatomycosis, in addition to Comfoderm, the patient is prescribed a comprehensive treatment that involves the use of antimycotic and/or antibacterial drugs.
• When treating the skin in the eye area, you should be careful. Prolonged exposure to the active component of the ointment or exceeding the dosage provokes the development of glaucoma.
• The use of a dermatological product does not require any restrictions regarding interaction with complex mechanisms. After the procedure, the patient can immediately begin performing work duties.

Reviews

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Analogs

• If there is a need to select an analogue, you should seek advice from a specialist.
• Taking into account the degree of complexity of the pathology and associated health problems, the doctor will make a new appointment.
• Among the effective substitutes:

• Silkaren (118 rub.);
• Akriderm (94 rub.);
• Betasalik (345 rub.);
• Candiderm (480 rub.);
• Triakutan (RUB 1,050);
• Rederm (165 rub.).

When choosing a cream for the treatment of skin diseases, it is important to clarify the composition - hormonal or not .

On the one hand, the presence of hormones helps to cope with the problem faster, on the other hand, there is a risk of vasodilation and other side effects.

You can avoid such troubles by following your doctor’s instructions and avoiding using the product without a dermatologist’s prescription.

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Side effects

If you follow the instructions, the product is well tolerated. However, with a long course of therapy for more than 4 weeks, negative consequences appear on the skin:

• striae;
• atrophy;
• color change;
• excessive dryness;
• roughness;
• acne;
• thinning of the epidermis;
• decreased local immunity, relapse;
• itching;
• burning;
• acne.

After prolonged use of the drug, withdrawal syndrome occurs, resulting in a relapse after a few days. The most dangerous side effect is the development of perioral dermatitis, which is very difficult to get rid of.

Exceeding the course of therapy for more than 1 month can lead to systemic side effects:

• headache;
• dizziness;
• nausea;
• weight gain or weight loss;
• menstrual irregularities in women;
• nervousness;
• poor sleep;
• irritability;
• decreased ability to work;
• bitterness in the mouth.

This situation is dangerous for the development of kidney and liver failure, and disruption of the functioning of the gastrointestinal tract.

Analogs

There are a huge number of drugs for the treatment of allergies and dermatitis in pharmacies. As for Comfoderm analogues, there are several of them.

• Comfoderm M and M2. The preparations differ in consistency and set of additional components. It is recommended to use after the disappearance of severe allergic rashes. For the first few days, use Comfoderm cream, then switch to ointment. Prohibited for use by children under 18 years of age. The price for a tube with a capacity of 15 g is within 200 rubles.

• Advantan . Available in several forms - ointment, emulsion, cream. The active component is methylprednisolone aceponate. Indications for use are various eczema and dermatitis. The cream should be applied once a day, mainly in the evening. But experts allow twice the use per day. The maximum course of therapy for adults is 12 weeks, for children – 4. Contraindications and side effects are identical to Comfoderm. The shelf life of the cream is 3 years. Dispensed without a prescription, although the instructions indicate “prescription”. The German-made drug costs 555 rubles. per tube with a capacity of 15 g.

The issue of replacing one drug with another should be discussed with a specialist.

Comfoderm ointment - analogues

A wide range of drugs for topical use makes it easy to choose a Comfoderm substitute. The number of ointments, creams, gels with a hormonal component is large. Depending on the type of pathology, the severity of the clinical picture, the nature and extent of skin changes, dermatologists select the most appropriate medicine in a particular situation. If you need to replace Comfoderm ointment, analogues, cheap medicines often use the following:

• Akriderm;
• Triderm;
• Sinaflan;
• Lokoid;
• Elokom.