Momat cream is a medicinal product that is used to treat skin diseases associated with an allergic reaction. Eliminates painful symptoms, blocks the production of histamine, prevents damage to new areas of skin. It begins to act immediately after application, a lasting therapeutic effect is observed within 10 days. Before use, consultation with a specialist is required.
Pharmacodynamics and pharmacokinetics
When used externally, this drug, due to its active component mometasone , exhibits an anti-inflammatory, antipruritic and anti-exudative effect.
It has been established that absorption of both ointment and cream is very insignificant. After 8 hours from the moment of applying the external agent to an intact skin surface without using an occlusive dressing, about 0.4-0.7% of the active substance enters the systemic bloodstream. Mometasone is metabolized in the liver. The drug is excreted from the body, mainly through the kidneys and a small amount with bile .
Compound
The active component of the drug is a synthetic analogue of glucocorticosteroid – mometasone furoate. An artificially created hormone inhibits the production of histamine, which provokes the development of an allergic reaction. Its effectiveness is several times higher than that of a natural glucocorticosteroid. In 2-3 days it normalizes hormonal balance and eliminates allergy symptoms. Mometasone furoate accelerates the process of restoration of damaged tissues, relieves painful symptoms, eliminates swelling, and reduces the fragility of blood vessels.
Auxiliary components of the cream:
- wax;
- paraffin;
- propylene glycol methyl parahydroxybenzoate;
- alcohol;
- distilled water.
The additional composition is also involved in the restoration of the skin. Creates a protective film on the surface of the epidermis. It resists the negative influence of environmental factors, prevents moisture loss from cells, and creates favorable conditions for rapid renewal of the top layer. Alcohol destroys painful microflora, prevents the spread of infection, and the expansion of allergies.
Contraindications for use
This external remedy is not prescribed for:
- rosacea;
- perioral dermatitis;
- bacterial, viral or fungal infection of the skin;
- tuberculosis, syphilis;
- post-vaccination reactions;
- under 2 years of age - ointment;
- lactation, pregnancy when used for a long time, over large areas and in large quantities;
- high sensitivity to GCS and other components of the drug.
You should also be careful when applying the drug to intertriginous skin and face, using with occlusive dressings, in large quantities or large areas of skin.
Action
Momat cream has an anti-inflammatory, anti-edematous, antipruritic, and wound-healing effect. The active components of the drug accumulate at the site of application, penetrate into the deep layers of the epidermis, and partially enter the general bloodstream.
Within the first 10 minutes after application, it eliminates itching and burning. The next day, the swelling disappears, the spots seem less pronounced. The integrity of the skin is restored gradually. Peeling and redness disappear, wounds heal, and new rashes do not appear.
The average duration of therapy is 10 days, the maximum is 1 month. Extend in case of severe forms of the disease in consultation with a specialist.
With prolonged use of the cream, addiction occurs and the functioning of the adrenal glands is disrupted. Atrophy, thinning of the skin, and discoloration in the areas where the drug is applied are observed. After abrupt withdrawal of the drug, the allergic reaction worsens.
special instructions
When Momat ointment or is applied to large areas of the skin surface for a long time or under a bandage, there is a possibility of developing symptoms of suppression of the functions of the hypothalamic-pituitary-adrenal system or Cushing's syndrome.
Sometimes, due to propylene glycol, which is part of Momat, irritation occurs at the application site. Such cases require discontinuation of the drug and the appointment of appropriate therapy.
It must be remembered that some GCS change the manifestation of a number of skin diseases, which makes diagnosis difficult. Also, such drugs often delay wound healing.
Long-term treatment with Momat and sudden withdrawal can cause the development of rebound syndrome, which is manifested by dermatitis with severe burning and redness of the skin. For this reason, after long-term therapy, drug withdrawal is carried out gradually, for example, in the form of a transition to an intermittent treatment regimen until it is completely stopped.
When using Momat cream or ointment, it is necessary to protect the mucous membrane of the eye from contact with it.
Momat ointment for external application approx. 0.1% 15.0 63638
Description
Momat Glenmark Pharmaceuticals Ltd. (India) ointment for external use 0.1%; aluminum tube 15 g, cardboard pack 1; EAN code: 8904091101719; No. LSR-005532/07, 2007-12-28 from Glenmark Pharmaceuticals Ltd. (India) Latin name Momate Active ingredient Mometasone * (Mometasonum) ATX: D07AC13 Mometasone Pharmacological group Glucocorticosteroid for local use [Glucocorticosteroids] Nosological classification (ICD-10) L20 Atopic dermatitis L21 Seborrheic dermatitis L29 Pruritus L30.9 Dermatitis, unspecified L40 Psoriasis Description of drugs oh form Cream: white colors. Ointment: white. Pharmacological action Pharmacological action - local anti-inflammatory, glucocorticoid, antipruritic. Pharmacodynamics Mometasone is a synthetic corticosteroid with anti-inflammatory, antipruritic and antiexudative effects. GCS induce the release of proteins that inhibit phospholipase A2 and are known collectively as lipocortins, which control the biosynthesis of inflammatory mediators such as PG and LT by inhibiting the release of their common precursor, arachidonic acid. Pharmacokinetics Absorption is negligible. 8 hours after a single application to intact skin (without an occlusive dressing), about 0.4% (cream) and 0.7% (ointment) of the active substance are found in the systemic circulation. Mometasone is intensively metabolized in the liver, excreted mainly by the kidneys and in small amounts with bile. T1/2 is approximately 5.8 hours (ointment). Indications of the drug Momat Cream for external use Inflammatory phenomena and itching in dermatoses amenable to GCS therapy. Ointment for external use Inflammatory phenomena and itching in dermatoses (psoriasis, atopic dermatitis, seborrheic dermatitis) amenable to GCS therapy in adults and children over 2 years of age. Contraindications: hypersensitivity to any component of the drug or corticosteroids; rosacea, perioral dermatitis; bacterial, viral (Herpes simplex, chickenpox, Herpes zoster) or fungal skin infection; tuberculosis, syphilis; post-vaccination reactions; pregnancy (treatment of large areas of skin, long-term treatment); lactation period (use in large doses and/or for a long time); children under 2 years of age (ointment). With caution: application to facial skin and intertriginous skin, use of occlusive dressings, as well as treatment of large areas of skin and/or long-term treatment (especially in children). Use during pregnancy and lactation The safety of mometasone furoate during pregnancy and lactation has not been studied. GCS penetrate the placental barrier. Long-term treatment and the use of large doses during pregnancy should be avoided due to the risk of negative effects on fetal development. GCS are excreted in breast milk. In cases where GCS is intended to be used in large doses and/or for a long time, breastfeeding should be stopped. Side effects Rarely - irritation and dryness of the skin, burning sensation, itching, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, signs of skin atrophy, stretch marks, prickly heat. In less than 1% of cases - the formation of papules and pustules. When using external forms of GCS for a long time and/or to treat large areas of skin, or using occlusive dressings, especially in children and adolescents, side effects characteristic of systemic GCS may occur, including adrenal insufficiency and Cushing's syndrome. Interaction Interaction studies with other drugs have not been conducted. Overdose Symptoms: inhibition of the function of the hypothalamic-pituitary-adrenal system, including secondary adrenal insufficiency. Treatment: symptomatic, if necessary - correction of electrolyte imbalance, discontinuation of the drug (with long-term therapy - gradual withdrawal). Special instructions When applied to large areas of skin for a long time, especially when using occlusive dressings, systemic action of GCS may develop. Given this, patients should be monitored for signs of suppression of the function of the hypothalamic-pituitary-adrenal system and the development of Cushing's syndrome. Avoid contact of Momat with the eyes. Propylene glycol, which is part of the drug, may cause irritation at the site of application. In such cases, use of Momat should be discontinued and appropriate treatment should be prescribed. It should be borne in mind that GCS can change the manifestations of some skin diseases, which can complicate the diagnosis. In addition, the use of GCS may cause a delay in wound healing. With long-term therapy with GCS, sudden cessation of therapy can lead to the development of rebound syndrome, manifested in the form of dermatitis with intense redness of the skin and a burning sensation. Therefore, after a long course of treatment, the drug should be discontinued gradually, for example by switching to an intermittent regimen before stopping treatment completely. Application in pediatrics. Due to the fact that in children the ratio of surface area to body weight is greater than in adults, children are at greater risk of suppressing the function of the hypothalamic-pituitary-adrenal axis and developing Cushing's syndrome when using any topical corticosteroids. Long-term GCS treatment in children can lead to disturbances in their growth and development. Children should receive the minimum dose of the drug sufficient to achieve the effect. Release form Cream for external use, 0.1%. In an aluminum tube with a nozzle with a closed end, with a cap with a piercing point, 5 or 15 g. Each tube is in a cardboard box. Ointment for external use, 0.1%. In an aluminum tube with a nozzle with a closed end, with a cap with a piercing point, 5 or 15 g. Each tube is in a cardboard box. Manufacturer: Glenmark Pharmaceuticals Ltd., India. Name and address of the legal entity in whose name the registration certificate is issued: Glenmark Pharmaceuticals Ltd., India. Consumer complaints should be sent to the address Glenmark Impex LLC: 115114, Moscow, st. Letnikovskaya, 2, building 3, 2nd floor. Tel.: (499) 951-00-00. www.glenmark-pharma.ru Conditions for dispensing from pharmacies By prescription. Storage conditions for the drug Momat: In a dry place, protected from light, at a temperature not exceeding 25 °C. Do not freeze. Keep out of reach of children. The shelf life of the drug Momat is 2 years. Do not use after the expiration date stated on the package. 2000-2015. Register of Medicines of Russia The database is intended for healthcare professionals. Commercial use of materials is not permitted.
Possible product names
- Momat ointment for external application approx. 0.1% 15.0
- MOMATE 0.1% OINTMENT 15.0
- MOMATE 0.1% 15.0 OINTMENT
- MOMAT OINTMENT 15 G. X1
- MOMAT OINTMENT D/NAR. NOTE 0.1% TUBE 15G
- MOMATE 0.1% OINTMENT FOR EXTERNAL APPROX. 15G TUBE (R)
- (Momate) Momate ointment for external use. approx. 0.1% 15.0
Use in pediatrics
Momat ointment is contraindicated for use in children under 2 years of age. It is known that in young patients the ratio of skin surface area to weight is greater than in adults, therefore children are at greater risk of suppressing the functions of the hypothalamic-pituitary-adrenal axis and developing Cushing's syndrome during external use of this drug.
Long-term therapy with Momat often leads to disruption of the development and growth of the child. Therefore, children are prescribed the drug in the minimum dosage sufficient to obtain a positive effect.
Indications
Momat is prescribed for obvious signs of an allergic reaction with eczema, weeping, rash, and redness.
Indications for use are:
- dermatitis of various origins;
- eczema;
- psoriasis;
- lupus;
- lichen;
- insect bites.
Momat cream should not be used if the allergic reaction is accompanied by a secondary infection. Large areas of weeping with bleeding wounds, ulcers, and purulent rashes appeared on the skin. In such cases, external antibiotics are prescribed. In the presence of open wounds, mometasone penetrates faster into the bloodstream and spreads throughout the body, affecting the functioning of internal organs and general condition. A number of side effects occur.
Side effects
When treated with Momat cream or ointment, undesirable symptoms may occur that affect the activity of the endocrine system, for example, adrenal insufficiency or Cushing's syndrome . It is also possible to develop dermatological or allergic reactions in the form of: skin irritation, dry skin, burning, folliculitis, hypertrichosis, acne, perioral dermatitis, and so on.
Use during pregnancy and breastfeeding
The safety of mometasone furoate during pregnancy and lactation (breastfeeding) has not been established.
GCS penetrate the placental barrier. Long-term treatment and the use of large doses during pregnancy should be avoided due to the risk of negative effects on fetal development.
GCS are excreted in breast milk. In cases where GCS is intended to be used in large doses and/or for a long time, breastfeeding should be stopped.
Be sure to read:
Pimafukort ointment and cream: what it helps with, instructions for use, cheaper analogues
Momat's analogs
Level 4 ATC code matches:
Gistan N
Sinalar
Avecourt
Mesoderm
Momederm
Betazon
Silkaren
Elokom
Flucinar
Sinaflan
Celestoderm
Cutivate
Advantan
Betamethasone
Beloderm
Mometasone Furoate
Uniderm
The main analogues of this external remedy are: Asmanex, Mometasone, Elokom and Uniderm.
Reviews about Momat
As a rule, reviews of Momat cream are found on forums where various childhood diseases are discussed. At the same time, many mothers say that they use this remedy in the treatment of childhood diathesis, atopic dermatitis . It is also reported that this cream is often prescribed for very young patients. Although some parents doubt the correctness of the therapy, the effectiveness of this remedy appears in a fairly short time.
In addition, on the Internet you can find many comparisons of this drug with other drugs. However, reviews of Momat ointment show that most patients have made their choice and, if necessary, use this particular product.
Some users are interested in whether this ointment is hormonal or not, since patients often refuse treatment with any hormonal drugs, considering them especially harmful to health.
It should be noted that psoriasis or atopic dermatitis are systemic diseases. Therefore, competent therapy should be aimed not only at suppressing symptoms, but also the condition of the entire organism.
It is not always possible to completely restore the health of such patients, but the general condition can be successfully controlled. Therefore, in addition to using hormonal ointments, like Momat, it is necessary to carry out other procedures that can affect the course of the disease - monitor the diet , avoid allergens , normalize metabolism , etc.
Momat (cream, ointment): instructions for use, price, reviews, indications, analogues
Every first aid kit should have a drug against skin inflammation.
One of these is Momat , which eliminate unpleasant symptoms in the shortest possible time.
We will find out what the advantages of the product are, and we will also find out whether the ointment is hormonal or not.
Price
The ointment is produced by an Indian brand. You can buy it with a doctor's prescription.
The price depends on the release form, region of sale and auxiliary components:
- Momat cream 0.1% – from 163 rubles ;
- Momat ointment, 0.1% – from 230 rubles ;
- Momat-S ointment – from 505 rubles .
Momat can be bought in Moscow at a price of 370-400 rubles.
The drug is produced in an aluminum tube with a volume of 5, 10, 15 g.
Instructions for use
The treating dermatologist should determine the dosage of the cream or ointment.
The doctor calculates the amount of the composition depending on the type of pathology, severity of symptoms, and age of the patient.
Usually the product is applied in a thin layer once before bedtime. It is acceptable to use it under a breathable bandage if we are talking about a small area of skin.
If there is no result after 3-4 days, you need to visit the dermatologist again.
The doctor may replace Momat or increase the dosage. He also prescribes the duration of therapy. Usually it is 5-10 days.
In severe situations, the period increases to 1 month.
No cases of negative interactions with other drugs have been identified. However, doctors do not recommend using Momat immediately after other ointments. It's worth waiting 20-30 minutes.
There is also no point in treating with several creams at once, which are analogues of the adrenal hormone.
Use by pregnant women and during breastfeeding
It is forbidden to apply cream to the skin during pregnancy and lactation.
In rare cases, a specialist prescribes Momat during pregnancy and lactation.
The age limit for the ointment is from 2 years. During therapy, it is important to monitor the results of biochemistry of blood and urinary fluid.
Side effect
A hormonal drug can provoke adverse reactions after penetration into the blood.
Increased concentrations of mometasone can cause disruption of the endocrine system.
Very long-term use of the ointment and its application to large areas of the skin provoke the development of adrenal insufficiency.
Sometimes patients experience local side effects:
- redness and dry skin;
- swelling;
- burning and stinging;
- increased hair growth;
- rash;
- increased itching.
To eliminate the consequences of an overdose, you need to restore the water and electrolyte balance.
If the cream is quickly discontinued , rebound syndrome may occur, in which the symptoms of inflammation significantly intensify and do not go away. Therefore, it is important to gradually reduce the dose of the drug.
To avoid complications, it is recommended to conduct a sensitivity test.
You should not swallow the ointment. Store it out of the reach of children for two years with the tube closed and 1 month after opening.
Momata price, where to buy
In Russian pharmacies, the price of Momat ointment for external use 0.1% is 216-269 rubles. The price of Momat cream for external use 0.1% varies between 171-269 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
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Release form, composition and packaging
Ointment for external use is white.
- Active ingredient: mometasone furoate (1 g - 1 mg)
- Excipients: paraffin (white soft paraffin), white beeswax, propylene glycol monostearate.
White cream for external use.
- Active ingredient: mometasone furoate (1 g - 1 mg)
- Excipients: white soft paraffin, white beeswax, propylene glycol monostearate, stearyl alcohol, cetomacrogol, propylene glycol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water.