Recently, cases of heart attack or stroke due to the formation of blood clots in blood vessels have become more frequent. The risk of premature death due to this problem can be prevented with the help of special medications. Everyone knows that Aspirin has blood thinning properties. There is even a special release form of this drug - “Aspirin Cardio”. But acetylsalicylic acid has a negative effect on the gastrointestinal tract. Therefore, a drug was created in which this property was neutralized - Cardiomagnyl. Reviews of this product note that it combines the effectiveness of acetylsalicylic acid and good tolerability. Therefore, this drug is ideal for preventing complications of cardiovascular diseases.
Properties of acetylsalicylic acid
This substance has long been used in medicine. But its anti-inflammatory and antipyretic effects are mainly known. The drug “Aspirin” has been the most popular remedy for colds and headaches for many years. But recently it has become known that acetylsalicylic acid has blood thinning properties. It has been clinically proven that this substance can be used to prevent blood clots. Moreover, among other similar agents, acetylsalicylic acid is considered the most effective in this regard. This is explained by the fact that this substance can block the production of thromboxane, an enzyme responsible for platelet aggregation. For a healthy person, this substance is necessary, as it regulates the process of blood clotting. But in patients with cardiovascular pathologies, this leads to the formation of blood clots.
But the peculiarity of the main drug with this active ingredient - Aspirin - is that it cannot be used for a long time. Acetylsalicylic acid irritates the gastrointestinal mucosa and can cause inflammation. In addition, in some conditions it provokes bleeding. And with the constant use of Aspirin to prevent blood clots, various side effects often develop. But scientists found a way out. They combined acetylsalicylic acid with magnesium hydroxide in one preparation. This substance neutralizes the negative effects of acid on the gastrointestinal tract and protects against damage to the mucosa.
Overdose
Uncontrolled use of the drug can lead to an overdose. It occurs when 150 mg of acetylsalicylic acid enters the body per 1 kg of weight.
- An overdose can have serious consequences for the patient. His thoughts are confused, coordination of movements and hearing are impaired, and he vomits frequently.
- If urgent measures are not taken, heart failure and shortness of breath manifest. In particularly severe cases, the person may enter a coma.
If there are alarming signs of an overdose, you should not hesitate. It is urgent to give the patient a gastric lavage, give him an adsorbent to drink, and be sure to call an ambulance.
General characteristics of the drug "Cardiomagnyl"
This product was created specifically for the prevention of complications of cardiovascular pathologies. A special composition, including acetylsalicylic acid and magnesium hydroxide, ensures the high effectiveness and safety of the drug "Cardiomagnyl". Reviews from cardiologists and people undergoing this course of treatment confirm this. The drug is very effective for the prevention of thrombosis, thromboembolism and myocardial infarction.
Acetylsalicylic acid is quickly absorbed into the blood and has high bioavailability, so its effect begins after taking the first tablet. And the result lasts for some time after the end of the course of treatment. The drug is often used due to the special properties that acetylsalicylic acid has. It belongs to non-steroidal anti-inflammatory drugs, antiplatelet agents and anticoagulants, reduces temperature and reduces pain.
Drug compatibility
Any aspirin-based medications can harm the body when interacting with other medications. Therefore, at an appointment with a cardiologist, you need to inform about all the medications that are being taken. A negative reaction can be observed when taking Cardiomagnyl simultaneously with various dietary supplements and herbal preparations.
It is not advisable to use acetylsalicylic acid together with non-steroidal anti-inflammatory drugs. Cardiomagnyl increases the effectiveness of insulin and other drugs that regulate blood sugar, and, conversely, reduces the beneficial effects of drugs for gout and blood pressure.
Composition and release form
Doctors' reviews of Cardiomagnyl note that this drug effectively prevents the formation of blood clots, but unlike Aspirin, it causes almost no side effects. This is due to the special composition. The main active ingredient of the drug is acetylsalicylic acid. It suppresses the production of thromboxanes and prostaglandins, providing anticoagulant, anti-inflammatory and analgesic effects. And the absence of side effects from the gastrointestinal tract is explained by the presence of a second active ingredient - magnesium hydroxide. This is an antacid that reduces the acidity of gastric juice. It protects the mucous membrane of the digestive tract from the harmful effects of acetylsalicylic acid, without reducing its effectiveness. In addition, the drug contains excipients that do not affect its action: talc, magnesium stearate, starch, propylene glycol.
"Cardiomagnyl" is produced in tablets. There are two options that differ in the dosage of the active substance - 75 mg and 150 mg. The tablets are packaged in dark glass bottles. Reviews of Cardiomagnyl 75 mg note that its effect is weak, so it is best used to prevent blood clots in mild cases. In case of a more serious condition of the patient, Cardiomagnyl is prescribed as part of a complex treatment at a dosage of 150 mg of the active substance.
Which is better: Cardiomagnyl or Trombital
Medicines thin the blood and improve its rheological properties. The composition of the drugs is identical, the difference lies in the production by a specific pharmacological company and the country of origin.
Cardiomagnyl is a Japanese drug that is produced in Russia, Germany and Denmark. Generic Trombital is a Russian medicine. The product is also available in dosages of 75 and 150 mg. Each package contains 30, 100 tablets.
Attention! There are no marks on Trombital tablets, which makes it difficult to divide them into two parts.
Medicines have similar effects and benefits. Cardiomagnyl and Trombital are used to treat and prevent diseases of the heart and blood vessels. The harm is represented by the side effects of acetylsalicylic acid. When taken for a long time, the active substance irritates the mucous membranes of the stomach, causing ulcers. The benefits of magnesium included in the composition include protection against this. However, medications are not prescribed for exacerbations of gastritis or ulcers.
Trombital and Cardiomagnyl have the same indications:
- hypertension;
- high cholesterol concentration;
- excess weight;
- elderly age.
The benefits of the drugs are ensured due to the absence of sugars in the composition. This allows their use in patients with a history of diabetes mellitus.
Medicines vary significantly in price. Buying a generic will cost 30-40% less than the original.
Indications for use of the drug "Cardiomagnyl"
Judging by the name of the drug, it should be used in the treatment of heart pathologies. But this assumption is refuted by doctors and instructions for use. Reviews from cardiologists about Cardiomagnyl note that it is effective for preventing complications of such pathologies. It is prescribed mainly to those patients who have a high risk of blood clots. If the patient does not have a predisposition to this process, the use of Cardiomagnyl is not advisable. Reviews from doctors note that it is best to prescribe it in the following cases:
- after heart surgery, for example, coronary bypass surgery;
- patients with diabetes or obesity;
- To old people;
- in the complex treatment of hypertension, angina pectoris, acute heart failure;
- with coronary heart disease;
- after myocardial infarction;
- people with bad habits.
How to take the medicine
The doctor prescribes the dose of the drug individually after examining the patient. The instructions indicate the dosage that is prescribed in most cases.
To prevent a heart attack, in case of severe obesity, diabetes, smoking and the risk of blood clots, on the first day you need to take 1 tablet of medication containing 150 mg of salicylic acid. The next day and throughout the course, the dose should be reduced and taken 1 tablet (75 mg) per day.
Features of application
This drug is dispensed from pharmacies without a doctor's prescription. Sometimes patients purchase it on the advice of friends, but before taking it they inattentively study the instructions for use. Reviews of Cardiomagnyl show that some people are mistaken about its properties. Therefore, they leave negative feedback, calling it ineffective. This happens because such patients consider it a drug for the treatment of cardiovascular diseases. It is used for angina pectoris, hypertension, arrhythmia and does not obtain the expected effect. In fact, Cardiomagnyl is a remedy that only prevents complications from such pathologies. It cannot replace cardioprotectors, diuretics or vasodilators. In addition, it is not a source of magnesium, although it contains this substance.
Contraindications to its use
Even when a doctor prescribes a drug, it is advisable to carefully study its instructions. Reviews of Cardiomagnyl note that it is well tolerated, but not all patients can take it. There are certain contraindications, in the presence of which the drug will not help, but, on the contrary, will worsen the patient’s condition. First of all, this is a blood clotting disorder and a tendency to bleed. The cause of this condition may be hemorrhagic diathesis, lack of vitamin K or potassium, or the presence of a stomach ulcer. This is due to the ability of acetylsalicylic acid to thin the blood. In addition, this substance can provoke bronchospasm, so patients with bronchial asthma should not take Cardiomagnyl either.
Reviews from doctors note that there are several other categories of patients to whom this drug is not prescribed:
- children under 18 years of age;
- pregnant women, especially in the 1st and 3rd trimester;
- women during lactation;
- people with kidney failure;
- patients with intolerance to acetylsalicylic acid;
- people with gout;
- patients with cerebral hemorrhage.
Possible side effects
Reviews of Cardiomagnyl note that, unlike Aspirin, it has fewer side effects. They are much less common and less pronounced. Basically, the negative properties of the drug appear when it is taken without taking into account contraindications or when the dosage prescribed by the doctor is not followed. The following side effects may occur:
- heartburn, nausea or vomiting;
- damage to the gastric mucosa, pain and discomfort;
- formation of ulcers on the gastrointestinal mucosa and in the oral cavity;
- bleeding in the digestive tract;
- allergic reactions, from urticaria to bronchospasm;
- tinnitus, dizziness;
- sleep disturbance;
- headache.
Instructions for use "Cardiomagnyl"
This drug can only be used as prescribed by a doctor. In this case, it is necessary to strictly follow its instructions and instructions. Reviews of Cardiomagnyl note that if all recommendations are followed, the drug is well tolerated and begins to act quickly. People like the fact that this product is easy to use. You only need to take the tablet in the prescribed dosage once a day. It is best to do this in the evening, after the last meal. You can swallow the tablet whole or crush it. Then you need to drink the medicine with water. Cardiomagnyl is not a drug for one-time use; it is taken in courses. The duration of treatment is determined by the doctor. Moreover, in some cases it can be very long-term, up to lifelong use of the drug.
Drug interactions
Due to the characteristics of the main active ingredients of the drug, care must be taken when choosing agents for complex treatment. It is advisable that this be done by a doctor, since Cardiomagnyl is not compatible with all medications. The most important thing is not to take it together with other thrombolytics and anticoagulants. This increases the blood thinning effect, which can lead to bleeding. Cardiomagnyl is also incompatible with Methotrexate; this must be taken into account when choosing treatment.
For patients with diabetes mellitus, dosage adjustment of hypoglycemic drugs and insulin is necessary, since acetylsalicylic acid has a slight hypoglycemic effect. There are also drugs that reduce the effectiveness of Cardiomagnyl. This is Ibuprofen, which is incompatible with acetylsalicylic acid, and glucocorticoids. In addition, the absorption of the drug slows down when taking antacids.
Is it possible to use Cardiomagnyl during pregnancy and breastfeeding?
One of the contraindications to regular use of the drug is pregnancy in the first and third trimester. This is due to the harm that acetylsalicylic acid can cause.
The use of Cardiomagnyl in the first trimester can cause irreversible developmental disorders of the fetus. Significant doses of the drug provoke bleeding during childbirth. The risk of intracranial hemorrhage in a child cannot be excluded.
Taking the drug in the second trimester is possible. However, the doctor must evaluate the benefits and possible harm.
The active ingredients of Cardiomagnyl pass into breast milk. Regular use of the medication during lactation is prohibited.
special instructions
Despite the fact that this drug is considered non-toxic and is taken to prevent complications of cardiovascular diseases, it should not be used without the recommendation of a doctor. Do not exceed the recommended dosage, as this increases the risk of bleeding and damage to the mucous membrane of the digestive tract. It should also be taken into account that during the course of treatment with Cardiomagnyl you should not take alcoholic beverages and certain medications. And due to the possibility of side effects from the nervous system, it is not advisable to undergo such treatment if you need to operate a car or other dangerous mechanisms. Therefore, before taking this drug, you should definitely read the instructions for use.
Analogues of "Cardiomagnyl"
Reviews of the use of acetylsalicylic acid for the prevention of thrombosis note that this substance works best. Based on it, several drugs have been created for use for this purpose. These are “Aspirin Cardio”, “Akard”, “Reocard”, “Ekolin”, “Trombo ACC”, “Acecardol” and others. But these analogues of Cardiomagnyl receive not only positive reviews, as they more often cause side effects. Therefore, it is not advisable to replace the drug prescribed by the doctor with them.
There are also analogues of the drug that do not contain acetylsalicylic acid. They have the same effect as Cardiomagnyl, but are based on other active ingredients. This could be Clopidogrel, Trental, Pradaxa, Curantil, Trombopol. They also prevent the formation of blood clots, so if you are intolerant to Cardiomagnyl, it is better to use its analogues.
Compatibility of Cardiomagnyl with other drugs
Cardiomagnyl may enhance the effect of certain medications when used together. Experts name the following drugs that are affected by taking Cardiomagnyl:
- Methotrexate. Reduced renal clearance, destruction of bonds with proteins.
- Heparin and indirect anticoagulants. Platelets change their functioning. Anticoagulants are forced out of their bonds with proteins.
- Antiplatelet and hypoglycemic agents – ticlopidine.
- Preparations containing ethanol.
- Insulin and hypoglycemic drugs.
- Digoxin. There is a reduction in renal excretion.
- Valproic acid. Displacing it from bonds with proteins.
Cardiomagnyl suppresses the action of:
- uricosuric agents;
- antacids and cholestyramine.
Attention! The benefits of Cardiomagnyl are reduced when taken together with Ibuprofen.
"Cardiomagnyl": reviews
The instructions for the drug note that this is an effective remedy used to prevent complications of cardiovascular pathologies. Patients who use it as prescribed by a doctor leave positive reviews as they notice an improvement in their condition. But some people try to treat angina or heart failure with Cardiomagnyl, and, not noticing positive changes, speak negatively about the drug. Although in most cases this remedy is the most effective and safe medicine for the prevention of thrombosis.
