Indications for use
The action of the active components of Lipostabil is aimed at reducing the concentration of lipoproteins in the blood, normalizing lipid metabolism, improving the functional state of the liver, slowing the progression of atherosclerosis, and improving microcirculation.
Lipostabil, according to the instructions, is prescribed for the treatment of:
- Atherosclerosis of blood vessels in the brain, heart, limbs;
- Hyperlipoproteinemia;
- Endarteritis;
- Angiopathy, especially developing against the background of diabetes mellitus;
- Angina pectoris;
- Nephrotic syndrome.
Also, the use of Lipostabil is effective in conditions after cerebral stroke and myocardial infarction, for the prevention of thromboembolism before surgery, treatment and prevention of fat embolism.
Properties and composition
The drug can be purchased in the form of an injection solution and capsules. The active substance of the drug is unsaturated fatty acids. Additional elements included:
- potassium monophosphate;
- pyridoxine hydrochloride;
- a nicotinic acid;
- theophylline.
The injection solution is produced in ampoules, and capsules are produced in cardboard and blister packs. The drug has hypolipidemic and antiatherosclerotic effects.
It neutralizes pathological processes and normalizes the amount of lipoproteins in the blood, accelerating the process of removing cholesterol from the body, which is involved in the development of atherosclerosis. Active components that are metabolized in the liver are excreted in the bile in the form of bile acids.
Directions for use and dosage
Lipostabil, according to the instructions, should be taken 2 capsules three times a day. The duration of the treatment course is at least 3 months. It is recommended to take the medication before meals.
If intensive therapy is necessary, Lipostabil is prescribed intravenously in a slow stream once a day. Daily dosage – 10-20 ml. The duration of use of the medicine is 2-4 weeks. Additionally, oral administration of the medication is indicated. After the condition improves, the injections are canceled, and the capsules should be continued for at least three more months.
In case of fat embolism, until the condition improves, 20-30 ml of Lipostabil are administered intravenously 3-4 times a day.
Price of the medicine and how to buy it:
You can only buy it if you have a prescription from a leading specialist. The estimated price of one package varies from 5,000 to 6,000 thousand rubles, depending on the packaging and form of release.
On our website you can buy Lipostabil from the manufacturer at the best possible price. You can also buy high-quality medicines from us, the prices of which are lower than from other suppliers. The price of Lipostabil on our website depends on the release form and dosage.
The price for the drug Lipostabil is determined by the factory. We are ready to offer the most favorable terms of cooperation both in Russia and the CIS. The price can be greatly reduced.
Features of the use of the drug
If you have been prescribed lipostat, the instructions for use must correspond to the individual regimen drawn up by the doctor. After all, at different stages of the disease you will need a precisely calculated dosage of the drug. For example, in the initial stages of hypercholesterolemia, patients are prescribed no more than 20 mg of the active substance per day.
In this case, the tablets should be taken an hour before meals, consumed with food, or the time elapsed after dinner should not be taken into account at all, because the effectiveness of lipostat does not depend on food intake. In case of liver failure, treatment should begin with 10 mg of the active substance per day
In addition, the prescription of lipostat to elderly people is carried out with extreme caution. They are not recommended to take a daily dosage of more than 20 mg
For very high cholesterol levels, doctors prescribe lipostat at a dose of 40 mg. This dosage is necessary for patients with cholesterol levels of 300 mg/dl.
After administration, the drug quickly enters the bloodstream and accumulates in it in maximum quantities within 1-1.5 hours. Its special concentration is observed in the ileum and liver - places with a high level of fat synthesis. Then lipostat begins to be gradually eliminated from the body. Most of it (70%) exits through the gastrointestinal tract. The kidneys are responsible for removing another 20% of the active substance.
Drug analogues and prices
First of all, let's look at what analogues of Lescol Forte are there. We selected all the medications listed below according to the ATC drug classification system.
The active ingredient of the drug is fluvastatin. All selected analogues correspond to the fourth level ATS codes, despite the composition, which may differ in some medicines, according to indications and methods.
At the moment, there are about 70 analogues on the market - let's look at some of them:
- Atoris - from 195 to 1200 rubles;
- Vasilip - from 136 to 785 rubles;
- Crestor - from 347 to 19,400 rubles;
- Liprimar - from 200 to 2800 rubles;
- Torvacard - from 237 to 1500 rubles;
- Livazo - from 455 to 1440 rubles;
- Rosart - from 370 to 2400 rubles;
- Astin - from 87 to 220 rubles;
- Atorvastatin-Teva - from 93 to 597 rubles.
- The average price of Lescol Forte is 2800 rubles.
Conditions for dispensing from pharmacies
Dispensed by prescription.
Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!
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special instructions
Immediately before using the solution, you should make sure that the contents of the ampoule have a transparent structure; if it is cloudy, the solution is unsuitable for use. When Lipostabil is administered simultaneously with additional agents, only sucrose can be used as a solvent.
Lipostabil is suitable for long-term treatment, as it is characterized by excellent tolerability.
The drug is not contraindicated during pregnancy, during the lactation period, or in pediatric patients, but strict medical supervision is required.
If the patient’s general condition worsens or allergic reactions occur, it is necessary to discontinue drug therapy and select an analogue of Lipostabil for treatment.
Analogues of the drug
The drug Lipostabil has a large number of substitutes. Its analogues are the following:
- Lipostat;
- Essentiale forte N;
- Lipoford;
- Holetar;
- Linseed oil.
Lipostat is an effective medicine containing the active substance pravastatin. The medication is produced in the form of tablets of 10, 20, 40 mg. The dosage is selected individually by the cardiologist and depends on the patient’s condition. The drug is taken one hour before meals. If liver function is impaired, treatment begins with a dose of 10 mg. The maximum concentration in the blood is observed one hour after administration. The active component is excreted from the body through the gastrointestinal tract and kidneys.
Essentiale forte N contains phospholipids. Their chemical structure corresponds to the endogenous type. These elements are able to integrate into damaged hepatocyte membranes and restore the integrity of liver cells. The drug regulates the production of lipoproteins, transports cholesterol and neutral fats to the site of oxidation.
The medication normalizes the process of metabolism of proteins and lipids, has a detoxifying effect on the liver, restores and preserves the cellular structure of enzyme systems and the liver.
Lipoford is a drug that belongs to the statin group. Its active ingredient is atorvastatin. The component reduces the level of cholesterol and lipoproteins in the blood. The effect of treatment can be noticed after 2 weeks. The active ingredient of the drug Choletar is lovastatin. It is not completely and rather slowly absorbed from the gastrointestinal tract.
When taken on an empty stomach, absorption decreases several times. The maximum concentration is observed within 3 hours. The drug is able to penetrate the placental barrier, its active metabolism occurs in the liver. The substance is excreted through the intestines.
Lipostabil capsules 300 mg No. 50
Description
- Manufacturer: Mcm Klosterfrau GmbH, Germany
- Active ingredient: combination of active components of essential phospholipids and etophylline
- Release form: capsules All forms
The action of Lipostabil capsules is aimed at reducing the number of lipids and stabilizing the amount of lipoproteins in the blood plasma.
The drug affects the state of cholesterol that accumulates on the walls of blood vessels, and subsequently removes it along with bile, accelerates the restoration of blood vessels and improves blood characteristics (viscosity).
The medicine is used to treat damage to large vessels of the heart, brain, and limbs with cholesterol deposition in the walls of blood vessels and to prevent blockage of blood vessels by a blood clot.
The composition and effect of the active substances of Lipostabil are described in the instructions. Essential phospholipids contained in capsules restore the structure of cellular and intracellular membranes, improve the metabolism of lipids and proteins in the human body and stabilize the number of lipoproteins in the blood.
Another active component, Theophylline, accelerates blood flow in the vessels of the heart and dilates them.
Most often, doctors prescribe to buy Lipostabil in a pharmacy for the treatment of atherosclerosis (damage to large vessels of the heart, brain, limbs with cholesterol deposition in the walls of the vessel), circulatory disorders, angina pectoris (attacks of pain in the heart due to poor blood supply), and also after a heart attack (acute heart disease), stroke (impairment of blood flow in the brain) and for the prevention of thromboembolism (blockage of a blood vessel by a blood clot detached from the vessel wall). Side effects when taking capsules may include severe allergic reactions and increased sensitivity. They appear within one or two hours after taking the drug, less often - within 24 hours. Contraindications for use are: hypersensitivity to the components of the product and allergy to them. During pregnancy and lactation, capsules should not be used.
In most cases, the use of Lipostabil is prescribed by a doctor in the dosage: 2 capsules approximately 20 minutes before eating (breakfast, lunch and dinner). The drug should be taken with a small amount of water. You can drink no more than 6 capsules per day. The average duration of treatment is 3 months.
Instructions
Capsules, 50 pieces per pack.
pharmachologic effect
Lipostabil belongs to the group of hypolipidemic (reducing lipid levels in the blood) drugs. Improves lipoprotein levels in the blood.
Due to the fact that the ability of high-density lipoproteins (HDL), enriched with polyunsaturated phosphatidylcholine, to take up cholesterol increases, most of the atherogenic (promoting the development of atherosclerosis) cholesterol passes into a state in which it can be more easily transported by HDL, metabolized in the liver and excreted from the body with bile in the form of bile acids. Reduces elevated levels of lipids in the blood. Ensures the mobilization of cholesterol and its removal from arterial walls. Improves the rheological properties of blood.
Indications for use
Hyperlipoproteinemia (increased levels of lipoproteins in the blood), cholesterolemia (increased levels of triglycerides in the blood) and hypertriglyceridemia (increased levels of triglycerides in the blood), atherosclerosis, disorders of the coronary (heart), cerebral (cerebral) and peripheral circulation, angina pectoris, condition after myocardial infarction and stroke, vascular disease, especially in diabetes mellitus, prevention of thromboembolism (blockage of a vessel with a blood clot) before surgery.
Directions for use and dosage
2 capsules of lipostabil (do not chew!) are used 3 times a day before meals with a small amount of water. In many cases of hyperlipoproteinemia, depending on the severity of the condition, long-term treatment is recommended.
Storage conditions
Lipostabil is kept in a place inaccessible to children, sufficiently dark, cool and dry, at storage temperature:
- capsule form - up to 25°C;
- in ampoules - 2-8 °C.
Shelf life, adhering to the storage requirements specified in the instructions:
- capsule form - 3 years;
- in ampoules – 3 years.
In the pharmacy chain, Lipostabil is sold upon presentation of a doctor's prescription.
Lipostabil: instructions for use of capsules
Latin name: Lipostabil ATC code: - Active ingredient: essential phospholipids Manufacturer: MCM Klosterfrau Vertriebsgesellschaft (Germany), Rhone-Poulenc Rorer (France) Dispensed from the pharmacy: without a prescription (caps.), with a prescription (solution)
Storage conditions: caps. – at temperatures up to 25°C, solution d/in. – at 2-8° C
Shelf life: 3 years
Lipostabil is a multicomponent agent for oral and parenteral use with hypolipidemic and antisclerotic effects.
Composition, dosage forms
Lipostabil is available in the form of oral capsules and injection solution.
components:
- In 1 capsule: 300 g of essential phospholipids, 50 mg of theophylline
- In 1 ml of solution: 50 mg of essential lipids, 2 mg of nicotinic acid and AMP, 4 mg of pyridoxine hydrochloride.
Capsules are dark brown elongated pills, packaged in blisters of 10 pieces. Solution for injections - 5 or 10 ml in light-protective glass ampoules with a line and a break point marked on the surface. Ampoules are placed in a transparent plastic tray, 5 pieces each. In the box along with instructions - 5 ampoules or 50 capsules.
Medicinal properties
Features of the use of Lipostabil are determined by the properties of its active component - essential phospholipids. A substance of natural origin, it contains a large amount of polyunsaturated fatty acids, primarily linoleic (almost 70%) and oleic acids.
Thanks to this, the drug normalizes the concentration of lipoproteins, lowers high lipid levels, regulates cholesterol and ensures its removal from the vascular walls.
As a result of the use of Lipostabil, patients' blood condition improves and the threat of atherosclerotic complications is reduced.
Side effects and overdose
The drug is generally well tolerated by most patients. In rare cases, it can cause disorders of the digestive system, and when using high dosages, diarrhea.
Allergic reactions in people with a high sensitivity threshold are also possible. Unfavorable conditions are manifested by skin rashes, itching, urticaria and other typical conditions for such reactions.
If the medicine is used in the form of injections, then if administered incorrectly, there may be redness, induration, and soreness in the injection area.
No specific manifestations of intoxication are observed. The use of high dosages may provoke increased adverse reactions. To relieve an overdose, you need to use traditional cleansing measures: washing, taking activated carbon. If necessary, symptomatic therapy may be required.
Lipantil
Lab. Fournier (France)
Price: 200 mg (30 caps.) – 926 rub.
Medicines with micronized fenofibrate, a fibric acid derivative. Shows hypolipidemic qualities: reduces the content of triglycides and cholesterol in the blood, helps increase HDL. Able to reduce glucose levels to some extent in diabetics.
The mechanism of action is not fully understood. It is assumed that the compound destroys the synthesis of fatty acids and cholesterol in the body and promotes an increase in the number of LDL receptors in the liver.
The drug is prescribed to improve the condition of various forms of hyperlipoproteinemia that cannot be corrected by diet.
Pros:
- An effective remedy
- Regulates cholesterol.
Flaws:
Tribestan
Sopharma (Bulgaria)
Price: tab. p/obol. 250 mg (60 tablets) – 1820 rubles, (180 tablets) – 4484 rubles.
Herbal remedy with hypolipidemic effect. The therapeutic effect is provided by a dry extract of the herb Tribulus creeping.
Due to the high content of furostanol type saponins, the medicine has a positive effect on the general condition of the body.
In addition, the action of the herbal remedy has a good effect on the reproductive system: in men it stimulates the process of spermatogenesis, increasing the number of sperm and their activity, and increases erection time.
The drug is prescribed for the treatment of sexual impotence, male infertility, and also to lower the concentration of total cholesterol.
It is suggested to drink 1-3 capsules. three times a day. The duration of treatment is at least three months.
Pros:
- Natural remedy
- Improves libido.
Flaws:
- Long-term therapy
- High price.
