Mezapam is a drug (tablets) that belongs to the pharmacological group of psycholeptics. Important features of the drug from the instructions for use:
How to dissolve vascular plaques, normalize blood circulation, blood pressure and forget the way to the pharmacy
- Sold only with a doctor's prescription
- During pregnancy: contraindicated
- When breastfeeding: contraindicated
- In childhood: contraindicated
- For liver dysfunction: contraindicated
- If renal function is impaired: contraindicated
- In old age: with caution
Pharmacodynamics and pharmacokinetics
The active ingredient is medazepam. The drug has antiepileptic, anxiolytic and muscle relaxant effects. The active component belongs to the group of benzodiazepines. The instructions for use of Mezapam contain an indication of a weakly expressed thymoleptic effect of the medication.
Medazepam interacts with benzodiazepine receptors of the activating formation of the brain stem (ascending division) and the limbic system. The drug eliminates psychoneurotic tension, anxiety, stress, increased fussiness, and motor agitation.
The medication stabilizes the functioning of the autonomic nervous system, restores emotional balance and an adequate assessment of one’s own illness. Typical benzodiazepine tranquilizers have the most pronounced hypnotic, sedative and muscle relaxant effects.
Contraindications
- Drug and alcohol addiction;
- Sleep apnea syndrome;
- Myasthenia gravis;
- Angle-closure glaucoma;
- Diseases of the kidneys and liver (in acute cases);
- Renal and/or liver failure (in severe cases);
- First trimester of pregnancy and lactation period;
- Hypersensitivity to the components of the drug, as well as to other benzodiazepines.
In the II-III trimesters of pregnancy, the use of Mezapam is possible in cases where the benefit of therapy is higher than the expected harm to the health of the fetus (use of the drug in high doses or for a long time must be avoided).
Side effects
Digestive tract: increased bilirubin, ALT, AST, dyspeptic disorders, dry mouth.
Nervous system: stupor, headaches, accommodation paresis, dizziness, loss of strength, ataxia, confusion, aggressiveness, loss of orientation, dysarthria, depression, anterograde amnesia, disinhibition.
Cardiovascular system: drop in blood pressure, rapid heartbeat.
Respiratory system: in patients with COPD, when treated with high doses, alveolar hypoventilation is recorded; With brain damage and airway obstruction, depression of the respiratory center is noted.
Overdose
Mezapam tablets are taken strictly according to the regimen developed by the doctor in the specified dosage.
If the amount of active substance is exceeded, signs of poisoning may appear.
In case of convulsions, depressed breathing, ataxia, muscle hypotonia and other characteristic symptoms, measures should be taken to urgently remove toxins from the body.
To do this you need to do the following:
- rinse the stomach;
- take any sorbent, laxative;
- measure blood pressure, body temperature;
- monitor heart rate.
Mezapam, instructions for use (Method and dosage)
Tablets are taken 2-3 times a day, starting with a minimum dosage of 5 mg; gradually the amount of medication is adjusted to 30 mg/day. In rare cases, 40 mg of medazepam per day is allowed. For outpatient treatment, the following regimen is recommended: 5 mg in the morning and at 12:66, 10 mg in the evening. In hospital treatment conditions, the maximum daily dose can be increased to 60-70 mg. The duration of treatment is no more than 60 days. After a month, you can repeat the course.
Price
You can purchase Mezapam if you have a prescription sheet certified by the seal of a medical institution and the attending physician.
The cost of one package is 850-1380 rubles .
You can buy a tranquilizer in Moscow in the chain of pharmacies Rigla, ANSImed, Zhivinka, etc. The psychotropic drug is almost always available in the online pharmacy.
Interaction
Increased interaction is observed during treatment with antidepressants, hypnotics, barbiturates, central muscle relaxants, medications for general anesthesia, narcotic analgesics, and when taking alcohol. The results of simultaneous therapy with beta-blockers, anticoagulants, and centrally acting antihypertensives are unpredictable.
Mezapam enhances the effect of phenytoin (possibly slowing down metabolic processes) and reduces the effectiveness of levodopa. Oral contraceptives slow down the metabolism of Mezapam, which can lead to increased duration and increased effectiveness of the medication. Cimetidine extends the period of action and enhances the severity of the pharmacological effect of medazepam.
special instructions
Patients taking long-term beta-blockers, centrally acting antihypertensive drugs, hypoglycemic drugs, oral contraceptives, cardiac glycosides and anticoagulants should prescribe Mezapam with caution (it is impossible to accurately predict the nature of the interaction of these drugs with medazepam).
Therapy should be interrupted in cases of increased aggressiveness, agitation, feelings of fear, thoughts of suicide, hallucinations, and muscle cramps.
When taking Mezapam daily for several weeks, there may be a risk of developing mental and physical dependence (this disorder can be observed both when taking high doses of the drug and when using it in normal therapeutic doses), and therefore continuation of therapy is possible only for health reasons and only after carefully balancing the benefits of the drug with the risk of dependence on it. The risk of developing drug dependence increases in patients who have previously abused ethanol or drugs, as well as when using large doses or increasing the duration of therapy.
Long-term use of Mezapam by pregnant women may cause the development of withdrawal syndrome in the newborn. Taking high doses of the drug immediately before or during childbirth can cause a decrease in blood pressure, respiratory depression, difficulty sucking (“floppy baby syndrome”) and hypothermia in the newborn.
In cases of missing the next dose of Mezapam, it should be taken as soon as it was noticed, but do not double the single dose.
Drinking alcoholic beverages during therapy is unacceptable.
During treatment and prevention of withdrawal syndrome, Mezapam should be discontinued gradually.
During the aftereffect period, severe states of excitation may occur.
It must be taken into account that tension or anxiety associated with everyday stress are usually not indications for prescribing anxiolytics.
Drivers of vehicles and patients whose profession involves increased concentration of attention should take Mezapam with caution (in the first days of therapy, it is recommended to completely refrain from driving vehicles and performing work that requires rapid mental and physical reactions).
Analogs
Pharmaceutical companies produce several drugs that are based on the same active substance as Mezapam. Among them: Rudotel and Nobritem .
Other tranquilizers that do not contain medazepam have similar pharmacological properties:
- Alprazolam;
- Diazepam;
- Zolomax;
- Ipronal;
- Xanax;
- Sibazon.
It is prohibited to independently replace medications or make adjustments to the treatment regimen due to the high risk of harm to health.
Phenazepam
Price from 85 to 120 rubles
Phenazepam is one of the active tranquilizers that affects the functioning of the central nervous system. The medicine has anticonvulsant and hypnotic effects, helps overcome fear, nervous tension and disorder. Recommended for patients with neurotic and psychological disorders. The main component is bromodihydrochlorophenylbenzodiazepine and is sold in tablet form. If you choose which is better, Mezapam or Phenazepam, then there is no clear answer to this question. In this case, the doctor decides, based on the patient’s condition and the course of the disease.
Pros:
- Wide range of uses
- Weak hypnotic effect
- Low cost.
Minuses:
- Long-term use is highly undesirable due to addiction
- There are many side symptoms.
Tranquilizers - what are they?
Tranquilizers are modern sedatives that selectively act on the emotional sphere of the human body. The name "tranquilizer", based on the Latin root tranquillum (peace, tranquility), speaks for itself. The psychotropic effects of drugs in this group are associated with their effect on the limbic system of the brain. They have a pronounced ability to reduce the spontaneous activity of hippocampal neurons. At the same time, tranquilizers have a depressing effect on the hypothalamus and the activating reticular formation of the brain stem. This process helps to reduce the state of internal tension, anxiety, fears, and stabilize the emotional sphere. Since these medications are mainly prescribed to patients suffering from neuroses, they are also called anti-neurotic drugs. Of the most commonly used in medical practice, benzodiazepine derivatives are particularly widespread, as they have a wide range of action and are relatively safe for the patient’s health. Among the drugs in this group, Mezapam is a popular drug; it will be discussed further.
Patient reviews
Yana, 30 years old:
Mom had a very difficult time with menopause. At that moment I was working as a nurse in a clinic. She offered help to a loved one and made an appointment with a neurologist. After the examination, medications were prescribed, among which was Mezapam. The mother’s mental state stabilized after taking a tranquilizer for a week: the quality of sleep improved, excitability and irritability disappeared. The medicine completely coped with the task.
Vladimir Vitalievich, 49 years old:
After the accident at the plant, I began to suffer from panic attacks. A feeling of anxiety and isolation appeared for no reason. As a result of nervous experiences, other health disorders began to appear in a chain reaction: insomnia, decreased appetite, failure of the autonomic system. After much persuasion, my wife signed me up to see a psychotherapist. One of the prescribed drugs was the tranquilizer Mezapam.
I took it for 3 weeks, but improvements became noticeable after 5-6 days. The psycho-emotional state returned to normal, good healthy sleep appeared, and fears disappeared.
Indications for treatment
Indications for the use of Mezapam include the following psycho-emotional disorders:
- neuroses of various etiologies and forms;
- psychopathy, accompanied by nervous excitement, emotional lability, constant tension;
- cardiopsychoneurosis;
- withdrawal syndrome in chronic alcoholism and its treatment;
- disturbances in the emotional state of women associated with the onset of menopause.
Mazepam is prescribed to children for “school” neuroses, hyperactivity, and increased excitability. The drug can be used to prevent migraine attacks in patients who are prone to this pathology. It can be used both for the treatment of situational neuroses (associated with moving to another place of residence, changing jobs, etc.) and for the treatment of chronic disorders of the psycho-emotional state.
In what cases is the drug "mezapam" taken?
As the doctors' reviews of the Mezapam tablets emphasize, they can be classified as so-called daytime tranquilizers, that is, drugs that are practically devoid of muscle relaxant (muscle relaxant) and sedative effects. This makes it possible to take them during working hours without fear of excessive lethargy and drowsiness.
Taking the described drug helps to stabilize the patient’s emotional state, reduce fussiness, maintain the normal state of his autonomic system and restore the ability to adequately assess the situation.
Mezapam tablets are prescribed in the following cases:
- mental and behavioral disorders caused by alcohol withdrawal;
- specific personality disorders;
- nervousness;
- somatization disorders;
- as well as emotional disorders caused by menopause.
They have proven themselves well in the treatment of functional disorders of the cardiovascular system and gastrointestinal tract, as well as as a means of preventing migraine attacks.
Warning to Buyers
In the article, you were offered a description of the drug “Mezapam” (reviews, instructions, price), from which, we hope, you can draw clear conclusions that this drug is effective and relatively inexpensive. At the same time, you should under no circumstances prescribe it to yourself without consulting a specialist.
Incorrect dosage of the drug can lead to tachycardia, catalepsy, a sharp decrease in blood pressure and respiratory depression. This requires urgent medical attention to stabilize the condition and restore basic vital functions.
Remember that these tablets are not a regular sedative. Therefore, by prescribing them yourself, without consulting a doctor, you can cause irreparable harm to your health. Be prudent, don't take risks!
Sources
- https://lekarstva.guru/m/instruktsiya-po-primeneniyu-preparata-mezapam-pokazaniya-analogi.html
- https://medprep.info/drug/medicament/1271
- https://www.rlsnet.ru/tn_index_id_4758.htm
- https://www.webapteka.ru/drugbase/name3835.html
- https://medi.ru/instrukciya/mezapam_11562/
- https://lekhar.ru/lekarstva/preparaty-dlja-nervnoj-sistemy/mezapam-instrukcija-po-primeneniju/
- https://drugs.thead.ru/Mezapam
- https://longnlife.ru/mezapam.html
- https://PsihBolezni.ru/lechenie/mezapam-instruktsiya-po-primeneniyu-otzyvy-pokazaniya-k-primeneniyu-instruktsiya-tsena-analogi-sostav/
- https://Elixir.farm/lekarstva/mezapam/
- https://depressio.ru/lekarstva/anksiolitiki/214-mezapam.html
- https://apteka.ru/preparation/mezapam/
- https://fb.ru/article/217815/mezapam-otzyivyi-vrachey-instruktsiya-tsena
