Release form and composition
Maxicold Lor is available in the form of a spray for topical use: a colorless liquid with a menthol scent (40 ml in aluminum bottles with a dosing pump, 1 bottle in a cardboard box complete with a spray for oral use).
100 ml of spray contains:
- active ingredient: hexethidine – 0.2 g;
- auxiliary components: sodium saccharinate dihydrate, lauromacrogol (macrogol lauryl ether), sodium hydroxide (sodium hydroxide), glycerin (glycerol), rectified ethyl alcohol (ethanol), eucalyptol (cineol), peppermint leaf oil, levomenthol (L-menthol), citric acid monohydrate, purified water.
Possible negative reactions
The drug is usually well tolerated by patients. In some cases, Maxicold Lor spray can provoke unwanted reactions from the body. These include:
- The appearance of allergies.
- Nausea with possible vomiting.
- Taste disturbance.
If any discomfort occurs, you should stop using the drug and consult a doctor. Perhaps he will prescribe a similar drug.
The medication does not affect attention and speed of psychomotor reactions. When using this medicine, you are allowed to drive a car and engage in hazardous activities.
Pharmacological properties
Pharmacodynamics
Maxicold Lor is a spray for topical use. Along with analgesic, enveloping, deodorizing properties, the drug has an antiseptic effect, exhibiting antimicrobial and antifungal activity.
The mechanism of the antimicrobial action of the spray is due to its ability to suppress the oxidative reactions of bacterial metabolism. The concentration of the drug allows it to be active against a wide range of strains of bacteria and fungal infections, including gram-positive bacteria, Pseudomonas aeruginosa, fungi of the genus Candida and Proteus spp., without causing the development of resistance.
Spraying the drug into the oral cavity causes slight anesthesia of the mucous membrane.
Pharmacokinetics
Absorption of Maxicold Lor into the systemic circulation is practically absent.
Traces of hexetidine on the gum mucosa are detected within 65 hours after a single use of the drug. The concentration of the active substance in dental plaques remains active for 10–14 hours.
Therapeutic effect and effect on the body
Maxicold spray is an antiseptic used topically. The medicine is applied to the mucous membrane and has a number of effects, including:
- Antimicrobial
- Deodorant
- Anesthetic
- Antifungal
- Enveloping.
The antimicrobial effect of Maxicold is due to the prevention of oxidative reactions caused by bacterial metabolism.
After a single irrigation of the oral cavity, the local effect exerted by the active substance, hexethidine, can last about 11 hours. There is practically no absorption of the drug from the surface of the mucous membrane. Due to this property, the medicine does not have a systemic effect on the body.
Indications for use
- infectious and inflammatory pathologies of the oral cavity and pharynx, including tonsillitis, Plaut-Vincent sore throat, pharyngitis, glossitis, stomatitis, aphthous ulcers, gingivitis, periodontitis, periodontopathies, alveolitis, periodontal disease, bleeding gums;
- acute respiratory diseases - as part of complex therapy as an adjuvant;
- thrush, fungal infections of the mouth, pharynx and larynx;
- infections during injuries and surgical interventions in the oral cavity, pharynx and larynx - for prevention of development and treatment (including prevention of infection of the alveoli after tooth extraction);
- collapsing tumors of the oral cavity and larynx - to prevent the development of superinfections against their background;
- unpleasant odor in the mouth - as a hygienic (deodorizing) means to eliminate it.
Analogs
When choosing an analogue of Maxicold, you need to take into account that the medication must contain the same active substance. Today the following drugs containing hexethidine are presented on the market:
Aerosol Hexoral
A medicine produced by the American pharmaceutical company Johnson & Johnson.
Average price: 280 rubles.
Has an antimicrobial effect. Indicated for the treatment of colds and treatment of the oral cavity after surgery.
Pros:
- Suitable for treating children over 3 years of age
- The aerosol is safe for frequent use
- There is no evidence of negative effects during pregnancy.
Minuses:
- Contraindicated for use in the presence of allergic reactions to the components
- Long-term use may cause disturbances in taste perception.
You can see detailed instructions for using Hexoral here.
Spray Stopangin
The medicine is produced in Israel.
Average price: 320 rubles.
Pros:
- No cases of drug overdose have been recorded
- Suitable for the treatment of a large number of oral diseases caused by infectious pathogens. Used for oral hygiene and treatment of fungal diseases. Has an analgesic effect.
Minuses:
- The medicine must not be inhaled. In this regard, the medication is only suitable for treating people who are able to hold their breath and adequately perceive treatment
- Not prescribed for children under 8 years of age
- Not suitable for treating women in the 1st trimester of pregnancy.
Instructions for use of Maxicold Lor: method and dosage
Maxicold Lor spray is used topically by spraying onto the affected areas of the mouth and pharynx.
The drug should be used between meals or after meals.
Recommended frequency of procedures: 2–3 times a day. If it is necessary to achieve a more pronounced effect, the spray frequency can be increased.
The duration of the course of therapy is 5–7 days.
Before first use, you must remove the cap from the bottle and, after installing the sprayer, make several test sprays. The drug can be used after visually verifying that the spray is evenly sprayed. Holding the balloon in a vertical position, the sprayer should be inserted into the oral cavity and, while breathing held, press all the way 3-4 times.
After the procedure, the nebulizer should be removed, washed and dried. Store the container with the cap tightly closed.
Pharmacodynamics
Maxicold is a throat spray that has a pronounced antiseptic, antimicrobial, antifungal, and analgesic effect. At the same time, it has a deodorizing and enveloping effect.
The effect of the drug is due to the inhibition of oxidative processes, the development of which is associated with metabolic processes in microorganisms. Thanks to a wide spectrum of activity, an antifungal and antibacterial effect is achieved. Thus, the medicine is effective against gram-positive microflora and candida fungus.
The drug also has a therapeutic effect against infectious diseases caused by the activity of Pseudomonas aeruginosa or Proteus. Resistance to the drug in microorganisms was not observed. The medication is capable of providing a mild local analgesic effect.
With a single use, the effect of the drug continues for the next 10-12 hours.
special instructions
The spray should not be inhaled; contact with the mucous membranes of the eyes should be avoided.
It should be taken into account that the ethanol content in the daily dose of Maxicold Lor is up to 48 mg.
Since the contents of the cylinder are under pressure, it should not be stored near a fire, or attempted to be opened or punctured, even if it is empty.
The content of hexethidine in the recommended dose is not toxic.
Impact on the ability to drive vehicles and complex mechanisms
According to the instructions, Maxicold Lor does not affect the patient’s ability to drive vehicles or operate complex machinery.
Overdose
Data on drug overdose are limited. If the spray accidentally enters the stomach, vomiting develops, preventing further spread of the medication. In case of accidental ingestion of a large amount of spray, you should artificially induce vomiting, rinse the stomach with plenty of water, and take an intestinal sorbent. In children, the development of symptoms similar to intoxication and provoked by the action of ethanol cannot be ruled out.
Side effects from use
There are practically no side effects from the medicinal spray, but the following are possible:
- allergic reactions of the skin and body;
- an unpleasant burning sensation of the mucous membrane in the mouth;
- if the medicine is accidentally swallowed, nausea occurs;
- changes in taste sensations with prolonged use.
Contraindications for use
Intolerance of the body to any component of the spray.
Children under three years of age.
Chronic pharyngitis, accompanied by atrophy of the laryngeal mucosa.
Maxicold tablets and water-soluble powders
The instructions for use recommend starting taking Maxicold ENT medications at the first symptoms of a cold, epidemic flu, or viral infection.
1. One package of Maxicold contains 10 pieces of oval, film-coated tablets, pale orange in color. Active substances:
- paracetamol reduces temperature, relieves headaches, eliminates fever;
- phenylephrine hydrochloride relieves swelling of the nasal mucosa, restores free breathing;
- ascorbic acid supports the body's immune properties.
2. Each sachet of Maxicold drug powder contains: paracetamol 750 mg, phenylephrine 60 mg and ascorbic acid 10 mg. In a cardboard package there are 5, 10 or 50 pieces of packets with pink crystalline powder with a lemon flavor.
Reviews
The drug "Maxicold Lor" receives mostly positive reviews. Many patients note its high effectiveness along with its low cost. The drug can be used to treat children starting from three years of age. It is well tolerated by young patients and does not cause adverse reactions.
Some consumers note that the drug is no different from its analogues. They use it because it is inexpensive. The medication is equipped with a convenient sprayer and is easy to use. Some patients say that one can lasts for a year and a half with infrequent use.
The medicine has a pleasant aroma and taste. It's not bitter. This is especially true for children who do not like to take medications because of their unpleasant taste. When using the spray three times a day, relief occurs on the third day. But some people note that the effect after using the spray only lasts for six hours.
There are also negative reviews about the drug, but there are very few of them. Some patients say that the spray is inconvenient to use, since the sprayer does not work well. It also has a strong taste, which not everyone likes. Some people experience watery eyes and increased salivation. But perhaps this is due to individual intolerance to the active substance. After some time, bitterness begins to appear in the mouth, and sometimes nausea occurs. In addition, the effect of the drug is observed for only a few hours, then all the unpleasant symptoms of the throat disease return.
Thus, the drug "Maxicold Lor" has an acceptable cost and is effective for the treatment of diseases of the oral cavity. But it is best to use it in complex therapy of pathologies. Doctors often prescribe it to their patients. Relief occurs within ten minutes after using the spray and lasts about six hours, so it is recommended to use it three times a day. Some doctors say that the spray is not used as an independent remedy for severe sore throat. For example, if you have a sore throat, it is better to take additional tablets.
