Argosulfan ointment is a medicine with antibacterial activity for external use. The drug has disinfecting and restorative properties. Used to heal wounds of any nature and prevent their infection. The active substance of the drug is effective against most gram-positive and gram-negative bacteria. Before starting to use the ointment, you should read the instructions and patient reviews of the product.
general description
Argosulfan is a white cream with a pink or light gray tint. The active component is silver sulfathiazole, 20 mg per 1 g of cream. Additionally, the drug contains the following substances:
- sodium salt of lauryl sulfuric acid;
- preservative E218 (methyl parahydroxybenzoate);
- sodium dihydrogen orthophosphate;
- propylparaben;
- cetyl alcohol;
- glycerol;
- purified water;
- white and liquid Vaseline.
Additional substances of the drug are selected in such a way as to well moisturize problem areas and maintain the pH balance necessary for rapid healing and restoration.
The product is packaged in aluminum tubes, the volume of which can be 15 or 40 g. The original cardboard pack contains one tube and an insert sheet (instructions for use), which presents all the detailed characteristics of the medication.
Argosulfan ointment is produced in Poland: Elfa JSC Farmzavod (Pharmaceutical Works Jelfa, SA) and Russia: Valeant LLC.
Pharmacological action of the drug Argosulfan
Antimicrobial agent with silver Argosulfan produced pharmaceutically (Poland) or (Russia) is available in the form of a 2% ointment in an aluminum tube of 15 g and 40 g.
Ointment for bedsores with silver Argosulfan prevents infection of open wounds, has a wound healing effect, and also reduces pain. With timely use of the drug, tissue transplantation can be prevented. The active substance, silver sulfathiazole, has an excellent antibacterial effect. Thanks to it, the area of infection of the skin is reduced and the proliferation of pathogenic microorganisms is prevented. The optimal acidity level of the Argosulfan ointment base ensures moisturization of the skin, relief of the body's condition and good tolerability of treatment in general.
Pharmacological characteristics
The therapeutic effect is based on the active component - silver sulfathiazole, which has pronounced antimicrobial activity. The substance is especially active against gram-negative bacteria. Blocks the synthesis of folic acid in the microbial cell. Silver ion inhibits the growth and doubling of DNA (bactericidal effect), enhances the effect of sulfathiazole, and weakens the allergenic properties inherent in sulfonamides. Accelerates the healing of wounds, bedsores, burns, trophic ulcers. It is practically not absorbed from the application site. Low solubility and resorption ensure constant concentration in the wound and a virtual absence of systemic manifestations of toxicity.
Thus, Argosulfan:
- destroys pathogenic microorganisms in the wound;
- prevents infection from penetrating deep into the affected tissues;
- removes toxins from the wound that arise due to inflammatory processes;
- accelerates the restoration of damaged tissues (rapid healing and scarring occurs);
- has a local anesthetic effect;
- reduces regeneration time at the cellular level.
Silver sulfathiazole has poor solubility, so after application to the wound, its concentration remains unchanged for a long time. Only a small amount enters the systemic circulation and is then acetylated by the hepatic system. Metabolites are excreted from the body by the kidneys along with urine.
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Reviews
Olga, 38 years old, Stavropol
About 3 years ago, my grandmother used this product. She used Argosulfan ointment to treat a trophic ulcer on her toe, which had formed due to diabetes mellitus. The case was so advanced that doctors seriously thought about amputating the phalanx. But in 2.5 weeks the situation changed for the better, and during this period only this drug was used. The wound began to heal already on the 5th day. I think this is one of the best ointments for all kinds of skin damage. Don't risk your own health and don't buy cheap substitutes. You won't get the same effect!
Evgeniy, 25 years old, Murmansk
I used Argosulfan after removing a large mole. Ich appeared on the skin, and the wound itself did not want to heal. I was very afraid of oncology, so I made an appointment with a dermatologist, who prescribed this ointment. In just 7 days there was no trace left of the problem! The wound “dried up” literally before our eyes. Try it, you won't regret it!
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Argosulfan ointment (review) from 340 rub.
Overall
4.6
- Efficiency
- Price
- Safety
- Availability
Pros
- Efficiency
- Economical consumption
- Without smell
Cons
- Price
Indications and contraindications for use
Argosulfan ointment is used in the following cases:
- solar, thermal, chemical, radiation burns of any degree;
- specific skin damage caused by low temperatures - frostbite;
- minor injuries received at home (abrasions, cuts);
- necrosis (necrosis) of soft tissues as a result of constant pressure - bedsores;
- trophic ulcers of the leg of various origins (including chronic venous insufficiency, obliterating endarteritis, angiopathy in diabetes mellitus, erysipelas).
In addition, the ointment is prescribed for some dermatological problems. For example, contact or infected dermatitis, microbial eczema, impetigo, endarteritis. Argosulfan is also used in skin transplantation, treating it before and after surgery.
The drug is not prescribed for the following conditions:
- high sensitivity to the components of the drug;
- state of shock with extensive burns;
- premature babies;
- children up to 2 months;
- congenital deficiency of glucose-6-phosphate dehydrogenase.
Kidney and liver failure require careful use of the ointment.
Argosulfan during pregnancy and breastfeeding is prescribed only after assessing the ratio of expected benefits to possible risks in cases where the burn area does not exceed 20% of the body surface.
Application area
Argosulfan is a broad-spectrum drug. It is active against streptococcal, staphylococcal, fungal and parasitic infections. Application area:
- treatment of frostbite and burns of any origin;
- non-healing ulcers formed as a result of tissue trophic disturbances (varicose, diabetic, erysipelas and others);
- festering wounds;
- skin diseases complicated by infection, bacterial eczema, streptococcal and staphylococcal pustular skin diseases.
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Argosulfan ointment helps against bedsores and treats sunburn
. Another purpose of the cream is preparation for skin grafting.
At the same time, the drug heals the damaged surface so well that transplantation of skin flaps may not be necessary.
Thanks to its antimicrobial and restorative effect, the cream helps against acne.
Argosulfan is widely used in everyday life to treat cuts and abrasions. It is used to treat boils and calluses.
Method of application (dosage, method)
Argosulfan cream is for external use only. Treatment is carried out using both the open method and the use of occlusive dressings. Before using the product, the wound is pre-treated with any antiseptic. If purulent fluid is released, it is also removed with an antiseptic, for example, chlorhexidine solution.
Then a thin layer (no more than 2-3 mm) is applied to the ointment. The procedure is carried out 2-3 times a day. Treatment is carried out until the clinical manifestations disappear completely. The maximum daily dosage is 25 g of ointment. The course of therapy should not exceed 2 months.
On a note
- Argosulfan is an ointment with silver for wound healing, has an antibacterial effect.
- Used to treat acne at home.
- Allowed for use by children only after 3 months.
- Before applying the ointment, the surface should be treated with an antiseptic.
- The cost of the drug ranges from 280 rubles and above.
The material was prepared specifically for the website mazikrem.ru, edited by doctor Kantser M.A. Specialty: infectious diseases, general hygiene, virology.
Side effects, overdose
Allergic manifestations on the skin are the only possible negative consequence of using Argosulfan ointment. Burning and redness at the application site is a rare occurrence. If you use the drug for more than a month, there is a possibility of changes in the blood picture. This is due to prolonged exposure to the active component.
No cases of overdose have been officially registered. If, while using Argosulfan ointment, any nonspecific symptoms occur, you should consult a doctor.
Interaction, special instructions
Argosulfan is not recommended to be combined with other drugs for external use. Folic acid and its structural analogues may weaken the antimicrobial effect of sulfathiazole.
In chronic renal failure, the concentration of sulfathiazole in the blood plasma should be monitored.
The drug does not affect the central nervous system in any way. Therefore, during therapy with Argosulfan, it is allowed to drive a car and engage in activities that require concentration and precision of action.
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Conditions of release and storage
The drug is dispensed from pharmacies without a doctor's prescription. The shelf life is 2 years from the production date, which is indicated on the branded pack and tube. You cannot use a product that has expired. The ointment should be stored in a dark place away from direct sunlight and limited access to children and pets. Storage temperature should not exceed 25°C. Freezing the medication is prohibited.
The price of the drug depends on the region where it is sold and the pricing policy of the pharmacy. In Moscow and the Moscow region, the cost of Argosulfan cream for external use is 2%, 40 g tube - from 550 rubles.
Available analogues
The drug Argosulfan has no structural analogues of the active substance. If necessary, you can replace the ointment with the following medications:
- Streptocide is an antimicrobial sulfonamide drug from a group of chemotherapeutic drugs with a selective bacteriostatic effect. Prescribed to combat skin pathologies caused by the activity of pathogenic bacterial flora.
- Dermazin is an antibacterial drug. Used for the treatment and prevention of infected trophic ulcers and wounds, burn infections. Thanks to the silver sulfadiazine included in its composition, Dermazin has a wide spectrum of antibacterial action, which applies to almost all types of microorganisms that can infect burn wounds.
- Sulfargin is an external drug with antibacterial, bactericidal and antifungal effects. The medication is active against gram-negative/gram-positive bacteria (Proteus spp., Escherichia coli, Klebsiella spp., Staphylococcus spp.), as well as dermatophytes and fungi Candida spp.
- Advantan is an antibacterial, antiallergic, non-halogenated steroid that is successfully used in the treatment of various dermatoses. Methylprednisolone aceponate is the active substance.
- Depanthenol is a regenerating, dermatoprotective drug. Indications for use: dry skin, abrasions, cracks, burns, minor injuries, abscess, boils, bedsores, diaper rash.
All of the listed medications are analogues of Argosultan, which have the same list of indications. A substitute should be selected by the attending dermatologist, who assesses the severity of the disease, the individual characteristics of the human body and other important factors.
Selection and purchase of ointment
When choosing an ointment, be guided by the size of the tube. So, for wounds of mild severity, you can purchase a tube with a volume of 15 grams, but if you need to use it for wounds with suppuration, bought for bedridden patients with bedsores, then it is better to purchase a tube of 40 grams.
Analogs
If you have an allergy or other undesirable reactions to the drug, Argosulfan ointment has analogues.
Drugs such as Argedin and Sulfargin will help in the treatment of infected wounds, burns, and abrasions.
Wundehil will help with bedsores.
Solcoseryl and Videstim increase the intensity of regenerative processes.
For purulent wounds and trophic ulcers, Levomekol is used.
