Shampoo with Ketoconazole, antifungal Nizoral, Climbazole and Kenazol - which is better for fungus and dandruff on the head

Human skin is home to many pathogenic microorganisms, in particular the yeast-like fungus Malassezia furfur. Weakening of the immune system, chronic diseases and disturbances of internal processes in the body can provoke their increased reproduction. Such changes cause itching, active flaking of the scalp and the appearance of dandruff in the hair, and the disease itself is called seborrheic dermatitis. Nizoral shampoo is a medicinal product designed to suppress the activity of yeast. It will quickly and without harm eliminate the cause of dandruff, alleviate the symptoms of the disease and speed up recovery. The high cost of the drug sometimes stops patients: how justified these expenses are, we will try to figure it out further.

pharmachologic effect

Manufacturer: JANSSEN PHARMACEUTICS N.V. (Belgium)
Release form: shampoo, tablets, cream for external use

Active ingredient: ketoconazole

Analogues: Keto plus, Sebazol, Sulsena

Nizoral belongs to the group of antifungal drugs that are active against dermatophytes, yeasts, dimorphic fungi and zoumicetes. The active substance of the drug inhibits biochemical synthesis in the cellular structures of fungi, which leads to their destruction.

Description of the disease

The disease develops in several stages. During the first, yellow-pink spots appear on the body, which can cover a significant part of the body. They cannot be on the palms, heels and mucous membranes. These spots change color, which is why lichen is also called multicolored. It can take on a variety of shades. Clear foci appear in place of former spots. Peeling of the skin begins, without itching. There is discomfort.

https://www.youtube.com/watch?v=EbiTmTFOf2I

Pregnant women often suffer from the disease, because in people who are predisposed to this disease, pregnancy is its stimulator. Shampoos and shower gels for lichen are safe for expectant mothers, provided there is no allergy to one of the components of the drug.

If you have this condition, you should consult a doctor. He will make a diagnosis and prescribe the correct treatment. You cannot self-medicate. Pityriasis versicolor is very easy to confuse with other skin diseases.

Indications for use of Nizoral

Nizoral is prescribed for the following diseases:

• seborrheic dermatitis;
• dandruff caused by various reasons;
• athlete's foot and hands;
• dermatomycosis of the skin;
• pityriasis versicolor;
• pityriasis versicolor;
• candidiasis of various localizations;

Nizoral, depending on the affected area, is used as an external remedy (cream, shampoo) for skin diseases or for internal use (tablets) when candidiasis is localized in the pharynx, vagina, or oral cavity.

How to recognize quality shampoo

Trichologists recommend paying attention to the following characteristics of shampoo when purchasing:

• Thick liquid consistency.
• Comprehensive hair care.
• The composition contains herbal extracts and essential oils.
• No harsh sulfates, mineral oils or artificial flavors (DEA, MEA, TEA)
• Low foaming.
• No pungent odor.

It is better to purchase medicinal shampoo for dandruff at a pharmacy.
To quickly eliminate dandruff, along with washing your hair, it is recommended to adhere to a healthy lifestyle and rationalize your diet.

In addition, the following helps get rid of dandruff:

• regular cleaning of hats
• cleaning combs and hair clips
• head massage.

Nizoral - instructions for use

According to the instructions for use of Nizoral, the drug is prescribed as:

• Creams - for the treatment of skin candidiasis, athlete's foot, pityriasis versicolor, the product is applied to the affected area of ​​the skin once a day, including a portion of healthy skin. According to indications, the frequency of application of the medicine can be increased to 2 times a day for a duration of 3 weeks to 1.5 months.
• Shampoo - for the treatment of dandruff and seborrheic dermatitis, the product is applied to the affected areas for 4-5 minutes 2 times a week, followed by rinsing with warm water. The course of therapy continues for 2–4 weeks. Treatment for pityriasis versicolor is carried out once a day and lasts for 5 days.
• Tablets - for the treatment of infections of the skin, scalp, mucous membranes or infectious processes of a systemic nature, provoked by yeast fungi, dermatophytes. The medication is prescribed 1 tablet per day. The duration of therapy can range from 1 week to 6 months, depending on the type and location of the pathology.

The treatment process must be continuous and with a laboratory result indicating the absence of the pathogen.

Comparison of addiction between Nizoral and Sebozole

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Nizoral is quite similar to the similar values ​​in Sebozole. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Nizoral has a fairly low incidence of “syndrome”, just like Sebozole.

Analogues of Nizoral shampoo

The pharmaceutical market is largely represented by foreign and Russian analogues of Nizoral shampoo for the treatment of diseases caused by dermatophytes, fungi, and yeasts. They have equivalent indications and treatment results. They are sold in the pharmacy chain in the form of:

• synonyms;
• combination drugs;
• generics.

The variety of substitutes for Nizoral shampoo allows you to select the appropriate analogue for your skin type in each individual case, taking into account the spread of the pathological process and the degree of its activity.

Table of analogues of Nizoral shampoo with price and country of origin

The price of Nizoral shampoo analogues varies widely. You can buy medicinal anti-dandruff shampoo at a cheap price with a good therapeutic effect from a Russian manufacturer.

Recommend anti-dandruff shampoo. Anti-dandruff shampoo, which company is better to choose?

This is what the TOP of the best manufacturers of shampoos for seborrhea looks like:

• Alerana is a brand specializing in the creation and sale of cosmetic products for hair care. First of all, it is aimed at slowing down the process of hair loss on the head, accelerating its growth and increasing its volume. The brand's shampoos are produced in convenient plastic packaging, foam well, spread easily over the surface and are easily washed off the skin.
• Sulsena is a trademark. Her anti-dandruff shampoos are medicinal and are recommended for use by trichologists. With their help, the problem is not masked, but is eliminated by normalizing the production of subcutaneous sebum and thoroughly cleansing dead scales. There are practically no contraindications for the use of these funds.
• Cynovit is a trademark. It produces a series of care cosmetics for hair restoration, which also includes anti-seborrhea shampoos. They are distinguished by their optimal consistency, pleasant smell, low likelihood of side effects, ease of application and rinsing off residues. These products help in a short time, in about 4-7 applications, and these results last a long time.
• Dionysus is a Russian company producing care products and household chemicals. It uses highly active components, which guarantees the safety of the products for health. Usually they do not contain dyes, parabens, fragrances, and the likelihood of allergies is reduced to almost zero. Its compositions are suitable for frequent washing of hair of any type - oily, dry, normal, problematic. In this rating, the manufacturer is represented by one of its best medicated anti-dandruff shampoos, Sebozol.
• Vichy is a French manufacturer of premium cosmetics, including hair products. It focuses on versatility, safety, and quick results. The products from this company are interesting because of their large volume, good consistency, adequate smell, and the absence of an allergic reaction to the compositions. The compositions are packaged in plastic bottles and sold both in stores and pharmacies.
• Clear is a brand that produces high-quality hair care products. It is actively used not only at home, but also in beauty salons. It has proven itself to be safe, reliable, and effective due to the content of numerous highly active substances and the absence of various dangerous additives of unnatural origin in the composition.
• Schwarzkopf - the company produces a series of Schauma shampoos, which are successfully used to treat seborrhea in both the initial and advanced stages. They are effective in combating both dry and oily dandruff, restore the synthesis of subcutaneous sebum, and carefully cleanse the skin of exfoliated white scales. On average, with their help the problem is solved in 3-4 weeks.
• Head&Shoulders - what sets this company apart from its competitors is its focus on the production of shampoos specifically to combat dandruff. The company was founded in 1961, its main office is located in the USA, it belongs to the American concern Procter & Gamble. The advantages of its proposals are adequate cost, safe composition, absence of unpleasant odor, good texture, excellent foaming.
• Estel is a brand under which professional products for hair and skin care for men and women are supplied to the market. Its assortment includes various sprays, masks, gels, balms, and shampoos. Among the latter, a therapeutic series of compositions to combat seborrhea deserves special attention. Usually it helps in 5-7 applications, is used in courses and has a complex effect: it gives shine to curls, strengthens their roots, and eliminates static electricity.
• Mustela is a children's brand that has many baby care products, including shampoos. They are intended for exfoliation of seborrheic crusts with mild, medium and severe dandruff. After their use, no unpleasant sensations arise and children react normally to such drugs, without being capricious.
• Freederm is an Italian brand under which products are developed and manufactured to combat seborrhea at all stages. The brand's products are recognized by dermatologists and trichologists as effective based on numerous tests. What makes these anti-dandruff shampoos good is the low likelihood of side effects and the rapid restoration of hair.
• Fitoval is a manufacturer from Slovenia that offers shampoos in several volumes to eliminate seborrhea: 100, 200, 400, 1000 ml. By purchasing larger quantities you can usually save some money. The brand's products are suitable for all hair types and can be used on a regular basis to prevent seborrhea, and in courses to treat it.

Nizoral shampoo or Keto plus - which is better?

Manufacturer: GLENMARK PHARMACEUTICAL LTD (India)
Release form: shampoo

Active ingredient: ketoconazole, zinc pyrithione

Both shampoos have the same indications and are used to eliminate dandruff, seborrheic dermatitis or pityriasis versicolor. According to patient reviews, this analogue of Nizoral will be the best, since Keto Plus shampoo has an additional active ingredient in the form of zinc.

The shampoo quickly eliminates itching and flaking of the skin by slowing down and stopping the growth of fungus, and also normalizes the production of sebaceous secretions.

Comparison of the safety of Nizoral and Sebozole

The safety of a drug includes many factors.

At the same time, in Nizoral it is quite similar to Sebozol. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Nizoral, as well as Sebozol, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Nizoral does not have any risks when used, just like Sebozole.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Nizoral and Sebozol.

Nizoral or Sulsena - which is better?

Manufacturer: MIRROLA (Russia)
Release form: shampoo

Active ingredient: selenium disulfide

Nizoral and its analog Sulsena have the same indications. But the best treatment for dandruff caused by a fungus is Nizoral, since its active substance ketoconazole acts directly on the pathogen, inhibiting it.

Sulsen's analogue is more suitable as a prophylactic agent that exhibits antifungal properties, although it does not contain components that directly affect the fungus.

Dermazol

Contains 2 main components: ketoconazole and zinc pyrithione. They help a person get rid of lichen that affects the epidermis and hair, and relieve unpleasant symptoms - itching, irritation, dryness, flaking. Ketoconazole stops the growth of sunburn spots; they disappear after a few days. The sebaceous glands begin to work better.

Application regimen: 1 time daily for 1-2 weeks. But real reviews report that 2 weeks is not enough.

It is often necessary to extend therapy for 2-3 weeks. Rarely, a person develops an allergy, hair color changes, dryness, flaking of the scalp occurs. The cost of a 100 ml bottle in pharmacies varies between 200-300 rubles.

Mycozoral

Manufacturer: MEDANA PHARMA JSC (Poland)
Release form: medicinal shampoo

Active ingredient: ketoconazole

Mycozoral in the form of 2% shampoo is an effective antifungal agent that has an inhibitory effect on staphylococci and streptococci. This active ingredient analogue of Nizoral is applied selectively only to problem areas of the scalp for 4–5 minutes, followed by rinsing off the shampoo with warm water.

The presence of the active substance in the detergent ensures rapid relief of pathological symptoms (itching, flaking) and restoration of the affected areas of the scalp.

What else can you use to replace Nizoral shampoo, what detergents are effective against fungus? You can supplement the list of medications with the following drugs:

• Orazol;
• Dermazol;
• Dandruffed;
• Kanazol;
• Friderm;
• Ebercept.

A large selection of medicinal products for external use allows patients to purchase analogues of Nizoral shampoo cheaper, but with a good antifungal effect.

Side effects

Despite the safe dosage of the active substance and synthetic additives in the shampoo, the risk of side effects is not denied . These include:

• allergic rashes at the site of application;
• swelling of the tongue, pharynx, which can make it difficult for the patient to breathe;
• dizziness;
• increased itching.

If such signs are detected, immediately rinse the composition from your head with plenty of water and contact a specialist.

The following side effects are considered quite acceptable:

• the appearance of acne on the scalp;
• increased oiliness and dryness of hair;
• slight changes in the color of gray or previously colored hair.

There is no need to take any measures to eliminate them; the unpleasant symptoms will go away on their own after the end of the treatment course.

You can see the positive results after using the shampoo in the before and after photos.

Analogues of Nizoral tablets

In some cases, it is necessary to supplement the treatment of pathologies caused by fungi with the internal use of Nizoral tablets. If for some reason (contraindications) they cannot be taken, they can be replaced with analogues that provide an equivalent therapeutic effect. The most common analogues of Nizoral tablets in composition are medications based on:

• Fluconazole is Fucis, Diaflu, Diflazon, Mikamax, which are used orally for damage to the mucous membranes (candidiasis of the throat, genitals, candidal balanitis) and extensive damage to the skin.
• Itraconazole is Itracon, Izol, Funit, which are active against yeast fungi, dermatophytes and are used to treat generalized forms of candidiasis and systemic mycoses.
• Terbinafina is Lamikon, Atifan, Lamifen, Terbizil, which have a wide spectrum of antifungal action and are used for the treatment of dermatomycosis, mycoses of the scalp, and candidiasis.

Among these medications, there are analogues of Nizoral tablets that are cheaper, but highly effective. Is it still possible to supplement or replace Nizoral tablets with something? For common pathological processes, combination treatment is used to enhance the effect, combining the use of tablets and external agents.

Comparison of side effects of Nizoral and Sebozole

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Nizoral has more adverse effects than Sebozole. This implies that the incidence is low with Nizoral and low with Sebozole. Frequency of manifestation is an indicator of how many cases of an undesirable effect from treatment are possible and registered. The undesirable effect on the body, the strength of influence and the toxic effect of drugs are different: how quickly the body recovers after taking it and whether it recovers at all. When using Nizoral, the body's ability to recover faster is higher than that of Sebozole.

Analogues of Nizoral cream

In clinical dermatology, analogues of Nizoral ointment are also used, prescribed for fungal skin lesions, which include:

• Mycozoral;
• Dermazol;
• Mycozolon;
• Lamisil;
• Zalain;
• Candide;
• Ecodax.

Patients for the treatment of fungal skin diseases can choose cheaper analogues of Nizoral cream. Their budget cost makes it possible to purchase and combine products for long-term treatment for fungal infections of the skin.

Properly selected analogues of Nizoral and their use in treatment make it possible to quickly cope with the damaging effects of the fungus.

Comparison of the effectiveness of Nizoral and Sebozole

Nizoral is more effective than Sebozole - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Nizoral is more pronounced, then with Sebozole it is impossible to achieve this effect even in large doses.

Also, the speed of therapy is an indicator of the speed of the therapeutic action; Nizoral and Sebozole are also different, as is bioavailability - the amount of the drug reaching the site of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.