Spasmalgon is a combined analgesic with pronounced antispasmodic activity. The drug Spazmalgon contains three active components - metamizole sodium, pitofenone hydrochloride and fenpiverinium bromide.
Release form: round, flat tablets with a bevel and a score on one side, white or almost white. The composition of the medicine (in each tablet) includes:
- Metamizole sodium - 500 mg
- Pitophenone hydrochloride – 5.0 mg
- Phenpiverinium bromide – 0.1 mg
Compound
The drug contains metamizole sodium , pitofenone (antispasmodic myotropic agent) and fenpiverinium bromide (m-anticholinergic).
Spazmalgon tablets contain 500 mg + 5 mg + 100 mcg of active ingredients, respectively. Additional elements are: gelatin, lactose monohydrate, magnesium stearate, wheat starch, sodium bicarbonate, talc.
The solution contains active ingredients in the amount of:
- 500 mg + 20 mcg + 2 mg;
- 1000 mg + 40 mcg + 4 mg;
- 2500 mg + 100 mcg + 10 mg.
And also injection water.
Similar means
If it is not possible to use Spazmalgon to reduce stomach pain, doctors may recommend a drug that has a similar composition and has an identical principle of action. These include:
Spasmalin is a remedy that has a similar principle of action on the body.
- "Plenalgin";
- "Spazmalin";
- "Took";
- "Renalgan";
- "Spasmoblock";
- "Maxigan";
- "Revalgin";
- "Baralgetas"
- "Spazgan".
Indications for use of Spazmalgon
What do pills and injections help with? For pain syndrome of mild and moderate severity, for renal, hepatic colic, algodismenorrhea . Can be used for symptomatic, short-term treatment of neuralgia, joint pain, myalgia, and sciatica.
What else are these tablets used for and for what purpose? They are used as an auxiliary pain reliever after diagnostic and surgical interventions. Spazmalgon helps with headaches, toothaches, and menstruation.
Also, indications for the use of Spasmalgon are infectious-inflammatory and colds, in which the drug effectively reduces elevated body temperature.
Combination with other drugs
A huge number of Spazmalgon analogues are available for sale: Baralgetas, Baralginus, Bral, Bralangin, Maxigan, Realgin, Renalgan, Reonalgon, Spazgan, Spazmadol, Spazmil, Spazmogard, Plenalgin and other drugs.
The decision to replace the drug must be made by a specialist. Analogues according to the ATX code are: Spasmopharm, Maxigan, Baralgetas, Renalgan, Bralangin.
When used together, spasmalgon with other drugs can increase intoxication of the body. Use drugs together only as directed by a doctor. If the patient has problems with the kidneys or liver, then you should consult a doctor about taking smazmolgon to avoid negative consequences.
Spasmalgon is a combined analgesic drug that has a pronounced analgesic and antispasmodic effect. The main active ingredient is analgin. Spasmalgon, in addition to relieving pain symptoms, normalizes elevated body temperature and has an anti-inflammatory effect.
The active components of the drug are quickly absorbed into the mucous membranes of the digestive system and are evenly distributed throughout the soft tissues of the internal organs. The peak effect of the drug after its use occurs within 1-2 hours.
The first effect, manifested in a significant reduction in the intensity of the pain symptom, occurs after 10-15 minutes. The components of the drug are removed from the body through waste by-products, mainly urine.
It is forbidden to take Spazmalgon with non-steroidal anti-inflammatory drugs, as this will lead to the development of severe side symptoms. The simultaneous use of Spazmalgon and alcoholic beverages is excluded.
Contraindications
Allergy to components of the drug, pyrazolone . Stable, unstable angina , suppression of bone marrow hematopoiesis, chronic heart failure (stage of decompensation ), serious disorders of the kidneys, liver, tachyarrhythmia, prostatic hyperplasia with urinary retention, angle-closure glaucoma, granulocytopenia, megacolon, pregnancy, breastfeeding. The drug is contraindicated for use in children under 6 years of age. Spasmalgon is prescribed with caution for diseases of the renal and hepatic systems, low blood pressure (systolic reading below 100 mm Hg), a contraindication is a tendency to bronchospasm.
Analogs
Despite the presence of a combined composition, you can find a sufficient number of analogues of the drug Spazmalgon in pharmacies.
Spazgan
It is a direct analogue of Spasmalgon. It is a combined antispasmodic and analgesic. Available in the form of tablets and solution for injection. It is distinguished by the presence of packaging containing 10 and 100 units of tablet form. The injection solution is packaged exclusively in ampoules of 5 ml.
Cyclopar
It is an indirect analogue of Spasmalgon. It has a combined composition, which includes dicycloverine and paracetamol. Available in tablet form. It can be used to treat dental and menstrual pain. Contraindicated for children under 6 years of age.
Pentalgin
Belongs to the group of antispasmodics, analgesics and antipyretics with a combined composition. The active ingredients are: caffeine, paracetamol, drotaverine, naproxen and pheniramine. Can be used to relieve fever and pain associated with colds. Has anti-inflammatory activity.
Side effects
Dry mouth, burning sensation in the epigastrium . Dizziness, headaches, decreased sweating, difficulty urinating, accommodation paresis. Cyanosis , tachycardia , decreased blood pressure. Oliguria , renal dysfunction, anuria , interstitial nephritis, polyuria , red urine color. Agranulocytosis, leukopenia, thrombocytopenia - with long-term use. Allergic reactions: bronchospasm, urticaria, anaphylactic shock, Stevens-Jones syndrome, Lyell's syndrome, Quincke's edema .
Instructions for use of Spazmalgon (Method and dosage)
Spazmalgon tablets, instructions for use
Adults, children over 15 years old: 1-2 tablets after meals 2-3 times a day. The maximum daily dose should not exceed 6 tablets. The period of admission is no more than 5 days.
Spazmalgon for children: 6-8 l – 1/2 tablet, 9-12 l – ¾ tablet, 13-15 l – 1 t. 2-3 rubles per day.
Instructions for use of Spazmalgon in ampoules
Injections are given up to 5 ml 3 times a day. The maximum dose is 10 ml. The product is usually used for 5 days.
Before use, the ampoule must be warmed in your hands.
Use for stomach pain
You should not self-medicate; the dosage and duration of medication should be determined by a qualified physician, relying on the patient’s test results and his condition.
Usually, to relieve pain due to gastritis or other pathologies of the gastrointestinal tract, an antispasmodic drug is prescribed in 1-2 tablets. The medicine should be taken after meals; it is strictly not recommended to use Spazmalgon on an empty stomach. The next tablet can be taken no less than 6 hours later.
Interaction
Spasmalgon and non-narcotic analgesics, when taken simultaneously, can lead to increased toxic effects of the drugs. Allopurinol , COCs, tricyclic antidepressants disrupt the metabolism of metamizole in the liver, resulting in increased toxicity. Inducers of microsomal liver enzymes reduce the effectiveness of metamizole. Tranquilizers and sedatives increase the severity of the analgesic effect. The simultaneous use of cyclosporine and spasmalgon reduces the concentration of the former in the blood. Spasmalgon enhances the effect of ethanol. Concomitant use with phenothiazine derivatives increases body temperature. Cytostatics and thiamazole increase the risk of developing leukopenia. The effectiveness of the drug is increased by H2-histamine receptor blockers, codeine , propranolol .
special instructions
When taking the drug for more than 7 days, it is necessary to monitor the peripheral blood picture and evaluate the condition of the liver. If thrombocytopenia is present or agranulocytosis is suspected, it is necessary to stop using the drug. Drinking alcohol is prohibited during treatment. Spasmalgon reduces the speed of mental and physical reactions.
Does the drug increase or decrease blood pressure?
The medicine is not used to stabilize blood pressure, however, when using the medicine, spasms of blood vessels are relieved, which may result in a decrease in blood pressure.
Spasmalgon
Spasmalgon (metamizole sodium + pitofenone + fenpiverinium bromide) is a non-narcotic antispasmodic analgesic used to reduce or relieve pain of mild or moderate severity. Drug therapy for pain and optimization of its effectiveness is one of the key areas in the scientific research of therapists, surgeons, oncologists, traumatologists and doctors of other specialties. At the same time, narcotic analgesics remain one of the main groups of drugs used for these purposes. Despite their effectiveness in relieving pain, these drugs provoke lethargy, passivity, drowsiness, and, most dangerous of all, the formation of pathological dependence. A real revolution in the pharmacotherapy of pain was the discovery of the mechanisms of pain development and inflammatory reactions. The role of biologically active substances of the prostaglandin and kinin series - mediators of pain and inflammation - was established. Reducing the production of these mediators, combined with blunting pain sensitivity (due to inactivation of the corresponding receptors), has become the main goal of pain therapy. The use of combinations of analgesics and drugs that exhibit synergism in relation to each other and have complementary mechanisms of action is a key approach to increasing the effectiveness of relieving pain of various etiologies. The analgesic properties of Spasmalgon from the Bulgarian pharmaceutical make this drug one of the most popular among both doctors and their patients, because The drug's over-the-counter status makes it accessible to the widest segments of the population. One of the key active ingredients of this medicine is metamizole sodium.
This substance, which has analgesic, antipyretic and anti-inflammatory effects, was first synthesized in 1921 and has since become widespread in the global pharmaceutical market. All three substances included in Spasmalgon potentiate each other’s therapeutic effects, which is reflected in more effective pain relief, muscle relaxation, and normalization of body temperature. Pitophenone hydrochloride has a direct muscle relaxant effect on the smooth muscle framework of internal organs. Phenpiverinium bromide, being an M-anticholinergic blocker, exhibits an additional muscle relaxant effect on smooth muscles. Clinical studies have shown that smooth muscle spasm is not only a pain syndrome, but also a trigger for many diseases. Spasm causes tissue ischemia, followed by swelling, pain and increased spasm. In such cases, spasmalgon allows you to quickly and effectively improve the patient’s condition. With prolonged (more than seven days) use of the drug, medical monitoring of the peripheral blood picture and monitoring of the functional state of the liver is indicated. If there is a pathological decrease in the level of leukocytes or platelets, drug therapy should be interrupted. Spazmalgon is not compatible with ethanol, so alcohol consumption should be avoided when taking the drug. The combined use of Spazmalgon and other non-narcotic painkillers within the same drug course can lead to mutual potentiation of toxic effects. Barbiturates (phenobarbital) weaken the effect of one of the components of the drug - metamizole. Tranquilizers enhance the analgesic effect of Spazmalgon.
Spasmalgon's analogues
Level 4 ATX code matches:
Spazgan
Renalgan
Baralgetas
the drugs : Baralgetas , Baralgin , Baralginus , Bral , Maxigan , Realgin , Spazgan , Spazmadol , Spasmogard , Trinalgin .
Spasmalgon price, where to buy
The price of Spazmalgon in tablets of 20 pieces per package is 130 rubles.
The cost of 10 ampoules of 2 ml solution is 240 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Spazmalgon effect tablets pp.o. 30 pcs. Balkanpharma-Dupnitsa AD
373 rub. order - Spazmalgon tablets 10 pcs.Balkanpharma/Zdravle HFZ
RUB 149 order
- Spazmalgon tablets 20 pcs.Balkanpharma/Zdravle HFZ
RUB 149 order
- Spazmalgon effect tablets p.p.o 10 pcs. Balkanpharma-Dupnitsa AD
RUB 144 order
Pharmacy Dialogue
- Spazmalgon tablets No. 10Zdravlje
119 RUR order
- Spazmalgon Effect tablets No. 10Balkanpharma Dupnitza AD
RUB 151 order
- Spazmalgon Effect tablets No. 30Balkanpharma Dupnitza AD
RUB 367 order
- Spazmalgon tablets No. 20Zdravlje
185 rub. order
- Spazmalgon tablets No. 50Zdravlje
RUB 385 order
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Pharmacy24
- Spazmalgon 5 ml No. 10 solution for injection AT "Sopharma", Bulgaria
327 UAH. order - Spazmalgon 2 ml No. 5 injection solution AT "Sopharma", Bulgaria
130 UAH order
- Spazmalgon N10 tablets Balkanfarma-Dupnitsya AT, Bulgaria/Pharmaceutical and Chemical Industry, Zdravle AT, Serbia
30 UAH order
- Spazmalgon No. 20 tablets Balkanfarma-Dupnitsya AD, Bulgaria
48 UAH order
- Spazmalgon N50 tablets Balkanfarma-Dupnitsya AT, Bulgaria/Pharmaceutical and Chemical Industry, Zdravle AT, Serbia
117 UAH. order
