Compound
benzydamine hydrochloride as an active substance , as well as the following additional components: sodium chloride, trimethylacetylammonium-p-toluenesulfonate, povidone.
The vaginal solution contains benzydamine hydrochloride , as well as the following additional components: ethyl alcohol 96, purified water, trimethylacetylammonium para-toluene sulfonate, polysorbate 20, rose oil.
Release form and composition
Dosage forms:
- vaginal solution: has a characteristic scent of roses, transparent, colorless (in polyethylene bottles of 140 ml, 5 bottles in a cardboard box, complete with a guide nozzle and cannula);
- powder for the preparation of vaginal solution: white homogeneous granules, no foreign particles or lumps (9.44 g each in a polypropylene and paper sachet, 10 sachets in a cardboard box).
Each pack also contains instructions for using Tantum Rose.
Composition of 1 ml vaginal solution:
- active ingredient: benzydamine hydrochloride – 1 mg;
- additional components: rose oil, polysorbate 20, trimethylcetylammonium para-toluene sulfonate, 96% ethanol, purified water.
Composition of 1 sachet of powder:
- active ingredient: benzydamine hydrochloride – 500 mg;
- additional components: povidone, trimethylcetylammonium-p-toluene sulfonate, sodium chloride.
Pharmacodynamics and pharmacokinetics
The medicine belongs to the group of indazoles . This is a remedy that has anti-inflammatory, decongestant, antibacterial, antiseptic, antifungal and analgesic effects.
The active substance of the drug stabilizes cell membranes and inhibits the synthesis of prostaglandins . It also helps restore the integrity of the vaginal epithelium and contributes to its resistance to pathogenic effects .
The antibacterial effect is due to the rapid penetration of microorganisms through the outer membranes, destruction of their cellular structures and disruption of metabolic processes .
When used topically, it is well absorbed through the mucous membranes and penetrates into inflamed tissues. It is excreted primarily through the kidneys and intestines in the form of conjugation products or metabolites .
pharmachologic effect
The drug Tantum Rose has several effects:
- Antiseptic;
- Anti-inflammatory;
- Painkillers;
- Decongestant;
- Antibacterial;
- Antifungal.
The effect of the Tantum Rose solution is to restore the mucous membrane in the vagina, which improves its ability to resist pathogenic bacteria.
The drug Tantum Rose gets inside the cell of the causative agent of the disease, destroying its structure and disrupting metabolism.
Absorption occurs through the surface of the mucous membrane, since it is used topically. Excreted in urine and feces.
Indications for use
The medicine is used for:
- inflammatory diseases of the cervix, vulva and vagina;
- after radiotherapy ;
- fungal and trichomonas infections ;
- the need to prevent infectious complications in postpartum women;
- the need to accelerate reparative processes after childbirth;
- postpartum infections ( vulvitis , vaginitis and vulvovaginitis , etc.);
- the need to prevent post- and preoperative complications in surgical gynecology;
- inflammatory processes in the area of the uterine pharynx.
In addition, Tantum Rose is used after chemotherapy for tumors.
Side effects
Any negative manifestations occur extremely rarely and usually with prolonged therapy with Tantum Rose solution.
They occur in the form of local (more often) and systemic reactions:
- Irritations;
- Burning sensations;
- Drowsiness;
- Urticaria;
- Itching;
- Various skin rashes.
Photo gallery of side effects:
Drowsiness
Hives
Itching Burning sensation
Irritation
Skin rashes
Instructions for use Tantum Roses (Method and dosage)
The instructions for Tantum Rose indicate that douching takes place in a lying position. For a single procedure, use 140 ml. The liquid should remain in the vagina for several minutes.
For those who purchased Tantum Rose powder, the instructions for use indicate that the contents of the sachet should be dissolved in 500 ml of water. How to use the solution depends on the nature of the disease:
- for bacterial vaginosis, you need to use the medicine 1-2 times a day. The course is designed for 7-10 days;
- for the purpose of preventing post- and preoperative complications in surgical gynecology, as well as as a hygienic means after childbirth, douching is performed once a day. The course lasts 3-5 days;
- for vulvovaginitis and cervicovaginitis, the medicine is used 2 times a day. The course lasts 10 days.
The instructions do not indicate how to open the bottle. However, this point is difficult for many. Those who have already tried this product advise, first of all, to open the pink lid upwards, then pull the white pin all the way.
Reviews from women
Ekaterina, 36 years old : “At an appointment with a gynecologist, an inflammatory process was discovered. To get rid of it, I was prescribed Tantum Rose along with Klion. Everything has passed."
Maria, 21 years old : “I recommend this drug to everyone. I really like it and my friends also helped with various inflammations and thrush. Tested and approved by personal experience."
Alina , 26 years old : “I used Tantum Rose twice: against thrush and erosive inflammation. In the first case it helped 100%, and in the second it almost completely relieved the inflammation.”
Reviews of Tantum Rose
Reviews about Tantum Rose on the Internet can be found very contradictory. Someone was prescribed this drug by a doctor, and the medicine helped, while others did not even dare to use it because of the inconvenience of use. It is precisely because of the last factor that many women still try to buy analogues. Also, experts do not recommend using this remedy during pregnancy, but there are no direct contraindications to this.
In general, there are practically no categorical negative reviews about Tantum Rose, so this product is popular.
Cheap analogues substitutes
You can replace the drug using other means:
- Tantum Verde is produced in the form of lozenges based on benzydamine hydrochloride. (Italy).
- Tenflex is available in powder to create a solution. (Italy).
Photos of analogues:
Tantum Verde
Tenflex
Price Tantum Roses, where to buy
The price of Tantum Rose solution is usually about 700 rubles. Although in some places you can find this product at a much lower cost.
The price of Tantum Roses in powder form is also much lower - approximately 330 rubles. However, when using it, you need to spend time preparing the solution. So many women still prefer to buy a ready-made douche, despite the fact that the price of Tantum Rose in this case is noticeably higher.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Tantum Rose powder for vaginal preg solution.
500 mg 10 pcs.Angelini Francesco RUR 437 order
Pharmacy Dialogue
- Tantum Rose sachets 0.5g No. 10Angelini Francesco SpA
475 rub. order
- Tantum Rose 140ml No.5Angelini Francesco SpA
1105 rub. order
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special instructions
Long-term therapy is not recommended, as this may cause hypersensitivity reactions.
If there is no therapeutic effect after using the drug for the recommended period, you should consult a specialist.
Impact on the ability to drive vehicles and complex mechanisms
The use of Tantum Rose solution does not affect the ability to drive vehicles and does not interfere with activities that require high concentration and speed of psychomotor reactions.
Treatment safety
Despite the fact that the medicine is practically safe, there are points that deserve attention:
- If a woman uses the composition for a long time, the risk of irritation of the mucous membrane increases.
- If the desired effect does not occur within an adequate period of therapy, you need to consult a doctor and find an analogue.
- The active substance of the drug does not affect the functionality of the nervous system in any way, so it can be used before trips or especially important matters.
Important! It is allowed to perform procedures during pregnancy and lactation without special restrictions, if there are no medical contraindications for this.
Despite the over-the-counter availability of the medication and the absence of overdose symptoms, consult your doctor before starting treatment. Not all medications used in complex therapy combine well with the medicine. In this case, you should pay attention to analogues: Benzydamine, Tenflex. As for the reviews, they are positive. Patients confirm the effectiveness of the medicine in the treatment of thrush, vaginosis, and disease prevention. In addition, the composition is inexpensive and does not require restrictions on physical and mental activity. To understand how to use Tantum Rose, watch the video that shows the correct douching technique.
Buy Tantum Rose powder for vaginal solution 500 mg No. 10 in pharmacies
Vaginal solution TANTUM® ROSE
Registration number: ПN 014275/02
Trade name: Tantum® Rose
International nonproprietary name: Benzydamine
Dosage form: powder for the preparation of vaginal solution
Composition: For one sachet of powder for the preparation of vaginal solution 500 mg: Active component: benzydamine hydrochloride - 0.500 g Auxiliary components: trimethylacetylammonium-p-toluene sulfonate, povidone, sodium chloride
Description: Homogeneous white granules without lumps or foreign particles.
Pharmacotherapeutic group: non-steroidal anti-inflammatory drug
ATX code: G02CC03
Pharmacological properties
Pharmacodynamics: Benzydamine is a non-steroidal anti-inflammatory drug that belongs to the indazoles group. It has anti-inflammatory and local analgesic effects, has antibacterial, antifungal and antiseptic effects. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzidamine has an antibacterial and specific antimicrobial effect due to rapid penetration through the membranes of microorganisms with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes. Has antifungal effect against Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzydamine for inflammatory processes in the oral cavity, including infectious etiology.
Pharmacokinetics: When applied topically, the drug is well absorbed through mucous membranes and penetrates into inflamed tissues. Excretion of the drug occurs mainly by the kidneys and through the intestines in the form of metabolites or conjugation products.
Indications for use:
- in the postpartum period as a therapeutic and prophylactic agent for the prevention of postpartum infectious complications; - specific vulvovaginitis (in complex therapy) - nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy; - bacterial vaginosis; — prevention of postoperative infectious complications in surgical gynecology.
Contraindications: Hypersensitivity to any of the components of the drug.
Use during pregnancy and breastfeeding: There are no contraindications to the local use of the drug Tantum® Rose during pregnancy and lactation (breastfeeding).
Directions for use and dosage:
Intravaginally. Powder for preparing a vaginal solution 500 mg - the contents of 1 sachet are dissolved in 500 ml of boiled water. For one-time douching, use 140 ml of the resulting solution. The prepared solution can be stored for up to 5 days at room temperature. When repeated use, the solution must be warmed to body temperature. The procedure should be performed lying down, the liquid should remain in the vagina for several minutes. - in the postpartum period as a therapeutic and prophylactic agent to speed up the process of rehabilitation and prevent postpartum infectious complications: vaginal irrigation once a day for 3-5 days. - for bacterial vaginosis: vaginal irrigation 1-2 times a day for 7-10 days; — for nonspecific vulvovaginitis and cervicovaginitis of any etiology, including those secondary to chemotherapy and radiotherapy: 2 times a day for at least 10 days; — for specific vulvovaginitis, as part of complex therapy: 2 times a day for 3-5 days; — prevention of postoperative infectious complications in surgical gynecology: 1 time per day for 3-5 days.
Side effects: In rare cases, allergic reactions and dryness of the oral mucosa are possible.
Overdose: Currently, no cases of overdose of Tantum® Rose have been reported.
Interaction with other drugs: No clinically significant interaction of the drug Tantum® Rose with other drugs has been established.
Special instructions: Long-term use of the drug may lead to hypersensitivity. When using the drug for long periods, consult a doctor.
Effect on the ability to drive vehicles and machinery: the use of the drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
Release form: Powder for the preparation of vaginal solution 500 mg: 9.44 g of powder in a polypropylene paper sachet, thermally sealed; 10 sachets along with instructions for use are placed in a cardboard box.
Storage conditions: List B. At a temperature not exceeding 25° C. Keep out of the reach of children!
Shelf life: 5 years. Do not use after expiration date.
Conditions of release: Dispensed without a prescription.
Produced by “Aziende Quimique Riunite Angelini Francesco A.C.R.A.F. S.p.A.” / Aziende Chimiche Ruinite Angelini Francesco – ACRAFSpA Address: Viale Amelia 70, Rome, Italy / Viale Amelia, 70, Rome (RM), Italy
Organization receiving consumer complaints: Angelini Pharma Rus LLC Russia, 123001, Moscow, Trekhprudny per., 9, building 2 Tel.: +7 (495) 933 3590; Fax: +7 (495) 933 3951
Tantum® Rose: • Acts quickly: relieves itching, pain and irritation within 20 minutes after use[1] • Restores microflora, suppressing the growth of only pathogenic flora[2] • Allowed during pregnancy and lactation[3] References: 1. Czajka, R. et al. Assessment of the efficacy of benzydamine (Tantum Rosa) in the form of vaginal lavage in the treatment of perineal complaints in the early puerperium. Pol J Gyn Invest 2001; 4(2): 99-105 2. MaglianoE. At al. The role of benzydamine in the topical treatment of the so called non specific vaginitis. Int J Tiss React 1987; X1(2): 151-156 3. According to the instructions for use
Therapeutic effect of the drug
Benzidamine helps suppress the activity of the COX enzyme, as a result of which the concentration of pro-inflammatory mediators prostaglandins decreases and acts locally on the site of the pathological reaction, both during bacterial and fungal infection. This explains the therapeutic properties of the drug:
Composition and instructions for use of Sebozol shampoo
- Anesthesia;
- Reducing tissue swelling that appears due to increased permeability of vascular walls;
- Reduction of hypermia and redness in the mucous membrane and skin in the area of application of the drug.
In addition, Tantum rose is a solution that has low anesthetic properties and a high antiseptic effect, including against fungal infection. After the procedure of irrigation and douching, the active substance accumulates in the tissues of the focal lesion without being absorbed into the systemic bloodstream. Metabolism of the drug occurs in the liver, producing inactive breakdown products that are eliminated naturally.
