Tantum Rose - features of the use of all forms of the drug

Inflammatory diseases of the reproductive system are a common reason for visiting a gynecologist. After a thorough diagnosis and determination of the type of pathology, the doctor selects individual treatment. Among the products used are powders and solutions for douching. These include the well-known Tantum Rose, an anti-inflammatory local drug.

Release form and composition

Dosage forms:

• vaginal solution: has a characteristic scent of roses, transparent, colorless (in polyethylene bottles of 140 ml, 5 bottles in a cardboard box, complete with a guide nozzle and cannula);
• powder for the preparation of vaginal solution: white homogeneous granules, no foreign particles or lumps (9.44 g each in a polypropylene and paper sachet, 10 sachets in a cardboard box).

Each pack also contains instructions for using Tantum Rose.

Composition of 1 ml vaginal solution:

• active ingredient: benzydamine hydrochloride – 1 mg;
• additional components: rose oil, polysorbate 20, trimethylcetylammonium para-toluene sulfonate, 96% ethanol, purified water.

Composition of 1 sachet of powder:

• active ingredient: benzydamine hydrochloride – 500 mg;
• additional components: povidone, trimethylcetylammonium-p-toluene sulfonate, sodium chloride.

Medicinal properties

The mechanism of action of Tantum Rose is based on the suppression of the production of prostaglandin elements. Benzidamine makes the pathogen membrane permeable, entering the cell nucleus, it dissolves it from the inside, completely destroying the pathogen. As a result of the activity of the components, the surface layer of the epidermis becomes more resistant to infections. Thanks to this, accelerated scarring and tissue healing occur. Inflammation from erosive formations of the cervix goes away, regeneration begins due to inhibition of cyclooxygenases.

The medicine relieves swelling, pain, and eliminates the permeability of the vascular epithelium. Acts as an antiseptic that effectively affects strains of the Gardnerella group.

A high level of bioavailability is ensured by rapid absorption, which makes it possible to maximize therapeutic measures. Entering the tissues, the drug saturates them and the mucous membrane, exhibiting histoprotective properties.

Benzidamine is able to restore impaired microcirculation, reduce the concentration of biogenic amines, thereby reducing the level of pain sensitivity of the receptor system.

Participates in metabolic processes, is excreted through the kidneys and, partially, through peristalsis.

Pharmacological properties

Pharmacodynamics

Tantum Rose is a local non-steroidal anti-inflammatory drug that belongs to the group of indazoles. It has a local analgesic and anti-inflammatory effect, has antiseptic, antibacterial and antifungal properties.

The mechanism of action of benzydamine is based on the stabilization of cell membranes and inhibition of prostaglandin synthesis.

The substance has an antibacterial effect due to rapid penetration through the membranes of microorganisms, which subsequently causes damage to cellular structures, disruption of metabolic processes and cell lysis.

It has an antifungal effect against Candida albicans. Leads to structural modifications of the cell wall of fungi and the metabolic chains of mycetes, which prevents their reproduction.

Pharmacokinetics

When applied topically, benzydamine is well absorbed through mucous membranes and penetrates into inflamed tissues.

Excretion is carried out primarily by the kidneys and through the intestines in the form of conjugation products or metabolites.

Indications

Tantum Rose is prescribed for the treatment of inflammatory processes and gynecological diseases:

• Vaginal gardnerellosis, associated with a decrease in lactoflora and a sharp increase in anaerobic pathogens
• Inflammation of the vulvar and vaginal mucosa of various etiologies
• Pathologies associated with the treatment of oncological processes
• Cervicitis
• Thrush
• Prevention of infection before and after surgery
• Hygienic procedures during childbirth.

You can learn about the causes of burning sensation in the vagina from the article:

Tantum Rose, instructions for use: method and dosage

The drug is used intravaginally.

Method for preparing a solution from Tantum Rose powder: the contents of 1 sachet should be dissolved in 500 ml of water.

To carry out douching, a solution with a volume of 140 ml is used, pre-heated slightly in a water bath. The procedure must be carried out lying down, the solution should remain in the vagina for several minutes.

Recommended application:

• bacterial vaginosis (vaginal irrigation): 1–2 times a day for a course of 7–10 days;
• nonspecific vulvovaginitis and cervicovaginitis of any origin, specific vulvovaginitis (simultaneously with other drugs): 2 times a day for a course of 10 days;
• postpartum period (as a hygienic product) and complications in operative gynecology (prevention in the pre- and postoperative periods): once a day for a course of 3–5 days.

Indications for use

Tantum rose is used in the treatment of the following diseases:

• Bacterial vaginosis;
• Nonspecific cervicovaginitis and vulvovaginitis of various etiologies, incl. secondary developed as a result of chemotherapy and radiotherapy;
• Specific vulvovaginitis (as part of complex therapy).

The drug is also prescribed for the prevention of pre- and postoperative complications in surgical gynecology.

Tantum rose is used as a hygiene product in the postpartum period.

special instructions

Long-term therapy is not recommended, as this may cause hypersensitivity reactions.

If there is no therapeutic effect after using the drug for the recommended period, you should consult a specialist.

Impact on the ability to drive vehicles and complex mechanisms

The use of Tantum Rose solution does not affect the ability to drive vehicles and does not interfere with activities that require high concentration and speed of psychomotor reactions.

Tantum Rose - contraindications

Long-term clinical trials and studies have shown that the drug does not have a negative effect on the body. In this regard, there are practically no contraindications to its use. However, situations are possible when the drug negatively affects the patient’s condition and well-being. In this case, the medicine is discontinued and similar properties are used, but with a different composition. Tantum Rose can only be used during pregnancy if prescribed by a doctor. Among the contraindications to the use of the drug indicated in the instructions:

• individual intolerance;
• hypersensitivity to the drug.

Therapeutic effect, pharmacokinetics

Benzidamine, which is the main active component of the drug Tantum Rose, suppresses the activity of the enzyme cycloxygenase (COX), thereby reducing the concentration of pro-inflammatory mediators prostaglandins at the site of the pathological reaction. This determines the main therapeutic effects of this drug, which include:

• The analgesic effect is a reduction in the severity of pain in the area of ​​inflammation, the development of which is associated with the irritating effect of prostaglandins on sensitive nerve endings.
• Anti-edematous effect – reduction of tissue edema, which develops during inflammation due to increased permeability of vascular walls and the release of blood plasma into the intercellular substance.
• Reducing hyperemia (increased blood flow in inflamed tissues) and redness of the mucous membranes or skin in the area of ​​application of the drug.

Also, the drug Tantum Rose has a slight anesthetic effect (suppression of all types of sensitivity) and an antiseptic effect (destruction of pathogenic and opportunistic bacteria, viruses, fungi). After applying the drug to the mucous membranes, the active component accumulates well in the tissues of the inflammatory process. It can be absorbed into the systemic circulation in small quantities, after which it is metabolized in the liver to form inactive breakdown products, which are excreted primarily in the urine.

Price of the drug in pharmacies

The cost of Tantum Rose in powder form is relatively low. Its price is about 330 rubles. The finished solution is twice as expensive - about 700 rubles.

Similar drugs:

• Chlorhexidine bigluconate Concentrate for external use
• Lugol Solution for topical use
• Lugol solution with glycerin Solution for topical use
• Chlorhexidine bigluconate Substance-liquid
• Ioddicerinum Solution for topical use
• Tea tree DN Ointment for external use
• Lugol Oral Spray
• Miramistin (Miramistin) Solution for topical use
• Amol Oral solution
• Falimint Dragee

** The Drug Directory is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions. Do not self-medicate; Before starting to use the drug Tantum Rose, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace medical advice and cannot serve as a guarantee of the positive effect of the drug.

Are you interested in the drug Tantum Rose? Do you want to know more detailed information or do you need a doctor's examination? Or do you need an inspection? You can make an appointment with a doctor - the Euro lab is always at your service! The best doctors will examine you, advise you, provide the necessary assistance and make a diagnosis. You can also call a doctor at home . Euro lab clinic is open for you around the clock.

** Attention! The information presented in this medication guide is intended for medical professionals and should not be used as a basis for self-medication. The description of the drug Tantum Rose is provided for informational purposes and is not intended for prescribing treatment without the participation of a doctor. Patients need to consult a specialist!

If you are interested in any other drugs and medications, their descriptions and instructions for use, information about the composition and form of release, indications for use and side effects, methods of use, prices and reviews of drugs, or you have any other questions and suggestions - write to us, we will definitely try to help you.

Analogs

There are a number of compositions that are identical in properties to the functions and mode of action of Tantum Rose:

Tenflex

Abdi Ibrahim Ilac, Türkiye

Cost: R-or 0.15% 120 ml – 180-200 rub.

Spray 0.15% 30 ml – 230-250 rub.

A drug with analgesic, anti-inflammatory and antiseptic effects. Penetrates cell membranes, inhibits the synthesis of prostaglandins. By acting on the pathogen from the inside, it damages its structures, carrying out complete lysis of bacteria. Prevents the reproduction of candida strains that cause thrush. It is well absorbed through tissues and quickly covers the area of ​​inflammation.

Intended for the treatment of infections in the genital organs, with atrophy of the vaginal walls in old age. Also suitable for the treatment of diseases of the mucous membranes of the mouth and throat, for thrombophlebitis during pregnancy, for eliminating fungal and trichomonas pathogens. The method of use depends on the form. An undiluted solution is used as irrigation or tamponing in gynecology and phlebology; the spray is suitable for treating gums and throat.

The finished composition is a transparent green liquid in a polypropylene bottle with a screw cap. Spray - darkened brown glass bottles with a sprayer. The cardboard box is dark blue with a red stripe and a triangle in the center. The package contains 1 bottle and instructions. The solution has a pronounced smell and taste of mint.

Advantages:

• Can be used during pregnancy
• Suitable for use as part of combination treatment.

Flaws:

• May cause dry mucous membranes
• Not prescribed for children under 12 years of age.

Lactonorm

Lecco, Russia

Cost: Caps. No. 14 – 370-400 rub.

The drug contains bacteria that provide a destructive effect on a wide range of gram-positive and negative pathogens, including staphylococcus, Escherechia, and Proteus. The product normalizes metabolic processes and improves immunity. When introduced into the vagina, it restores the acid balance of the mucous membrane. The lactates released create negative conditions for infection.

The medication is intended for the treatment of vaginitis and vulvitis, bacterial manifestations. For therapeutic purposes, the method of use is to use 1 capsule twice every 24 hours for a week. For preventive measures, it is recommended to administer 1 time per day for 14 days. If necessary, the course can be extended.

The medicine is available in the form of intravaginal capsules, packaged in round plastic bottles of 14 units. They have a transparent shell filled with pale yellow granules. The box is white, cardboard, decorated with blue arcs at the corners. Contains 1 jar and instructions.

Advantages:

• High concentration of lactobacilli
• Can be used during pregnancy

Flaws:

• Inconvenience of insertion
• High price.

Salvagin

Emansi, Russia

Cost: Gel 5 ml No. 5 – 850-950 rub.

The drug restores the microflora, improves the condition of the mucous membrane during infections caused by pathogenic candida. Contains a citrobiotic of natural origin that suppresses the growth and reproduction of chlamydia, ureaplasma, gardnerella, trichomonas, and herpes virus. Inulin is a prebiotic that ensures the creation of normal lactoflora. Aloe extract helps eliminate pain, tissue regeneration, and rapid healing.

The drug is used for infectious vaginosis, colpitis of various etiologies. Prescribed to prevent infection after surgery and gynecological procedures. Used once a day for 5-7 days.

Available in the form of a gel, packaged in a tube with a protective tip and cap. To administer the medicine, it is necessary to break the seal and introduce all the contents into the cavity. The tube is made of polypropylene, placed in a cardboard box of a faint shade with pink stripes. Has a pleasant smell.

Advantages:

• Does not leak after use
• A simple treatment regimen.

Flaws:

• High price
• May cause a burning sensation.