Alcoholism is a serious problem that, according to statistics, affects every fifth family in the country. Alcoholism slowly but surely leads to gradual personality degradation.
Living in the same apartment with an inadequate person who is constantly on a drinking binge, makes scandals and drinks away his last money is very difficult.
Anti-alcoholism pills are one of the most common and effective methods of combating this problem.
Some drugs, for example Teturam , can be given to a drunkard secretly, without his knowledge.
This approach is appropriate in cases where the alcoholic does not want to be treated of his own free will and considers himself a normal person who “just drinks a little sometimes.”
Anyone who decides to try this drug needs to remember that, regardless of whether the alcoholic takes it of his own free will or not, you should always consult a doctor .
This is due to the fact that tablets can have a number of negative side effects, have many contraindications and, if used incorrectly, can cause serious harm to health.
Pharmacodynamics and pharmacokinetics
This drug blocks acetaldehyde dehydrogenase , which affects the biotransformation of ethanol , and also increases the content of acetaldehyde , a metabolite of ethanol , which provokes some unpleasant sensations: facial flushing, vomiting, tachycardia , nausea, malaise, decreased blood pressure . This leads to the development of a conditioned reflex reaction of disgust towards alcohol.
The maximum therapeutic effect is noticeable 12 hours after taking the drug and lasts for 10-14 days.
After using the product, absorption of the active substance from the gastrointestinal tract is about 80%. It is rapidly cleaved and reduced to dithiocarbamate . The drug is excreted in the form of glucurone conjugate or diethylamine and carbon sulfide , part of which is excreted through the lungs.
Peculiarities
If a patient takes Teturam and Warfarin tablets at the same time, then he needs to donate blood every week to monitor its clotting. Then the patient's dosage is changed. If he exhibits paresthesia symptoms (goosebumps running through the limbs), then the dose should be discontinued immediately.
Teturam directly affects psychomotor reactions, which means that the patient should not drive vehicles. In addition, he should not perform complex and responsible work, or come into contact with machinery. In general, he should not perform those activities that require high reaction speed and attention .
The day after drinking alcohol, Teturam should not be taken! First you need to remove intoxication and abstain from drinking alcohol for a whole day.
Indications for use
They take anti-drunkenness powder and pills. They develop a negative conditioned reflex to alcohol. However, the use of this drug can cause serious side effects, so it is prescribed only if other drugs do not work.
Before starting therapy, the patient is carefully examined. If there are no contraindications for use, the doctor explains how to take the drug and warns that drinking alcohol during treatment is dangerous.
This medicine can also be used as a detoxification agent in cases of chronic nickel poisoning.
Analogues of the drug
If necessary, the attending physician can use analogues of the drug.
You can buy at the pharmacy:
- Lidevin is a combination product containing B vitamins and disulfiram. It is used in narcology and psychiatry for the treatment of chronic alcoholism. The medication has a small number of contraindications and side effects. The drug is sold by prescription. The cost is 1800 rubles per package.
- Zorex is a drug produced in the form of capsules for oral administration. Contains unithiol and calcium pantothenate as active ingredients. The drug has a detoxifying effect on the breakdown products of ethyl alcohol, heavy metals and their compounds, as well as arsenic. The cost of the medicine is 195-277 rubles.
Also, if necessary, you can use drugs such as Antabuse, Esperal, Radother, Tempozil and some others as analogues.
Contraindications
You should not take the drug if:
- hypersensitivity to its active substance;
- diseases of the cardiovascular system at the stage of decompensation and compensation ;
- tuberculosis with hemoptysis;
- chronic obstructive pulmonary disease ;
- erosive lesions of the gastrointestinal mucosa;
- bleeding from the gastrointestinal tract;
- liver failure;
- epilepsy;
- diseases of the nervous system caused by infections;
- neuritis of the auditory and optic nerves;
- malignant tumors;
- residual effects after NMC ;
- suffered teturamic psychoses ;
- thyrotoxicosis;
- bronchial asthma;
- severe emphysema ;
- stomach and duodenal ulcers;
- renal dysfunction;
- diabetes mellitus;
- neuropsychiatric diseases;
- polyneuropathy;
- glaucoma;
- old age;
- childhood (up to 18 years);
- endarteritis;
- pregnancy;
- breastfeeding.
Short treatment regimen
Narcologists note that for patients who have consciously decided to quit drinking, therapy is much easier and more comfortable, and its effect is longer lasting, since there is a clear psychological message. For such patients, a three-week treatment regimen is recommended, involving only oral medication. The therapy goes like this:
| Stage | Duration of the stage | Daily norm | Single dose | Reception |
| I | 10 days | 450 mg | 150 mg | twice a day |
| II | 300 mg | three times a day |
It has long been proven that in 3 weeks you can develop a habit and get rid of it. Although alcohol addiction is a more complex biochemical attraction, with a strong desire and through medications, you can develop a tendency towards a healthy lifestyle. However, if a craving for alcohol appears or in case of relapse, a repeated therapeutic course of disulfiram is indicated.
Side effects of Teturama
During drug therapy, dysfunctions of the cardiovascular system, nervous system, liver, and gastrointestinal tract are possible, for example:
- metallic taste in the mouth, hepatitis ;
- polyneuritis of the lower extremities, memory impairment, headache , neuropsychiatric disorders, disorientation ;
- collapse , angina , edema , heart rhythm disturbances, myocardial infarction .
In addition, side effects of Teturam are likely in the form of allergic reactions ( skin itching , rash), as well as exacerbation of diseases that occurred in the past: gastritis , gastric and duodenal ulcers , thrombophlebitis , etc. With long-term use of the drug, acute psychosis , similar to acute alcoholic paranoid , alcoholic delirium , acute alcoholic hallucination . Hallucinatory syndrome can turn into paranoid , and paranoid into schizophrenia-like .
Dangerous consequences
If you take even one accidental sip of alcohol while using pills, then you need to be prepared for dangerous consequences. They are precisely the factor that restrains the desire to drink strong drinks, which means that if they are not taken well, it will not be possible to completely get rid of alcohol addiction. The worst thing is the inability to calculate the consequences, ignorance of the physical and mental resources of the body. The outcome can be anything – even death.
As you can see, it is extremely dangerous to give Teturam to patients without their knowledge.
Instructions for use Teturam (Method and dosage)
Before therapy, be sure to warn the patient about the consequences and possible complications. If Teturam tablets are prescribed, the instructions for use indicate that they should be taken orally. Dosage – 150-500 mg 2 times a day. The dosage regimen is individual.
After 7-10 days, a tetraalcohol test . After taking 500 mg of medication, take 20-30 ml of vodka. If the reaction is weak, the dosage of alcohol can be increased by 10-20 ml, but you can take no more than 100-120 ml of alcohol in total.
After 1-2 days in a hospital and 3-5 days on an outpatient basis , the test is repeated.
It is possible to adjust the doses of alcohol and the drug if necessary. The instructions for use of Teturama indicate that in the future you can take a maintenance dosage of 150-200 mg per day for 1-3 years.
What to do in case of acute alcohol poisoning?
Sometimes cases arise that a teturam alcohol test leads to intoxication. Then the person’s health sharply deteriorates, even to the point of convulsions. If such sensations last for several hours, then first aid should be provided. To do this, the patient is injected with 20 ml of methylene blue solution intravenously. Ephedrine, Lobelin are administered intramuscularly, and Camphor and Cordiamine are administered subcutaneously. In addition to this therapy, additional glucose is administered and the patient is given oxygen inhalation. For heart pain, the patient drinks Nitroglycerin , and for low blood pressure, Mezaton is administered intravenously.
Sometimes cardiac activity is so depressed that the patient is given a drip with Strophanthin. 0.5 ml of the drug is diluted in saline solution. Convulsions can be treated with an enema of chloral hydrate.
Interaction
It is not advisable to combine the medicine with:
- Isoniazid - possible disturbances in behavior and coordination;
- Phenytoin – a significant and rapid increase in the content of phenytoin in plasma with toxic manifestations is possible;
- derivatives of 5-nitroimidazole delirious disorders and confusion may appear
If an interaction between these drugs is necessary, clinical observation and monitoring of plasma drug levels is performed.
Teturam is used with caution in combination with:
- anticoagulants for oral of anticoagulants increases , the risk of bleeding is likely. It is recommended to monitor the content of active ingredients of drugs; it may be necessary to adjust their dosages;
- benzodiazepines – active substance Teturama can increase the sedative effect of benzodiazepines by blocking their oxidative metabolism . It is necessary to adjust the benzodiazepine according to the body's reactions;
- Theophylline - disulfiram inhibits its metabolism . The dosage of Theophylline should be changed depending on the body's reactions and the content of the active substance in the plasma;
- tricyclic antidepressants - increased reactions of intolerance to alcoholic beverages.
Release forms
Currently, the drug is produced in only one form - tablets. But at the same time, there are differences between the tablets in that the active component is contained in them in different dosages, since some tablets need to be taken orally, while others will be needed for implantation into the muscle or subcutaneous fat layer (in another way this is called “filing”).
All tablets have a flat-cylindrical shape, color - white or white with a yellow-greenish tint. If the tablets have a lower dosage, then on one of their sides there is a chamfer, that is, beveled edges. With a larger dosage, they are supplied with a mark, that is, a line drawn along the diameter. Available in packages containing thirty or fifty tablets.
Reviews about Teturama
Reviews about Teturama can be very different. This remedy helped some, while others could not even take it due to severe side effects. Negative reactions are usually reported by those who have taken alcohol; the consequences in this case can be sad. That is why you need to take this remedy under the supervision of a specialist. Reviews from doctors about Teturam indicate that it can be effective if used strictly according to the instructions. This should be done if other common remedies have not helped. And you certainly cannot give these anti-alcohol pills in secret from the person suffering from alcoholism. When taken, even a small amount of ethanol can lead to serious consequences for the body.
Thus, reviews of the tablets report that they will be effective if you use the medicine strictly according to the instructions, do not drink alcohol and are constantly monitored by a specialist.
How is hemming done?
on the person's skin . After this, the skin is pulled back and 8 Teturam tablets are injected, each weighing 100 mg. The incision is sutured and disinfected, and fixed with a bandage. After 2 days, these tablets dissolve and do not cause discomfort to the patient. The drug is deposited in adipose tissue, from where it will enter the bloodstream in small portions. After stitching, a tubercle may remain at the incision site, which forms after fibrosis of the skin.
Although filing has many advantages , it still has a drawback. This method can lead to polyneuropathy - damage to peripheral nerves. Therefore, the patient is additionally prescribed a vitamin B complex, for example, Neuromultivit. But if polyneuropathy progresses, then the tablets are removed from the skin.
Teturama price, where to buy
The price of Teturam is usually very affordable for consumers. Only the product from the Russian company ABVA-RUS has a high cost of 1,500 rubles. The price of Teturam from other manufacturers is approximately 50 rubles. You cannot buy or use this drug without a doctor's prescription.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Teturam tablets 150 mg 30 pcs. JSC Pharmstandard (ICN) Leksredstva Kursk
162 rub. order
show more
PaniPharmacy
- Teturam tablets Teturam tablets.
0.15g No. 50 Ukraine, Borshchagovsky Chemical Plant PJSC 61 UAH. order
show more
