Various drugs are used to treat alcohol addiction.
Each medicine has advantages and certain limitations for use. Among the safest options are homeopathic remedies.
One of these is Proproten-100 .
Pharmacodynamics and pharmacokinetics
When treated with Proproten-100, of the S-100 protein is modified , which couples metabolic and information processes in the brain. In addition, the synthesis of the neuronal membrane is normalized, modulating the synaptic plasticity of neurons. As a result, the functions of the brain structure are restored, the formation of alcohol dependence , the hypothalamus, and other things is eliminated. In patients suffering from alcohol dependence, the effect on positive emotional reinforcement is normalized, leading to a decrease in the frequency of self-stimulation of the lateral hypothalamus.
The activity of hippocampal neurons also decreases, the number of circulating immune complexes in the peripheral blood decreases, and a correlating decrease in ethanol consumption is noted. Taking Proproten-100 enhances the inhibitory effects of GABA in the central nervous system, restores neurotransmitter balance and conditioned reflex functions . At the same time, the brain's resistance to toxic influences and hypoxia .
Thus, treatment with this drug helps alleviate psychopathological disorders, for example: anxiety, mental stress, insomnia, irritability, anxiety, low mood, strong craving for alcohol . Therapy also allows you to reduce or completely eliminate somatovegetative disorders , manifested by: weakness, sweating, headaches, tremors, tachycardia, and digestive disorders . This drug is actively used to reduce or eliminate the symptoms of alcoholic “hangover” syndrome .
The anti-alcohol effect of the drug was also noted, reducing the craving for alcohol and reducing the likelihood of relapse.
Compound
The pharmacological agent is produced in the form of drops and tablets .
The basis of both forms is an active chemical compound – affinity-purified antibodies to the brain-specific protein S-100.
Drops
100 ml of medicinal solution contains 1.0 g of active ingredient.
For convenient use of liquid form in production, the following is also used:
- distilled water;
- ethanol.
Features of the preparation: the solution is administered in the form of a water-alcohol mixture, which contains up to 10-1991 ng/g of the active compound.
Packing is carried out in bottles (volume 25 ml).
Pills
In the process of manufacturing a tablet drug, in addition to the active substance, the following are used:
- lactose monohydrate;
- MCC;
- magnesium stearate.
Features of the preparation: applied to lactose in the form of a water-alcohol composition, which contains up to 10-1991 ng/g of the active compound.
Packing is carried out in blisters and cardboard boxes (20; 40; 50; 100 tablets).
Proproten 100: instructions for use (Method and dosage)
This medicine is intended to be taken orally, separately from food. The drug is prescribed in tablets one at a time, and drops 10 drops per single dose. It is recommended to keep the tablets in your mouth until they completely dissolve.
To relieve a hangover, the medicine must be taken every 30 minutes. in the prescribed single dosage.
For patients taking Proproten-100 drops, the instructions for the drug recommend that when sleep sets in, they resume taking it immediately after waking up. If a worsening of alcohol withdrawal symptoms is noted, then it is necessary to supplement treatment with other drugs that are usually used in detoxification.
When carrying out relapse prevention, it is assumed to take a single dosage of the drug of any form, 1-2 doses per day, for 2-3 months. Accidental consumption of alcohol requires an additional dose of double dosage 2 times a day.
Indications for use
Due to its ability to suppress the desire for alcoholic beverages and minimize the likelihood of relapse, Proproten-100 is used in the monotherapy of alcohol withdrawal syndrome, which occurs in mild or moderate severity.
The active substance alleviates psychopathological manifestations.
This helps eliminate:
- irritability;
- anxiety;
- Bad mood;
- strong craving for alcohol;
- mental stress;
- sleep disturbance.
The action of the active compound also extends to the somatovegetative function, which eliminates the characteristic symptoms of alcoholism:
- tremor;
- headache;
- tachycardia;
- sweating;
- digestive disorders;
- physical weakness.
Analogs
Level 4 ATC code matches:
Antaxon
Metadoxyl
Antabuse
Vivitrol
Naltrexone
Medichronal
Disulfiram
Teturam
Colma
Lidevin
Esperal
The main analogue of this drug for the active substance is Tenoten.
special instructions
Proproten restores the functions of the central nervous system, however, when taken, it is possible to develop a side effect - double vision. Recommendations from doctors taking the drug: if after treatment such a symptom does not develop within 2-3 days, you can engage in all types of activities that require increased concentration - operating complex mechanisms or driving vehicles.
Drops are not prescribed for the treatment of alcoholism in adolescents under 18 years of age, since there is no data on use in pediatric practice. No studies have been conducted on the effect of the active component on the course of pregnancy, so it is not prescribed to women “in a special condition.” In addition, it contains ethyl alcohol.
Combination with medications
No changes in the action of pharmacological agents were noted when the therapeutic course was supplemented with Proproten 100. Therefore, it can be combined with medications of all groups, without restrictions.
Precautionary measures
Dosage forms of a homeopathic drug do not prevent the development of intoxication, do not increase the severity of symptoms of intoxication, and do not cause intoxication when used together with alcohol. But it must be taken into account that it contains 25% ethyl alcohol. Therefore, for high-risk patients with a history of impaired renal and liver function, epilepsy, chronic alcoholism, drops should only be prescribed by a doctor.
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According to observations, if the drops are taken on the day of the feast, the patient drinks less alcohol than usual. The likelihood of a hangover or the severity of hangover syndrome decreases. There is no desire to recover from a hangover, and relapses occur extremely rarely.
If warning signs appear during treatment - headache, deterioration of condition, development of weakness - you should consult your doctor. If discomfort continues for 4-6 hours after the next dose, analogues are selected to continue the therapeutic course.
Reviews about Proproten-100
It should be noted that this drug is rarely discussed online. At the same time, reviews of Proproten-100 are of a different nature. Particularly noteworthy are the published results of the study, where each form of the drug was used to treat different patients. Thus, reviews of Proproten-100 drops show that this dosage form has a faster effect. However, reviews of tablets contain information about almost the same effectiveness as drops.
If we consider the results in detail, then approximately 50% of patients note an improvement in their health, 40% noticed a slight positive effect, for 6% of those examined, treatment with Proproten-100 was useless.
According to experts, to reduce the craving for alcohol, the sincere desire of patients to get rid of this craving is of great importance. As for this drug, many people experience a positive effect, but additional enhanced therapy is often required.
Restrictions on use
Despite the safety of the drug, the manufacturer warns of limitations in the annotation.
The use of a homeopathic product is prohibited if the following factors are present:
- allergy to substances included in the medication, as well as to lactose;
- childhood and adolescence (up to 18 years);
- pregnancy;
- lactation period;
- lactase deficiency.
Price Proproten-100, where to buy
In Russian pharmacies, the price of Proproten-100 drops varies between 190-250 rubles.
The price of Proproten-100 tablets is 100-270 rubles, depending on the number of tablets.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Proproten-100 drops for internal use.
approx. 25ml Materia Medica LLC 273 RUR order - Proproten-100 tablets homeopath. 40 pcs. Materia Medica LLC
RUB 269 order
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Interaction
Proproten-100 can be combined with pharmacological products of different effects.
The risk of the formation of hazardous chemical compounds is hypothetically eliminated.
When used simultaneously with alcoholic beverages, no negative reactions from the body are observed. This is due to the absence of substances incompatible with ethanol.
Side effects
Before starting therapy, it is important not only to learn how to take Proproten-100, but also to familiarize yourself with the list of possible side symptoms. The medicine may cause an allergic reaction in the patient or indigestion. If such symptoms appear, the drug should be discontinued. In rare cases, during treatment, accommodation disturbances and double vision appear. This symptom is a short-term condition that goes away in 5-10 minutes. Spasm of accommodation does not require treatment or discontinuation of the drug.
Alcohol compatibility
Proproten drops and tablets are used in the complex treatment of alcoholism. The result of the drug’s effect on the body is a significant reduction in cravings for alcohol. This helps the patient drink less alcohol and gradually get rid of the bad habit. In addition, Proproten reduces the severity of the hangover that appears the morning after drinking alcohol. Due to this, the risk of binge drinking is reduced. The medicine does not enhance the effects of alcohol on the body, but also does not prevent intoxication when consuming it.
