Pharmacodynamics
Pharmacological action - immunomodulatory, antiviral.
Preclinical and clinical studies have proven the effectiveness of the drug against influenza viruses, parainfluenza, herpes simplex viruses types 1 and 2 (labial herpes, genital herpes), other herpes viruses (varicella, infectious mononucleosis), enteroviruses, tick-borne encephalitis virus, rotavirus, coronavirus , calicivirus, adenovirus, respiratory syncytial virus (RS virus).
The drug reduces the concentration of the virus in the affected tissues, affects the system of endogenous interferons and associated cytokines, induces the formation of endogenous “early” interferons (IFN a/β) and interferon gamma (IFN γ). Stimulates the humoral and cellular immune response. Increases the production of antibodies (including secretory IgA), activates the functions of T-effectors, T-helpers (Tx), normalizes their ratio. Increases the functional reserve of Tx and other cells involved in the immune response. It is an inducer of a mixed Txl and Th2 immune response: increases the production of Txl (IFN γ, IL-2) and Th2 (IL-4, 10) cytokines, restores (modulates) the Txl/Tx2 balance. Increases the functional activity of phagocytes and natural killer cells (NK cells). Has antimutagenic properties.
Anaferon syrup - instructions for use
The manufacturer of the drug, Limited Liability Company, a scientific and production organization from Moscow, does not produce the immunostimulant in the form of syrup. Viral diseases in adults are treated with Anaferon tablets:
- On the first day of the clinic they drink 8 pieces - one every half hour.
- On the second – fifth day, the dose is three tablets.
- Then one tablet per day to maintain immunity.
Syrup to support immunity in adults – Ginseng tonic syrup from the Ecotsvet series. Use 10 ml of syrup per glass of water daily. Preventive course – from a month to six months. The product is contraindicated for children, pregnant and lactating women, people with hypertension, cardiovascular diseases, and mental instability.
Prevention of ARVI
For the treatment of ARVI in children under 3 years of age, it is more convenient to use the drop form. For prevention, Anaferon for children is recommended only in tablets, regardless of age. Preventive intake - 1 tablet per day (the tablet is dissolved in a tablespoon of water at room temperature).
For patients of the first health group, 40 days (2 packs) during the epidemic season are sufficient. For patients prone to frequent illnesses and in patients with chronic pathology, it is recommended to conduct repeated courses of 40 days each with an interval of 1 month or 90 days without a break and again after a month.
Anaferon drops - instructions for use
The oral solution is intended for the pediatric population. After 18 years of age, only sublingual tablets are offered. If desired, adults can use Anaferon children's drops by studying the instructions for use and reviews.
| Helps with colds | |
| 21.12.2018 14:43 | |
| Rating:5 | |
| Alesya | A week before the session, I was so exhausted that I felt the first signs of a cold. I went to the pharmacy, where I only had enough money for Anaferon drops for children. I read the instructions for use. I immediately measured out 10 drops into a spoon of water and drank 8 times every half hour, making a total of 80 drops in the first day. On the second day, I reduced the dose to 10 drops three times a day (30 in total) and continued to drink this until the fifth day. The impressions are good, the medicine has a pleasant taste and is easy to drink. She recovered in 5 days. |
| 18 years | |
| student |
| Advantages | Flaws | ||
| Budget price | Did not find | ||
| Speeds up recovery | |||
Indications
Anaferon for children is intended for the prevention and treatment of viral diseases:
- with the flu;
- with ARVI;
- with enterovirus, rotavirus;
- with herpes and frequent relapses;
- for chickenpox, sore throat, infectious mononucleosis, as a complex therapy;
- for the prevention of influenza during an epidemic;
- children who often catch colds;
- in the complex treatment of bacterial infections;
- with secondary immunodeficiency.
Anaferon price
Absorbable children's tablets Anaferon with instructions for use in children are sold at the price:
- a cardboard pack with a blister of 20 tablets for 200-250 rubles;
- plastic jar - 205-220 rubles.
The price for children's Anaferon with instructions for use in drops is kept at 250 - 275 rubles.
The average price of Anaferon tablets with instructions for use for adults is 205 rubles. In various pharmacies in Moscow, Anaferon can be purchased at prices ranging from 185 to 230 rubles per pack of 20 pieces. Minimum price for Anaferon in tablets and drops in the Dialogue online pharmacy network.
Anaferon during pregnancy
Based on the instructions for use and reviews from doctors, Anaferon for adults is not used in expectant and nursing mothers. The manufacturer refers to the lack of research on the use of the immunostimulant in pregnant women and during breastfeeding. For women during pregnancy and lactation, vitamin and mineral complexes are prescribed to combat viral infections:
- Pregnavite;
- Elevit Pronatal;
- Gendevit;
- Mom is complimentary.
Useful dietary supplements are taken an hour after lunch, one per day, with water. Supplements are contraindicated in case of individual intolerance to the ingredients of the complexes.
Compound
The drug, produced in drops, is intended for preschool children. Affinity-purified antibodies to human interferon gamma in an amount of 0.006 g (a mixture of three active aqueous dilutions of the substance, diluted 10012, 10030 and 10050 times, respectively) is the main ingredient of the drug. The composition also contains:
- maltitol - 0.06 g;
- anhydrous citric acid, anhydrous - 0.0002 g;
- glycerol - 0.03;
- potassium sorbate - 0.00165 g;
- purified water - up to 1 ml.
It is a clear liquid without sediment or color. Pharmacotherapeutic group: antiviral and immunomodulatory agent. ATX code: L03 and J05AX.
A darkened glass bottle serves as a container for packaging the drug with a volume of 25 ml. The dropper cap with first opening control tightly closes the neck. The packaging is a cardboard box, which contains instructions for use.
Important instructions
The main rule for taking Anaferon is to use the medicine immediately after the first symptoms of the disease appear. If you start using the medication as early as possible, the patient’s health usually improves within three days. If this does not happen, then consultation with a specialist is required. "Anaferon" for children can be used for prevention without worrying about the consequences and side effects. Scientific studies have been conducted on its safety and effect on the children's body. As a result, data were obtained on the inability of the drug to provoke negative phenomena, as well as cancerous tumors. It was information about the oncogenic nature of the drug that previously served as a reason for many doctors not to prescribe this medication.
Contraindications
A contraindication to the use of this drug is hypersensitivity or individual intolerance to its components.
The drug is contraindicated in children suffering from lactase deficiency, or glucose malabsorption syndrome, as well as a congenital form of galactosemia due to the presence of lactose in the composition.
Age up to 1 month.
Conditions of storage and sale
When purchasing this medicine, there is no need for a prescription. The drug is available for sale in most pharmacies throughout the country.
The price of 1 blister (20 tablets) is about 200 rubles.
Storage conditions are the same as for most medications: the room temperature should not exceed 25, it should not be exposed to direct sunlight. And should be kept in a place protected from children to avoid accidental use.
The drug is valid for 3 years from the date of production.
Active ingredients
"Anaferon" for the prevention of viral diseases has long found its use in pediatrics and the treatment of adult patients. The principle of action of the medicine is based on its active component, the amount of which varies depending on whether the medicine is produced in tablets or drops.
Thus, one pill contains 3 mg of affinity-purified antibodies to human interferon. The drops already contain 6 mg. Additional substances are also declared.
The tablet contains:
- lactose;
- magnesium stearate;
- microcrystalline cellulose.
The drops have a slightly different composition. The auxiliary components include:
- glycerol;
- citric acid;
- maltitol;
- potassium sorbate;
- water.
“Anaferon” is recommended for use by adults and children for the prevention of colds. However, first it is necessary to find out its effect on viruses.
Adverse reactions
If you do not exceed the dosage specified by the manufacturer, the occurrence of adverse reactions is almost impossible. The exception is children with individual intolerance to any component of the drug. If an allergic reaction or other unfavorable conditions occurs, you must stop taking Anaferon and consult a doctor to draw up a plan for further treatment or select another drug to strengthen the immune system.
There have been no cases of drug overdose in pediatrics. Even if the dosage specified by the manufacturer is accidentally exceeded, the drug is not capable of causing irreparable harm to the life and health of the child.
Anaferon analogues with instructions for use
Similar Anaferon analogues based on composition, price and instructions for use are presented in the table.
| A drug | Release form | For children | When we take | Price |
| Anaferon | tablets, drops | from 4 weeks | do not apply | 200-250 rub. for 20 pcs. |
| Aflubin | tablets, drops | from the first days | carefully | 280-330 rub. for 12 pcs. |
| Kagocel | pills | from 36 months | do not apply | 200-250 rub. for 10 pcs. |
| Ergoferon | tablets, oral solution | from 36 months | do not apply | 280-350 rub. for 20 pcs. |
| Viferon | gel, ointment, suppositories | from the first days | from the 14th week | 239-882 rub. for 10 pcs. |
| Arbidol | tablets, capsules, powder | from 24 months | do not apply | 450-480 rub. for 20 pcs. |
| Grippferon | nasal drops and spray | from the first days | Maybe | 333-450 rub. for 10 ml |
Instructions for use of Anaferon analogues and consumer reviews indicate that in terms of price-quality ratio, Anaferon is a leader among immunostimulating drugs.
Impact on the body
Due to the active immunomodulatory and antiviral effect of Anaferon, it is advisable to use this medication to speed up the healing process and prevent viral pathologies.
The active ingredient is active against:
- adenovirus;
- influenza and parainfluenza virus;
- rotavirus;
- herpes.
The drug also actively eliminates the manifestations of respiratory diseases. Once in the body, the active substance quickly reduces the level of viral microparticles in organs and tissues, as a result, the disease quickly recedes because the patient’s own interferons multiply in the blood. The drug increases the activity of macrophages, helps induce antibodies against viruses and stimulates the cellular response to the invasion of pathogenic particles. However, to date there are no available chemical studies that would reveal the full cycle of the drug’s effect on the body, starting from absorption in the stomach and ending with its complete elimination. Therefore, the manufacturer does not provide complete data on the pharmacological characteristics of the drug’s effect on the body.
Action
The drug (in both forms of release) has an antiviral, strengthens the body's defenses, and immunomodulatory effects.
The drug has shown effectiveness in treating:
- herpes viruses;
- enteroviruses;
- parainfluenza;
- flu;
- rotovirus;
- viruses caused by tick-borne encephalitis;
- adenovirus;
- caliciviruses;
- coronaviruses.
Taking the drug promotes a cellular and humoral immune response to the appearance of viruses in the body - their concentration decreases, and the production of cytokines and interferons increases.
"Anaferon" can be taken together with other drugs of different pharmacological groups. No cases of incompatibility were recorded.
Replacement for antibiotics. Possible or not
The ability to use Anaferon for prevention is based on the ability of the drug to stimulate the patient’s own immunity. As a result, the patient’s body more actively fights the viral particles that have penetrated inside. However, the active substance is not capable of destroying pathogenic microorganisms and does not affect their ability to reproduce. The effect of the drug is based on immunomodulatory properties and increasing the body’s ability to fight the disease, but these tablets cannot replace antibiotics. Therefore, when a doctor prescribes antibacterial therapy, you should not rely on the use of Anaferon, which belongs to the category of homeopathic drugs.
