pharmachologic effect
The use of Aurobin leads to increased tone and decreased permeability of the vascular walls of the rectum, therefore it is successfully used to treat diseases of the anorectal area.
The pharmacological action of Aurobin is determined by the active ingredients included in its composition: prednisolone capronate, lidocaine, dexpanthenol, triclosan
Prednisolone relieves inflammation and has an antiallergic effect, lidocaine eliminates burning and pain, and acts as a local anesthetic. Dexpanthenol helps restore the affected mucosa and epithelium. Triclosan in Aurobin acts as an antiseptic that affects fungi and bacteria.
Analogs
Currently, there are no analogues of aurobin with the same active substances. The drug can be replaced with drugs with a different composition, but with similar indications.
Among them are:
relief,- hemorrhoids,
- pilex,
- posterized,
- ichthyol,
- betiol,
- proctane,
- anusole,
- proctosedyl.
Contraindications
According to the instructions, Aurobin is not prescribed to children under the age of one year, with viral, bacterial, fungal infections of the skin, with intolerance to the components of the ointment, with the simultaneous use of lidocaine in connection with other diseases.
Do not use Aurobin ointment in the periorbital area for the treatment of eye diseases.
Aurobin is also not prescribed during breastfeeding or pregnancy (in the first trimester). In the second and third trimesters of pregnancy, Aurobin can be prescribed, but only for special indications.
Instructions for use
The official instructions for the use of Aurobin ointment regulate the possibility of external and rectal use only.
Before applying the drug, hygiene procedures are carried out and the mucous membranes are dried. The ointment is applied to external hemorrhoids in a thin layer, without rubbing onto the mucous membranes.
When treating hemorrhoids inside the rectum, the ointment is used for rectal administration. Before administration, you should empty your intestines. A pea-sized amount of the drug is injected into the rectum.
In the acute period, the product is used 3-4 times a day, after passing the most acute phase - 1-2 times. The required course of treatment is 5-7 days.
The possibility of using the ointment for children over 1 year of age, as well as the required course and dose, are determined by the doctor, based on the need and possible risks.
For some diseases and for elderly patients, the dose and course are reduced, 1-2 times a day is allowed.
For patients of any age and health status, it is necessary to strictly follow the recommended frequency and duration of use of the drug; applying it to a large surface is unacceptable.
Release form and composition
The drug is packaged in aluminum tubes of 20 g and packed in boxes. Aurobin is a homogeneous white ointment with almost no odor.
The medicine combines several active components, which provide effective elimination of all symptoms of hemorrhoids:
- Prednisolone is a glucocorticosteroid (GCS) that has a local anti-inflammatory and antiallergic effect. Reduces swelling, relieves itching, and reduces the permeability of the walls of small vessels.
- Lidocaine - has a local anesthetic effect, eliminates pain and itching.
- Dexpanthenol – improves regeneration processes, accelerates local metabolism, and has an anti-inflammatory effect.
- Triclosan is an antiseptic component that has an inhibitory effect on pathogenic flora - fungi and bacteria.
The composition of 1 g of the drug includes:
- Prednisolone capronate – 2 mg;
- lidocaine hydrochloride – 20 mg;
- dexpanthenol – 20 mg;
- triclosan – 1 mg;
- binding components - liquid paraffin, glycerol, dimethicone, purified water, propylene glycol and others.
In this drug, the active ingredients interact well and enhance the overall pharmacological effect, complementing each other.
Side effects of Aurobin
Aurobin can cause local side effects: burning, dryness, increased sensitivity and thinning of the skin, irritation, poor wound healing. Judging by the reviews, Aurobin, with long-term use, can cause local hirsutism, purpura, hypertrichosis, acne, fungal infection, folliculitis, hypopigmentation, telangiectasia, skin atrophy, diaper rash, allergic contact dermatitis.
When applying Aurobin ointment over a large area, the manifestation of Itsenko-Cushing syndrome, hyperglycemia, increased blood pressure, hypokalemia, glucosuria, and increased intracranial pressure (benign) is possible.
With prolonged use of Aurobin over a large area, bradycardia may develop due to the systemic effect of lidocaine.
Indications for use
The drug aurobin is effective not only for acute hemorrhoids, but also in the treatment of the following diseases of the anus and their symptoms:
- eczema and dermatitis;
- itching, anal fistula;
- anal fissures;
- psoriasis;
- neuroallergic skin disease in the perineal area.
Mode of application
The drug is used externally and rectally. Adult patients should apply aurobin with clean hands in a thin layer to a previously cleaned affected area, with a frequency of application 2-4 times a day.
Children under 12 months of age are prohibited from using the drug.
If symptoms decrease, the dosage may be reduced in consultation with your doctor. The maximum duration of treatment is set to 7 days. Improvement is usually noticeable after 5 days of treatment.
Release form, composition
Aurobin is available in the form of a white ointment without a distinct odor in a 20g tube.
The effectiveness of the drug is due to the combination of its components, such as:
- prednisolone (a hormonal corticosteroid that allows you to effectively and quickly stop the process of inflammation in the affected area, and also has an antiallergic effect);
- lidocaine (a powerful anesthetic that eliminates itching, burning and pain, eliminating the need for various painkillers);
- D-panthenol (stimulates the rapid restoration of tissues and the outer layer of the mucous membrane, primarily suffering during the acute phase of inflammation);
- triclosan (has antibacterial, antimicrobial and antiseptic effects, which makes Aurobin ointment superior to many analogs in the treatment of diseases of the anal and perianal areas).
1g of aurobin contains:
- Prednisolone capronate – 2 mg;
- lidocaine hydrochloride – 20 mg;
- D-panthenol – 20 mg;
- excipients (triclosan, glycerol, macrogol stearate, liquid paraffin, cetyl alcohol, etc.).
Interaction with other drugs
Given the composition of this drug, you should refrain from using other drugs containing lidocaine. The likelihood of an acute overdose is low, but with improper or prolonged use, side effects are possible, implying the systemic effect of the glucocorticosteroid (suppression of the function of the adrenal cortex), as well as disturbances in heart rhythm due to the action of lidocaine.
Reviews
- “The drug Aurobin combines several active components and has a combined effect, therefore it is convenient in the treatment of hemorrhoids complicated by allergic reactions. Well tolerated by patients. Because of GCS, use is necessary in a short course and under the supervision of a doctor.” Proctologist.
- “Effectively replaces the simultaneous use of several means. It has proven itself excellent in the treatment of anal fissures, exacerbation of hemorrhoids, and postoperative recovery. When used correctly, I did not observe any side effects.” Proctologist.
- “Aurobin has a pronounced rapid effect and does not require long-term use. It relieves swelling and pain in the perianal area, heals cracks and postoperative wounds. Good balance of price and quality. One package is enough for a full course of treatment. Available in pharmacies all the time, patient reviews are positive.” Doctor.
- “During an exacerbation of hemorrhoids, I was prescribed Aurobin. After 2 days of use, rashes appeared, the mucous membranes burned like fire. I had to give up the ointment and prescribed another one. I try not to use hormonal drugs anymore.” Anna.
- “I work as an accountant, I sit at the computer all the time. I don’t lead an active lifestyle; at home I also spend all my time watching TV. I gave myself hemorrhoids. For a long time I treated myself with suppositories; I didn’t want to go to the doctor. But she got to the point where she could no longer walk or sit. The doctor prescribed Aurobin ointment, I felt so bad that I decided to use a hormonal drug. After 3 days of treatment, the nodes became smaller and the pain went away. My condition and mood have improved. I was treated for 5 days, I think I have recovered. The ointment helped me." Natalia.
- “Aurobin helps cure hemorrhoids much better and faster than suppositories.” Inna.