Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The drug, containing a large list of micro- and macroelements, compensates for the lack of microelements and minerals, takes part in the regulation of metabolism and their metabolism. They are part of the cellular contents in the form of cofactors of many enzymes, ensuring the vital activity of cells, stabilizing the structure of non-enzymatic macromolecules, vitamins and hormones . In case of a lack of microelements in a healthy body as a result of an unbalanced diet, in old age and adolescence, during pregnancy and lactation, recovery from diseases of various origins, the drug is extremely effective and normalizes the condition of the body in the shortest possible time.
Pharmacokinetics
No data.
Other information:
Use internally during meals. Add a single dose of drops to 50 ml of liquid (for example, water, fruit juice, syrup, fruit tea). It is not recommended to take the drug with milk or coffee, as this impairs the absorption of its active ingredients.
Registration certificate:
No.UA/9101/01/01 dated 04/04/2019
BEFORE USE, CONSULT A DOCTOR AND READ THE INSTRUCTIONS! The material was downloaded from the site www.beres.ua . The information on the website www.beres.ua is of a general nature and is for informational purposes only. Although BERESH PHARMA CJSC carefully monitors the content of the site, we cannot guarantee that the information provided does not contain inaccuracies or is not out of date. Therefore, if you find errors on this site, we ask you to notify us: [email protected]
Indications for use
- In complex therapy and prevention of mineral metabolism disorders due to malnutrition against the background of chronic alcoholism , diets, diabetes mellitus , during pregnancy and lactation, high physical activity;
- With increased fatigue, weakness, insomnia , poor appetite, during the period of convalescence after serious illnesses, reduced immunity , with degenerative processes in the osteoarticular system, menopause , during antibiotic therapy, radiation and chemotherapy .
Pharmacological properties of the drug Beresh Plus Drops
The drug contains an aqueous solution of mineral compounds and trace elements with the help of coordination bonds included in the molecules of organic substances. Microelements play an important role in maintaining the biological balance of the body. Most of them are contained in cells mainly in the form of co-factors of enzymes, ensuring their catalytic activity, play a role in stabilizing the structures of non-enzymatic macromolecules, and maintaining the level of vitamins and hormones in the human body. Deficiency of microelements can also be observed in healthy individuals, for example, in certain age periods (adolescence, old age and senility), or in special physiological conditions (pregnancy and lactation), during periods of increased need for them. Some diseases and therapeutic interventions also lead to the development of micronutrient deficiency, which in turn can manifest itself in a variety of clinical symptoms. Even a slight deficiency of microelements can have an adverse effect on the immune status, physical and general condition of the body, especially during the period of convalescence after illness and surgical interventions. Beresh Plus drops contain most of the essential microelements. The purpose of using drops is to supply the body with the required amount of microelements, sufficient to ensure the biochemical processes that depend on them, namely:
- iron affects the formation of hemoglobin and a number of enzymes, RNA metabolism, and is necessary to maintain immune status;
- zinc affects the function of enzymes involved in hematopoiesis and amino acid synthesis, the activity of the pancreas and gonads, immune status, and reproductive function;
- magnesium is necessary for normal activity of the myocardium and skeletal muscles, antioxidant protection, formation of bones and teeth, protein, carbohydrate and fat metabolism, and the functioning of nervous tissue;
- manganese affects reproductive function, the formation of bone and cartilage tissue, and the body's antioxidant defense;
- copper affects the immune status, antioxidant defense of the body;
- vanadium and nickel normalize the cholesterol content in the blood serum, an increased level of which is an important risk factor for the development of cardiovascular diseases;
- boron is involved in the metabolism of calcium, magnesium and phosphorus, and in the formation of bone tissue.
Beresh Plus drops increase the body's nonspecific resistance to various diseases. The drops are non-toxic when taken long-term and do not have embryotoxic or teratogenic effects. Pharmacokinetics. The active ingredients of the drug Beresh Plus Drops are well absorbed in the gastrointestinal tract, this ensures the digestibility of microelements. Pharmacokinetic studies were carried out on dogs using isotope compounds. The deposition of microelements 72 hours after administration indicates that among the active ingredients of the drug Beresh Plus Drops:
- iron is absorbed in particularly significant quantities (about 30% of the content);
- zinc, cobalt and molybdenum are absorbed in significant quantities (about 5, 6 and 4% content);
- manganese and nickel are absorbed in less significant quantities (about 2 and 1% content).
Beresh Plus, instructions for use (Method and dosage)
It is recommended to take Beresh Plus drops during meals, together with vitamin C in a dosage of 50-100 mg, and be sure to drink at least 200 ml of liquid. You can drink it with water, juice, compotes, fruit tea.
For the purpose of prevention and treatment, the drug Beresh Plus is prescribed in a dosage of 1 drop per 2 kg of body weight per day, which is taken in 2 doses. The effect of the drug appears after 1-1.5 months of continuous use. According to indications, a repeated course of treatment is possible. The drug Beresh Plus is prescribed to children in the same dosage, starting from the age of two.
Dosage:
In case of prophylactic use: For body weight 10-20 kg - 5 drops 2 times a day. With a body weight of 20-40 kg - 10 drops 2 times a day. For body weight over 40 kg - 20 drops 2 times a day. In case of use for the treatment of conditions listed in the indications: With a body weight of 10-20 kg - 10 drops 2 times a day. With a body weight of 20-40 kg - 20 drops 2 times a day. For body weight over 40 kg - 20 drops 3 times a day. When used to improve the general condition and well-being of patients with cancer whose body weight exceeds 40 kg, on the recommendation of a doctor, daily doses exceeding the above, but not more than 120 drops per day, can be used. In such cases, it is recommended to divide the daily dose into 4-5 doses in equal parts.
Price for Beresh Plus, where to buy
The price of Beresh Plus drops in a 30 ml bottle varies between 150-168 rubles per package; 100 ml - 465-487 rubles. You can buy Beresh Plus in almost all pharmacies in Moscow.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
Pharmacy Dialogue
- Beresh Plus (bottle 100 ml) Beresh
489 rub. order
show more
Pharmacy24
- Beresh plus 30 ml drops ZAT "Beresh Pharma", Ugorshchina
123 UAH. order - Beresh plus 30ml No. 4 bottles of oral drops ZAT "Beresh Pharma", Ugorshchina
402 UAH order
- Beresh plus 100 ml drops ZAT "Beresh Pharma", Ugorshchina
320 UAH. order
Release form
The medicine is available in dark glass bottles with a convenient dispenser and an airtight lid. You can buy containers of 30 and 100 ml at the pharmacy. The drug is sold in cardboard packaging along with instructions for use.
Drops should be stored in a cool place. The air temperature should not exceed 25 degrees. Sales period is 4 years from the date of manufacture.
After unsealing the product, the contents of the bottle can be used for six months. Available without a prescription. Country of origin: Hungary.
Stock
active words: 1 ml (18 drops) containing: molybdenum 0.1902 mg (in the form of ammonium molybdate tetrahydrate 0.35 mg);
vanadium 0.1219 mg (for example, ammonium monovanadate 0.28 mg); boron 0.1049 mg (in the form of boric acid 0.6 mg); cobalt 0.0248 mg (see cobalt (II) chloride hexahydrate 0.1 mg); midi 0.2545 mg (in the form of midi sulfate pentahydrate 1 mg); zaliza 2.009 mg (in the form of zaliza (II) sulfate heptahydrate 10 mg); magnesium 0.4044 mg (in the form of magnesium sulfate heptahydrate 4.1 mg); manganese 0.3055 mg (in the form of manganese sulfate monohydrate 0.94 mg); nickel 0.1087 mg (in the form of nickel (II) sulfate hexahydrate 0.4865 mg); fluoride 0.0904 mg (in the case of sodium fluoride 0.2 mg); zinc 1.137 mg (in the form of zinc sulfate heptahydrate 5 mg);
additional speeches:
glycerin (85%), disodium edate, glycine, succinic acid, ascorbic acid, tartaric acid, sodium-potassium tartrate, sulfuric acid, purified water.
Medicine form. Oral droplets
.
The main physical and chemical properties:
vision, water distribution of light green or yellowish green color, without siege.
Pharmacotherapeutic group. Other preparations of minerals. AT code
X
A12C X.
Prevention using the drug
The drug is very useful as a prophylactic agent to prevent the development of an imbalance of microelements. It is important to consider that the doses of drops used for prophylaxis should be less than the doses used for therapy.
The required dosage should be calculated taking into account the patient’s body weight, but in this case one drop should be taken for every two kilograms. It is recommended to divide the dose obtained through such calculations into a couple of doses.
The parallel use of ascorbic acid in amounts up to 100 mg will improve the absorption of the medication, which will also strengthen the immune system.
When taking Beresh Plus, experts recommend adhering to some simple rules. Do not use milk or coffee to dilute the drug. These liquids significantly impair the absorption process of the active components contained in the drops.
In some cases, when adding drops to tea, you can observe its sharp darkening. This is due to the chemical reaction of the components of the drug with tannic acid contained in some types of tea. This reaction is normal and does not affect the therapeutic properties of the medication. Adding a small amount of ascorbic acid or lemon will help return the drink to its natural color.
Side effects
Even rarely, if you take the drops lightly, or with less, as recommended below, mild and temporary side reactions may appear, as indicated below.
On the side of the scolio-intestinal tract:
Saline-intestinal disorders, including mild fatigue, abdominal pain, constipation, bitter taste in the mouth, congestion of dental enamel in children, which do not require stagnation of any visits and quickly pass.
On the side of the immune system:
hypersensitivity reactions.
Negative Impacts
As the instructions for Beresh Plus drops indicate, negative effects develop extremely rarely against the background of their use. However, the possibility of their development still exists. Most often, patients note the development of allergic manifestations when taking drops, accompanied by skin rash, irritation, redness, and swelling. In rare cases, discomfort and pain in the abdomen are noted.
This is confirmed by the instructions and reviews for the drug “Beresh Plus”.
Experts attribute this negative manifestation to the fact that patients take the drug on an empty stomach or use too little liquid. If any negative reactions develop, the patient is advised to stop taking the drug and consult a doctor.
Interactions with other medicinal drugs and other types of interactions
An interval of at least 1 year must be maintained between taking the drug Krapli Beresh Plus® and taking other medications. To avoid overdose or antagonistic interactions, do not combine the drops with other drugs at the same time to remove microelements.
Between stagnant medicinal preparations, including penicillamine, bisphosphonates, fluoroquinolones, tetracyclines, and stagnant medicinal preparations, Krapli Beresh Plus® may take 2 years (inheritance of physico-chemical The interactions may change due to the absorption of the drug).
It is not recommended to take the drug at the same time with milk or coffee, as this may result in the absorption of liquid liquid.
When antacid drugs are ingested for one hour, in addition to aluminum, calcium, magnesium, the absorption of the drug decreases.
Features
of stagnation.
Sowing with milk or any other product is not recommended for those in which the soaking of active substances occurs. When the drug is added to the song, the appearance of tea may darken. This product is safe and is used instead of tannin (tannic acid) that is added to tea. When adding a few drops of lemon juice, lemon juice substitute or ascorbic acid, the infusion is not created.
Suspension during pregnancy and breastfeeding
During pregnancy and breastfeeding, medication can be taken at the recommended dosage (after consultation with a doctor).
The importance of influencing the fluidity of the reaction during treatment with vehicles or other mechanisms
When taken in recommended doses, no negative effects are to be avoided.
Showing
Deficiency of microelements or pathological conditions, if necessary, additional stagnation of mineral substances:
- to support the activity of the immune system, the vitality of the body, and during periods of decreased vitality, such as colds and flu;
- in case of insufficient food (for example, special diets, including weight loss diets, vegetarian food), as well as in case of increased physical activity;
- in case of increased nausea, lack of appetite, bloat, weakness, sleeplessness, as well as for rapid rehabilitation after illness, surgical procedures;
- as an additional therapy for the improvement of inflammation and self-esteem of patients with cancer.
Contraindications for use
According to the instructions for use for Beresh Plus, there are several situations in which doctors advise not to use the medication. Drops should not be taken:
- If the patient's body weight is less than 10 kg.
- If the patient is under 2 years of age.
- If the patient has severe renal failure.
- For hemochromatosis, Westphal-Wilson-Konovalov disease, hemosiderosis, and other pathologies associated with disturbances in the metabolic processes of iron and copper.
- In case of increased hypersensitivity to any of the components contained in the drug.
The lactation period and pregnancy are not contraindications to taking the medication. In this case, no dose adjustment is even required. However, before starting to use the medication, it is better for a woman to consult a doctor.
