Neurologists at the Yusupov Hospital, after examining patients using the latest imported equipment, if there are indications and no contraindications, prescribe Ceraxon to patients in a solution for injection or oral administration. Pharmacies have Ceraxon packaged in sachets. These are bags of bulk medicine from which a suspension is prepared. One sachet (sachet) contains 1000 mg of the main active ingredient - citicoline. 6 or 10 sachets are placed in a cardboard box along with instructions for use of the drug.
Doctors individually choose the dose and form of the drug. Medical personnel teach patients and their relatives how to prepare a suspension from the powder. Severe cases of diseases requiring the appointment of Ceraxon are discussed at a meeting of the Expert Council. Candidates and doctors of medical sciences, doctors of the highest category take part in its meeting.
Release form and active components in the composition
In the pharmacy chain, the nootropic "Ceraxon", the instructions for use confirms this, is presented in various forms:
- for oral administration - liquid solution;
- for injection solution - in transparent glass ampoules;
- oblong, coated tablets.
The active component of the drug is Citicoline. It has nootropic effects.
The solution for injection delivery of the drug may contain 500 or 1000 mg of the active component. Among the auxiliary components, the instructions indicate: sodium hydroxide and hydrochloric acid, as well as water for injection. In a consumer box, the product in a volume of 4 ml is packaged in cellular packaging, 5 pcs. in each.
The solution for oral administration is presented in bottles of 30 ml, with the active substance 10 g. The consumer pack contains 1 bottle.
If you purchase a tablet form of the medicine, then each tablet contains 500 mg of Citicoline, as well as excipients that enhance the pharmacological properties of the main component. In the pharmacy pack they are presented in protective blisters of 20 pcs.: 5 pcs. in one blister.
special instructions
Small crystals may form in small quantities in the oral solution. This is due to preservatives that can trigger the crystallization process. When stored correctly, they dissolve over time, and their appearance does not affect the quality of the drug.
When taking Ceraxon, it is necessary to avoid activities associated with a high concentration of attention (driving a vehicle, working with dangerous mechanisms). This is due to a decrease in the reaction rate when using the drug. After the course of treatment everything returns to normal.
Doctors in reviews of the drug "Cerakson" note the following positive qualities.
- It is effective in complex therapy of chronic and acute forms of circulatory disorders in the brain of the head.
- It has a restorative function of cell membranes, and because of this reduces damage to brain tissue.
- An effective and affordable drug, it can be purchased at every pharmacy.
- The drug is well tolerated, and side effects rarely occur.
- The drug "Ceraxon" has many forms, this makes therapy easier.
- Used for many neurological diseases.
- The drug has a large evidence base (it has been well studied).
Many doctors do not see any bad qualities in Cerakson, except for the high cost.
Pharmacological properties
Since the drug "Ceraxon", which helps with pathologies of brain activity, is a representative of a subgroup of nootropics, it is characterized by their pharmacological effects on the human body:
- actively restores cell membranes that are already damaged;
- optimally corrects cholinergic transmission in neurocytes;
- significantly reduces the negative manifestations of neurological manifestations;
- reduces the duration of coma of post-traumatic origin;
- prevents the release of negative radicals in tissues as much as possible;
- capable of inhibiting the effects of phospholipases;
- best reduces the amount of brain injury caused by strokes.
The remedy has also found its use in the treatment of motor and sensory disorders in neurological practice - of various origins. According to the instructions, the medication “Cerakson” 1000 mg, the instructions for use indicate this, is very effective in correcting the following neurological conditions:
- existing difficulty in performing self-care procedures;
- lowering memory parameters.
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Analogues and cost
Currently, there are several analogues of Ceraxon in 1000 mg sachets.
These include:
- “Tanakan”, “Cogitum”, “Nooclerin”, “Nootropil” - solutions for oral administration;
- “Ginkoum”, “Neuromet”, “Fezam”, “Vinpotropil”, “Noben” - capsules;
- “Omaron”, “Vincetin”, “Ginos”, “Acefen”, “Memotropil” - tablets;
- “Escotropil”, “Cerebrolysin”, “Cerebrolysate” - solutions for introducing medicine into the body by injection;
- "Cortexin" is a dry extract.
Substitutes are similar in composition to the drug "Cerakson". Before purchasing an analogue, you must agree with your doctor about a replacement.
The price for “Cerakson” in sachets varies from 1,270 to 1,490 rubles.
Injections, tablets "Ceraxon": what does the medicine help with?
Experts recommend the drug in the following cases:
- acute period of cerebral catastrophe - stroke;
- recovery period after already suffering brain damage;
- acute or already recovery period after TBI;
- various pathologies of brain structures of a vascular nature of development, in combination with various behavioral disorders and cognitive abilities in the patient.
Only a neurologist should recommend a nootropic drug - after assessing the individual severity of neurological symptoms, the patient’s age category, and his susceptibility to the treatment procedures being performed.
How to prepare a suspension from the contents of the sachet
In order to prepare the Ceraxon sachet suspension, you should separate one sachet from the other along the tear seam. Holding it vertically, carefully tear off the edge along the o. After opening, the contents of the sachet should be diluted in half a glass of water and drunk before meals or between meals.
Get examined and treated with Ceraxon by making an appointment with a neurologist at the Yusupov Hospital by phone. The contact center of the Yusupov Hospital is open 7 days a week, around the clock. Leading specialists in the field of neurologists individually select the optimal doses, course of treatment and pharmacological forms of drugs.
Contraindications
Based on the instructions for the drug "Ceraxon", it follows that the pharmacological drug has the following contraindications for use:
- a significant predominance of the tone of the parasympathetic department of the autonomic system;
- individual hyperreaction to the active and auxiliary components of the drug "Ceraxon", from which the medicine can cause side effects;
- children's category of patients, as well as adolescents under 17–18 years of age.
The drug is used with extreme caution if a person has a disorder of the liver and kidney structures. Under the mandatory supervision of a specialist, with monitoring of biochemical blood parameters.
As a rule, the pharmacological drug "Ceraxon", instructions for use and reviews indicate this, is well tolerated by patients. In rare cases, the following negative effects may occur:
- impaired sleep quality;
- intense pain impulses in the head;
- increased tremor of the limbs;
- hyperarousal;
- persistent dizziness;
- the appearance of various hallucinations;
- a pronounced feeling of numbness in paralyzed limbs;
- Dyspeptic disorders are possible - nausea, vomiting, or diarrhea:
- dermal rashes of an allergic nature, for example, urticaria;
- less often - anaphylactic shock.
After discontinuation of the drug, all of the above undesirable effects are completely eliminated.
Side effects
In rare cases, side effects occur when the drug is taken correctly.
These include:
- mental disorders that manifest themselves in the form of hallucinations;
- from the nervous system, headaches and dizziness are possible;
- dyspnea, from the respiratory system;
- decrease or increase in blood pressure;
- nausea and vomiting, less often diarrhea;
- allergic reactions may occur (urticaria, itching, burning, peeling of the skin); less commonly, Quincke's edema and anaphylactic shock may occur.
In rare cases, a side effect may manifest itself as a general deterioration in health with chills and swelling of the extremities.
The drug "Cerakson": instructions for use
How to give injections
The solution for injection drug delivery should be administered slowly, in direct proportion to the administered dose of the drug - but not less than 3-5 minutes. If the product is recommended for drip administration, then no more than 40–60 drops per minute. As a rule, the medicine is prescribed to patients mainly intravenously. In severe conditions, for example, a suddenly developed hemorrhagic stroke, the medicine should be administered at the earliest possible stage - to reduce the area of the pathological focus. From the instructions for the medication it follows that its use directly depends on the pathology that was diagnosed in the person:
Acute period of TBI, as well as ischemic stroke - 1000 mg of the drug "Ceraxon" every 10-12 hours, with a treatment course of at least 5.5-6 weeks. Then, based on individual needs, it is possible to switch to taking oral syrup or Ceraxon tablets.
The frequency of administration and the duration of the treatment course are also determined only by the doctor observing the patient. Changing them on your own is unacceptable.
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How to store Ceraxon
It is necessary to comply with the storage conditions of pharmacological drugs.
Optimal storage conditions include temperature, location, humidity, packaging.
Place. Keep the medicine in a dry, dark place, out of reach of children.
Temperature. Storage temperature of the drug:
- in the form of a solution for injection - +15... +30 °C.
- syrup - + 15... +30 °C;
- sachet - +15... +30 °C;
- tablets - +15... +30 °C.
Heating or freezing the substance is strictly prohibited.
Container/Packaging. The container with syrup must be tightly closed. It is recommended to store tablets and sachets in their packaging, without pouring or transferring them anywhere. The ampoules are kept unopened in a cardboard package.
Humidity. The storage location must be dry, with a relative humidity of no more than 60%.
Acceptability of sunlight. The package with the substance is kept away from sunlight. Exposure to sunlight has a detrimental effect on medications and can change their properties.
Optimal and destructive storage conditions
The best conditions for storing drugs: moderate temperature - +15... +25 ° C, dry place, without sunlight or light rays.
The worst place would be in the bathroom, near electrical appliances, in a place where sunlight penetrates.
It is not recommended to store tablets and sachets in the refrigerator. It is recommended to keep the solution, syrup and ampoules on the refrigerator door.
Analogue drugs
If an expired medicine is detected, it can be replaced with an active one in the same way:
- Recognan - solution;
- Vinpocetine - tablets;
- Tanakan - solution for internal use;
- Somaxon is a solution for injection.
When replacing, you should consult your doctor.
Safety of use
When taking the drug, you should consider its compatibility with others and alcohol.
It is prohibited to take the product with alcohol. It is possible to drink alcohol 15 days after the end of the course of treatment.
Ceraxon is not prescribed together with drugs that contain meclofenoxate. When taken with Levopoda, the drug enhances its pharmacological effect.
Overdose
No cases of overdose of Ceraxon have been identified.
The drug is dispensed from pharmacies with a doctor's prescription in Latin. The shelf life of the recipe is usually up to a year.
Drug interactions
Citicoline oral solution is fully compatible with dextrose and glucose solutions. During the treatment of patients with Alzheimer's disease who additionally take the drug Levodopa, the therapeutic properties of the latter drug may be enhanced.
This fact must be taken into account in the process of selecting the dosage of Citicoline, as well as prescribing the timing of the treatment course. The oral solution is contraindicated for simultaneous use with medications containing meclofenoxate, as the risk of side effects increases.
During therapy with Citicoline, it is necessary to avoid concurrent use of medications that are based on a similar active substance. Failure to comply with this rule can lead to an overdose, increased stimulation of the central nervous system and negative neurological symptoms.
Pharmacodynamics and pharmacokinetics
The pharmacodynamics of Citicoline is different in that this biologically active substance is a precursor of the basic ultrastructural elements of the cell membrane. These are mainly phospholipids, without which the full functioning of brain tissue is impossible.
Citicoline oral solution has a broad therapeutic effect, promoting the restoration of cells with damaged membranes. The active substance of this drug inhibits the properties of phospholipases and prevents the formation of free radicals. By influencing the physiological mechanisms of apoptosis, Citicoline prevents premature death of brain cells.
The pharmacodynamics of this drug is particularly pronounced in patients who have been diagnosed with pathological conditions of the central nervous system. In patients with acute stroke, the effect of reducing the area of damage to the cerebral cortex is achieved, and more active cholinergic transmission of neural impulses is stimulated.
Patients who have suffered a traumatic brain injury recover 2 times faster, the period of stay in a coma is reduced, and the symptoms of neurological disorders disappear. In patients with chronic hypoxia of the central nervous system, the drug Citicoline can improve memory functions, restore cognitive activity of the brain, and improve the patient’s quality of life.
The pharmacokinetics of Citicoline oral solution is characterized by rapid absorption of its constituent components, which are absorbed into the intestinal wall. The biological availability of this medication is the same as after its intravenous administration.
The metabolism of this nootropic drug occurs in the liver tissues, and also partially in the intestines. The chemical half-life products of the drug are the substances cytidine and choline. A high content of the latter component is found in the blood serum. Citicoline distributes evenly in brain tissue, activating its metabolite in the form of choline.
Having reached the brain tissue, Citicoline is integrated into the cellular structure of the cytoplasmic and mitochondrial membranes. Subsequently, the active substance of this drug is directly involved in the formation of phospholipids.
Clinical trials of Citicoline oral solution have shown that only 15% of this medication is excreted from the human body.
About 3% of the drug's half-life products are disposed of by the kidneys in urine. Another 12% is excreted along with carbon dioxide during the act of breathing. The rest of Citicoline's metabolites are used by the human body to maintain or restore brain function. The average duration of the complete elimination of chemical half-life products of the drug is 15 hours.
