Composition and dosage forms
The active substance of the drug is meglumine acridone acetate - acridone acetic acid. It is a stimulator of interferon production, which has an antimicrobial, anti-inflammatory effect and inhibits the development of tumors.
Cycloferon is produced in forms for oral, parenteral and local use:
- Coated tablets: brown or yellow, biconvex. The composition includes: 150 mg of active substance, methylcellulose and calcium stearate as auxiliary compounds. Packages contain 10 and 50 pcs.
- Injection. Transparent yellowish liquid in 2 ml ampoules. The content of meglumine acridone acetate is 250 mg per ampoule. Additional components: water and stabilizers.
- Liniment for topical use: a thick, gel-like yellow substance containing 5% active substance. Available in 5 ml tubes.
Use of Cycloferon in children and pregnant women
The instructions for the tablets suggest the use of the drug in children from four years of age in such doses;
- 4-6 years - 1 tablet per day;
- 6-11 years – 2 pieces per day;
- from 12 years old and adults – 3 tablets, respectively.
A second course of treatment should begin at least 2 weeks after the end of the previous one.
During pregnancy and breastfeeding, Cycloferon should not be taken with the exception of topical application of liniment.
Mechanism of action of Cycloferon
The drug corrects the body's immunity by activating the production of interferons. When administered orally, meglumine is concentrated in the tissues of the liver, spleen, lungs, and intestines, on which the production of lymphocytes depends. Cycloferon also accelerates the release of granulocytes in the bone marrow.
The medicine inhibits autoimmune processes, reducing the body's pathological reaction to rheumatoid arthritis and other systemic diseases, and reduces the body's negative reactions during chemotherapy. When applied topically, the ointment reduces inflammation and has an antiproliferative effect.
The highest concentration of Cycloferon in the body is observed 2.5–3 hours after administration. Over the next 4–5 hours, it decreases by half. Complete elimination of the drug takes 1–1.5 days. The active substance is not deposited in tissues, does not provoke mutation processes, and does not cause intoxication.
Cycloferon or Ergoferon - which is better and more effective for an adult
Manufacturer: MATERIA MEDICA, Russia
Release form: lozenges
Active ingredient: antibodies to interferon gamma
The analogue Ergoferon has a complex effect. The tablets have no taste, so there is no discomfort when taking them. The product is distinguished by its popularity and prevalence. In rare cases, side effects are observed during a course of taking the analogue.
Although Ergoferon is not so overpriced, it is better to use Cycloferon for the flu.
Indications
Cycloferon is used in patients from 4 years of age:
- in the treatment of herpetic infections;
- for neuroinfections;
- cytomegalovirus;
- intestinal inflammation of a viral nature;
- for the treatment of acute respiratory viral infections, acute respiratory infections;
- in the complex treatment of viral hepatitis, HIV.
Liniment is used in the treatment of urogenital infections. The solution is also indicated for chlamydia and connective tissue diseases.
Cycloferon or Ingavirin - which is better for adults and children
Manufacturer: VALENTA, Russia
Release form: capsules
Active ingredient: imidazolylethanamide pentanedioic acid
Ingavirin is a substitute and analogue of Cycloferon, recommended from 7 years of age. The drug has a significant list of contraindications that should be taken into account before starting treatment. The product is overpriced and has little effectiveness against influenza and ARVI. It differs in composition.
If you choose between Cycloferon and its analogue Ingavirin, then it is better to give preference to the first remedy. This is due to its cost and effectiveness. It is worth noting that none of the drugs presented will help with coronavirus.
Cycloferon for genital herpes
In addition to systemic therapy, applications with Cycloferon liniment are used:
- a thin layer of the product is applied to the affected areas daily for 5–7 days;
- use the drug for intravaginal or transurethral instillation, injecting 5 ml daily for 2 weeks;
- cotton swabs soaked in ointment are inserted into the vagina for 10–15 days.
Cycloferon ointment can be alternated with the use of other topical drugs.
Cycloferon in the form of a solution
To prevent a number of diseases, this drug can be administered intramuscularly or intravenously . Most often this is done if a person has had contact with a sick person. The product can be administered once. If infection has already been detected, the dosage is determined by a specialist depending on the characteristics of the patient and the form of the disease.
For influenza, Cycloferon is often administered intramuscularly once every 2 days for 10 days. And with a herpetic infection it’s the same. The daily dosage is 250 mg. Cycloferon in the form of a solution can be a component of complex therapy for acute viral hepatitis , the course of therapy lasts in this case 2 weeks, and the daily dose is 500 mg.
Contraindications
It is necessary to refuse treatment with the drug:
- with uncompensated cirrhosis;
- severe liver failure;
- individual intolerance to components;
- development of an allergy to the drug.
The medicine is also prohibited for the treatment of children under 4 years of age.
Those suffering from diseases of the gastrointestinal tract need to monitor their well-being when using tablets. In case of disturbances in the functioning of the endocrine system, treatment requires special care and medical supervision.
Analogues of the drug
In terms of effects on the human body, drugs such as:
- Arbidol;
- Esberitox;
- Galavit;
- Alocain-Alpha;
- Pyrogenal;
- Lavomax;
- Septilin;
- Etzinacin and others.
Some experts often tell patients that Cycloferon is the best way to protect the body from colds in winter and that only vaccination is more effective. However, you should not prescribe the drug yourself; it is better to consult with a specialist , and do not forget to strictly follow the instructions in the instructions so that side effects do not occur.
Cycloferon or Kagocel - which is better and more effective for adults and children
Manufacturer: NEARMEDIC PHARMA, Russia
Release form: tablets
Active ingredient: kagocel
Kagocel is an analogue of Cycloferon for children. It is an antiviral drug with the active substance of the same name. Allowed for children over three years of age.
The Kagocel analog has the same indications and is effective for these pathologies. Reviews about these products are positive, as they are effective.
Cycloferon or Anaferon – which is better?
Manufacturer: MATERIA MEDICA, Russia
Release form: drops, lozenges
Active ingredient: antibodies to interferon gamma
Anaferon is a domestic analogue of Cycloferon, which is distinguished by its low cost. Age restrictions regarding admission depend on the form of release. The drug has a minimal list of contraindications, which is an inherent advantage. Refers to antiviral agents that activate the immune system. Has antimutagenic properties.
Anaferon is prescribed for the treatment of the following pathologies and disorders:
- ARVI, influenza;
- Infectious mononucleosis;
- chickenpox;
- labial and genital herpes;
- chronic herpesvirus infection;
- tick-borne encephalitis;
- enterovirus;
- rotovirus;
- coronavirus;
- calicivirus;
- viral and bacterial infections.
The drug is allowed to be used as a complex therapy for secondary immunodeficiency disorders of various etiologies.
Reviews about Cycloferon
Patients who have experienced the effect of this drug note that they began to feel better within 2-3 days after starting treatment. The original Cycloferon and Russian-made analogues are able to protect the body during the height of epidemics. 90% of patients were successfully treated for herpes and facial rashes. With strict adherence to medical indications, those being treated improve their well-being and reduce the number of exacerbations of chronic diseases.
There are also a lot of negative reviews. Most dissatisfied patients complain of insomnia, headaches, and allergic reactions while taking the drug. As a rule, such complaints arise due to improper use of the medication or the discovery of individual intolerance to one of its components.
Cycloferon or Rimantadine – which is better and more effective?
Manufacturer: Biosintez, Russia
Release form: syrup, tablets
Active ingredient: rimantadine
Rimantadine is an inexpensive analogue of Cycloferon. Age restrictions regarding use depend on the form of release of the drug. Prescribed to patients as treatment and prevention of influenza in adults and children from seven years of age. The drug is used for tick-borne encephalitis of viral etiology.
The analogue Rimantadine is rapidly absorbed from the gastrointestinal tract. The pharmacological effect of administration is observed during the first day. Patients diagnosed with kidney problems should be excluded from therapy. The product has a minimal list of contraindications and side effects.
For influenza and ARVI, both drugs will be equally effective. Therefore, when choosing one or another antiviral agent, you need to take into account the composition, restrictions, age and cost.
Cycloferon or Cytovir 3 – which is better?
Manufacturer: CITOMED, Russia
Release form: tablets, capsules, syrup
Active ingredient: sodium alpha-glutamyl-tryptophan
Cytovir 3 is a domestically produced analogue of Cycloferon. Prescribed for adults and children from six years of age. It is distinguished by its effectiveness against influenza and ARVI. It has a small list of contraindications that must be taken into account before starting a course of treatment.
Instructions for use
Cycloferon injections are given intramuscularly and intravenously (if necessary). The injection is performed once every 24 hours for the first two days, then once every 48 hours (on days 4, 6 and 8), then 1 injection every three days (11, 14, 17, 20, 23). This is the basic regimen used, the course depends on the type of pathology and the duration of the selected therapy. The dosage and features of taking this drug depend on the age category of the patient.
Cycloferon solution for adults:
- Pathologies of joints of a dystrophic-degenerative nature. 5 injections at a dose of 0.25 g, break 14 days, and repeat the regimen.
- Neuroinfections. Treatment according to the basic regimen (12 injections).
- Chlamydia. Therapy in the form of a basic regimen + antibiotics.
- Hepatitis. A single dose is 0.25–0.5 g, treatment duration is 10 injections, a break of 2 weeks and again 10 injections.
- HIV AIDS. The standard regimen is 10 injections of 0.5 g, then 1 injection every 5 days for 2.5 months. The course is repeated after 30 days.
- Herpes, cytomegalovirus. 10 injections of 0.25 g according to the scheme, the maximum effect is achieved during therapy in the acute stage.
- Rheumatism, other systemic diseases. 5 injections of 0.25 g according to the scheme. Repeat the course 4 times with breaks of 2 weeks.
