Gepatrombin G


Release form

Gepatrombin G ointment is available in aluminum tubes with a capacity of 20 mg. The kit includes an elongated plastic cap designed to simplify the application of the drug inside the affected area (rectum).

The drug itself is a translucent whitish gel with a possible yellowish tint. The consistency of the ointment is light, easily distributed when applied. There is a specific smell.

It is up to the consumer to decide which is better: suppositories or ointment. But, it should be mentioned that suppositories are only suitable for rectal administration and they do not treat the external area. Whereas the ointment is intended for comprehensive treatment of this disease.

Hepatrombin suppositories are widely popular, the therapeutic composition of which is exactly the same as that of the ointment. But, you should keep in mind that suppositories are only suitable for internal (rectal) use. But complex treatment of hemorrhoids should also include external use (at least prophylactically). The gel has universal use due to its easily absorbed texture and a special elongated cap that makes administration of the drug as convenient as possible.

There are three forms of release of the drug. Some are concerned about the question of which is better: Gepatrombin Gel or ointment? The difference lies in the method of application of these forms of the drug and the duration of their effect on the tissue.

The gel is instantly absorbed, “delivering” the active substances to the tissues as quickly as possible. This is convenient, especially for active people.

Ointments have a thick texture. to “give” for a long time after application.

medicine to tissues. The downside is that such a place will need protection from smudging. The ointment will rub off on your clothes. For external use, it is necessary to apply a protective bandage. For internal (rectal) use, ointment is preferable.

Compound

The composition of hepatrombin ointment was very well chosen.

For 1 gram of the drug there are:

  • heparin sodium - 65 IU. A substance that effectively prevents the formation of blood clots. Obtained from the tissues of the small intestine or lungs of cattle or pigs. Promotes regeneration (restoration) of mucous membranes and connective tissue;
  • lauromacrogol 400 - 30 mg. Causes sclerosis (gradual thinning of the walls of blood vessels, their gluing) of the affected veins. Anesthetizes (numbs) the hemorrhoid area;
  • prednisolone acetate - 2.233 mg. Reduces blood circulation in affected vessels. Relieves allergic reactions, burning, itching, pain.
  • The ointment also includes various auxiliary and ballast substances , which do not have a special role in the formation of the therapeutic effect.

pharmachologic effect

Hepatrombin is a combined drug for external use that has antithrombotic, regenerative, anticoagulant (inhibits blood clotting), anti-edematous and anti-inflammatory properties.

Hepatrombin contains sodium heparin, dexapanthenol and allantoin.

Heparin is a direct anticoagulant, which is explained by its inhibitory effect directly on coagulation factors. This substance is extracted from the lungs of cattle. Heparin inhibits reactions that cause blood coagulation and the formation of blood clots, improves blood supply, and helps flush out stagnant tissue fluid and harmful products formed as a result of metabolism.

The other two components of Hepatrombin enhance the effect of heparin, improve its penetration, and also protect the skin.

Hepatrombin G is an antihemorrhoidal agent.

This drug contains heparin, prednisolone acetate and polidocanol.

Heparin causes the antithrombotic, anti-inflammatory and antiexudative (removes fluid formed at the site of inflammation) effect of Hepatrombin G.

Heparin prevents blood coagulation in hemorrhoids and participates in the regeneration of connective tissue. Prednisolone contained in Hepatrombin G enhances the effect of heparin and also reduces the inflammatory process, pain, burning and itching in the anorectal area. Thanks to polidoknol, Gepatrombin G promotes sclerosis of hemorrhoids (gluing the walls of the node with its subsequent drying) and has a local anesthetic effect.

Analogues and cost

The financial situation of people can be different, and anyone can have problems with hemorrhoids. In addition, not every pharmacy can provide a full range of medicinal products for the treatment of this disease. A suffering person is faced with the acute question of how to choose hepatrombin ointment analogues.

The main active substance of the drug is sodium heparin, on the basis of which various manufacturers produce fairly high-quality ointments for hemorrhoids.

Heparin ointment

Ingredients: sodium heparin 100 IU (reduces inflammation and prevents thrombus formation), benzocaine 40 mg (dilates blood vessels, promotes better absorption of the drug), benzyl nicotinate 800 mcg (reduces pain). Heparin ointment is an ointment for external use. The product is applied to a gauze pad and applied to the affected area . But when treating hemorrhoids, it is also possible to insert a tampon with an applied substance into the anus.

There are differences between hepatrombin and heparin ointment, moreover, of a qualitative nature:

  • The absorption of the active substance is very different between these products. Hepatrombin is easily distributed and quickly absorbed;
  • Gepatrombin does not require additional means for application; it is enough to simply apply it to the diseased surface or inject it internally;
  • The price issue, of course, leaves hepatrombin ointment far behind heparin ointment. The cost of one package of heparin ointment (depending on the manufacturer and price markups in pharmacies) of the same volume as Gepatrombin G varies from 46 to 75 rubles .

Heparoid Ointment Zentiva

Composition: heparinoids 100 units.

Czech product. It is produced in the form of not exactly an ointment, but rather an oily emulsion. Absorption is high. The cost of packaging is 30 g. Is about 150 rubles .

Proctosan Neo

Available in the form of suppositories and gel. Contain exactly the same active substances. Tube with applicator on cap. Produced by the Serbian pharmaceutical company Hemofarm AD. The cost is about 140 rubles. The most accurate analogue of Gepatrombin G mazin on the modern market.

Proctosedyl ointment

An ointment that duplicates heparin in composition. Produced by a joint venture between India and Ukraine. Cost 56 rubles per tube of 10 g.

The cost of the drug Gepatrombin G for a standard 20 g tube is from 200 to 260 rubles , depending on the region. Additional “cheats”

in pharmacies.

Gepatrombin 50000 ointment contains:

  • Heparin sodium 50,000 IU;
  • Allantoin 300 mg. Stimulation of cellular and tissue metabolism. Acceleration of regeneration processes (restoration through the growth of identical tissue) of damaged cells;
  • Dexpanthenol 400 mg. Enhances tissue absorption of heparin, stops the development of ulcers and wounds, and actively promotes their healing.

Analogs

A structural analogue of Gepatrombin in terms of the active ingredient is the drug Hepalpan.

Drugs with a similar mechanism of action and belonging to the same pharmacological group are: Agiolax, Aescin, Avenok, Aurobin, Gepatrombin G, Laxigal, Vasoket, Venocomfort, Papaverine, Ginkor Procto, Olestezin, Fiberlex, Prostopin, Detralex, Hypozol, Butadione, Venoruton, Bisacodyl , Tykveol, Rutin, Aethoxysclerol, Sulgan, Pramoxin, Dulcolax, Laxatin, Diovenor 600, Piolysin, Proctosedyl, Posterisan, Picosulfate, Relief Ultra, Romphalak, Simetride, Phlebodia 600, Aesculus, Procto Glivenol, Venarus, Stress formula with iron, Antihemorrhoidal collection , Nefluan, Mucofalk, Metovit, Natalsid, Metrogyl, Heferol.

Indications for use of the drug

Correct use of Gepatrombin G ointment stops inflammatory processes in tissues and promotes “self-destruction”

affected veins, prevents the formation of blood clots, and also “dissolves” existing ones.

Conditions that require the use of Gepatrombin G:

Acute or chronic hemorrhoids

Chronic hemorrhoids are a progressive disease. It will not disappear on its own, even if you change your occupation. It manifests itself in the presence of blood impurities in the stool, the formation of round, soft to the touch, protrusions. The size of these protrusions varies from 0.5 centimeters to two. They are formed by swollen veins and filled with blood. When solid feces pass, mechanical trauma to these areas occurs and, as a consequence of this damage, bleeding occurs. Constant loss of blood threatens a person with anemia and anemia. A person may not feel pronounced pain in the anus. But the discomfort that signs of chronic hemorrhoids cause should pay close attention . Treatment should be started immediately, before the disease develops into an acute form.

Acute hemorrhoids cannot be ignored. The symptoms of this painful condition are pronounced. It is impossible to confuse it with anything else.

Inflammation of tissues, thrombosis of blood vessels and prolapse of hemorrhoids lead to extreme discomfort and acute intolerable pain. Bleeding occurs not only during the act of defecation. In the most advanced cases, gradual necrosis (death) of hemorrhoidal tissue occurs. Inflammation can spread to neighboring tissues. Due to swelling in the passage, constipation worsens, which only increases the load on the sore area.

Hemorrhoids without symptoms

"Insidious"

type of disease.
Hemorrhoidal changes are already present, but the patient is not yet aware of their existence .
In everyday life, people do not tend to pay much attention to their health, especially to such an intimate place as the anus. But if they had undergone a special examination, the result would have more than surprised and alarmed them. More than half of pregnant women, people involved in heavy, strength sports, and workers who spend most of their working time in a sitting position would show signs of hemorrhoids.

A timely preventative course with special drugs could completely save a person from the impending threat.

“It is almost impossible to identify signs of an emerging disease visually and by palpation. A special diagnostic procedure is required - sigmoidoscopy. Unfortunately, doctors do not perform it without special symptoms (only for a fee). This is the main “catch” of early diagnosis of hemorrhoids.”

Phlebeurysm

Vessels “clogged” with blood clots and chronically compressed become overfilled with blood. Their walls lose tone and swell.

Itching in the anus

The inflammatory process provokes itching in the anus. Swollen hemorrhoids “attract attention”

in such a specific way.
Hepatrombin G has an anesthetic effect and helps relieve discomfort, itching and pain .

Anal fissures and bleeding

Hemorrhoids and constipation provoke the appearance of anal fissures. A soft tissue crack looks like a gap, bleeds, and causes severe pain. In addition, there is a danger of introducing infections into the body and blood poisoning.

It is formed as a result of damage during the exit of solid feces through the anus affected by hemorrhoidal changes. Cracks are also scary because they cause endless pain for a person suffering from hemorrhoids. Difficult bowel movements are “disturbing”

cracked living tissue, which causes severe pain.
The pain causes a reflex spasm of the anal sphincter, which makes defecation almost impossible. A “vicious circle”
closes .

Prolapse of the hemorrhoid, its pinching

An advanced disease entails the loss of hemorrhoidal “bumps”

out. Loss occurs even with minor physical exertion. Putting them back is quite difficult or impossible at all. Then they remain outside the anus. It's uncomfortable when walking. For this reason, it is simply impossible for the patient to sit down.

Infringement of hemorrhoids occurs when the fallen “bumps”

impossible to straighten. Blood vessels in the nodes are stopped by blood clots. The condition is extremely serious, threatening tissue necrosis;

Use for other diseases

Gepatrombin ointment may have indications for use other than hemorrhoids.

A drug that prevents the formation of blood clots in blood vessels, with a strong anti-inflammatory effect, can be used in the treatment of many diseases.

Gepatrombin ointment for varicose veins

Method of use: three times a day, Hepatropin G ointment is applied to the legs with massage movements in the direction from bottom to top. It is recommended to wear special compression garments or an elastic bandage.

Multiple cases of use of this drug have confirmed its high effectiveness in the treatment of varicose veins with hepatrombin ointment for legs . "Dissolving"

thrombotic formations in the veins. Swollen, clogged veins, which no longer effectively perform their important functions, undergo sclerosis. This reduces the external, disfiguring symptoms of varicose veins. The condition of veins located close to the surface of the skin improves significantly.

Gepatrombin ointment for bruises

The product has a powerful thrombosis-absorbing effect . Hematomas are just such a physiological phenomenon. Broken small blood vessels lose blood, which then clots. A local thrombotic formation is formed. The blood cells responsible for the gradual destruction of such pathological foci require a long amount of time to complete their work. Heparin, which is part of the ointment, quickly copes with hematomas, speeding up the healing process by half .

Application and dosage

Gepatrombin G ointment for hemorrhoids is applied over the entire surface that needs treatment . It is necessary to lubricate the external lesions and, immersing the applicator in the anus, inject the drug into the rectum.

External use: the area affected by hemorrhoids must be thoroughly washed and dried. A strip of gel 4 centimeters long is squeezed out. The ointment is applied in a thick layer. The affected surface is covered with the product without rubbing. Insertion into the rectum is made using a special cap. If possible, it is advisable to carefully spread the injected ointment inside the body. Before rectal administration of the drug, it is necessary to have a bowel movement or an enema.

The drug is used, depending on the severity of the disease, from two to four times a day.

Treatment of chronic hemorrhoids

After the signs of existing hemorrhoids have passed, it is necessary to continue using the ointment for another week. This will consolidate the result obtained and act as a prevention against relapse.

Contraindications

Before using Gepatrombin ointment or gel, the instructions should be carefully studied, since in some cases this drug is contraindicated:

  • hypersensitivity to the active ingredients of the drug;
  • violation of skin integrity (when using gel);
  • infected skin lesions;
  • thrombocytopenia (decreased platelet concentration in the blood);
  • increased bleeding (hemorrhagic diathesis);
  • hemophilia (hereditary disease characterized by increased bleeding).

The use of Gepatrombin by pregnant and lactating women is possible only under strict indications after consulting a doctor.

Gepatrombin G ointment and suppositories cannot be used for:

  • hypersensitivity;
  • viral, bacterial or fungal skin lesions;
  • tuberculosis;
  • syphilis;
  • skin tumors;
  • predisposition to bleeding;
  • reactions to vaccine administration;
  • pregnancy (first trimester).

During pregnancy

Gepatrombin G ointment has proven itself to be excellent during pregnancy. Women in an interesting position often have problems associated with the inability of some organs and tissues to withstand increased stress. An enlarged and heavier uterus puts especially merciless pressure on the organs located below it in location. Venous and arterial blood flow is disrupted to such an extent that blood clots can occur inside the vessels. Congestion in the pelvic area aggravates the situation.

Self-medication with such a potent drug during pregnancy is strictly prohibited. You should not listen to the advice of “experienced” girlfriends and advertising on the Internet and on television. For Gepatrombin ointment, the instructions for use clearly state a ban on use in the first three months of pregnancy. But this does not mean at all that during the remaining periods the ointment can be used uncontrollably. The drug is used strictly only with the permission of a doctor and under his supervision! Ingredients

Dosage: apply the ointment to a clean body twice a day. The duration of use and the use of additional treatments is determined only by a doctor. It is he who will determine the detailed instructions that should be followed during treatment.

It should be remembered that the use of this drug, like many others, is contraindicated in the first trimester of pregnancy . During this period, the formation of all vital organs and systems occurs. The use of such a potent and effective drug should be postponed until a less dangerous period of pregnancy.

special instructions

During pregnancy and breastfeeding, the use of Gepatrombin is not recommended, except in cases where the potential benefit to the mother outweighs the possible risks to the fetus or child. For example, it is allowed to use Gepatrombin ointment for mastitis, which mainly develops during lactation. However, it is necessary to purchase a drug that contains no more than 300 IU of heparin per 1 g.

Data on Gepatrombin overdose and its drug interactions are not provided.

The use of Gepatrombin does not affect the ability to control potentially dangerous mechanisms that require increased concentration.

Reviews

Elena Mikhailovna, 38 years old
I have been suffering from chronic hemorrhoids for a long time. Numerous folk remedies provided relief from this problem for a short period. I’m used to putting up with discomfort in the intimate area. I tried hepatrombin ointment. At first the effect was only anesthetic. I thought that this would be the end of the effectiveness of the drug. But no. Gradually I began to notice that I was paying less and less attention to pain and itching. The bumps stopped falling out of the anus. I used this wonderful product for 2 months. I feel like a healthy person!

Fedor Andreevich, 50 years old I work as a driver. I have to work while sitting. I have felt the presence of a problem for a long time. I was ashamed to go to doctors. He constantly postponed the visit, even when it was very painful. Then it happened that it was simply impossible to sit down, so I couldn’t go to work. Something had to be done urgently! I'm not pregnant and generally healthy. Therefore, at my own peril and risk, I decided to use Hepatrombin on my own. I felt better after 2 weeks. I continued the course just in case. Now I feel healthy.

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