Yox throat spray with iodine - instructions for use for adults and children

Compound

100 ml of topical solution contains 8.5 g of povidone-iodine and 0.1 g of allantoin . The following excipients were used: citric acid monohydrate (0.1 g), levomenthol (0.5 g), sodium citrate dihydrate (0.1 g), as well as 10 g of 96% ethanol, 15 g of propylene glycol and 50 g of purified water.
30 ml of spray contains 2.55 g of povidone-iodine and 0.03 g of allantoin . Components such as citric acid monohydrate, levomenthol, sodium citrate dihydrate, 96% ethanol, propylene glycol and purified water were also used as excipients.

Spray composition

The spray is based on a povidone-iodine complex.

The substance povidone is a sorbent, due to which active iodine is gradually released.

The content of povidone-iodine is 2.55 grams. The iodine concentration in the complex is no more than 1%.

The second active component of the drug is allantoin (contains 0.03 grams). It has anti-inflammatory, antiseptic and regeneration-stimulating effects.

Additional substances in Yox spray:

• Levomenthol;
• Ethanol (about 25% volume);
• Citric acid, its sodium salt;
• Binding component;
• Water.

The spray has the smell of alcohol and menthol, a characteristic brown color, and the taste of iodine.

Yox spray is available in glass and plastic bottles of 30 milliliters.

Yox is not an aerosol: the product does not contain a propellant. Spraying is done by pressing a mechanical sprayer.

Release form

A red-brown solution (volume 50/100 ml) is available in bottles made of dark glass with propylene caps, one in a cardboard box. To protect the integrity of the packaging, a tamper-evident control is provided, and a measuring cap is provided for ease of use.

The spray (volume - 30 ml) is available in bottles made of polyethylene terephthalate; they are equipped with mechanical sprayers and have lids to protect the sprayer. The drug is packaged in a cardboard box and equipped with an applicator with a rotary lever.

Which is better - Yox or Lugol?

Two fundamental differences should be highlighted:

• Lugol - aqueous solution with glycerol;
• Yox is an aqueous-alcoholic solution of the povidone-iodine complex.

These differences allow us to make the following comments about the benefits of these drugs.

Benefits of Yox:

• The presence of iodine in combination with povidone promotes a longer antimicrobial effect;
• Alcohol solutions are considered more effective antiseptics than water solutions.

Lugol's advantages:

• The absence of alcohol in the composition makes the spray more appropriate for use in children;
• The substance glycerol makes the product viscous, the liquid envelops and remains on the mucous membrane for a long time.

In addition, Lugol has a more affordable price.

However, consumers who have used both drugs prefer Yox.

Pharmacodynamics and pharmacokinetics

Povidone-Iodine is a disinfectant that is a complex of iodine with polyvidone, a high-molecular compound that can reduce the toxic effects of iodine on the body's cells. It is characterized by a wide spectrum of antimicrobial action due to a direct effect on the proteins of microorganisms ( proteolytic properties ). It has a partially bactericidal effect on gram-positive and gram-negative cocci and bacilli , as well as on individual anaerobic bacteria, yeast , and also on protozoan viruses .

Allantoin can have an anti-inflammatory effect, which in combination with polyvidone gives a therapeutic effect.

The drug easily penetrates the epithelial of the respiratory tract mucosa and gives a quick effect in acute and chronic diseases.

Iodine in the body is converted into iodides, which are mainly accumulated in the thyroid gland. They are excreted primarily by the kidneys and in small quantities through feces, sweating and salivation.

Analogs of Yox spray

The medicine does not have exact analogues containing povidone-iodine and allantoin.

There are 2 iodine-based medicines available in pharmacies (release form - solution and spray), which can be used for respiratory diseases:

Iodinol

Lugol

Lugol exists in Lithuanian and Russian versions. Iodinol is a Russian-made drug. The active ingredient in both cases is iodine.

In Lugol, the substance is mixed with glycerol, which gives the drug an enveloping effect. Iodinol is a water-alcohol solution of iodine.

Indications for use

• infectious and inflammatory processes in the oral cavity and pharynx, including tonsillitis , tonsillitis , tonsillopharyngitis , glossitis and aphthous stomatitis ;
• treatment of the oral cavity and pharynx during surgery on the airways and oral cavity, as well as in the postoperative period;
• first symptoms of flu ;
• treatment of various infections of the mouth and throat resulting from chemotherapy ;
• streptococcal tonsillitis (in combination with antibiotics ).

Spray Yox

Yox spray is available in 30 (45) ml bottles, which contain active substances: povidone-iodine 2.550 g, allantoin 0.030 g. This is a transparent or translucent reddish-brown liquid, highly soluble in water.
The package contains a special convenient applicator for irrigating the throat cavity. The spray is used for infectious inflammatory diseases of the oral cavity and pharynx (including tonsillitis, tonsillitis, tonsillopharyngitis, glossitis, stomatitis, aphthae). It is used to treat mucous membranes before and after surgical operations on the respiratory tract and oral cavity. Effective against influenza. In combination with antibiotics, Yox spray is used to treat complex sore throat (streptococcal). I would like to note that many people characterize the effect of Yox spray as immediate. Even with a strong cough or sore throat, relief from these symptoms begins immediately after irrigation of the mucous membranes. Some Internet users note in their messages that if you start using the drug as soon as the first signs of a sore throat appear, additional treatment with antibiotics can be avoided.

Treatment methods, dosage and contraindications

Yox throat spray (aerosol) should be used to irrigate the inflamed and infected mouth and throat 2 to 4 times a day. In particularly difficult cases, this procedure should be repeated every 4 hours. To do this, you need to remove the protective cap, put on the applicator, make 2-3 control presses to fill the applicator with the solution.

Useful information: Miramistin (spray, solution, ointment): instructions, features of use for the throat in children, men, women, in gynecology, pregnancy and other areas

Next, insert the applicator into the oral cavity, close your mouth, hold your breath and make 2-3 presses on the right and left sides of the throat. After use, the applicator should be rinsed thoroughly under running hot water.

As with all other forms of the drug Yox, contraindications are children under 8 years of age, pregnancy, lactation, thyroid disease, heart failure, kidney disease, and the use of radioactive iodine.

Side effects, time of use and overdose

Yox can cause an allergic reaction due to hypersensitivity to any of the constituent components. Itching, urticaria, dry mucous membranes and a burning sensation in the area of ​​application may occur. With prolonged use, signs of excess iodine may be observed: a metallic taste in the mouth, swelling of the eyelids and larynx, increased salivation.

If any of the above or other signs of an abnormal condition of the body appear, you should stop using the drug and consult a doctor for rehabilitation therapy.

The use of Yox as an external medicine is possible for a long time. But if there is no improvement from taking the drug within three days, it should be replaced with another more effective one.

There is no overdose if the drug is used correctly. Since Yox spray (aerosol) is applied topically, an overdose can really be excluded. If the patient swallows or inhales the drug, which is extremely unacceptable, of course, some signs of poisoning may appear (described above).

Interaction with other drugs

The use of Yox spray with other antiseptic and anti-inflammatory agents for external use is undesirable. Especially if they contain hydrogen peroxide or other antimicrobial substances.

Contraindications

• dysfunction of the thyroid gland, for example hyperthyroidism ;
• decompensated heart failure ;
• renal failure;
• dermatitis (herpetiform lesions);
• simultaneous use of radioactive iodine , the interval before treatment with Yox is at least 2 weeks;
• age up to 6 years;
• pregnancy or lactation ( breastfeeding );
• hypersensitivity to the components of the drug Yox.

What contraindications does Yox have?

Each medicine has contraindications, ranging from hypersensitivity to the drug and ending with certain diseases. Indications for refusing to use Yox are thyroid disorders, heart failure, radioactive iodine intake, dermatitis herpetiformis, allergy to any of the components of the drug. Yox should not be used as a medicine by children under 6 (8) years of age.

When rinsing or irrigating the mouth, it is not advisable to swallow Yox. This is a drug for external use. It should be explained why Yox is undesirable for thyroid diseases. Once in the patient’s body, iodine is released from the drug and, after performing its functions, can be excreted through the affected mucous membranes, with feces, saliva and sweat. And it can break down into iodides and accumulate in the thyroid gland, which negatively affects the functioning of this gland, especially if problems with it already exist.

>>We recommend: if you are interested in effective methods of getting rid of chronic runny nose, pharyngitis, tonsillitis, bronchitis and persistent colds, then be sure to check out this page of the site after reading this article. The information is based on the author’s personal experience and has helped many people, we hope it will help you too. Now let's return to the article.<<

Can it be used during pregnancy and lactation?

Another group for which Yox is contraindicated are pregnant and lactating women. This is mainly due to the high toxicity of iodine. The body of a pregnant woman may react too strongly even to a microdose of this substance that is acceptable for others. As a result, headaches, coughs, runny noses, problems with the lungs, eyes, and heart appear.

A similar picture can happen to a small child during breastfeeding by a mother using Yox to treat a cold. These negative aspects can appear because iodine in the form of iodides perfectly penetrates through the placenta and mammary ducts into the baby’s body.

Side effects

Allergic reactions are possible if hypersensitivity to any of the components of the drug Yox is established, which manifest themselves in the form of itching , urticaria , dry mouth and hyperemia angioedema occurs extremely rarely . In case of these reactions, discontinuation of the drug is recommended.

Long-term use can lead to the phenomenon of iodism and the appearance of a metallic taste, increased salivation, swelling of the eyelids and larynx.

Yox and children: a few nuances you need to know

There is no special form of Yox for children; there is an option to use Yox solution for the treatment of diseases of the ENT organs in children, starting from the age of 6, and a spray from the age of 8. It should be taken into account that not every child knows how to hold his breath while spraying and control swallowing movements while rinsing. If the parents are confident that the child will cope, then treatment with the drug can begin. The spray for children, as for adults, is effective against many pathogens, viruses, bacteria, and fungi.

At the St. Petersburg Research Institute, studies were conducted to determine the effectiveness of Yox for childhood diseases of the upper respiratory tract. In the case of sore throat, pharyngitis, tonsillitis and throat inflammation due to ARVI, Yox spray for children was used 2 times a day.

The maximum number of days of treatment was a week. Some children noted a cessation of itching after 1 application. The condition was formalized and within 3 days all symptoms disappeared. Only 2% of children experienced a burning sensation in the area of ​​spray irrigation, which indicates hypersensitivity and possible allergies. The test data became a “guide to action” for many parents whose children get sick especially often. Yox is an effective antiseptic of synthetic origin, used without fear in pediatric patients from 6 (8) years of age.

Instructions for use of Yox (Method and dosage)

Both the solution and the spray are used topically. It is recommended to dilute the solution with water in a ratio of 1 to 20–1 to 40, that is, 2.5 ml or 5 ml (measured with the measuring cap included in the package of the drug), or 0.5–1 teaspoon. spoons in 100 ml of water. The resulting solution should be rinsed in the mouth and pharynx 2–4 times a day; if necessary, more frequent use is permissible - up to 6 times a day with a minimum interval between rinses of 4 hours.

Instructions for using Yox spray boil down to the following algorithm:

• rinse the applicator with hot water;
• remove the cap, install the applicator, press the applicator several times so that the solution enters the sprayer and can spray after subsequent presses;
• then place the applicator tube into the oral cavity approximately 2–3 cm deep;
• holding your breath, press the irrigation cap twice, the first time on the right side, the second time on the left side of the mouth.

The spray is usually used 2-4 times a day. For more frequent use, the interval should be at least 4 hours.

The duration of treatment should be determined by the attending physician depending on the nature of the disease.

How to use the product?

Yox spray is not recommended for use with other antiseptics. Before use, gargle with warm water.

Spray application:

1. If the bottle with Yox has a removable applicator, you should remove it from the packaging and then put it on the sprayer, having previously removed the protective cap.
2. Press several times until the iodine preparation begins to spray.
3. Caution should be exercised: if the drug gets on clothing, it leaves permanent marks.
4. When using, you need to hold the bottle only vertically.
5. Insert the applicator tube shallowly into your mouth and point it to the left.
6. Hold your breath.
7. Press the spray applicator once.
8. Point the spray wand to the right.
9. Click once.
10. Remove the applicator after completing the procedure and rinse with warm water.
11. If a non-removable spray device is installed on the Yox bottle, steps 2-9 should be followed.

The spray can be sprayed as needed 2-5 times a day.

Instructions for children

It is not recommended to use Yox for children under 8 years of age.

Such measures are based on objective grounds:

• The drug contains alcohol;
• When spraying, you need to hold your breath;
• Yox spray has an increased ability to irritate the mucous membrane of the throat.

However, the product has a significant advantage that makes it preferable to other antiseptics: Yox spray does not contain antibiotics or synthetic antimicrobials.

Iodine is a natural antiseptic and, in addition, takes part in metabolic processes.

Thus, there is no harm from Yox - provided that the child does not have an overactive thyroid gland.

Pregnancy and lactation

According to the instructions for use, Yox cannot be used during pregnancy and lactation. There have been no studies on the effect of the drug on children, but two components - alcohol and iodine - are absorbed from the mucous membrane.

The amounts of these substances in a spray dose are microscopic. However, the same iodine, for example, is a highly active substance, the daily requirement of which, even in pregnant women, does not exceed 0.2 milligrams. A whole bottle contains about 14 milligrams of iodine.

Despite the ban on the use of the product, doctors prescribe it during pregnancy:

1) Firstly, the substance iodine is deposited in the body: about 10 milligrams are stored in the thyroid gland, another about 5-7 milligrams are stored in other organs. The absorption of the substance from the drug is insignificant: such an amount cannot affect the balance of iodine in the body. Oversaturation of the body with iodine occurs as a result of prolonged and systematic use of drugs or foods rich in iodine.

In this case, oversaturation expresses itself with obvious signs:

• The appearance of a metallic taste,
• Edema,
• Increased salivation
• Allergic manifestations.

The use of Yox cannot lead to an overdose .

2) Iodine is still necessary for a pregnant woman. In areas where consumption of seafood rich in this element is low, iodine intake is required for the health of the unborn child and pregnant woman.

3) Thirdly, Yox spray based on iodine is an extremely effective drug.

Taken together, the above factors indicate that the benefits of using the drug outweigh the possible negative consequences.

The restriction on use for lactating women is explained by the fact that the mammary gland is also involved in storing iodine. Thus, nature provided for the substance to be supplied to the child through mother’s milk.

Interaction

It is not advisable to use with antiseptics containing hydrogen peroxide , since there is a high probability of inactivation of the active substances.

Concomitant use with lithium causes an additional hypothyroid effect .

It is not advisable to use with chlorheximide , silver sulfadiazine , alkaloid salts and mercury .

Iodine is not compatible with:

• iron salts;
• bismuth;
• copper;
• lead;
• potassium chlorate and other oxidizing agents;
• mineral acids;
• strychnine hydrochloride ;
• quinine sulfate and other alkaloid salts.

special instructions

The drug should not be taken orally, including inhaled or swallowed, as it causes nausea , vomiting , diarrhea of acute poisoning is possible .

When applied topically to entire integuments, iodine absorption is minimal, while the use of Yox spray in the oral cavity leads to more pronounced and systemic absorption of iodine, as a result of which interference with thyroid functions may occur.

Contains approximately 18.6% ethanol .

Yox overdose, symptoms and treatment

If the drug was swallowed, acute poisoning developed - a metallic taste was felt in the mouth, digestive disorders occurred - vomiting, stomach pain, diarrhea. Anuria, swelling of the glottis followed by asphyxia, aspiration pneumonia, or pulmonary edema were noted within 1–3 days. In some cases, significant circulatory disorders were noted. Treatment is symptomatic: standard measures to prevent absorption of the drug are ingestion of activated carbon and 1-5% Na-thiosulfate solution to convert iodine into iodide. Reception of milk and starch mucus is indicated. There is no specific antidote.

Analogs

Level 4 ATX code matches:
Falimint

Suprima-ENT

Ingalipt-N

Strepsils Plus

Strepsils

Ingalipt

Theraflu LAR

Hexoral Tabs

Lisak

Efizol

Angilex

Kameton

Anzibel

Agisept

Lugol's solution with glycerin

Lugol

Laripront

Stopangin 2A

Stopangin

Septolete Neo

• Agisept;
• Aqua Maris;
• Angilex-Health.

Reviews about Yox

The drug is popular today, many note its effectiveness and always keep it in their home medicine cabinet.

Patients leave positive reviews about Yox, pointing out the convenience and ease of use of the aerosol and the speed of onset of the therapeutic effect (within 24 hours). Of course, there are patients who prefer traditional rinses, where Yox, thanks to its active substances, is effective in various inflammatory and infectious processes of the oral cavity and larynx.

You can find a few negative reviews about the drug associated with adverse allergic reactions: itching, burning, lacrimation.

Pharmacological properties

Pharmacodynamics

Yox-Teva is used to treat diseases of the oral cavity and ENT organs. It contains active substances that have anti-inflammatory and antiseptic effects due to the release of iodine when the solution comes into contact with the skin or mucous membranes. The drug has a wide range of effects on microorganisms; it is active against viruses, bacteria, fungi and protozoa.

Pharmacokinetics

Pharmacokinetic data for Yox-Tev are not provided.

Yox price, where to buy

The price of Yox spray (30 ml) is 265-325 rubles, solution (50 ml) – 165-205 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Yoks-Teva spray for local use.
  approx. 30mlTeva Czech Enterprises s.r.o. RUB 221 order
• Yox solution external 50mlTeva Czech Enterprises s.r.o.

  RUB 238 order

Pharmacy Dialogue

• Yox (50ml bottle)Galena

  RUB 211 order

• Yox (50ml bottle) Teva

  RUB 218 order

• Yox (spray 30ml)Ivax-CR

  RUB 269 order

• Yox (spray 30ml)Teva

  RUB 241 order

show more

Pharmacy24

• Yox 30 ml spray TEVA Czech Industries s.r.o., Czech Republic
  145 UAH.order

PaniPharmacy

• Yox liquid Yox spray 30ml, Teva Czech Industries

  148 UAH order

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Yox solution

The composition of the Yox solution includes the already known povidone-iodine, allantoin and propylene glycol.
Usually sold in 50 ml bottles. 1 ml of solution contains povidone-iodine 85 mg, allantoin 1 mg. The composition may also include levomenthol, citric acid monohydrate, sodium dihydrogen citrate, ethanol 96%, purified water. It is a transparent or translucent liquid, red-brown, with the odor of iodine. The solution is used to rinse the mouth for inflammatory and infectious diseases of the upper respiratory tract: sore throat, ARVI, pharyngitis, tonsillitis, glossitis, etc. To prepare a solution for rinsing, you need to dissolve half or one teaspoon of the solution in 100 ml of boiled warm water. Rinse no more frequently than every 4 hours. Do not swallow the solution! If an involuntary swallowing movement occurs, you can take several tablets of activated carbon (for preventive purposes). If the patient suffers from laryngitis, then Yox solution should be used for rinsing in case of urgent need. The solution is also used to wash the nasopharynx and palatine tonsils for adenoids and chronic tonsillitis.

Contraindications, period of use and interactions

Yox solution should not be used for hyperthyroidism, decompensated heart failure, or Dühring's herpetiformin dermatitis.
During pregnancy, Yox is contraindicated in any form. During lactation (breastfeeding) the drug is also prohibited. Children under 6 years of age should use other drugs as an antiseptic. A person’s allergy or sensitivity to the composition of the drug is also a reason to stop taking it. Since the composition contains alcohol, it is undesirable to use it for serious liver diseases and alcohol dependence. Yox solution for rinsing does not need to be supplemented with other antimicrobial drugs for external use. It itself is very effective. Treatment of complex diseases of the ENT organs is supplemented by the use of antibiotics. Usually 5-7 days of using the drug are enough to improve the patient’s condition or complete recovery.