The drug Klimadinon: instructions for use during menopause in women

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Manufacturers: Bionorica AG

Active ingredients

• Not indicated. See instructions

Disease class

• Other types of ovarian dysfunction
• Menopause and menopause in women

Clinical and pharmacological group

• Not indicated. See instructions

Pharmacological action

• Antimenopausal
• Estrogen-like

Pharmacological group

• Estrogens, gestagens; their homologs and antagonists in combinations

The drug Klimadinon

The drug Klimadinon, like many other drugs, is intended for use during menopause in women.
This medicine is not a hormonal type of drug.

The big advantage is that the composition is based on herbal and natural ingredients, which, of course, is very attractive to women.

Klimadinon is intended for cases when a woman is in menopause. The medicine helps alleviate the disorders that occur during menopause.

In other words, Klimadinon is a drug based on concentrated phytohormones. The medicine helps, first of all, to eliminate symptoms characteristic of menopause.

The drug can be taken for preventive purposes. This is permitted because the medicine is not a hormonal drug. Therefore, the volume of admission is not limited. However, this does not mean that the dosage is not required. The drug is in particular demand not only when a woman is in menopause, but also in cases where menstrual irregularities are noticed.

What are the phytohormones that form the basis of the drug? In fact, they can be classified as natural substances. As is known, such substances are harmless both for women and for their health.

The great advantage of such substances is that they are identical to human hormones. Some plants contain phytohormones.

Black cohosh extract is the main component of such medications . If you look at the composition of the medicine, then this extract is the active substance. This component contains the most important hormone necessary for women - estrogen.

This hormone plays an invaluable role in the regulation of menstrual cycles. As you know, everything in a woman’s body is very interconnected. The menstrual cycle, menopause and the organs responsible for the female reproductive system are directly intertwined.

Failure in the menstrual cycle, as well as the lack of functioning of the reproductive organs and the lack of the necessary hormone estrogen entails favorable conditions for menopause, as well as the menopause.

Effect on the body

As you know, every woman goes through menopause.
During this period, hormonal levels begin to decrease. This is especially true for sex hormones. As a result of this process, the balance in the body is disrupted, ultimately leading to imbalance.

Hormonal imbalance contributes to the development of symptoms inherent in menopause. The woman begins to feel hot flashes, headaches, malaise and a deterioration in general health.

estrogen begins first .

It is thanks to the process of hormone replenishment that all symptoms that cause women discomfort are eliminated.

When menstruation is disrupted, a hormonal imbalance occurs in a woman’s body. In this case, Klimadinon is well suited for smoothing out the cycle and restoring menstruation to its previous regime.

In both cases, Klimadinon is a medicine manufactured and released on the basis of herbal components that help balance a woman’s hormonal levels.

The effect of the drug is gradual. Don't expect instant results. Two weeks after the start of treatment, you can notice a favorable result.

If there is a need to achieve the fastest possible result, then hormonal medications will help. However, it is necessary to remember about a rather large list of side effects that can occur both during and after taking the hormonal drug.

Features of Klimadinon Uno

During menopause, against the background of hormonal changes, psychoemotional, neurovegetative and other changes occur that negatively affect well-being. The drug Klimadinon Uno is prescribed for pronounced disorders, since reviews from experts suggest that its effect is more active and intense than that of representatives of this line of drugs.

What happens to the body during menopause?

During menopause, an increased effect on the receptors of the hypothalamus begins, and they, in turn, respond to this in the form of a decrease in the production of GNRH (gonadotropin-releasing hormone). After this, the pituitary gland reduces the synthesis of luteinizing hormone and its concentration in the blood, while the ovaries reduce the synthesis of estrogen hormones and their content in the body. This relationship of the so-called triangle contributes to the destabilization of the psycho-emotional state and neurovegetative disorders.

The symptoms of this process are expressed by irritability, neuroses, loss of strength, hot flashes, sudden changes in body temperature and blood pressure, rapid heartbeat, pain, and dizziness.

How does the drug help?

At this point, this remedy comes to the rescue, equalizing the balance of hormones and eliminating the symptoms of menopause or significantly reducing their manifestation. Its greatest effectiveness is expressed in its sedative effect and relief of neurovegetative disorders.

Klimadinon Uno allows you to maintain hormonal levels during menopause, and also helps to avoid its sharp surges, which cause symptoms during this difficult period.

For a quarter of a century, foreign and domestic specialists have been using the drug with great success not only to alleviate the symptoms of menopause, but also to prevent diseases and adapt the body after drug-induced menopause or removal of the ovaries.

What is the composition?

Klimadinon UNO is a completely natural product of plant origin, like all representatives of this line.

The main active ingredient of the medicine is cosimifuga rhizome. The main difference between the product and Klimadinon is the concentration of this component. In this case, its content in one tablet is 6.5 mg.

The components of cohosh rhizomes act through estrogen receptors and are their modulators, without affecting the vaginal epithelium and endometrium, which, unlike hormonal drugs, does not provoke the development of hormone-dependent neoplasms.

This extract has been actively used since ancient times in the fight against female ailments, easing menstrual pain and regulating hormonal disorders, as it successfully demonstrates an estrogen-like effect.

Its important feature is not only the relief of symptoms, but also the solution to the problem at the root. The drug has a hormone-like effect on the body, without causing those side effects that synthetic hormones are famous for.

Cosimifuga is also known for its rejuvenating effect, which women can note both from the inside and outside.

The composition of the medicine has ideally selected proportions and concentrations of the plant component, therefore, along with efficiency, it has a gentle effect on the body.

Instructions for use

As you know, each medication has its own instructions for administration and dosage. This is an important point in therapy.

First, dosing influences treatment outcome as well as effectiveness. Secondly, the frequency of taking pills is extremely important. First of all, it builds a regimen, as well as the effectiveness of the effect on the body.

As already mentioned, you cannot choose the dosage of medications yourself, just like the mode of medication consumption. Moreover, varying the amount of consumption and dosing on your own is highly prohibited.

Klimadinon is a non-hormonal drug; it is recommended to consult your doctor for the choice of consumption and dosage regimen.

However, the drug is available in both drop and tablet form. Administration differs due to the form of the drug.

In drops

If the form of drops of the drug Klimadinon is chosen, then according to the instructions, it is necessary to take the medicine in the morning and evening, thirty drops.

In tablets

If you choose the drug in tablet form, then you need to take one tablet twice a day - morning and evening.

Klimadinon Uno

Klimadinon Uno differs in administration from previous forms of the drug.
Klimadinon Uno must be taken once a day. It is recommended to choose either morning or evening time to take the drug.

It is better to choose a specific time at which to take the medication. It could be 8 am or 6 pm.

When taking a tablet, you need to drink it whole with water.

The course of treatment must be continued until the symptoms accompanying the menopause completely disappear.

Use during pregnancy

The drug should not be taken during pregnancy. If signs of pregnancy are noticed, you must immediately stop taking the medication.

During lactation it is prohibited to take the drug. This is explained, first of all, by the fact that the active substance can be produced together with mother's milk. It is better to stop taking the medicine.

Reception for mastopathy

Despite the fact that taking Klimadinon is not an indication for use in a disease such as mastopathy, doctors are actively using this medicine.
The thing is that mastopathy is preceded by the same causes and symptoms that cause menopause.

According to statistics, in the case of long-term use of Klimadinon, 30% of women experience the disappearance of not only symptoms, but also diseases. In 70% of women, the development of the disease stops and stops progressing further.

Therefore, as practice shows, climadinon can also be used for mastopathy.

For successful therapy, you need to take one tablet twice a day or take thirty drops also twice a day. The course of treatment must be extended from two to three months.

Klimadinon

Klimadinon is an original anti-climacteric herbal medicine based on black cohosh rhizome extract from the German pharmaceutical company. Climacteric syndrome and all the accompanying unpleasant phenomena of a physiological and psychological nature that arise during menopause inevitably await every woman aged 42-55 years. Menopausal hormonal “swings” are accompanied by increased irritability, fatigue, headache, sleep disturbance, sinusoidal changes in blood pressure, heart rhythm disturbances, hyperhidrosis and hot flashes. To mitigate the effects of menopause, there are currently a number of effective medicines, one of which is the herbal preparation climadinone. The advent of herbal remedies based on estrogen-like substances allowed women to expect the onset of menopause without shuddering. Herbal extracts can not only reduce menopausal symptoms, but also improve metabolic processes in bone tissue. Cosimifuga rhizome extract, the active component of climadinone, has all these abilities. The healing properties of cohosh have been used by humans since ancient times. This plant has a hormone-like effect, choosing the anterior lobe of the pituitary gland as its site of action: the direct participation of cohosh extract ensures a decrease in the secretion of luteinizing hormone. Klimadinon, like estrogen, affects the vaginal mucosa, softens the symptoms of menopause and has a positive effect on bone tissue. Phytoestrogens from black cohosh have a dopaminergic organoselective effect on the woman’s body. An assessment of the therapeutic effectiveness of climadinon in patients with menopausal syndrome showed that the drug has the most positive effect on the lipid profile, harmonizing the levels of “good” and “bad” cholesterol (HDL and LDL, respectively). Pharmacotherapy using climadinone helps normalize bone mineral density, thereby preventing the development of osteoporosis.

In studies, climadinone has demonstrated a positive effect on biochemical markers of bone metabolism and mineral density of all problem areas of the femur. During clinical trials of the drug, it was found that its combination with moexipril in patients with arterial hypertension in the postmenopausal period leads to a decrease in blood pressure in 75% of women. At the same time, in patients taking moexipril as monotherapy, this figure did not exceed 50%. During the study of climadinon, an assessment of the density of the mammary glands was also carried out. Based on 140 mammograms, no increase in breast density was noted, with the exception of one patient with initially high breast density. Klimadinon has a beneficial effect on the endometrium. His condition was assessed through a biopsy, which confirmed the stimulating effect of the drug on endometrial thickness. In addition to all of the above, it must be added that climadinone has sedative properties, which is also not superfluous during menopause.

Klimadinon is available in two dosage forms: tablets and drops for oral administration. The therapeutic effect of the drug appears gradually and becomes pronounced in the third week from the start of treatment. Tablet dosage regimen: 1 tablet 2 times a day, morning and evening. Drops dosing regimen: 30 drops 2 times a day in the morning and evening. You should try to take the drug at the same time. The duration of the medication course in all cases is determined by the doctor. Without consulting a specialist, climadinon can be taken for no more than 3 months. The onset of pregnancy is a reason to stop taking the drug and consult a doctor. Patients suffering from diabetes mellitus should be informed that a single dose of climadinone contains less than 0.04 carbohydrate units.

Klimadinon or Mastodinon?

What is better to choose, Klimadinon or Mastodinon? Many women ask this question.

You shouldn't make decisions on your own. If we talk about drugs, it should be noted that the manufacturer is the same.

A pharmaceutical company builds its work on the basis of the production of medicines or herbal components that have an exclusively positive effect on health during therapy.

Side effects

Of course, despite the fact that the drug Klimadinon is not a hormonal drug, side effects also occur. Before you start taking the drug, you need to read the instructions, which describe in more detail how and in what form side effects may occur.

Accordingly, you need to know how this can affect your health and existing diseases. This is extremely important. Trying to cure one thing, you can cripple something completely different.

Side effects include:

• A sharp increase in body weight. As you can see, even non-hormonal drugs can contribute to weight gain. It is necessary to treat this fact with caution, observing the regimen and dosage of the medicine.
• Increased sensitivity of the nipples, as well as pain in the mammary glands. One of the symptoms that is quite rare. If, while taking the medication, you feel increased sensitivity over time, as well as pain in the mammary glands, then it is best to consult a specialist. Each woman may have a different reaction to the drug, as well as the manifestation of pathology, which the woman herself is not aware of.
• Discharge with blood from the genital tract. One of the side effects that is quite difficult to recognize. Women often confuse menstruation with menstruation, whether it occurs plannedly or suddenly.

The listed symptoms are not dangerous and go away on their own. As you can see, the list of side effects is not long.

Contraindications and side effects of the drug

This medication has no significant contraindications because it is made on a natural basis.

However, it is recommended to take it with caution for people with allergic reactions to the components of the product or with suspected neoplasms. In this case, it is taken only under the supervision of doctors.

Diabetics are not prohibited from using the medication, since it contains a minimum amount of sugar and bread units - 0.01 XE.

The medication is contraindicated for pregnant women and breastfeeding women, as well as for patients with epilepsy, endometriosis, and liver diseases. The presence of uterine fibroids during menopause is also a reason to change the medication.

Does not affect concentration and ability to operate machinery.

Concurrent use with estrogen-containing drugs is not recommended.

Side effects of a homeopathic remedy can include stomach pain, indigestion, diarrhea, flatulence, uncharacteristic menstrual bleeding (more often with an overdose), all kinds of allergic reactions, and weight gain. At the beginning of 2021, side effects of the line of these products were detected in 4% of female representatives, and in Klimadinon UNO - in only 2%.

Contraindications

As with any other medicine, when taking climadinone, there are a number of contraindications which, of course, should be familiarized with in advance.

Contraindications include:

• Presence of neoplasms. It is worth noting that contraindications are those neoplasms that depend directly on the hormone estrogen. Before starting treatment, of course, it is necessary to understand the nature of the tumor.
• Sensitivity to the use of lactose. In case of individual lactose intolerance, taking the drug is prohibited.
• Hypersensitivity to the components of the drug. If you are hypersensitive to the components that form the basis of the drug, an allergic reaction is possible.
• Patients with liver disease, epilepsy, and brain pathology are also prohibited from taking the drug.

Oral tablets Klimadynon Uno

Instructions for medical use of the drug

Description of pharmacological action

Klimadinon® Uno has an estrogen-like effect, exhibits sedative properties, and has a therapeutic effect on the autonomic nervous system. The use of the drug helps to weaken or completely disappear the symptoms of malaise during menopause. The therapeutic effect of Klimadinon® Uno occurs gradually and appears after approximately 2 weeks of treatment.

Indications for use

Vegetovascular and mental disorders in pre-, menopause and postmenopause (flushing, increased sweating, sleep disturbance, increased excitability, mood changes, apathy, etc.).

Release form

film-coated tablets; blister 15, cardboard pack 2; film-coated tablets; blister 15, cardboard pack 4; film-coated tablets; blister 15, cardboard pack 6; Composition Film-coated tablets 1 tablet. dry extract of cohosh rhizome (Cimicifuga racemosa L.) 32.5 mg contains 20% (6.5 mg) cohosh rhizomes native extract (4.5–8.5:1, extractant - ethanol 60% by volume) lactose monohydrate - 58.5%; cellulose - 19.5%; silicon dioxide - 2% excipients: cellulose powder; highly dispersed silicon dioxide; lactose monohydrate; magnesium stearate; corn starch; calcium hydrogen phosphate dihydrate; sodium carboxymethyl starch (type A); methylhydroxypropylcellulose (hypromelose); macrogol 4000; titanium dioxide (E171); iron oxide red (E172); iron oxide yellow (E172) in a blister 15 pcs.; There are 2 blisters in a box.

Pharmacodynamics

Klimadinon® Uno has an estrogen-like effect, exhibits sedative properties, and has a therapeutic effect on the autonomic nervous system. The use of the drug helps to weaken or completely disappear the symptoms of malaise during menopause. The therapeutic effect of Klimadinon® Uno occurs gradually and appears after approximately 2 weeks of treatment.

Pharmacokinetics

Data on the pharmacokinetics of the drug Klimadinon® are not provided.

Use during pregnancy

Should not be used during pregnancy. Breastfeeding should be stopped during treatment.

Contraindications for use

- individual hypersensitivity to the components of the drug; - lactose intolerance; - cannot be used to treat patients with estrogen-dependent tumors; - pregnancy; - lactation. With caution: impaired liver function. Patients who have previously had liver disease should consult a doctor before taking the drug.

Side effects

In rare cases, temporary stomach pain and allergic reactions to the components of the drug are possible.

Directions for use and doses

Inside. 1 table each 1 time per day along with a small amount of liquid and, if possible, at the same time of day (morning or evening). The drug should not be taken for more than 3 months without consulting a doctor.

Overdose

In case of an overdose of Klimadinon® Uno, complaints of stomach pain indicated in the section “Side effects” may be more pronounced. In this case, you should stop taking the drug and consult a doctor.

Interactions with other drugs

Interactions with other drugs are currently unknown.

Special instructions for use

When prescribing the drug to patients with diabetes, it should be taken into account that 1 coated tablet contains 0.01 XE. The drug in recommended doses does not affect the ability to drive vehicles and operate mechanisms that require increased attention. In case of disturbance or resumption of menstruation, as well as in case of prolonged or other newly arising complaints, it is necessary to consult a doctor, because we may be talking about diseases that require medical consultation.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 °C.

Best before date

24 months

ATX classification:

G Genitourinary system and sex hormones

G02 Other drugs for the treatment of gynecological diseases

G02CX Other preparations for use in gynecology

Interaction with other drugs

Often, during the treatment period, women are prescribed a large volume of medications. Not all medications can “get along” with each other.

This is explained by active substances that have the ability to displace each other and for this reason, upon completion of therapy, the result will not be comforting.

Before using the drug, it is necessary to find out in advance about the interactions of drugs if several more are taken in addition to the prescribed one.

As such, there are no prohibitions regarding “conflicts” with other medicines. If you are taking any medications for a long time, you must inform your doctor.