Methyluracil suppositories in gynecology: instructions for use, reviews and how much do they cost?

Treatment of female diseases is a very long and complex process, which involves a large number of different medications. Doctors are trying to use the most effective drugs for this purpose, working independently or in combination. Numerous representatives of this group include methyluracil suppositories.

Description of the drug

The drug, containing the active ingredient dioxomethyltetrahydropyrimidine, is indicated for topical use.

Available in the form of tablets, suppositories, powders and ointments, it has regenerating, anti-inflammatory, anabolic, immunostimulating and wound-healing effects.

Fast:

restores and normalizes the level of leukocytes in the blood;
normalizes metabolism;
accelerates the maturation of epithelial cells;
nourishes and saturates tissues.

The drug in the form of suppositories is harmless, relieves symptoms of inflammation, has a mild and gentle effect, and does not lead to irritation.

It is suppositories that are more relevant and are often prescribed to patients with hemorrhoids and many gynecological diseases.

Conclusion

It is important not to forget that the effect of methyluracil is expressed only in complex therapy. It is not an independent therapeutic agent, despite its main effect - stimulation of active cell recovery and growth. The affordable price combined with the high effectiveness of the drug allows it to remain the most popular for use in the treatment of gynecological diseases.

Sources

https://ogemore.ru/metiluracilovye-sveci-v-ginekologii/
https://woman-centre.com/preparaty/metiluracil.html
https://zdravcity.ru/p_metiluracil-supp-rekt-500mg-n10-0007509.html
https://gorzdrav.org/catalog/metiluracil/
https://medikamenty.guru/mochepolovaya-sfera/metiluratsil-instruktsiya-po-primeneniyu-v-ginekologii.html
https://mdiagnoz.ru/svechi-metiluracil-v-ginekologii-instrukcija-po-primeneniju.html
https://tabletochka.su/medicine/others-m/metiluracil-svechi.html
https://med-atlas.ru/boli-v-yaichnikax/svechi-metiluratsil-v-ginekologii-osobennosti-primeneniya.html
https://MedProstatit.ru/metiluracil-svechi.html

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Properties of suppositories with methyluracil

Creamy white T-shaped suppositories are especially considered effective rectal suppositories or stimulants for the regeneration of vaginal walls and tissues. Recommended for use in many diseases.

Suppositories containing the active substance - methyluracil:

relieve inflammation;
stimulate and renew epithelial cells;
have an anabolic effect;
heal affected tissue areas;
increase local immunity;
activates the production of leukocytes and erythrocytes in the blood;
synthesize immunoglobulins;
kill pathogenic microflora in the vagina and anus;
lead to the complete death of bacteria, namely their protein structures.

Methyluracil suppositories have proven their effectiveness in eliminating gynecological ailments. The active components quickly dissolve upon administration due to optimal body temperature and are absorbed into inflamed tissue areas, having a beneficial effect on the vaginal area.

Pharmacodynamics

Suppositories with methyluracil are presented as rectal, vaginal, flat, torpedo-shaped suppositories of a beige-yellow hue. The drug is packaged in separate metal blisters of 10 pieces, placed in a cardboard case.

Dioxomethyltetrahydropyridimine, which is part of the structure of rectal suppositories, is an organic chemical compound found in nucleic acid.

Possessing immunomodulatory and photoprotective qualities, the organic element promotes the regeneration of cell-tissue structure, normalizes nutritional processes, the quantitative composition of erythrocytes and leukocytes, and improves the hemostatic properties of the mucosa.

Operating principle

The suppositories are actively absorbed into the rectal mucosa and within 15-20 minutes from the start of use, the active components are present in the blood plasma. The highest concentration is observed 1.5 hours after penetration.

The drug begins to quickly stimulate and activate cellular protective mechanisms, provide an anti-inflammatory, analgesic and wound-healing effect.

Methyluracil:

leads to stimulation of many mechanisms in the body;
restores and regenerates the vaginal mucosa at the cellular level;
leads to the rapid formation of new cells and the growth of normal tissue, no different from the surrounding layers;
synthesizes blood cells;
promotes the formation of a new epithelial layer;
heals ulcers and cracks;
reduces pain;
improves cellular metabolic processes;
accelerates the restoration of destroyed layers when rough scars have already formed in the vagina;
boosts the immune system.

The main purpose of methyluracil is to relieve inflammation and eliminate unpleasant symptoms. It is the suppositories that promote rapid healing and resorption of scars and have a destructive effect on proteins secreted by bacteria. Thus, the introduction of pathogenic microflora into the mucous membrane is stopped.

Suppositories are quite applicable in combination with other local drugs and do not affect the weakening (increasing) of their properties. This is important when using drugs with methyluracil by women during pregnancy and lactation.

Drug interactions

Methyluracil suppositories are compatible with sulfonamide agents, antiseptics and antibiotics; no negative reactions were detected during their interaction. Due to the methyluracil content, when taking the drug simultaneously with cystamine, the anti-radiation effect of cystamine is enhanced. In other cases, taking a suppository does not affect the effectiveness of other drugs in any way, so it can be taken simultaneously with many medications.

Indications for use in gynecology

Suppositories are the most common form of prescription by gynecologists for damage to the outer part of the cervix or vaginal mucosa, since they have a gentle effect on tissues and cells, evenly release active substances and are easy to use. It is enough to follow the instructions and observe the dosage.

Candles do not require any special conditions for use and do not lead to adverse reactions.

Can be used in combination with antibiotics and other therapeutic methods. They are acceptable for use during pregnancy because they are not absorbed into the bloodstream and do not have a negative effect on the fetus.

Methyluracil in the suppository:

heals wounds and stitches well;
regenerates tissue in the vagina;
eliminates inflammatory processes;
restores cellular structures during erosion or after illnesses on the cervix, when small damaged areas of the mucous membrane are observed and infiltrate begins to be released, leading to complications.

Candles are indispensable for use after such harsh techniques as cauterization, electrocoagulation, endocervicosis.

Doctors often prescribe drugs for external use after gynecological operations, for injuries of the vagina and cervix, as well as diseases (vaginitis, cervicitis, vulvitis, cystitis, leukoplakia).

Suppositories are indicated for use by older women at the onset of menopause, when age-related changes are observed and it is simply necessary to increase the elasticity and strengthen the vaginal muscles.

Use for hemorrhoids

Rectal methyluracil suppositories are often prescribed by proctologists for the treatment of hemorrhoids, fissures in the anus, and various injuries in the sigmoid colon.

Suppositories not only relieve many diseases, but also eliminate constipation and are also useful for the prevention of intestinal disorders.

The medicine helps:

cell renewal;
healing of wounds and cracks in the anus;
restoration of damaged mucosa;
eliminating unpleasant signs.

Suppositories for hemorrhoids are suitable for use during pregnancy and will not lead to a negative effect on the fetus; it is enough to carefully insert into the anus to a depth of the index finger.

To avoid spreading, candles can be stored or kept in the refrigerator before use.

Before starting a treatment course, you need to:

empty your bowels and go to the toilet;
wash the anus using hygienic soap;
lightly wipe the anus with a soft towel;
take a position lying on your side, bending your knees for easy insertion;
wait 0.5 hours for better absorption of active substances.

It is advisable to use candles at night. If it is necessary to carry out procedures in the morning, it is not recommended to get out of bed immediately. It’s better to lie down for a while and wait until the candle is completely absorbed.

Mode of application

It is important to follow the regimens and doses prescribed by the doctor, and also follow the instructions without neglecting the instructions. You can administer up to 4 suppositories per day and no more than 2 in 1 session.

Rectal suppositories are indicated for vaginal administration in the treatment of gynecological diseases. Before use:

carry out hygiene procedures, douche with the addition of a weak solution of potassium permanganate or iodine;
then carefully insert the suppository into the vagina, lie down for 15-20 minutes in a relaxed state;
Allow the suppositories to distribute evenly throughout the vaginal cavity and gradually melt.

The treatment course can vary from 10 to 60 days, so it is better to first consult a doctor before use.

Attention! For virgin girls, suppositories are used exclusively rectally.

Features of use during pregnancy and breastfeeding

Many women with the onset of pregnancy experience trouble with itching and burning in the anus, when hemorrhoids or, for example, cervical erosion are diagnosed.

You should not experiment on yourself using methyluracil suppositories during pregnancy or breastfeeding without instructions.

Even such gentle drugs as suppositories with methyluracil can cause serious harm instead of benefit and expose the fetus to risks.

Although pregnancy and breastfeeding are not considered contraindications for the use of methyluracil, and are often prescribed to women if it is necessary to treat gynecological diseases such as colpitis, cervical erosion, vaginal dysbiosis, vaginitis, vulvitis, without waiting for childbirth or the end of the lactation period.

Of course, it is not recommended to use suppositories yourself at home without a doctor’s recommendation.

Instructions for use

It is important to understand that almost all gynecological diseases lead to damage and inflammation of tissue in the vagina, the accumulation of bacteria and microbes, in particular their decay products.

The body experiences stress and begins to react inadequately to such processes. Pathogenic flora begins to accumulate in the vaginal mucosa and ooze out in the form of serous discharge.

In order to increase the effectiveness of the treatment course, before using methyluracil suppositories, it is advisable to treat the vaginal cavity by moistening cotton swabs with antiseptics and gently wiping away mucous accumulations.

If the candles are stored in the refrigerator, you must first rub them in your hands so that they are at room temperature. Next, wash your hands with soap to avoid further infection. Remove the suppositories from the packaging, insert them as deeply as possible into the vagina, holding with 2 fingers and leading from the back wall of the vagina.

If suppositories are used rectally, it is first recommended to give a cleansing enema, then cover the vagina with gauze or a pad so as not to stain the underwear.

The main thing is to act according to the instructions and properly clean the tissue surface of the vagina from any secretions to quickly achieve the effect. After which you need to remain in a lying position for 0.5 hours. The number of procedures performed and the duration of the treatment course are selected by the doctor on an individual basis.

On a note! It is not advisable to use methyluracil suppositories during menstruation and you should refrain from carrying out the procedures and choose another time for treatment. It is also recommended to avoid intimacy so as not to further disturb the damaged vaginal mucosa.

Suppositories can be used in combination with other medications. If unpleasant signs appear after using methyluracil, it is better to consult a doctor. Replacement with other analogues is possible.

Analogs

If for any reason the use of methyluracil suppositories is prohibited, you can consult your doctor about treatment with a medicine that is an analogue of this drug. In medicine, almost every medicine has an analogue. The composition of the medications is different, but the effect is the same. Analogues of methyluracil include drugs such as Meturacol, Stizamet, Aescusan, Biostrepta, Esculex, Softovak, Prelax. Individual recommendations from a specialist will help you choose an analogue that is ideal for you.

Possible side effects

Often, with excessive sensitivity to the components of methyluracil, women experience allergic reactions.

Also, suppositories can lead to short-term symptoms:

burning;
itching;
irritation;
dryness of the vaginal mucosa;
hives;
headache;
drowsiness;
dizziness, although the symptoms should not last long and will probably go away quickly on their own. In general, suppositories are well tolerated and side effects are rare.

Methyluracil has a sedative effect, which leads to apathy and fatigue. It is better to stay at home during treatment or wait until the effects of the drug have completely stopped. If such effects occur, it is better to stop use and consult a doctor.

Overdose

Overdose of the drug occurs extremely rarely. The product has virtually no side effects and is well tolerated by the body. It is recommended to strictly follow the dosage prescribed by a specialist.

When using more than 5 suppositories daily for a long time, redness of the mucous membrane, itching, burning, and dryness of the vagina or rectum may occur. If these symptoms are detected, you must immediately stop the drug, take a shower, administer an enema (with anal administration), take a sorbent and an antihistamine.

How to take it correctly?

Usually the duration of the treatment course is 7-14 days. But only the doctor monitors the treatment process and the degree of recovery; if necessary, he can adjust the regimen, extend the treatment course if necessary, or add other drugs with increasing doses.
Methyluracil for gynecological diseases is usually used according to the standard regimen: 1 suppository up to 4 times a day by vaginal or real administration.
It is undesirable to use suppositories on your own without consulting a doctor, thereby self-medicating. Although suppositories are sold in pharmacies without a prescription and do not lead to any particular side effects.
Before treatment, it is important to first identify the cause of the pathology , as well as the causative agent that caused it. Candles should not be used unless prescribed. To achieve better absorption, the procedures must be carried out in a lying position by inserting the suppository as deeply as possible.
When douching, you can use antiseptics: soda, Chlorhexidine or herbal remedies. To avoid staining your laundry, it is advisable to use candles at night and use sanitary pads.

The duration of the training course depends on the severity and neglect of the disease:

So, when treating erosion or mechanical damage to the mucous membrane of the cervical canal, 1 suppository is used 2 times a day, the treatment course is 2 weeks.
For vulvitis, the drug is administered vaginally at night. The duration of the treatment course is up to 1 month.
Girls from 3 to 8 years old can use 1/2 a candle once a day. To make the procedure easier, your fingers can be treated with sterile Vaseline oil.

The dosage directly depends on the disease and age of the patients:

for adults - 0.5 g 4 times a day
for children from 3 to 8 years – 25g
children from 8 to 15 years old - 0.5 g.

The course of treatment is approximately 7 days - 1 month, but extension is possible if necessary, taking into account test results and at the discretion of the attending physician.

Patient reviews

Ivan . The doctor prescribed Methyluracil suppositories to treat prostatitis. I would never have thought that ordinary candles could help in such a delicate matter, but after a week I felt relief. The urge to urinate has decreased. But I wanted to give up this treatment altogether, it’s good that my wife insisted. The doctor said that in 6-8 weeks he would bring me back to normal.

Valentina . I used candles after cauterizing the erosion. A gynecologist friend advised me and said that healing would be faster. And indeed, she turned out to be right. The course lasted 7 days in total, I put 1 suppository at night. An excellent product, I will recommend it to my friends.

Catherine . A proctologist prescribed suppositories for me. After childbirth, constipation often occurred and, as a result, an anal fissure formed. Fortunately, at least I didn’t suffer from hemorrhoids. Everything healed quickly, and things got better with bowel movements. Now I try to prevent such conditions, but just in case I always keep this magical remedy in my medicine cabinet. You never know.

Is it possible to continue treatment during critical days?

Suppositories are so harmless to the female body that even when used on menstrual periods they will not cause much harm. It can be used by women during pregnancy or lactation. But it is important to understand that menstrual flow significantly reduces effectiveness.

The candles do not have time to be absorbed, and most of them flow out. It is unreasonable to expect a positive and quick effect in this case. Still, it is better to start a course of treatment that does not coincide with the arrival of the next menstruation.

If sudden and unexpected discharge occurs, it is reasonable to administer the suppositories rectally. With vaginal administration of suppositories, the effect of methyluracil will be significantly reduced.

You should not plan treatment for critical days. It is better to wait until this period ends or start using the drug rectally.

Price in pharmacies in Moscow, St. Petersburg, regions

Cost of the drug by region of Russia:

Methyluracil suppositories

Locality	Price, rub.
Moscow	57-120
Saint Petersburg	44-110
Kaliningrad region	44-100
Vologda Region	33-132
Voronezh region	70-102
Astrakhan region	24-81
Ivanovo region	60-105
Irkutsk region	36-125
Kaluga region	25-110
Lipetsk region	20-80
Penza region	30-115
Saratov region	25-90
Tambov Region	25-70
Tver region	24-69

The price factor varies depending on the region and retail pharmacy chain.

What can replace candles?

It is reasonable to replace methyluracil suppositories with other analogues, taking into account the composition of the active substances in the drugs, as well as the disease for which it is worth replacing.

Analogs are considered:

Klion-D containing miconazole and nitrate to eliminate pathogenic microflora in the vagina caused by fungus;
Viferon in the form of suppositories with the active substance - interferon Alpha, if necessary, provide antiviral, antiproliferative, immunomodulatory effects;
Immunofan containing tyrosine and arginine to provide detoxification, hepatoprotective, immunomodulatory and antioxidant effects;
Eucalyminum in composition with eucalyptus to relieve inflammation, eliminate bacterial flora;
Meturacol in the composition with the active substance - methyluracil to provide wound healing, anti-inflammatory, adsorbent effects;
Pyrogenal is composed of polysaccharides to provide immunomodulatory, antiallergic and regenerative effects.

Klion Viferon

Imunofan

Pyrogenal

Meturacol
If there are contraindications, the following analogues can be used:

Ultraproct;
Anuzol;
Relief;
Proctoglivenol;
candles with sea buckthorn oil;
preparations containing biologically active additives.

Relief

Ultraproct

Anuzol

Candles with sea buckthorn oil

Contraindications

Medicines based on methyluracil should not be used by children under 3 years of age. The drug should be used with caution by those who are allergic to any of its components, otherwise the result of therapy may be negative. You must inform your doctor if you have any chronic disease. Suppositories are contraindicated in patients suffering from one of the following diseases:

lymphogranulomatosis;
leukemia (chronic or acute);
malignant tumors.