pharmachologic effect
The drug blocks the effects of progesterone and the child dies from lack of nutrients and oxygen.
Mifeprex tablets are a synthetic steroid drug with an antigestagenic effect.
It blocks the effects of progesterone at the level of gestagen receptors without exhibiting gestagenic activity, as well as antagonism with glucocorticosteroids.
The use of Mifeprex tablets affects the myometrium and increases its contractility.
Due to this, sensitivity to myometrial prostaglanids increases, the strength of which depends entirely on the menstrual phase.
The drug Mifeprex slows down the ovulation process and possible changes in the endometrium of various types. This avoids implantation of an egg that has already been fertilized.
In the case of uterine leiomyoma, the therapeutic effect is achieved through the influence of sex hormones. For this reason, the result may differ for each woman, that is, the development of the tumor may slow down or the size of the uterus itself and fibroid nodes may decrease.
Possible complications
When the drug is used correctly under the supervision of a specialist, complications rarely develop. Sometimes there are menstrual irregularities, lack of ovulation, uterine bleeding, inflammatory pathologies of the appendages, pain during intercourse.
The most common complication is considered to be an incomplete miscarriage, when the fetus is expelled, but the fertilized egg remains. In this case, inflammation develops, the endometrium and myometrium are involved in the process, spotting and signs of intoxication appear.
If a woman ignores the symptoms and does not consult a gynecologist, the pathology can only be treated surgically.
Composition and release form
The drug Mifeprex is available in tablet form.
1 piece contains 200 mg of mifepristone.
Read about how to take Mifepristone here.
In addition to this substance, there are also auxiliary ones:
- Corn starch;
- Calcium stearate;
- Lactose;
- Microcrystalline cellulose;
- Calloidal silicon dioxide.
Photo gallery of substances:
Lactose Calloidal silicon dioxide Microcrystalline cellulose Calcium stearate
Corn starch
Sold tablets 3 pieces per pack
Indications for use
The drug Mifeprex is used not only for abortion. And even in this case, it is allowed to resort to using pills no later than the 42nd day of pregnancy.
The drug is also prescribed to women as:
- Medicines against uterine leiomyomas;
- A drug to induce labor during full-term pregnancy;
- An emergency method of contraception, which is used no later than 72 hours after unprotected intimacy.
Preparation rules
Before using the medicine, a woman must undergo a diagnostic examination in order to detect chronic pathologies and other possible contraindications that may complicate the medical abortion procedure.
It is necessary to donate blood for a general analysis, hormone levels and glucose levels. An ECG (electrocardiogram) and ultrasound (ultrasound) of the uterus are required to accurately determine the duration of pregnancy. A week before your appointment, you should not consume non-steroidal anti-inflammatory drugs or alcoholic beverages.
On the day of the manipulation, it is not recommended to drink strong coffee, tea, or eat fatty, smoked and salty foods in large quantities.
Contraindications
The drug is a hormonal drug, so it is simply impossible to ignore contraindications.
| No. | Category of contraindications | When should you not use Mifeprex tablets? |
| 1 | Are common | — Renal/liver failure in the acute period; — Long-term therapy with glucocorticosteroids; — Uterine fibroids; — Adrenal insufficiency; — Women who smoke, over 35 years old; — Presence of inflammation of the genital organs; - Porphyria; — Intolerance to any of the components; — Severe form of anemia; — Extragenital pathology; - Hemostasis disorders. |
| 2 | Medical abortion | - Pregnancy period exceeding 42 days; — Unconfirmed pregnancy; — Diagnosed/history of ectopic pregnancy; — Pregnancy during the use of intrauterine contraceptives, which were preceded by hormonal contraceptives. |
| 3 | Induction of labor | — Preeclampsia of severe type; — The position of the fetus in the womb is incorrect; - Eclampsia; — Preeclampsia; — Premature/post-term pregnancy; - During pregnancy, the presence of bleeding of unknown origin; — The mother’s pelvis is much smaller than the fetal head. |
| 4 | Leiomyoma of the uterus | — Breastfeeding period; — Pregnancy; — The size of the neoplasm is larger than a 12-week pregnancy; — Tumors on the ovaries; — Endometrial hyperplasia; — Myomatous nodes are in a submucosal location. |
Buy mifepristone and misoprostol tablets to terminate early pregnancy in Moscow
Dear residents of Moscow and the Moscow region , we are glad to see you on our website!
In our online pharmacy you can buy Mifepristone without a doctor’s prescription by placing an online order for medication abortion pills with home delivery at the lowest price.
We offer original, best quality and most effective abortion pills! Side effects from the drugs are zero, and the effectiveness is more than 99%. We have been working in this market for more than 5 years!
The set of drugs for early termination of pregnancy includes:
- Mifepristone (synonyms: Mifepristone, Mifeprex, Mifegin, Pencrofton), 200 mg or 600 mg.
- Misoprostol (synonyms: Cytotec, Cytotec, Cytotec) - (STADA, Germany), 400 mcg.
IMPORTANT! You buy exactly those original drugs that are indicated in the photographs!
You can place an order for abortion pills online directly from the website. We have the lowest price for Mifepristone and Misoprostov in Moscow; the current price list can be found here.
Estimated delivery time: to Moscow - 1 day, to the Moscow region - 1-2 days, starting from the day the order was accepted. Delivery is carried out by Russian Post or courier service directly to your door.
Benefits of pharmacological abortion
Every woman dreams of motherhood. This is not only great happiness, but also great responsibility. But there are times in life when an unplanned pregnancy is simply inappropriate. In such situations, many women resort to surgical termination of pregnancy, which causes various pathologies and often leads to infertility.
But this is not the only method of getting rid of an unwanted fetus.
In modern medicine, special medications have been developed that are used in early pregnancy (Mifepristone - Mifegin, Misoprostol - Cytotec).
This is a good alternative to surgery, in which there is no need for hospital treatment. Let’s look at what the medical abortion regimen is and what the result is in more detail.
The main advantage of a pharmacological abortion is that there is no need to go to the hospital.
In addition, anesthesia and instrumental intervention are not used, which have their own side effects.
According to experts, any termination of pregnancy has a negative effect on the body; it leads, first of all, to hormonal disorders, and the nervous system suffers.
But medical abortion is safer and easier for women not only physically, but also psychologically. After all, there is no risk of damage to the uterus.
But it cannot be said that this method does not have disadvantages, since even the most innovative and safe medicine has side effects. A medical abortion is an artificially induced miscarriage, which is accompanied by pain in the lower abdomen and bleeding.
Therefore, it is necessary to resort to this method only after consultation and under the supervision of a gynecologist, even if you have already used it once.
Conditions for using medical abortion
A prerequisite for the use of medical abortion is compliance with the deadlines. This method cannot be used if the pregnancy is more than 8 obstetric weeks, so you must first be examined to determine the exact period. If this procedure is carried out under the supervision of a gynecologist and all his recommendations are followed, everything will go well.
Side effects
Mifeprex tablets can cause some adverse reactions such as:
- Discomfortable sensations in the lower abdomen;
- Feelings of extreme weakness;
- Increased body temperature;
- Headache;
- Dizziness;
- Diarrhea;
- Nausea/vomiting;
- Rashes on the epidermis;
- Bleeding;
- Inflammatory process of the uterus/appendages;
- Exacerbation of infections of the uterus/urinary system;
- Failure of the menstrual cycle.
MIFEPREX
| Pills | 1 tab. |
| mifepristone | 200 mg |
3 pcs. – blister contour packages (1) – cardboard packs.
For impaired renal function
Contraindicated in acute or chronic renal failure.
For liver dysfunction
Contraindicated in acute or chronic liver failure.
The description of the drug MIFEPREX is based on the officially approved instructions for use and approved by the manufacturer.
Found an error? Select it and press Ctrl+Enter.
Source: https://health.mail.ru/drug/mifeprex/
Side effects
From the digestive system:
nausea, vomiting, diarrhea.
From the side of the central nervous system:
dizziness, headache.
From the reproductive system:
bloody discharge from the genital tract, menstrual irregularities, amenorrhea, exacerbation of inflammatory processes of the uterus and appendages, lochiometer, subinvolution of the uterus.
Allergic reactions:
hives.
Other:
feeling of discomfort and pain in the lower abdomen, weakness, hyperthermia.
Drug interactions
The combination of Mifeprex + Misoprostol provokes the development of:
- Vaginitis;
- Dyspepsia;
- Insomnia;
- Asthenia;
- Pain syndrome in the lower extremities, etc.
Photos on the topic:
Asthenia Pain syndrome Vaginitis Dyspepsia
Insomnia
If treatment requires the simultaneous use of Mifeprex tablets and glucocorticosteroids, the dosage of the latter should be increased.
Instructions for use
The drug Mifeprex is dosed depending on the reason for its prescription. It can only be used in specialized medical institutions.
| No. | Reason for using Mifeprex tablets | Dosage and features of using Mifeprex tablets |
| 1 | Medical abortion | All 3 tablets are used. They are consumed 1 or 1.5 hours after meals and washed down with water. For better effect, add 2 tablets of Misoprostol. If the miscarriage does not occur within 2 weeks, it is completed using the vacuum-aspiration method. |
| 2 | Induction of labor | 1 tablet is taken, and after 24 hours - 1 more. If the birth canal has opened sufficiently, another drug is used as the final stage of provoking labor. |
| 3 | Emergency contraception | 10 mg 2 hours before/after eating for 3 days. |
| 4 | Leiomyoma of the uterus | 1/4 tablet per day for 3 months |
Special Recommendations
Patients who use this pharmacological drug "Mifeprex" to terminate pregnancy through medication should know that if the medication does not have the desired effect within two weeks, and the pregnancy still continues, it must be terminated by another method, since there is a high probability of the formation of congenital malformations in development.
The use of the drug "Mifeprex" by patients with endocarditis of an infectious nature or artificial heart valves should occur in combination with antibacterial therapy. The medication is not able to prevent the development of sexually transmitted infections. The use of the drug as a permanent contraceptive is prohibited.
Analogues substitutes
The effects of this drug can be achieved using similar means:
- Agesta is a hormonal drug in tablet form. .
- Ginepristone has an antigestagenic effect and is available in tablet form. (Russia).
- Ginestril is a hormonal antigestagenic drug that is available in tablet form. (Russia).
- Zhenale is an antigestational hormonal drug in tablet form. (Russia).
- Mifegin acts as an antiprogestagenic drug. It is available in tablet form. Manufacturer: EXELGYN Laboratoires, MACORS Laboratoires (France).
Photos of analogues:
Zhenale Mifegin
Ginestril Ginepristone Agesta
Patient reviews
Maria, 18 years old : “It so happened that I became pregnant. When I told my boyfriend, he simply disappeared, as often happens. I have no parents and no one to help, so I decided to have an abortion. The time was very short, it wasn’t even a month. I was afraid to see a doctor and bought Mifeprex myself. I did everything according to the instructions, but the pain was just terrible. Then it weakened, but did not go away for a long time.”
Tatyana, 25 years old : “I had an abortion at a medical center. Everything went perfectly, without side effects or anything else. They also prescribed Mifeprex + Misoprostol tablets.”
Take this medication with caution
This drug is used with caution in patients with bronchial asthma, arrhythmia, obstructive pulmonary pathologies, arterial hypertension, and chronic heart failure. If these recommendations are not followed, serious complications may occur. This is confirmed by numerous reviews.
Those who have terminated a pregnancy with Mifeprex report that such an abortion is rare, but can have a negative impact on health.
