Indications and contraindications for use
The medication is prescribed for the prevention and treatment of inflammation and pain after surgery associated with the removal of cataracts.
Not everyone can use Nevanac drops. So, they are prohibited from using:
- children under the age of majority;
- mothers whose babies are breastfed;
- people who are intolerant to any component of the drug;
- women carrying a child.
After cataract removal, non-steroidal anti-inflammatory drops help avoid complications
Also, the drug should not be dripped into the eyes of people with the following pathologies:
- acute rhinitis caused by the use of acetylsalicylic acid or any other non-steroidal drug with anti-inflammatory properties;
- bronchial asthma;
- hives.
Patients with a history of predisposition to bleeding should use the medication only under medical supervision. The use of drops after surgery can trigger its occurrence.
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Dermatochalasis
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Reviews of the drug from ophthalmologists and patients
Reviews from doctors and patients who have undergone ophthalmic surgery allow us to get a more complete picture of eye drops.
Vladimir Ivanovich, 67 years old, Kostroma:
“Nevanac became the third drug prescribed by the ophthalmologist after phacoemulsification of cataracts. I instill it according to the regimen prescribed by the doctor in combination with two other drugs. The result is obvious: there was no inflammation, I am recovering quickly after surgery on both eyes. The bottle is easy to use; the built-in pipette makes it easy to dispense drops.”
Victoria Sergeevna, 56 years old, Voronezh:
“The attending physician prescribed the drug after cataract removal. I was very pleased with the quality of the drops. The operation is relatively painless, but on the first day the pain was quite disturbing. Nevanak successfully helped to cope with this. On the doctor’s recommendation, I used it for three weeks—one bottle was just enough. Before instillation, it is necessary to shake - the suspension gives sediment and becomes very thick. Very convenient pipette with dispenser. The second time the doctor prescribed drops for the treatment of conjunctivitis - they perfectly relieved the burning sensation and reduced tearing. The only drawback is the price, but you can’t save on your health. For the money this is an excellent result.”
The drops relieve itching and burning well.
Anna Ivanovna, ophthalmologist with 38 years of experience:
“Nevanac is usually prescribed before cataract surgery. Treatment continues in the postoperative period according to the scheme determined by the doctor for at least two weeks. The most effective way is the combined use of several medications. In some cases it is effective as an adjuvant. It relieves pain well and eliminates burning sensation. The drops have stood the test of time. In my practice, there have been no complaints about side effects or lack of results.”
Possible adverse reactions
While taking Nevanak eye drops, there is a possibility of side effects. There are a lot of them. Before using the drug, you should definitely read them. So, what unpleasant symptoms may appear:
- Photophobia.
- Itching and pain in the eyes.
- Sinusitis.
- Discharge from the eyes.
- Allergic conjunctivitis.
- Increased blood pressure.
- Eye irritations.
- Cataract.
- Dermatochalasis.
- Conjunctival hyperemia.
- Nausea, diarrhea and vomiting.
- Punctate keratitis.
- Blurred vision.
- Dry mouth.
- Choroidal protrusion.
- Extra strong tear production.
- Iritis.
- Formation of dry crusts in the corners of the eyes.
- Headache.
With increased sensitivity to the components, increased inflammation of the conjunctiva may occur.
Rarely, but still possible, adverse reactions such as:
- Scar formation on the cornea.
- The appearance of an inflammatory infiltrate in the anterior chamber of the eye.
- Damage to the cornea.
The occurrence of any of the above side effects is a valid reason to stop taking Nevanac.
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Active ingredient: diclofenac
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Nevanaka price, where to buy
You can buy Nevanak in many pharmacies in Moscow and other Russian cities. The price varies between 517 - 539 rubles per package.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
ZdravCity
- Nevanac eye drops 0.1% 5mlS.A.
Alcon-Couvreur nv RUR 638 order
Pharmacy Dialogue
- Nevanac (cap. vial 5 ml)Alcon SA
RUR 716 order
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Pharmacy24
- Nevanak 1 mg/ml 5 ml eye drops
281 UAH.order
PaniPharmacy
- Nevanac liquid Nevanac h/c 1 mg/ml 5 ml No. 1 Belgium, Alcon-Couvreur
297 UAH order
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Composition and release form
The pharmaceutical drug is available in the form of a suspension, yellowish in color, in a bottle with a dropper. Drop volume – 5 mm. Instructions are always included with the bottle.
The main active ingredient is Nepafenac. 1 ml of drops contains 1 mg of this component. In addition to it, they contain substances such as:
- tyloxapol;
- hydrochloric acid;
- carbomer;
- water;
- sodium chloride;
- disodium salt of ethylenediaminetetraacetic acid;
- mannitol;
- benzalkonium chloride.
The compact bottle is equipped with a convenient spout for proper instillation
Note to young mothers: massage for dacryocystitis of newborns.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The active substance is a non-steroidal anti-inflammatory drug with anti-inflammatory and analgesic effects . Penetrates through the cornea and is converted into the active form - amphenac , which inhibits the enzyme necessary for the production of prostaglandins. The use of the drug reduces pain and swelling of the eye tissues without affecting intraocular pressure.
Pharmacokinetics
Rapidly absorbed when applied topically. After daily use, low concentrations of the active substance are detected in the blood after 2 hours. Cmax of nepafenac in the aqueous humor of the eye is observed after 1 hour. The active substance has a high affinity for albumin and binding to them is 99%. Under the influence of enzymes, it undergoes hydrolysis to amfenac, which subsequently forms conjugates with glucuronic acid. In studies after oral administration, it was excreted by the kidneys (about 85%) and through the intestines (6%).
Instructions for use
The drug should be started the day before cataract surgery. You need to apply it 3 times during the day. The dosage is 1 drop in one eye.
Then, at least an hour before surgery, you need to drop another 1 drop into the eyes. After surgery, it must be used for 14 days. Instillation should be carried out three times a day, 1 drop.
It is not recommended to use it for longer than the prescribed period, as it can provoke negative reactions from the cornea. The use of contact lenses during treatment is prohibited. In addition, during therapy you should stay in the sun as little as possible.
Nevanac eye drops should be shaken before use.
A mydriatic used for diagnosis and treatment is Mydriacyl eye drops.
It is necessary to instill the product into the lower conjunctival sac
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Interaction
Studies have shown that the drug does not inhibit the activity of cytochrome P450, therefore there is no interaction with drugs that transform with the involvement of cytochrome P450. The simultaneous use of this drug and Prostaglandin or its analogues is not recommended, since there is no data on their simultaneous use. When used in combination with other drugs, it is necessary to maintain an interval of 5 minutes between instillations.
Analogs
If there are contraindications to the use of a medicine, then its analogues can be used instead.
- Diclofenac eye drops. These drops have fewer side effects, and they have the same effect. It should not be used only by children under 16 years of age, the elderly and women in the third trimester of pregnancy. The active substance is diclofenac.
- Oftan Dexamethasone. It has antiallergic and anti-inflammatory effects. Children and women bearing babies can use it, but only under the supervision of a doctor. Its use is prohibited for fungal and viral eye diseases, chicken pox and keratitis. The active ingredient is dexamethasone sodium phosphate.
- Diklo F. This medication has an anti-inflammatory effect, relieves pain and fever. It can be prescribed to children, but only when the benefits outweigh the possibility of adverse reactions. These include photophobia, blurred vision, itching, and burning eyes. The main substance is diclofenac sodium.
- Indocollier. Has an anti-inflammatory effect. Its use by children and pregnant women is allowed. The instructions for Indocollir eye drops say that it cannot be used by people who have diseases of the optic nerve, liver dysfunction and blood clotting. The active ingredient is indomethacin.
Cheap analogue
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NSAIDs for topical use in ophthalmology
When you see no further than 10-15 cm from the nose or what is high myopia.
Hormonal anti-inflammatory drug
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