Instructions for Nitrofungin (Method and dosage)
The medicine can be prescribed to adults and children over 15 years of age.
According to the instructions for use of Nitrofungin, it is applied to the affected areas of the skin or instilled into the ears 2-3 times a day. The product is not diluted, applied pointwise or rubbed into the skin.
After the signs of the disease disappear for a month, the drug is used as a prophylactic 1-2 times a week, 2-3 times a day.
As a rule, the solution is not diluted, but if severe irritation occurs or if necessary, the liquid can be diluted with water (one to one).
Side effects
When using Nitrofungin Neo, the treated surfaces may turn yellow or greenish. Considering that the medicine is made with the addition of alcohol, it can have a locally irritating effect (reddening of the skin, tightness, burning, itching), these sensations are often localized in the areas where the product is applied. The instructions contain information about the possibility of allergic reactions or photodermatitis (if treated surfaces are exposed to direct sunlight).
Overdose
eucalyptus oil applied to it .
When the drug penetrates the gastrointestinal tract diarrhea , vomiting, sweating, severe agitation, gradually turning into a fainting state are observed Sometimes acidosis , depression of the central nervous and cardiovascular systems occurs. Urine is typically green in color. If help is not provided in time, pulmonary edema , myocardial infarction , and liver and kidney damage are possible.
Therapy: gastric lavage with a solution of olive or other vegetable oil, taking enterosorbents . It is not recommended to artificially induce vomiting. Forced diuresis is effective .
Contraindications
If allergic manifestations (rash, swelling) occur while using Nitrofungin, you should immediately stop using the drug. Some patients experienced increased skin sensitivity to the components during the first application of the product; in this case, it is necessary to reduce the concentration of the drug. The instructions indicate that the solution is prohibited for use in children under 3 years of age. For women during pregnancy, the solution is prescribed if the expected benefit to the mother outweighs the risk to the fetus. The medication should not be used while breastfeeding.
Analogs
Level 4 ATC code matches: Myconorm
Undecin
Gentian violet
Zinkundan
Exoderil
Exiter
Batrafen
Lotseril
Lamisil Dermgel
Lamisil Uno
Lamisil
Salicylic acid
Salicylic ointment
Keto Plus
Exifin
Fungoterbin
Mycoseptin
Thermikon
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Baziron AS
Analogues of the drug are: Amorolac, Lamisil, Lamisil Uno, Lamikon Dermgel, Lamifen, Mikolak, Mikofin, Salicylic acid, Terbizil, Fungoterbin, Exoderil, Terbinorm, Exifin, Nitrofungin Neo, Mikoseptin, Lamifast, Keto Plus .
Indications for use
The use of the drug is permissible only if the patient has an appropriate indication for such therapy. The medication is prescribed only after the patient has undergone a full examination. Diagnostics allows us to identify the causative agent of the disease and select the optimal treatment for it.
The medicine is suitable for the treatment of different types of fungi. The medicine is appropriate to use if there are the following indications:
- Candidiasis;
- Eczema;
- Lichen;
- Mycosis;
- Fungal infection of the nail plates, groin, hands and feet.
To prevent the development of infectious lesions, doctors recommend using the medication for prophylactic purposes. Even if, after all the measures taken, a person fails to protect himself from the disease, its course will not be so severe. “Nitrofungin” will destroy pathogenic microorganisms. Therefore, the patient will be able to avoid the spread of the pathogen to healthy areas of the body as a result of its active reproduction.
Nitrofungin price, where to buy
The price of Nitrofungin is about 50 rubles per bottle with a capacity of 25 ml.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Nitrofungin external solution
approx. 1% 25mlTeva Czech Enterprises s.r.o. RUB 325 order - Nitrofungin-Teva solution d/nar. approx. 1% fl. 25ml No. 3 Teva Czech Enterprises s.r.o.
RUR 614 order
Pharmacy Dialogue
- Nitrofungin (25ml bottle)Ivax Pharmaceuticals
RUB 329 order
- Nitrofungin (bottle 25ml)Teva
RUR 326 order
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Pharmacy24
- Nitrofungin 25 ml solution TEVA Czech Industries s.r.o., Czech Republic
57 UAH.order - Nitrofungin Neo 25ml solution TEVA Czech Industries s.r.o., Czech Republic
111 UAH order
pharmachologic effect
“Nitrofungin” helps against fungus because it contains chloronitrophenol. The active substance has the ability to penetrate the upper layers of the skin and keratin of hair and nails. It reaches the habitat of pathogenic microflora. The component successfully destroys the important basis of the structure of the pathogen, which is ergosterol. Because of this, the fungus is weakened from the inside and loses its resistance to medications. Therefore, with the help of the drug (you can additionally use ointment), huge colonies of infectious agents are destroyed.
The fungus may be accompanied by other diseases caused by infections and inflammatory processes. The solution solves this problem, as it successfully destroys microorganisms present in the affected areas.
The active substance "Nitrofungin" can penetrate the upper layers of the skin and accumulate in them for a limited period of time. Due to this property, the drug has a persistent antifungal effect and prevents relapse of the disease.
Active substance
Nitrofungin from the manufacturer IVAX
The active component of Nitrofungin is a substance with disinfectant properties – chloronitrophenol. This is a derivative of phenol, which took over its volatility, characteristic odor and ability to penetrate the skin. The solution has a color from yellow to yellow-green.
The active component of Nitrofungin Neo is tridecanamine undecylinate. It is a modified form of undecylic acid that is used in many antifungal drugs. The solution is transparent, pale yellow, with a faint alcoholic odor. The active ingredient is not absorbed through the skin into the bloodstream.
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How the drug works
Chlornitrophenol, which is part of the drug, can block the synthesis of ergosterol. This substance is part of the structure of cell membranes. If there is a lack of it, the growth and reproduction of pathogenic cells stops, toxic substances begin to accumulate in them, and they die.
Once on the affected nail, the components of the substance actively penetrate into the subungual bed and accumulate there in the concentration necessary to remove pathogenic cells. The therapeutic effect of the drug lasts for a long period of time, so treatment is often not carried out with it.
The solution is not able to be absorbed by skin cells and has an effect only on epithelial cells. Nitrofungin does not enter the bloodstream and has virtually no side effects.
Reviews
There are many positive reviews about this drug on the Internet. Why does Nitrofungin attract many consumers?
- it helps to quickly get rid of the fungus when used at an early stage of infection;
- it contains no toxic substances. They have a negative effect on the liver;
- the solution is safe and has few contraindications;
- with careful application, without touching the skin around the nail, there will be no complications;
- the drug is sold at the best price available to every consumer, sold in every pharmacy;
- the drug takes a long time to be consumed and, if used correctly, lasts for 1 year;
- using a dosed dropper, patients use the required amount of product at a time;
- improvements are noticeable a week after the first application;
- the drug can be used for a long time as prophylaxis;
- the solution is well absorbed, has a positive effect, and relieves unpleasant symptoms in 2 days.
There are consumers who are not satisfied with the use of Nitrofungin and speak negatively about it: the solution changes the color of the nail, it acquires a yellow tint. This is not a minus. The use of Nitrofungin is desirable in the winter and autumn seasons, when people wear closed shoes. It can be replaced with an analogue called Nitrofungin Neo.
Nitrofungin is an effective remedy for nail fungus. But it is not recommended to use it yourself. The doctor must examine the patient, study the symptoms and prescribe a drug and a regimen for its use.
In what form is the drug available and what does it contain?
In pharmacies, Nitrofungin is found in the form of a 1% alcohol solution of a yellow, yellow-green, odorless color. The medicine is sold in a dark glass bottle with a dropper attached to it. The bottles are packaged in disposable cardboard boxes.
Its active ingredient is Chlornitrophenol.
Additionally, Nitrofungin includes:
- triethylene glycol. The substance is a transparent liquid with a complex molecular composition. It accelerates the healing process of damaged skin areas and accelerates the process of cell regeneration;
- 96% ethanol. This is an alcohol that has a disinfecting, irritating, astringent effect;
- distilled water.
Pharmacological authorities
Pharmacodynamics.
Nitrofungin is an antimycotic agent for local stagnation. The medicinal product is characterized by an antiseptic and disinfectant effect on gram-positive and gram-negative bacteria, mycobacteria, and fungi. An active cause of dermatomycoses. It is fungistatic.
Pharmacokinetics.
Phenol is absorbed from the gut-intestinal tract, skin, and mucous membranes. Vin is metabolized by phenylglucuronide and phenylsulfate. A small part of phenol is oxidized to catecholamines and quinol. Metabolites are excreted from the seed, which can produce a light green color.
Overdose
Signs of overdose may appear when the surface of the skin is soaked in phenol and the surface of the skin is soaked in dry skin. When phenol is wetted on the skin, it is necessary to remove the stubbornness of the clothes and wash the skin with a large amount of water, and then with algae oil. You can also use macrogol 300 or eucalyptus oil.
Rapid use of phenol leads to local swelling, resulting in pain, nausea, vomiting, increased sweating and diarrhea. Awakening may occur initially, after which the patient may become restless. Suppression of the central nervous system and subsequent insufficiency of the cardiovascular and respiratory systems can cause fatal complications. Sometimes the development of acidosis is avoided, and rarely hemolysis and methemoglobinemia with cyanosis. The cut begins to bloom green. At other times, beware of the development of swollen legs, deterioration of the myocardium and, as a result, low liver function, which can lead to insufficiency of the functions of these organs.
Once the phenol has been absorbed from the tubes, wash the tube with olive oil or other almond oil to dilute the phenol and prevent further absorption. You can also take assets from Vugilla. Do not click on the vomit piece. It is necessary to wash the boat with warm water. Forcing diuresis is also effective. In cases of hemolysis, a replacement blood transfusion is necessary.
Price
Prices for medicines vary significantly within the state and even within the same city. The cost of each medicine depends on the pricing policy of the pharmacy chain and many other factors. Czech Nitrofungin solution costs 280-340 rubles. The price of the Israeli counterpart is in a similar range. Nitrofungin Neo can cost 300-400 rubles. It is very rare in domestic pharmacies.
Different forms are in approximately the same price category
