Levorin - instructions for use, indications, release form, composition, dosage and price

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Manufacturers: Biosynthesis

Active ingredients

• Levorin

Disease class

• Changes in skin structure
• Carriage of the causative agent of another infectious disease
• Candidal stomatitis
• Candidiasis of the skin and nails
• Candidiasis of the vulva and vagina (N77.1*)
• Candidiasis of other localizations
• Cystitis
• Urethritis and urethral syndrome
• Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere

Clinical and pharmacological group

• Antifungal antibiotics

Pharmacological action

• Antifungal
• Fungicidal

Pharmacological group

• Antifungal agents

What is Levorin

The drug Levorin is a natural antibiotic with a fungicidal effect against fungal microflora. Its main substance, levorin, exhibits high activity and destroys a number of pathogenic pathogens. The product is produced by the Russian pharmaceutical companies Biosintez and GNIISKLS; it has its own contraindications, method of use and application features specified in the instructions.

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Storage

The drug Levorin must be placed in a room where the temperature is from 0 to 5 degrees. In addition, this room should be dark and dry. The room should also be cool (the drug is usually stored in the refrigerator).

If these conditions are met, Levorin can be taken for two years. After the expiration date, further use of the medicine is strictly prohibited. The medicinal product must be disposed of by placing it in the trash.

Compound

The main component of the composition is the sodium salt of levorin. Its therapeutic activity is measured in units of action - for 1 mg of tablets, suppositories or ointments there are at least 10 thousand such units. Auxiliary components of candles are a fat base with cocoa butter and confectionery fat, tablets - lactose, magnesium stearate, polyvinylpyrrolidone and colloidal silicon dioxide, ointments - petroleum jelly and lanolin.

Contraindications

Levorin is contraindicated in:

• high susceptibility to the components included in the drug;
• liver or kidney failure;
• acute gastrointestinal diseases;
• pancreatitis;
• pregnancy and lactation ;
• peptic ulcer;
• stomach ulcer.

Release form

Levorin comes in three main forms. Their differences:

pharmachologic effect

The antifungal agent has a fungicidal effect against pathogenic yeast-like fungi of the genus Candida. The drug contains a large number of conjugated double bonds, which are characterized by increased tropism for sterol compounds of the fungal plasma membrane. By interacting with them, double bonds increase the permeability of the cell wall, which leads to the exchange of cytosolic components with the external environment and cell lysis.

The product is effective against Trichomonas and Candida albicans strains. Once inside, the components of Levorin are practically not absorbed by the gastrointestinal tract, and therefore are not metabolized in the liver or other organs. They are excreted unchanged through the intestines with feces. There are no other data on the pharmacokinetics of the drug.

Reviews

Reviews about this medicine are usually positive. This is due to the high effectiveness of the product. In addition, among the positive reviews, people note the convenient method of administration. The drug also has a low cost, which does not put a strain on citizens’ pockets. On the forums you can find reviews not only from patients, but also from specialists who are aware of the peculiarities of taking the medicine.

Doctors note that in 90% of cases the drug has the expected effect. You can also find neutral reviews from specialists on the Internet. Doctors note the lack of effect due to improper use of the drug. The drug Levorin has a number of negative aspects, among which it is noted that the drug is quite difficult to get at the pharmacy, as well as the presence of a large number of contraindications.

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Indications for use

Instructions for use provide a list of indications for which Levorin is used. These include:

• candidiasis of the gastrointestinal tract caused by a yeast-like fungus from the genus Candida;
• trichomoniasis is a sexually transmitted disease caused by Trichomonas vaginalis, which threatens to develop into prostatitis;
• fungal infections of the mucous membranes, epidermis, female genital organs;
• cystitis is an infectious inflammation of the bladder that threatens to become chronic;
• urethritis is a pathological inflammatory process in the urethra, accompanied by pain when urinating, ulcers inside the cavity of the urinary canal;
• vulvovaginitis – inflammation of the genital organs in childhood and old age;
• as part of complex therapy for prostate hypertrophy;
• prevention of candidiasis - a condition in which the body contains parasites, but the disease does not develop.

Instructions for use of Levorin

Each form of release of the product has its own instructions for use. Thus, the ointment is used with caution in children under two years of age. For prostate hypertrophy in men, the use of Levorin reduces dysuric symptoms and sometimes the size of the adenoma. It is possible to use the drug as an additional drug in the treatment of prostate hypertrophy. When treating with tablets, liver function is regularly monitored during the course.

If severe side effects develop, drug therapy is discontinued and a substitute is prescribed instead. You cannot select the medicine yourself or change its dosage - this should only be done by a doctor. Some formats are used for gargling and mouthwash for candidiasis. In this case, due care must be taken so that the medicine does not enter the esophagus or respiratory tract.

Pills

According to the instructions, Levorin tablets can be used orally. Examples of dosages:

• For candidiasis of the intestines or other organs of the digestive tract, the drug is prescribed 1 pc. up to 4 times a day for a course of 10 days. In severe forms of the disease, treatment lasts 12 days.
• For children under two years old, the dosage is 25–30 thousand units per kg of body weight per day, 2–6 years old – 20–25 thousand units per 1 g of weight, over 6 years old – 250 thousand units 4 times a day. Therapy lasts a week, sometimes extended to 14 days.
• For local mucosal candidiasis caused by yeast-like microorganisms, tablets of 500 thousand units can be used. Adults take 1 tablet 4 times a day, children 3–10 years old take a quarter of a tablet, 10–15 years old take half a dose, after 15 years an adult dosage is prescribed. The course of treatment is 1-2 weeks.

According to reviews, the product effectively copes with mucus formation and the accumulation of thrush. Before use, doctors do an analysis of the sensitivity of microflora to the drug. For children's use, you can use a suspension - it is made from a powder having a concentration of 2-4 million units of levorin per bottle. Chilled water is added to the contents to the mark and shaken until smooth before each use. One teaspoon (5 ml) of the resulting solution contains 100 thousand units. The dosage of the suspension is no different from tablets.

Ointment

As stated in the instructions, Levorin ointment is used externally or as a rinse. For paronychia, erosions in the interdigital area, lesions of skin folds with peeling against the background of the growth of yeast-like fungi, apply it to the skin 1-2 times a day for 7-10 days. For diseases of the oral cavity or inflammation of the mucous membrane, the ointment is diluted 1:500 and used for rinsing.

The solution is applied up to three times a day for a three-week course. If the genital organs of women are affected (the fungus has settled on the mucous membrane), use the same remedy. Soak a cotton swab with the solution and insert it into the vagina. Treatment lasts 15–20 days. Levorin is contraindicated for use in case of uterine bleeding; this reduces the effectiveness of the drug and can aggravate the problem.

Candles

According to the instructions, Levorin suppositories are used intravaginally for genital candidiasis in women or purulent trichomoniasis. The drug helps with internal thrush. It is inserted deep into the vagina once a day, preferably at night. When using, you need to lie on your back, spread your knees and push the suppository inside. Treatment lasts 15–20 days until the symptoms are eliminated. Before administering suppositories, you must wash your hands and do the same after.

Side effects

The patient’s body can give a response, which is usually expressed in diseases and conditions such as:

• Vomiting, headache, diarrhea, dizziness, nausea, as well as pain in the abdomen, loss of appetite;
• Hives, itching, redness of the skin, swelling of the face.

Overdose

In the event of an overdose, a person experiences symptoms such as:

• Head pain, dizziness;
• Diarrhea, vomiting, constipation;
• Decreased appetite;
• Fever, chills, heat;
• Severe itching, redness of the skin;
• Irritation.

If you have signs of an overdose, you need to stop taking the drug. Next, the patient is advised to go to the hospital to receive medical care.

Contraindications

It is not recommended to take this medicine if you have such concomitant diseases and conditions as:

• Severe form of liver or kidney failure;
• Pancreatitis;
• Stomach ulcer;
• Acute diseases of the gastrointestinal tract;
• Duodenal ulcer.

Caution: Levorin can be prescribed for mild to moderate renal or liver failure. In addition, the medicine is carefully prescribed for the treatment of young patients under 2 years of age.

Pregnancy period

If it is impossible to stop the drug, then taking it is allowed, however, the girl must always be under the supervision of a doctor, i.e. stay in hospital. Only such a measure will allow monitoring the negative impact on the fetus.

During breastfeeding you should refrain from taking the medicine. If it is not possible to replace the drug Levorin with a safe analogue, then taking the drug is allowed, however, before starting treatment, the issue of stopping breastfeeding must be decided.

Analogs

The drug can be replaced with products with the same therapeutic effect, with a similar or different active component. Analogues of the drug are:

• Allylchep – hypolipidemic and antimicrobial oral drops based on onion bulb extract;
• Enterofuril - antibacterial capsules and suspensions containing nifuroxazide;
• Ersefuril - antimicrobial capsules based on nifuroxazide;
• Stopdiar - antibacterial tablets against diarrhea containing nifuroxazide as the main component;
• Bevisal - antiseptic intestinal tablets based on belladonna extract, bismuth subnitrate, phenyl salicylate;
• Bacteriophage is an antibacterial solution for oral administration containing pyobacteriophage, a mixture of filtrates of bacterial phagolysates.

Price

All forms of the drug are sold in pharmacies or on Internet sites with a prescription. Products are stored at a temperature no higher than 4 degrees. Tablets and suppositories can be stored for 1 year, ointment for 2 years. The diluted suspension can be stored for no longer than a week. Approximate cost of funds and their analogues in Moscow:

special instructions

In this section you can find useful information.

Driving

The medicine may affect the driver while driving.

Pregnancy

During pregnancy, it is highly undesirable to take Levolin. This is due to the fact that the active substance can have a detrimental effect on the fetus.

It is also not recommended to take this drug while breastfeeding.

Admission in childhood

This drug can be taken from 2 years of age.

Use for kidney problems

Taking the drug is contraindicated if kidney function is damaged.

Use for liver dysfunction

Taking the medication is contraindicated if the liver function is impaired.

Release from pharmacy

Only by prescription from a doctor.

Medicine and alcohol

Taking medication and alcohol are two incompatible things.

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