"Novocain": instructions for use, composition, indications and contraindications

• December 2, 2018
• Other drugs
• Inna Makagon

"Novocain" belongs to the pharmacological group of local anesthetic drugs. The medicine is used for local anesthesia of tissues in the area of ​​surgical operations or invasive diagnostic and therapeutic procedures.

The medication is a clear solution. The active component of the drug is the substance procaine. Its concentration in one milliliter is 5 milligrams (0.5% solution).

The solution is placed in glass ampoules of two, five, ten milliliters. There are ten ampoules in total in the package. The drug is also available in 200 milliliter bottles. What Novocain is used for can be found in this article.

Pharmacological properties

The active component of the drug has a local anesthetic effect. After administration, it leads to a decrease in the sensitivity of tissues in this area.

The duration of local anesthesia varies from half an hour to an hour.

In the instructions, the manufacturer indicates that Novocain has the following pharmacological effect:

• antitoxic;
• antihistamine;
• anti-inflammatory;
• desensitizing;
• analgesic;
• antiarrhythmic;
• relieves excitability of the heart muscle and spasms of smooth muscles;
• reduces blood pressure;
• brings you out of shock.

Release form

The most common and popular release forms in medicine

There are other forms of release: gel, ointment, spray with procaine, solution.

Spray

There is no spray called Novocaine, but its active component procaine is part of another medication with a local analgesic effect. This is Menovazin.

Gel

The drug released in this form is absorbed faster into the skin due to its water base. Therefore, if it is necessary to act on muscles and relieve their spasm, it is preferable to use a product in the form of a gel.

Ointment

Apply to a wound or area of ​​skin affected by eczema. The concentration of the active substance is 5 and 10%.

The ointment is applied to the wound or to the area of ​​skin affected by eczema.

Solution

The release of the drug in ampoules or a bottle allows it to be used for injections, in the form of compresses and as a rinse solution.

How to breed?

Before an injection of Novocaine is given, it is necessary to do a test that will show whether the patient has individual sensitivity to the components of the drug.

If swelling or redness appears on the skin, the medication cannot be used. If the test is negative, the medication can be diluted in accordance with the recommendations given in the instructions.

To blockade, you need to dilute the medication in this way:

• distilled water is brought to a boil and cooled (it can be replaced with saline solution);
• Novocaine should be used in low concentrations, no more than 0.5%;
• after mixing, the temperature of the solution should vary in the range of 37-38 degrees.

Reviews from doctors

Ivan Nikolaevich, 56 years old, Volgograd

There is no need to endure the pain: if there is an exacerbation of hemorrhoids, make a lotion with Novocaine 0.5% or buy suppositories. This drug is not absorbed into the blood, but acts locally. Yes, it does not replace treatment, but it will help alleviate the condition and get you to the doctor.

Olga Vasilievna, 45 years old, Moscow

I always recommend that my patients with chronic hemorrhoids keep suppositories with this anesthetic at home in case of sudden pain.

Indications and methods of use

The medication in liquid form is indicated for use in situations in which the patient requires anesthesia:

• spinal;
• epidural;
• conductor;
• infiltration;
• intraosseous;
• anesthesia of the mucous membranes of the ENT organs;
• paranephric and vagosympathetic, paravertebral and circular blockade;
• to potentiate the effect of drugs used for general anesthesia;
• to eliminate painful sensations of any intensity and nature;
• to extend the period of action of Penicillin, by dissolving it;
• as an adjuvant in the drug therapy of certain pathologies, which are most often diagnosed in patients of older age groups.

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Is it possible to take Novocaine for hemorrhoids?

For hemorrhoids, this remedy will reduce pain. The drug is used mainly in the form of rectal suppositories. Before use, it is necessary to cleanse the intestines with an enema. Because Novocaine is a local medication; you should not inject it too deeply; you should try to hold it near the sphincter so that the anesthetic effect manifests itself in the area of ​​hemorrhoid formation.

Chronic

For chronic hemorrhoids, the drug is used in case of relapse to alleviate the condition and weaken the blood supply to the hemorrhoids.

During exacerbation

In case of exacerbation of hemorrhoidal nodes, Novocaine is used in combination with antihemorrhoidal drugs, because is not an independent medicine. It is necessary only to relieve pain and to enhance the effectiveness of the healing substance.

Instructions for use of Novocaine in ampoules intramuscularly

Intramuscular administration of the drug is indicated for the development of the following pathological conditions:

• atherosclerosis;
• endarteritis;
• hypertension;
• bronchial asthma;
• spasms of cerebral and coronary vessels;
• joint diseases of an infectious or rheumatic nature.

Mostly older people face such pathologies. Their treatment is carried out in a hospital setting.

An injection is made into the muscle tissue, during which a 2.0% solution in a volume of 5 ml is injected. People receive injections three times a week.

The course of such therapy is 12 injections. After this, a ten-day break is taken. Over the course of a year, patients undergo four courses of intramuscular therapy.

If the patient has hypersensitivity to the components of the drug, he is initially prescribed a 2.0% solution in an amount of 2.0 ml.

If there are no side effects, the dose of the next injection is increased by 1.0 ml. It is gradually transferred to 5.0 ml per injection.

Overdose

According to the instructions for Novocain, if the prescribed pharmacological dosage is exceeded, the following unpleasant conditions may occur:

• Paleness of the skin.
• Nausea.
• Disorientation (the inability to identify one’s own personality, the place of its physical location, the period in which it resides or its social affiliation).
• Vomit.
• Dizziness.
• Tachypnea (impaired breathing, which may be caused by certain pathological processes).
• Tachycardia (sharp increase in heart rate, a sign of serious disorders).
• Arterial hypotension (persistent or regular decrease in blood pressure below the standard).
• Methemoglobinemia.
• Hyperhidrosis (a pathological process that is accompanied by excessive sweating throughout the body or only in certain areas).
• Increased heart rate.
• Feeling of fear.
• Apnea (a pathological disease that is caused by an etiological factor leading to short-term cessation of breathing during sleep).
• Acute heart diseases.
• Hallucinations (images that appear in the mind without a specific external stimulus).
• Motor agitation (a pathological process characterized by motor restlessness of varying degrees of intensity, often accompanied by speech excitation).
• Neurasthenia (a mental illness from the group of neuroses, which manifests itself in excessive irritability, as well as fatigue, loss of the ability for prolonged mental and physical stress).
• Tremor (movements of the legs, arms or torso, which are provoked by muscle spasms and are associated with a temporary delay in corrective afferent signals).

Treatment of poisoning is carried out only in a medical facility. It includes detoxification and symptomatic therapy.

Contraindications

The instructions supplied by the manufacturer with each package of Novocain note the following contraindications:

• hypersensitivity to the active component of the solution and excipients;
• It is prohibited to use the medicine for children under twelve years of age;
• The liquid should be used very carefully in patients over 65 years of age, pregnant women, and nursing mothers;
• pronounced changes in fibrous tissues.

special instructions

The use of Novocaine is permitted only for adults and children over 12 years of age.

Caution should be exercised when taking medication in the following cases:

• driving a car, working with dangerous mechanisms, because procaine inhibits brain activity and causes weakness and drowsiness;
• previous myocardial infarction;
• simultaneous use with drugs that lower blood pressure.

During pregnancy and lactation

During pregnancy, this drug is contraindicated. In extreme cases, the drug is used only after examination by a doctor and in compliance with all prescribed dosages for a short period of time.

During pregnancy, this drug is contraindicated.

The effect of the drug during breastfeeding has not been fully studied. There is a risk of disruption of the functioning of the mammary glands and disappearance of milk.

Use in childhood

Doctors rarely prescribe Novocaine to children under 12 years of age. At a younger age, it is used only if the expected effect exceeds the risk.

Side effects

The manufacturer of the drug indicates in the instructions that during its use in people, in particular in young patients, the following side effects may occur:

• the skin begins to itch very much, and rashes characteristic of allergic reactions appear on them;
• there is pain in the sternum area;
• drowsiness increases;
• the body feels weak;
• suffer from headaches;
• possible development of arrhythmia, bradycardia;
• your head starts to feel dizzy;
• pressure surges are observed;
• Peripheral vasodilation develops;
• collapse may occur, etc.

Its use in cosmetology and plastic surgery

Due to its qualities, the drug is widely used both in plastic surgery and cosmetology. Carrying out corrections of the body and face for the purpose of skin rejuvenation and using Novocaine ensures the absence of painful sensations. Its use is also possible during the recovery period, especially in case of prolonged pain.

The minimum number of possible side effects when using novocaine makes it possible to use it even with increased sensitivity of the body. Many cosmetic procedures are also performed using this drug if they affect the deeper layers of the epidermis, causing unpleasant and painful sensations.

• and so on.

By the way, it also helps a lot if there is pain with hemorrhoids, as well as.

Pain relief with Novocaine during hair removal is described in the video below:

Price

In pharmacy chains, the price of liquid for injection can vary from 35 to 50 rubles per package containing five ampoules.

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Conditions for dispensing from pharmacies

Solutions for injections and infusions are sold strictly according to prescription; suppositories - without a prescription.

What is the price

Approximate prices for Novocaine of various concentrations and forms of release:

Drug interactions

Novocaine enhances the inhibitory effect of other drugs on the nervous system.

Concomitant use with warfarin, dalteparin sodium, ardeparin sodium, danaparoid sodium, heparin, enoxaparin sodium increases the risk of bleeding.

When combined with monoamine oxidase inhibitors (procarbazine, furazolidone, selegiline), the likelihood of a decrease in blood pressure increases.

Vasoconstrictors, including epinephrine, phenylephrine, methoxamine, help prolong the period of local anesthetic effect.

Since the effect of procaine (especially when used in high doses) reduces the antimyasthenic effect of anticholinesterase drugs, adjustment of the dosage regimen is required when treating myasthenia gravis.

The metabolism of Novocaine is reduced by cholinesterase inhibitors (cyclophosphamide, antimyasthenic drugs, demecaria bromide, thiotepa, ecothiopathy iodide).

Para-aminobenzoic acid (a metabolite of procaine) is an antagonist of sulfonamide drugs, therefore, when used simultaneously, their bactericidal effect is reduced.

The search for Einhorn

Einhorn, a professor at the Munich Polytechnic Institute, had been searching for a substitute for cocaine since 1890. He sorted through the decomposition products of cocaine one after another, involving numerous graduate students in the work. One of them was Richard Willstetter, who managed everything with extraordinary ease. The chemical structure of cocaine was still unknown, and synthesis remained a dream. Willstetter wanted to implement it. Germany was experiencing a chemical boom, there were no free places in academic laboratories, and Einhorn allowed his former graduate student to work in a student laboratory for a fee from 7 to 10 in the morning.

Things were going well until Einhorn got the crazy idea that Willstetter wanted to steal his future victory. At dawn, as the young man prepared to begin the extraction, Einhorn burst into the laboratory and in an extremely harsh tone forbade any work with cocaine. Willstätter, in confusion, rushed to his teacher Adolf Bayer (famous for the discovery of barbiturates). What should I do? The young, unknown specialist has nowhere to go from Einhorn. And the wise Bayer gave advice: work with atropine, which is very similar to cocaine; This is how you get close to synthesis, and when you do it, it will be all the same - the winners are not judged.

Indeed, two years later, in 1898, Willstetter synthesized cocaine, and Einhorn relented. Now the structure of the drug molecule is known, and it is possible to construct a substitute - roughly speaking, take from the cocaine molecule the link responsible for anesthesia, discarding the one responsible for addiction.